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3JCJ
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STRUCTURES OF RIBOSOME-BOUND INITIATION FACTOR 2 REVEAL THE MECHANISM OF SUBUNIT ASSOCIATION
Descriptor:5S ribosomal RNA, 30S ribosomal protein S18, 30S ribosomal protein S21, ...
Authors:Sprink, T., Ramrath, D.J.F., Yamamoto, H., Yamamoto, K., Loerke, J., Ismer, J., Hildebrand, P.W., Scheerer, P., Buerger, J., Mielke, T., Spahn, C.M.T.
Deposit date:2015-12-18
Release date:2016-03-09
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structures of ribosome-bound initiation factor 2 reveal the mechanism of subunit association.
Sci Adv, 2, 2016
3JCN
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STRUCTURES OF RIBOSOME-BOUND INITIATION FACTOR 2 REVEAL THE MECHANISM OF SUBUNIT ASSOCIATION: INITIATION COMPLEX I
Descriptor:50S ribosomal protein L32, 50S ribosomal protein L33, 50S ribosomal protein L34, ...
Authors:Sprink, T., Ramrath, D.J.F., Yamamoto, H., Yamamoto, K., Loerke, J., Ismer, J., Hildebrand, P.W., Scheerer, P., Buerger, J., Mielke, T., Spahn, C.M.T.
Deposit date:2016-01-04
Release date:2016-03-09
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Structures of ribosome-bound initiation factor 2 reveal the mechanism of subunit association.
Sci Adv, 2, 2016
4CXG
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REGULATION OF THE MAMMALIAN ELONGATION CYCLE BY 40S SUBUNIT ROLLING: A EUKARYOTIC-SPECIFIC RIBOSOME REARRANGEMENT
Descriptor:18S RRNA - H44, 28S RRNA - H89, ELONGATION FACTOR 1A, ...
Authors:Budkevich, T.V., Giesebrecht, J., Behrmann, E., Loerke, J., Ramrath, D.J.F., Mielke, T., Ismer, J., Hildebrand, P., Tung, C.-S., Nierhaus, K.H., Sanbonmatsu, K.Y., Spahn, C.M.T.
Deposit date:2014-04-07
Release date:2014-07-16
Last modified:2017-08-23
Method:ELECTRON MICROSCOPY (8.7 Å)
Cite:Regulation of the Mammalian Elongation Cycle by Subunit Rolling: A Eukaryotic-Specific Ribosome Rearrangement.
Cell(Cambridge,Mass.), 158, 2014
4CXH
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REGULATION OF THE MAMMALIAN ELONGATION CYCLE BY 40S SUBUNIT ROLLING: A EUKARYOTIC-SPECIFIC RIBOSOME REARRANGEMENT
Descriptor:18S RRNA - H44, 28S RRNA - H89, ELONGATION FACTOR 1A, ...
Authors:Budkevich, T.V., Giesebrecht, J., Behrmann, E., Loerke, J., Ramrath, D.J.F., Mielke, T., Ismer, J., Hildebrand, P., Tung, C.-S., Nierhaus, K.H., Sanbonmatsu, K.Y., Spahn, C.M.T.
Deposit date:2014-04-07
Release date:2014-07-16
Last modified:2017-08-23
Method:ELECTRON MICROSCOPY (8.9 Å)
Cite:Regulation of the Mammalian Elongation Cycle by Subunit Rolling: A Eukaryotic-Specific Ribosome Rearrangement.
Cell(Cambridge,Mass.), 158, 2014
4UJE
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REGULATION OF THE MAMMALIAN ELONGATION CYCLE BY 40S SUBUNIT ROLLING: A EUKARYOTIC-SPECIFIC RIBOSOME REARRANGEMENT
Descriptor:TRNA-LYS, TRNA-PHE, Messenger RNA, ...
Authors:Budkevich, T.V., Giesebrecht, J., Behrmann, E., Loerke, J., Ramrath, D.J.F., Mielke, T., Ismer, J., Hildebrand, P., Tung, C.-S., Nierhaus, K.H., Sanbonmatsu, K.Y., Spahn, C.M.T.
Deposit date:2014-04-05
Release date:2014-07-16
Last modified:2017-08-30
Method:ELECTRON MICROSCOPY (6.9 Å)
Cite:Regulation of the Mammalian Elongation Cycle by Subunit Rolling: A Eukaryotic-Specific Ribosome Rearrangement.
Cell(Cambridge,Mass.), 158, 2014
5FLX
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MAMMALIAN 40S HCV-IRES COMPLEX
Descriptor:18S RRNA, 40S RIBOSOMAL PROTEIN SA, 40S RIBOSOMAL PROTEIN S3A, ...
