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7F05
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BU of 7f05 by Molmil
Crystal structure of human cardiac calsequestrin bound with calcium
Descriptor: CALCIUM ION, Calsequestrin-2
Authors:Fan, X.X, Liu, X.X, Su, X.D, Wang, S.Q.
Deposit date:2021-06-03
Release date:2022-06-08
Method:X-RAY DIFFRACTION (2.298 Å)
Cite:Ca2+-dependent Formation of a Non-transmembrane Channel in a Calsequestrin-2 Dimer
To Be Published
4XRH
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BU of 4xrh by Molmil
Human DNA polymerase lambda- MgdTTP binary and complex with 6 paired DNA
Descriptor: DNA (5'-D(*CP*AP*GP*TP*AP*C)-3'), DNA (5'-D(P*GP*TP*AP*CP*TP*G)-3'), DNA polymerase lambda, ...
Authors:Liu, M.S, Tsai, M.D.
Deposit date:2015-01-21
Release date:2016-02-24
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural Mechanism for the Fidelity Modulation of DNA Polymerase lambda
J.Am.Chem.Soc., 138, 2016
4XQ8
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BU of 4xq8 by Molmil
Human DNA polymerase lambda- MgdATP binary complex and complex with 6 paired DNA
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*CP*AP*GP*TP*AP*C)-3'), DNA (5'-D(P*GP*TP*AP*CP*TP*G)-3'), ...
Authors:Tsai, M.D, Liu, M.S.
Deposit date:2015-01-19
Release date:2016-02-24
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.798 Å)
Cite:Structural Mechanism for the Fidelity Modulation of DNA Polymerase lambda
J.Am.Chem.Soc., 138, 2016
5CA7
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BU of 5ca7 by Molmil
Human DNA polymerase lambda- MgdGTP binary and complex with 6 paired DNA
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*AP*GP*TP*AP*C)-3'), DNA (5'-D(P*GP*TP*AP*CP*TP*G)-3'), ...
Authors:Liu, M.S, Tsai, M.D.
Deposit date:2015-06-29
Release date:2016-02-24
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.522 Å)
Cite:Structural Mechanism for the Fidelity Modulation of DNA Polymerase lambda
J.Am.Chem.Soc., 138, 2016
5CB1
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BU of 5cb1 by Molmil
Apo enzyme of human Polymerase lambda
Descriptor: DNA polymerase lambda
Authors:Liu, M.S, Tsai, M.D.
Deposit date:2015-06-30
Release date:2016-02-24
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural Mechanism for the Fidelity Modulation of DNA Polymerase lambda
J.Am.Chem.Soc., 138, 2016
5CHG
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BU of 5chg by Molmil
Human DNA polymerase lambda L431A mutant- MgdGTP binary and complex with 6 paired DNA
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*AP*GP*TP*AP*C)-3'), DNA (5'-D(P*GP*TP*AP*CP*TP*G)-3'), ...
Authors:Liu, M.S, Tsai, M.D.
Deposit date:2015-07-10
Release date:2016-02-24
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural Mechanism for the Fidelity Modulation of DNA Polymerase lambda
J.Am.Chem.Soc., 138, 2016
5CP2
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BU of 5cp2 by Molmil
Human DNA polymerase lambda L431A mutant- Apoenzyme and complex with 6 paired DNA
Descriptor: DNA (5'-D(*CP*AP*GP*TP*AP*C)-3'), DNA (5'-D(P*GP*TP*AP*CP*TP*G)-3'), DNA polymerase lambda, ...
Authors:Liu, M.S, Tsai, M.D.
Deposit date:2015-07-21
Release date:2016-02-24
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:Structural Mechanism for the Fidelity Modulation of DNA Polymerase lambda
J.Am.Chem.Soc., 138, 2016
5CJ7
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BU of 5cj7 by Molmil
Human DNA polymerase lambda L431A mutant- MgdTTP binary and complex with 6 paired DNA
Descriptor: DNA (5'-D(*CP*AP*GP*TP*AP*C)-3'), DNA (5'-D(P*GP*TP*AP*CP*TP*G)-3'), DNA polymerase lambda, ...
