Author results

5GRJ
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CRYSTAL STRUCTURE OF HUMAN PD-L1 WITH MONOCLONAL ANTIBODY AVELUMAB
分子名称:avelumab H chain, avelumab L chain, Programmed cell death 1 ligand 1
著者Liu, K., Tan, S., Chai, Y., Chen, D., Song, H., Zhang, C.W.-H., Shi, Y., Liu, J., Tan, W., Lyu, J., Gao, S., Yan, J., Qi, J., Gao, G.F.
登録日2016-08-11
公開日2016-11-02
最終更新日2017-01-18
実験手法X-RAY DIFFRACTION (3.206 Å)
主引用文献Structural basis of anti-PD-L1 monoclonal antibody avelumab for tumor therapy.
Cell Res., 27, 2017
4QRH
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MOLECULAR MECHANISM AND EVOLUTION OF GUANYLATE KINASE REGULATION BY (P)PPGPP
分子名称:Guanylate kinase, SULFATE ION, MAGNESIUM ION, ...
著者Liu, K., Krasny, K., Myers, A.R., Satyshur, K.A., Keck, J.L., Wnag, J.D.
登録日2014-07-01
公開日2015-02-25
最終更新日2015-03-04
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Molecular Mechanism and Evolution of Guanylate Kinase Regulation by (p)ppGpp.
Mol.Cell, 57, 2015
6C1A
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MBD2 IN COMPLEX WITH METHYLATED DNA
分子名称:Methyl-CpG-binding domain protein 2, dna strand 1, complement to dna strand 1, ...
著者Liu, K., Xu, C., Tempel, W., Arrowsmith, C.H., Bountra, C., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
登録日2018-01-04
公開日2018-02-14
最終更新日2018-05-23
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structural basis for the ability of MBD domains to bind methyl-CG and TG sites in DNA.
J. Biol. Chem., 293, 2018
6C1Y
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MBD OF HUMAN MECP2 IN COMPLEX WITH METHYLATED DNA
分子名称:Methyl-CpG-binding protein 2, 12-mer DNA, UNKNOWN ATOM OR ION
著者Liu, K., Bian, C., Tempel, W., Wernimont, A.K., Arrowsmith, C.H., Bountra, C., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
登録日2018-01-05
公開日2018-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献mbd of human mecp2 in complex with methylated DNA
to be published
6C2F
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MBD2 IN COMPLEX WITH METHYLATED DNA
分子名称:Methyl-CpG-binding domain protein 2, 12-mer DNA, UNKNOWN ATOM OR ION
著者Liu, K., Xu, C., Tempel, W., Arrowsmith, C.H., Bountra, C., Edwards, A.M., Min, J., Structural Genomics Consortium, Structural Genomics Consortium (SGC)
登録日2018-01-08
公開日2018-02-14
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献MBD2 in complex with methylated DNA
to be published
6CC8
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CRYSTAL STRUCTURE MBD3 MBD DOMAIN IN COMPLEX WITH METHYLATED CPG DNA
分子名称:Methyl-CpG-binding domain protein 3, methylated CpG DNA, UNKNOWN ATOM OR ION
著者Liu, K., Tempel, W., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
登録日2018-02-06
公開日2018-04-04
最終更新日2019-05-22
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural analyses reveal that MBD3 is a methylated CG binder.
Febs J., 2019
6CCG
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CRYSTAL STRUCTURE MBD3 MBD DOMAIN IN COMPLEX WITH METHYLATED CPG DNA
分子名称:Methyl-CpG-binding domain protein 3, DNA, UNKNOWN ATOM OR ION
著者Liu, K., Tempel, W., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
登録日2018-02-07
公開日2018-05-09
最終更新日2019-05-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural analyses reveal that MBD3 is a methylated CG binder.
Febs J., 2019
6CEU
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MBD3 MBD IN COMPLEX WITH METHYLATED, NON-PALINDROMIC CPG DNA: ALTERNATIVE INTERPRETATION OF CRYSTALLOGRAPHIC DATA
分子名称:Methyl-CpG-binding domain protein 3, DNA (5'-D(*GP*CP*CP*AP*GP*(5CM)P*GP*TP*TP*GP*GP*C)-3'), DNA (5'-D(*GP*CP*CP*AP*AP*(5CM)P*GP*CP*TP*GP*GP*C)-3'), ...
著者Liu, K., Tempel, W., Wernimont, A.K., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
登録日2018-02-12
公開日2018-05-09
最終更新日2019-05-22
実験手法X-RAY DIFFRACTION (2.005 Å)
主引用文献Structural analyses reveal that MBD3 is a methylated CG binder.
