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6GSN
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BU of 6gsn by Molmil
Structure of a partial yeast 48S preinitiation complex in closed conformation
Descriptor: 18S rRNA (1798-MER), 40S ribosomal protein S0, 40S ribosomal protein S1, ...
Authors:Llacer, J.L, Hussain, T, Ramakrishnan, V.
Deposit date:2018-06-14
Release date:2019-06-26
Last modified:2021-10-27
Method:ELECTRON MICROSCOPY (5.75 Å)
Cite:Large-scale movement of eIF3 domains during translation initiation modulate start codon selection.
Nucleic Acids Res., 2021
6GSM
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BU of 6gsm by Molmil
Structure of a partial yeast 48S preinitiation complex in open conformation.
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S0, 40S ribosomal protein S1, ...
Authors:Llacer, J.L, Hussain, T, Gordiyenko, Y, Ramakrishnan, V.
Deposit date:2018-06-14
Release date:2019-07-31
Last modified:2023-02-22
Method:ELECTRON MICROSCOPY (5.2 Å)
Cite:Large-scale movement of eIF3 domains during translation initiation modulate start codon selection.
Nucleic Acids Res., 2021
6FYX
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BU of 6fyx by Molmil
Structure of a partial yeast 48S preinitiation complex with eIF5 N-terminal domain (model C1)
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S0, 40S ribosomal protein S1, ...
Authors:Llacer, J.L, Hussain, T, Gordiyenko, Y, Ramakrishnan, V.
Deposit date:2018-03-12
Release date:2018-12-05
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.05 Å)
Cite:Translational initiation factor eIF5 replaces eIF1 on the 40S ribosomal subunit to promote start-codon recognition.
Elife, 7, 2018
6FYY
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BU of 6fyy by Molmil
Structure of a partial yeast 48S preinitiation complex with eIF5 N-terminal domain (model C2)
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S0, 40S ribosomal protein S1, ...
Authors:Llacer, J.L, Hussain, T, Gordiyenko, Y, Ramakrishnan, V.
Deposit date:2018-03-12
Release date:2018-12-05
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.05 Å)
Cite:Translational initiation factor eIF5 replaces eIF1 on the 40S ribosomal subunit to promote start-codon recognition.
Elife, 7, 2018
2JJ4
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BU of 2jj4 by Molmil
The complex of PII and acetylglutamate kinase from Synechococcus elongatus PCC7942
Descriptor: ACETYLGLUTAMATE KINASE, N-ACETYL-L-GLUTAMATE, NITROGEN REGULATORY PROTEIN P-II
Authors:Llacer, J.L, Marco-Marin, C, Gil-Ortiz, F, Fita, I, Rubio, V.
Deposit date:2007-07-04
Release date:2007-10-16
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.46 Å)
Cite:The Crystal Structure of the Complex of Pii and Acetylglutamate Kinase Reveals How Pii Controls the Storage of Nitrogen as Arginine
Proc.Natl.Acad.Sci.USA, 104, 2007
2V5H
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BU of 2v5h by Molmil
Controlling the storage of nitrogen as arginine: the complex of PII and acetylglutamate kinase from Synechococcus elongatus PCC 7942
Descriptor: ACETYLGLUTAMATE KINASE, CHLORIDE ION, GLYCEROL, ...
Authors:Llacer, J.L, Marco-Marin, C, Gil-Ortiz, F, Fita, I, Rubio, V.
Deposit date:2007-07-04
Release date:2007-10-16
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:The Crystal Structure of the Complex of Pii and Acetylglutamate Kinase Reveals How Pii Controls the Storage of Nitrogen as Arginine.
Proc.Natl.Acad.Sci.USA, 104, 2007
2XGX
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BU of 2xgx by Molmil
Crystal structure of transcription factor NtcA from Synechococcus elongatus (mercury derivative)
Descriptor: 2-OXOGLUTARIC ACID, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLOBAL NITROGEN REGULATOR, ...
Authors:Llacer, J.L, Castells, M.A, Rubio, V.
Deposit date:2010-06-08
Release date:2010-08-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structural Basis for the Regulation of Ntca-Dependent Transcription by Proteins Pipx and Pii.
Proc.Natl.Acad.Sci.USA, 107, 2010
2XKO
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BU of 2xko by Molmil
Crystal structure of the complex of NtcA with its transcriptional co- activator PipX
Descriptor: 2-OXOGLUTARIC ACID, GLOBAL NITROGEN REGULATOR, PIPX
Authors:Llacer, J.L, Castells, M.A, Rubio, V.
Deposit date:2010-07-11
Release date:2010-08-18
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural Basis for the Regulation of Ntca-Dependent Transcription by Proteins Pipx and Pii.
Proc.Natl.Acad.Sci.USA, 107, 2010
2XG8
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BU of 2xg8 by Molmil
Structural basis of gene regulation by protein PII: The crystal complex of PII and PipX from Synechococcus elongatus PCC 7942
Descriptor: NITROGEN REGULATORY PROTEIN P-II, PIPX
Authors:Llacer, J.L, Rubio, V.