Authors:Yamamoto, H., Collier, M., Loerke, J., Ismer, J., Schmidt, A., Hilal, T., Sprink, T., Yamamoto, K., Mielke, T., Burger, J., Shaikh, T.R., Dabrowski, M., Hildebrand, P.W., Scheerer, P., Spahn, C.M.T.
Deposit date:2015-10-28
Release date:2015-12-23
Last modified:2017-08-30
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Molecular Architecture of the Ribosome-Bound Hepatitis C Virus Internal Ribosomal Entry Site RNA.
Embo J., 34, 2015
6GZ3
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TRNA TRANSLOCATION BY THE EUKARYOTIC 80S RIBOSOME AND THE IMPACT OF GTP HYDROLYSIS, TRANSLOCATION-INTERMEDIATE-POST-1 (TI-POST-1)
Descriptor:28S ribosomal RNA, ap/P-site tRNA, mRNA, ...
Authors:Flis, J., Holm, M., Rundlet, E.J., Loerke, J., Hilal, T., Dabrowski, M., Buerger, J., Mielke, T., Blanchard, S.C., Spahn, C.M.T., Budkevich, T.V.
Deposit date:2018-07-03
Release date:2018-12-05
Last modified:2018-12-19
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:tRNA Translocation by the Eukaryotic 80S Ribosome and the Impact of GTP Hydrolysis.
Cell Rep, 25, 2018
6GZ4
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TRNA TRANSLOCATION BY THE EUKARYOTIC 80S RIBOSOME AND THE IMPACT OF GTP HYDROLYSIS, TRANSLOCATION-INTERMEDIATE-POST-2 (TI-POST-2)
Descriptor:ribosomal protein uL2, ribosomal protein uS2, ribosomal protein uL3, ...
Authors:Flis, J., Holm, M., Rundlet, E.J., Loerke, J., Hilal, T., Dabrowski, M., Buerger, J., Mielke, T., Blanchard, S.C., Spahn, C.M.T., Budkevich, T.V.
Deposit date:2018-07-03
Release date:2018-12-05
Last modified:2019-02-06
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:tRNA Translocation by the Eukaryotic 80S Ribosome and the Impact of GTP Hydrolysis.
Cell Rep, 25, 2018
6GZ5
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TRNA TRANSLOCATION BY THE EUKARYOTIC 80S RIBOSOME AND THE IMPACT OF GTP HYDROLYSIS, TRANSLOCATION-INTERMEDIATE-POST-3 (TI-POST-3)
Descriptor:28S ribosomal RNA, P/P-site-tRNA, mRNA, ...
Authors:Flis, J., Holm, M., Rundlet, E.J., Loerke, J., Hilal, T., Dabrowski, M., Buerger, J., Mielke, T., Blanchard, S.C., Spahn, C.M.T., Budkevich, T.V.
Deposit date:2018-07-03
Release date:2018-12-05
Last modified:2018-12-19
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:tRNA Translocation by the Eukaryotic 80S Ribosome and the Impact of GTP Hydrolysis.
Cell Rep, 25, 2018
4UJC
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MAMMALIAN 80S HCV-IRES INITIATION COMPLEX WITH EIF5B POST-LIKE STATE
Descriptor:TRNA, EIF5B, HCV-IRES, ...
Authors:Yamamoto, H., Unbehaun, A., Loerke, J., Behrmann, E., Marianne, C., Burger, J., Mielke, T., Spahn, C.M.T.
Deposit date:2014-06-18
Release date:2014-07-30
Last modified:2017-08-23
Method:ELECTRON MICROSCOPY (9.5 Å)
Cite:Structure of the Mammalian 80S Initiation Complex with Initiation Factor 5B on Hcv-Ires RNA.
Nat.Struct.Mol.Biol., 21, 2014
4UJD
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MAMMALIAN 80S HCV-IRES INITIATION COMPLEX WITH EIF5B PRE-LIKE STATE
Descriptor:28S Ribosomal RNA, 5.8S Ribosomal RNA, 5S Ribosomal RNA, ...
Authors:Yamamoto, H., Unbehaun, A., Loerke, J., Behrmann, E., Marianne, C., Burger, J., Mielke, T., Spahn, C.M.T.
Deposit date:2014-06-18
Release date:2014-07-30
Last modified:2017-08-23
Method:ELECTRON MICROSCOPY (8.9 Å)
Cite:Structure of the Mammalian 80S Initiation Complex with Eif5B on Hcv Ires
Nat.Struct.Mol.Biol., 21, 2014
5AJ0
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CRYO ELECTRON MICROSCOPY OF ACTIVELY TRANSLATING HUMAN POLYSOMES (POST STATE).