Authors:Liu, M.S, Tsai, M.D.
Deposit date:2015-07-14
Release date:2016-02-24
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.901 Å)
Cite:Structural Mechanism for the Fidelity Modulation of DNA Polymerase lambda
J.Am.Chem.Soc., 138, 2016
5CR0
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BU of 5cr0 by Molmil
Human DNA polymerase lambda L431A mutant- MgdCTP binary and complex with 6 paired DNA
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*AP*GP*TP*AP*C)-3'), DNA (5'-D(P*GP*TP*AP*CP*TP*G)-3'), ...
Authors:Liu, M.S, Tsai, M.D.
Deposit date:2015-07-22
Release date:2016-02-24
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structural Mechanism for the Fidelity Modulation of DNA Polymerase lambda
J.Am.Chem.Soc., 138, 2016
5DDM
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BU of 5ddm by Molmil
Human DNA polymerase lambda- Apoenzyme and complex with 6 paired DNA
Descriptor: DNA (5'-D(*CP*AP*GP*TP*AP*C)-3'), DNA (5'-D(P*GP*TP*AP*CP*TP*G)-3'), DNA polymerase lambda, ...
Authors:Liu, M.S, Tsai, M.D.
Deposit date:2015-08-25
Release date:2016-02-24
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.802 Å)
Cite:Structural Mechanism for the Fidelity Modulation of DNA Polymerase lambda
J.Am.Chem.Soc., 138, 2016
5CWR
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BU of 5cwr by Molmil
Crystal Structure of human DNA polymerase lambda L431A mutant in complex with a one nucleotide DNA gap and dCTP
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*CP*AP*GP*TP*AP*C)-3'), ...
Authors:Liu, M.S, Tsai, M.D.
Deposit date:2015-07-28
Release date:2016-02-24
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Mechanism for the Fidelity Modulation of DNA Polymerase lambda
J.Am.Chem.Soc., 138, 2016
5DDY
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BU of 5ddy by Molmil
Binary complex of human Polymerase lambda with dCTP
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA polymerase lambda, MAGNESIUM ION, ...
Authors:Liu, M.S, Tsai, M.D.
Deposit date:2015-08-25
Release date:2016-02-24
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.36 Å)
Cite:Structural Mechanism for the Fidelity Modulation of DNA Polymerase lambda
J.Am.Chem.Soc., 138, 2016
5DKW
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BU of 5dkw by Molmil
Ternary crystal structure of polymerase lambda with a GA mispair at the primer terminus with Ca2+ in the active
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*CP*AP*GP*TP*AP*C)-3'), ...
Authors:Liu, M.S, Tsai, M.D.
Deposit date:2015-09-04
Release date:2016-02-24
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.689 Å)
Cite:Structural Mechanism for the Fidelity Modulation of DNA Polymerase lambda
J.Am.Chem.Soc., 138, 2016
5XZW
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BU of 5xzw by Molmil
Crystal structure of Rad53 1-466
Descriptor: Serine/threonine-protein kinase RAD53
Authors:Weng, J.H, Tsai, M.D.
Deposit date:2017-07-14
Release date:2017-10-11
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Phospho-Priming Confers Functionally Relevant Specificities for Rad53 Kinase Autophosphorylation
Biochemistry, 56, 2017
5XZV
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BU of 5xzv by Molmil
Crystal structure of Rad53 1-466 in complex with AMP-PNP
Descriptor: PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Serine/threonine-protein kinase RAD53
Authors:Weng, J.H, Tsai, M.D.
Deposit date:2017-07-14
Release date:2017-10-11
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Phospho-Priming Confers Functionally Relevant Specificities for Rad53 Kinase Autophosphorylation
Biochemistry, 56, 2017
5ZLC
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BU of 5zlc by Molmil
Binary complex of human DNA Polymerase Mu with MndGTP
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA-directed DNA/RNA polymerase mu, MANGANESE (II) ION, ...
Authors:Chang, Y.K, Wu, W.J, Tsai, M.D.
Deposit date:2018-03-27
Release date:2019-05-29
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions.
