5NPY
 
 | | Crystal structure of Helicobacter pylori flagellar hook protein FlgE2 | | Descriptor: | Flagellar basal body protein, TRIS-HYDROXYMETHYL-METHYL-AMMONIUM | | Authors: | Loconte, V, Zanotti, G, Kekez, I, Matkovic-Calogovic, D. | | Deposit date: | 2017-04-19 | | Release date: | 2017-11-15 | | Last modified: | 2017-12-27 | | Method: | X-RAY DIFFRACTION (2.292 Å) | | Cite: | Structural characterization of FlgE2 protein from Helicobacter pylori hook.
FEBS J., 284, 2017
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6R66
 | | Crystal structure of transthyretin in complex with CHF5075, a flurbiprofen analogue | | Descriptor: | 1-[4-[3,5-bis(chloranyl)phenyl]-3-fluoranyl-phenyl]cyclopropane-1-carboxylic acid, Transthyretin | | Authors: | Loconte, V, Menozzi, I, Ferrari, A, Berni, R, Zanotti, G. | | Deposit date: | 2019-03-26 | | Release date: | 2019-09-11 | | Last modified: | 2019-11-06 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | Structure-activity relationships of flurbiprofen analogues as stabilizers of the amyloidogenic protein transthyretin.
J.Struct.Biol., 208, 2019
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6R67
 | | Crystal structure of transthyretin in complex with CHF5075, a flurbiprofen analogue | | Descriptor: | (2~{R})-2-[4-(3,5-dimethylphenyl)-3-fluoranyl-phenyl]propanoic acid, Transthyretin | | Authors: | Loconte, V, Menozzi, I, Ferrari, A, Berni, R, Zanotti, G. | | Deposit date: | 2019-03-26 | | Release date: | 2019-09-11 | | Last modified: | 2019-11-06 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | Structure-activity relationships of flurbiprofen analogues as stabilizers of the amyloidogenic protein transthyretin.
J.Struct.Biol., 208, 2019
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6R68
 | | Crystal structure of transthyretin in complex with CHF4795, a flurbiprofen analogue | | Descriptor: | (2~{R})-2-[4-[3,5-bis(chloranyl)phenyl]-3-fluoranyl-phenyl]propanoic acid, Transthyretin | | Authors: | Loconte, V, Menozzi, I, Ferrari, A, Berni, R, Zanotti, G. | | Deposit date: | 2019-03-26 | | Release date: | 2019-09-11 | | Last modified: | 2019-11-06 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | Structure-activity relationships of flurbiprofen analogues as stabilizers of the amyloidogenic protein transthyretin.
J.Struct.Biol., 208, 2019
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6R6I
 | | Crystal structure of transthyretin mutant A25T in complex with CHF5074, a flurbiprofen analogue | | Descriptor: | 1-(3',4'-dichloro-2-fluorobiphenyl-4-yl)cyclopropanecarboxylic acid, PHOSPHATE ION, Transthyretin | | Authors: | Loconte, V, Menozzi, I, Ferrari, A, Berni, R, Zanotti, G. | | Deposit date: | 2019-03-27 | | Release date: | 2019-09-11 | | Last modified: | 2019-11-06 | | Method: | X-RAY DIFFRACTION (1.467 Å) | | Cite: | Structure-activity relationships of flurbiprofen analogues as stabilizers of the amyloidogenic protein transthyretin.
J.Struct.Biol., 208, 2019
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6SUH
 | | Crystal structure of human transthyretin in complex with 3-O-methyltolcapone, a tolcapone analogue | | Descriptor: | 3-O-methyltolcapone, Transthyretin | | Authors: | Loconte, V, Cianci, M, Menozzi, I, Sbravati, D, Sansone, F, Casnati, A, Berni, R. | | Deposit date: | 2019-09-14 | | Release date: | 2020-08-05 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.26 Å) | | Cite: | Interactions of tolcapone analogues as stabilizers of the amyloidogenic protein transthyretin.
Bioorg.Chem., 103, 2020
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6SUG
 | | Crystal structure of transthyretin in complex with 3-deoxytolcapone, a tolcapone analogue | | Descriptor: | 3-deoxytolcapone, Transthyretin | | Authors: | Loconte, V, Cianci, M, Menozzi, I, Sbravati, D, Sansone, F, Casnati, A, Berni, R. | | Deposit date: | 2019-09-14 | | Release date: | 2020-08-05 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.21 Å) | | Cite: | Interactions of tolcapone analogues as stabilizers of the amyloidogenic protein transthyretin.
Bioorg.Chem., 103, 2020
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8C85
 | | Crystal structure of human transthyretin in complex with 3-O-methyltolcapone analogue 1 | | Descriptor: | (3,5-dimethylphenyl)-(3-methoxy-5-nitro-4-oxidanyl-phenyl)methanone, Transthyretin | | Authors: | Poonsiri, T, Benini, S, Loconte, V, Cianci, M. | | Deposit date: | 2023-01-18 | | Release date: | 2024-01-17 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.19 Å) | | Cite: | 3-O-Methyltolcapone and Its Lipophilic Analogues Are Potent Inhibitors of Transthyretin Amyloidogenesis with High Permeability and Low Toxicity.
Int J Mol Sci, 25, 2023
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8C86
 | | Crystal structure of human transthyretin in complex with 3-O-methyltolcapone analogue 2 | | Descriptor: | (2,4-dimethylphenyl)-(3-methoxy-5-nitro-4-oxidanyl-phenyl)methanone, Transthyretin | | Authors: | Poonsiri, T, Benini, S, Loconte, V, Cianci, M. | | Deposit date: | 2023-01-18 | | Release date: | 2024-01-17 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.1 Å) | | Cite: | 3-O-Methyltolcapone and Its Lipophilic Analogues Are Potent Inhibitors of Transthyretin Amyloidogenesis with High Permeability and Low Toxicity.
Int J Mol Sci, 25, 2023
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4INN
 | | Protein HP1028 from the human pathogen Helicobacter pylori belongs to the lipocalin family | | Descriptor: | 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, HP1028 | | Authors: | Barison, N, Cendron, L, Loconte, V, Zanotti, G. | | Deposit date: | 2013-01-05 | | Release date: | 2013-07-31 | | Last modified: | 2014-02-05 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Protein HP1028 from the human pathogen Helicobacter pylori belongs to the lipocalin family.
Acta Crystallogr.,Sect.D, 69, 2013
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