Descriptor:5.8S ribosomal RNA, 5S ribosomal RNA, 60S ribosomal protein L8, ...
Authors:Behrmann, E., Loerke, J., Budkevich, T.V., Yamamoto, K., Schmidt, A., Penczek, P.A., Vos, M.R., Burger, J., Mielke, T., Scheerer, P., Spahn, C.M.T.
Deposit date:2015-02-19
Release date:2015-05-20
Last modified:2018-11-21
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural Snapshots of Actively Translating Human Ribosomes
Cell(Cambridge,Mass.), 161, 2015
5M1J
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NONSTOP RIBOSOMAL COMPLEX BOUND WITH DOM34 AND HBS1
Descriptor:Protein DOM34, 40S ribosomal protein S0-A, 40S ribosomal protein S26-B, ...
Authors:Hilal, T., Yamamoto, H., Loerke, J., Buerger, J., Mielke, T., Spahn, C.M.T.
Deposit date:2016-10-07
Release date:2017-01-18
Last modified:2019-02-20
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural insights into ribosomal rescue by Dom34 and Hbs1 at near-atomic resolution.
Nat Commun, 7, 2016
6GBZ
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50S RIBOSOMAL SUBUNIT ASSEMBLY INTERMEDIATE STATE 5
Descriptor:23S ribosomal RNA, 50S ribosomal protein L2, 50S ribosomal protein L3, ...
Authors:Nikolay, R., Hilal, T., Qin, B., Loerke, J., Buerger, J., Mielke, T., Spahn, C.M.T.
Deposit date:2018-04-16
Release date:2018-06-20
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural Visualization of the Formation and Activation of the 50S Ribosomal Subunit during In Vitro Reconstitution.
Mol. Cell, 70, 2018
6GC0
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50S RIBOSOMAL SUBUNIT ASSEMBLY INTERMEDIATE STATE 4
Descriptor:23S ribosomal RNA, 5S ribosomal RNA, 50S ribosomal protein L2, ...
Authors:Nikolay, R., Hilal, T., Qin, B., Loerke, J., Buerger, J., Mielke, T., Spahn, C.M.T.
Deposit date:2018-04-16
Release date:2018-06-20
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural Visualization of the Formation and Activation of the 50S Ribosomal Subunit during In Vitro Reconstitution.
Mol. Cell, 70, 2018
6GC4
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50S RIBOSOMAL SUBUNIT ASSEMBLY INTERMEDIATE STATE 3
Descriptor:50S ribosomal protein L25, 23S ribosomal RNA, 50S ribosomal protein L2, ...
Authors:Nikolay, R., Hilal, T., Qin, B., Loerke, J., Buerger, J., Mielke, T., Spahn, C.M.T.
Deposit date:2018-04-17
Release date:2018-07-04
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Structural Visualization of the Formation and Activation of the 50S Ribosomal Subunit during In Vitro Reconstitution.
Mol. Cell, 70, 2018
6GC6
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50S RIBOSOMAL SUBUNIT ASSEMBLY INTERMEDIATE STATE 2
Descriptor:23S ribosomal RNA, 50S ribosomal protein L2, 50S ribosomal protein L3, ...
Authors:Nikolay, R., Hilal, T., Qin, B., Loerke, J., Buerger, J., Mielke, T., Spahn, C.M.T.
Deposit date:2018-04-17
Release date:2018-07-04
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Structural Visualization of the Formation and Activation of the 50S Ribosomal Subunit during In Vitro Reconstitution.
Mol. Cell, 70, 2018
6GC7
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50S RIBOSOMAL SUBUNIT ASSEMBLY INTERMEDIATE STATE 1
Descriptor:23S ribosomal RNA, 50S ribosomal protein L3, 50S ribosomal protein L4, ...
Authors:Nikolay, R., Hilal, T., Qin, B., Loerke, J., Buerger, J., Mielke, T., Spahn, C.M.T.
Deposit date:2018-04-17
Release date:2018-06-20
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Structural Visualization of the Formation and Activation of the 50S Ribosomal Subunit during In Vitro Reconstitution.
Mol. Cell, 70, 2018
6GC8
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50S RIBOSOMAL SUBUNIT ASSEMBLY INTERMEDIATE - 50S REC*
Descriptor:23S ribosomal RNA, 5S ribosomal RNA, 50S ribosomal protein L2, ...
Authors:Nikolay, R., Hilal, T., Qin, B., Loerke, J., Buerger, J., Mielke, T., Spahn, C.M.T.
Deposit date:2018-04-17
Release date:2018-06-20
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural Visualization of the Formation and Activation of the 50S Ribosomal Subunit during In Vitro Reconstitution.