Deposit date:2010-06-01
Release date:2010-08-18
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural Basis for the Regulation of Ntca-Dependent Transcription by Proteins Pipx and Pii.
Proc.Natl.Acad.Sci.USA, 107, 2010
2XKP
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BU of 2xkp by Molmil
NtcA from Synechococcus elongatus: active and inactive
Descriptor: 2-OXOGLUTARIC ACID, GLOBAL NITROGEN REGULATOR
Authors:Llacer, J.L, Castells, M.A, Rubio, V.
Deposit date:2010-07-11
Release date:2010-08-18
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Structural Basis for the Regulation of Ntca-Dependent Transcription by Proteins Pipx and Pii.
Proc.Natl.Acad.Sci.USA, 107, 2010
2XHK
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BU of 2xhk by Molmil
Crystal structure of transcription factor NtcA from Synechococcus elongatus bound to 2-oxoglutarate
Descriptor: 2-OXOGLUTARIC ACID, GLOBAL NITROGEN REGULATOR
Authors:Llacer, J.L, Castells, M.A, Rubio, V.
Deposit date:2010-06-17
Release date:2010-08-18
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Basis for the Regulation of Ntca-Dependent Transcription by Proteins Pipx and Pii.
Proc.Natl.Acad.Sci.USA, 107, 2010
3JAM
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BU of 3jam by Molmil
CryoEM structure of 40S-eIF1A-eIF1 complex from yeast
Descriptor: 18S rRNA, MAGNESIUM ION, RACK1, ...
Authors:Llacer, J.L, Hussain, T, Ramakrishnan, V.
Deposit date:2015-06-17
Release date:2015-08-12
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (3.46 Å)
Cite:Conformational Differences between Open and Closed States of the Eukaryotic Translation Initiation Complex.
Mol.Cell, 59, 2015
3JAP
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BU of 3jap by Molmil
Structure of a partial yeast 48S preinitiation complex in closed conformation
Descriptor: 18S rRNA, MAGNESIUM ION, METHIONINE, ...
Authors:Llacer, J.L, Hussain, T, Ramakrishnan, V.
Deposit date:2015-06-18
Release date:2015-08-12
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (4.9 Å)
Cite:Conformational Differences between Open and Closed States of the Eukaryotic Translation Initiation Complex.
Mol.Cell, 59, 2015
2JER
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BU of 2jer by Molmil
Agmatine deiminase of Enterococcus faecalis catalyzing its reaction.
Descriptor: AGMATINE DEIMINASE
Authors:Tavarez, S, Llacer, J.L, Rubio, V.
Deposit date:2007-01-19
Release date:2007-01-30
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:The Gene Cluster for Agmatine Catabolism of Enterococcus Faecalis: Study of Recombinant Putrescine Transcarbamylase and Agmatine Deiminase and a Snapshot of Agmatine Deiminase Catalyzing its Reaction.
J.Bacteriol., 189, 2007
6QG1
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BU of 6qg1 by Molmil
Structure of eIF2B-eIF2 (phosphorylated at Ser51) complex (model 2)
Descriptor: Eukaryotic translation initiation factor 2 subunit alpha, Eukaryotic translation initiation factor 2 subunit beta, Eukaryotic translation initiation factor 2 subunit gamma, ...
Authors:Llacer, J.L, Gordiyenko, Y, Ramakrishnan, V.
Deposit date:2019-01-10
Release date:2019-06-26
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structural basis for the inhibition of translation through eIF2 alpha phosphorylation.
Nat Commun, 10, 2019
6QG2
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BU of 6qg2 by Molmil
Structure of eIF2B-eIF2 (phosphorylated at Ser51) complex (model A)
Descriptor: Eukaryotic translation initiation factor 2 subunit alpha, Eukaryotic translation initiation factor 2 subunit beta, Eukaryotic translation initiation factor 2 subunit gamma, ...
Authors:Llacer, J.L, Gordiyenko, Y, Ramakrishnan, V.
Deposit date:2019-01-10
Release date:2019-06-26
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Structural basis for the inhibition of translation through eIF2 alpha phosphorylation.
Nat Commun, 10, 2019
6QG6
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BU of 6qg6 by Molmil
Structure of eIF2B-eIF2 (phosphorylated at Ser51) complex (model D)
Descriptor: Eukaryotic translation initiation factor 2 subunit alpha, Eukaryotic translation initiation factor 2 subunit beta, Eukaryotic translation initiation factor 2 subunit gamma, ...
Authors:Llacer, J.L, Gordiyenko, Y, Ramakrishnan, V.
Deposit date:2019-01-10
Release date:2019-06-26
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (4.65 Å)
Cite:Structural basis for the inhibition of translation through eIF2 alpha phosphorylation.
Nat Commun, 10, 2019
6QG0
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BU of 6qg0 by Molmil
Structure of eIF2B-eIF2 (phosphorylated at Ser51) complex (model 1)
Descriptor: Eukaryotic translation initiation factor 2 subunit alpha, Eukaryotic translation initiation factor 2 subunit beta, Eukaryotic translation initiation factor 2 subunit gamma, ...
Authors:Llacer, J.L, Gordiyenko, Y, Ramakrishnan, V.