J.Am.Chem.Soc., 141, 2019
6AK5
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BU of 6ak5 by Molmil
Binary Complex of Human DNA Polymerase Mu with MnGTP
Descriptor: DNA-directed DNA/RNA polymerase mu, GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, ...
Authors:Chang, Y.K, Wu, W.J, Tsai, M.D.
Deposit date:2018-08-30
Release date:2019-05-29
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions.
J.Am.Chem.Soc., 141, 2019
6AK9
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BU of 6ak9 by Molmil
Pre-catalytic Ternary Complex of Human DNA Polymerase Mu with Templating Cytosine and Incoming Ca-8oxodGTP
Descriptor: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 8-OXO-2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Chang, Y.K, Wu, W.J, Tsai, M.D.
Deposit date:2018-08-30
Release date:2019-05-29
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions.
J.Am.Chem.Soc., 141, 2019
6AEC
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BU of 6aec by Molmil
Binary complex of human DNA Polymerase Mu with MnATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, DNA-directed DNA/RNA polymerase mu, MANGANESE (II) ION, ...
Authors:Chang, Y.K, Wu, W.J, Tsai, M.D.
Deposit date:2018-08-04
Release date:2019-05-29
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions.
J.Am.Chem.Soc., 141, 2019
6AK8
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BU of 6ak8 by Molmil
Pre-catalytic Ternary Complex of Human DNA Polymerase Mu with Templating Adenine and Incoming Ca-8oxodGTP
Descriptor: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 8-OXO-2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Chang, Y.K, Wu, W.J, Tsai, M.D.
Deposit date:2018-08-30
Release date:2019-05-29
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions.
J.Am.Chem.Soc., 141, 2019
6AKH
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BU of 6akh by Molmil
Pre-catalytic Ternary Complex of Human DNA Polymerase Mu with Templating Adenine and Incoming Mn-dUMPNPP
Descriptor: 1,2-ETHANEDIOL, 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
Authors:Chang, Y.K, Wu, W.J, Tsai, M.D.
Deposit date:2018-08-31
Release date:2019-05-29
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions.
J.Am.Chem.Soc., 141, 2019
6AEH
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BU of 6aeh by Molmil
Binary complex of human DNA Polymerase Mu with MnUTP
Descriptor: DNA-directed DNA/RNA polymerase mu, MANGANESE (II) ION, SULFATE ION, ...
Authors:Chang, Y.K, Wu, W.J, Tsai, M.D.
Deposit date:2018-08-04
Release date:2019-05-29
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions.
J.Am.Chem.Soc., 141, 2019
6AK6
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BU of 6ak6 by Molmil
Binary Complex of Human DNA Polymerase Mu with MnCTP
Descriptor: CYTIDINE-5'-TRIPHOSPHATE, DNA-directed DNA/RNA polymerase mu, MANGANESE (II) ION, ...
Authors:Chang, Y.K, Wu, W.J, Tsai, M.D.
Deposit date:2018-08-30
Release date:2019-05-29
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions.
J.Am.Chem.Soc., 141, 2019
6IPJ
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BU of 6ipj by Molmil
Binary Complex of Human DNA Polymerase Mu with MndTTP
Descriptor: DNA-directed DNA/RNA polymerase mu,DNA-directed DNA/RNA polymerase mu, MANGANESE (II) ION, SULFATE ION, ...
Authors:Chang, Y.K, Wu, W.J, Tsai, M.D.
Deposit date:2018-11-03
Release date:2019-05-29
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions.
J.Am.Chem.Soc., 141, 2019
6IPG
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BU of 6ipg by Molmil
Post-catalytic Complex of Human DNA Polymerase Mu with Templating Cytosine and Mg-8oxodGMP
Descriptor: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DNA (5'-D(*CP*GP*GP*CP*CP*TP*AP*CP*G)-3'), ...
Authors:Chang, Y.K, Wu, W.J, Tsai, M.D.
Deposit date:2018-11-03
Release date:2019-05-29
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions.
J.Am.Chem.Soc., 141, 2019

 

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