Mol. Cell, 70, 2018
4V5M
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TRNA TRANLOCATION ON THE 70S RIBOSOME: THE PRE-TRANSLOCATIONAL TRANSLOCATION INTERMEDIATE TI(PRE)
Descriptor:16S RRNA, 30S RIBOSOMAL PROTEIN S2, 30S RIBOSOMAL PROTEIN S3, ...
Authors:Ratje, A.H., Loerke, J., Mikolajka, A., Bruenner, M., Hildebrand, P.W., Starosta, A.L., Doenhoefer, A., Connell, S.R., Fucini, P., Mielke, T., Whitford, P.C., Onuchic, J.N., Yu, Y., Sanbonmatsu, K.Y., Hartmann, R.K., Penczek, P.A., Wilson, D.N., Spahn, C.M.T.
Deposit date:2010-10-01
Release date:2014-07-09
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (7.8 Å)
Cite:Head Swivel on the Ribosome Facilitates Translocation by Means of Intra-Subunit tRNA Hybrid Sites.
Nature, 468, 2010
4V5N
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TRNA TRANSLOCATION ON THE 70S RIBOSOME: THE POST- TRANSLOCATIONAL TRANSLOCATION INTERMEDIATE TI(POST)
Descriptor:16S RRNA, 30S RIBOSOMAL PROTEIN S2, 30S RIBOSOMAL PROTEIN S3, ...
Authors:Ratje, A.H., Loerke, J., Mikolajka, A., Bruenner, M., Hildebrand, P.W., Starosta, A.L., Doenhoefer, A., Connell, S.R., Fucini, P., Mielke, T., Whitford, P.C., Onuchic, J.N., Yu, Y., Sanbonmatsu, K.Y., Hartmann, R.K., Penczek, P.A., Wilson, D.N., Spahn, C.M.T.
Deposit date:2010-10-21
Release date:2014-07-09
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (7.6 Å)
Cite:Head Swivel on the Ribosome Facilitates Translocation by Means of Intra-Subunit tRNA Hybrid Sites.
Nature, 468, 2010
4V6T
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STRUCTURE OF THE BACTERIAL RIBOSOME COMPLEXED BY TMRNA-SMPB AND EF-G DURING TRANSLOCATION AND MLD-LOADING
Descriptor:16S ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Ramrath, D.J.F., Yamamoto, H., Rother, K., Wittek, D., Pech, M., Mielke, T., Loerke, J., Scheerer, P., Ivanov, P., Teraoka, Y., Shpanchenko, O., Nierhaus, K.H., Spahn, C.M.T.
Deposit date:2012-01-27
Release date:2014-07-09
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (8.3 Å)
Cite:The complex of tmRNA-SmpB and EF-G on translocating ribosomes.
Nature, 485, 2012
4V7B
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VISUALIZATION OF TWO TRNAS TRAPPED IN TRANSIT DURING EF-G-MEDIATED TRANSLOCATION
Descriptor:16S ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Ramrath, D.J.F., Lancaster, L., Sprink, T., Mielke, T., Loerke, J., Noller, H.F., Spahn, C.M.T.
Deposit date:2013-10-27
Release date:2014-07-09
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (6.8 Å)
Cite:Visualization of two transfer RNAs trapped in transit during elongation factor G-mediated translocation.
Proc.Natl.Acad.Sci.USA, 110, 2013
4V68
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T. THERMOPHILUS 70S RIBOSOME IN COMPLEX WITH MRNA, TRNAS AND EF-TU.GDP.KIRROMYCIN TERNARY COMPLEX, FITTED TO A 6.4 A CRYO-EM MAP.
Descriptor:16S rRNA, 30S ribosomal protein S2, 30S ribosomal protein S4, ...
Authors:Schuette, J.-C., Spahn, C.M.T.
Deposit date:2008-12-11
Release date:2014-07-09
Last modified:2015-03-25
Method:ELECTRON MICROSCOPY (6.4 Å)
Cite:GTPase activation of elongation factor EF-Tu by the ribosome during decoding
Embo J., 28, 2009
5LM7
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CRYSTAL STRUCTURE OF THE LAMBDA N-NUS FACTOR COMPLEX
Descriptor:Transcription termination/antitermination protein NusA, N utilization substance protein B homolog, 30S ribosomal protein S10, ...
Authors:Said, N., Santos, K., Weber, G., Wahl, M.C.
Deposit date:2016-07-29
Release date:2017-04-05
Last modified:2017-12-06
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:Structural basis for lambda N-dependent processive transcription antitermination.
Nat Microbiol, 2, 2017
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