Deposit date:2019-01-10
Release date:2019-06-26
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structural basis for the inhibition of translation through eIF2 alpha phosphorylation.
Nat Commun, 10, 2019
6QG3
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BU of 6qg3 by Molmil
Structure of eIF2B-eIF2 (phosphorylated at Ser51) complex (model B)
Descriptor: Eukaryotic translation initiation factor 2 subunit alpha, Eukaryotic translation initiation factor 2 subunit beta, Eukaryotic translation initiation factor 2 subunit gamma, ...
Authors:Llacer, J.L, Gordiyenko, Y, Ramakrishnan, V.
Deposit date:2019-01-10
Release date:2019-06-26
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (9.4 Å)
Cite:Structural basis for the inhibition of translation through eIF2 alpha phosphorylation.
Nat Commun, 10, 2019
6QG5
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BU of 6qg5 by Molmil
Structure of eIF2B-eIF2 (phosphorylated at Ser51) complex (model C)
Descriptor: Eukaryotic translation initiation factor 2 subunit alpha, Eukaryotic translation initiation factor 2 subunit beta, Eukaryotic translation initiation factor 2 subunit gamma, ...
Authors:Llacer, J.L, Gordiyenko, Y, Ramakrishnan, V.
Deposit date:2019-01-10
Release date:2019-06-26
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (10.1 Å)
Cite:Structural basis for the inhibition of translation through eIF2 alpha phosphorylation.
Nat Commun, 10, 2019
8P99
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BU of 8p99 by Molmil
SARS-CoV-2 S-protein:D614G mutant in 1-up conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1,Spike glycoprotein
Authors:Adhav, A, Forcada-Nadal, A, Marco-Marin, C, Lopez-Redondo, M.L, Llacer, J.L.
Deposit date:2023-06-05
Release date:2023-09-27
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:C-2 Thiophenyl Tryptophan Trimers Inhibit Cellular Entry of SARS-CoV-2 through Interaction with the Viral Spike (S) Protein.
J.Med.Chem., 66, 2023
8P9Y
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BU of 8p9y by Molmil
SARS-CoV-2 S protein S:D614G mutant in 3-down with binding site of an entry inhibitor
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SODIUM ION, ...
Authors:Adhav, A, Forcada-Nadal, A, Marco-Marin, C, Lopez-Redondo, M.L, Llacer, J.L.
Deposit date:2023-06-06
Release date:2023-09-27
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:C-2 Thiophenyl Tryptophan Trimers Inhibit Cellular Entry of SARS-CoV-2 through Interaction with the Viral Spike (S) Protein.
J.Med.Chem., 66, 2023
7QDG
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BU of 7qdg by Molmil
SARS-CoV-2 S protein S:A222V + S:D614G mutant 1-up
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Ginex, T, Marco-Marin, C, Wieczor, M, Mata, C.P, Krieger, J, Lopez-Redondo, M.L, Frances-Gomez, C, Ruiz-Rodriguez, P, Melero, R, Sanchez-Sorzano, C.O, Martinez, M, Gougeard, N, Forcada-Nadal, A, Zamora-Caballero, S, Gozalbo-Rovira, R, Sanz-Frasquet, C, Bravo, J, Rubio, V, Marina, A, Geller, R, Comas, I, Gil, C, Coscolla, M, Orozco, M, LLacer, J.L, Carazo, J.M.
Deposit date:2021-11-27
Release date:2022-05-25
Last modified:2022-08-24
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:The structural role of SARS-CoV-2 genetic background in the emergence and success of spike mutations: The case of the spike A222V mutation.
Plos Pathog., 18, 2022
7QDH
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BU of 7qdh by Molmil
SARS-CoV-2 S protein S:D614G mutant 1-up
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein,Fibritin
Authors:Ginex, T, Marco-Marin, C, Wieczor, M, Mata, C.P, Krieger, J, Lopez-Redondo, M.L, Frances-Gomez, C, Ruiz-Rodriguez, P, Melero, R, Sanchez-Sorzano, C.O, Martinez, M, Gougeard, N, Forcada-Nadal, A, Zamora-Caballero, S, Gozalbo-Rovira, R, Sanz-Frasquet, C, Bravo, J, Rubio, V, Marina, A, Geller, R, Comas, I, Gil, C, Coscolla, M, Orozco, M, LLacer, J.L, Carazo, J.M.
Deposit date:2021-11-27
Release date:2022-05-25
Last modified:2022-08-10
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:The structural role of SARS-CoV-2 genetic background in the emergence and success of spike mutations: The case of the spike A222V mutation.
Plos Pathog., 18, 2022
4OZN
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BU of 4ozn by Molmil
GlnK2 from Haloferax mediterranei complexed with ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Nitrogen regulatory protein P-II, SULFATE ION
Authors:Palanca, C, Pedro-Roig, L, Llacer, J.L, Camacho, M, Bonete, M.J, Rubio, V.
Deposit date:2014-02-17
Release date:2014-07-02
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The structure of a PII signaling protein from a halophilic archaeon reveals novel traits and high-salt adaptations.
Febs J., 281, 2014

 

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