Febs J., 2019
6CEV
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MBD3 MBD IN COMPLEX WITH METHYLATED, NON-PALINDROMIC CPG DNA: ALTERNATIVE INTERPRETATION OF CRYSTALLOGRAPHIC DATA
分子名称:Methyl-CpG-binding domain protein 3, DNA (5'-D(*GP*CP*CP*AP*GP*(5CM)P*GP*TP*TP*GP*GP*C)-3'), DNA (5'-D(*GP*CP*CP*AP*AP*(5CM)P*GP*CP*TP*GP*GP*C)-3'), ...
著者Liu, K., Tempel, W., Wernimont, A.K., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
登録日2018-02-12
公開日2018-05-09
最終更新日2019-05-22
実験手法X-RAY DIFFRACTION (2.005 Å)
主引用文献Structural analyses reveal that MBD3 is a methylated CG binder.
Febs J., 2019
6CNQ
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MBD2 IN COMPLEX WITH METHYLATED DNA
分子名称:Methyl-CpG-binding domain protein 2, DNA (5'-D(*GP*CP*CP*AP*AP*(5CM)P*GP*TP*TP*GP*GP*C)-3'), UNKNOWN ATOM OR ION
著者Liu, K., Xu, C., Min, J., Structural Genomics Consortium (SGC)
登録日2018-03-08
公開日2018-03-28
最終更新日2018-05-23
実験手法X-RAY DIFFRACTION (2.151 Å)
主引用文献Structural basis for the ability of MBD domains to bind methyl-CG and TG sites in DNA.
J. Biol. Chem., 293, 2018
6D1T
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COMPLEX OF MBD1-MBD AND METHYLATED DNA
分子名称:Methyl-CpG-binding domain protein 1, DNA (5'-D(*GP*CP*CP*AP*AP*(5CM)P*GP*TP*TP*GP*GP*C)-3'), UNKNOWN ATOM OR ION
著者Liu, K., Xu, C., Tempel, W., Arrowsmith, C.H., Bountra, C., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
登録日2018-04-12
公開日2018-05-09
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Complex of MBD1-MBD and methylated DNA
to be published
5GR7
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MOUSE MHC CLASS I H-2KD WITH A MERS-COV-DERIVED PEPTIDE 37-1
分子名称:H-2 class I histocompatibility antigen, K-D alpha chain, Beta-2-microglobulin, ...
著者Liu, K., Chai, Y., Qi, J., Tan, W., Liu, W.J., Gao, G.F.
登録日2016-08-08
公開日2017-06-07
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Protective T Cell Responses Featured by Concordant Recognition of Middle East Respiratory Syndrome Coronavirus-Derived CD8+ T Cell Epitopes and Host MHC.
J. Immunol., 198, 2017
5GSB
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MOUSE MHC CLASS I H-2KD WITH A MERS-COV-DERIVED PEPTIDE 37-3
分子名称:H-2 class I histocompatibility antigen, K-D alpha chain, Beta-2-microglobulin, ...
著者Liu, K., Chai, Y., Qi, J., Tan, W., Liu, W.J., Gao, G.F.
登録日2016-08-15
公開日2017-07-12
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (1.801 Å)
主引用文献Protective T Cell Responses Featured by Concordant Recognition of Middle East Respiratory Syndrome Coronavirus-Derived CD8+ T Cell Epitopes and Host MHC.
J. Immunol., 198, 2017
5GSR
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MOUSE MHC CLASS I H-2KD WITH A MERS-COV-DERIVED PEPTIDE I5A
分子名称:Beta-2-microglobulin, H-2 class I histocompatibility antigen, K-D alpha chain, ...
著者Liu, K., Chai, Y., Qi, J., Tan, W., Liu, W.J., Gao, G.F.
登録日2016-08-17
公開日2017-04-26
実験手法X-RAY DIFFRACTION (2.198 Å)
主引用文献Protective T Cell Responses Featured by Concordant Recognition of Middle East Respiratory Syndrome Coronavirus-Derived CD8+ T Cell Epitopes and Host MHC.
J. Immunol., 198, 2017
5GSV
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MOUSE MHC CLASS I H-2KD WITH A MERS-COV-DERIVED PEPTIDE 142-5
分子名称:H-2 class I histocompatibility antigen, K-D alpha chain, Beta-2-microglobulin, ...
著者Liu, K., Chai, Y., Qi, J., Tan, W., Liu, W.J., Gao, G.F.
登録日2016-08-17
公開日2017-04-26
実験手法X-RAY DIFFRACTION (1.996 Å)
主引用文献Protective T Cell Responses Featured by Concordant Recognition of Middle East Respiratory Syndrome Coronavirus-Derived CD8+ T Cell Epitopes and Host MHC.
J. Immunol., 198, 2017
5GSX
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MOUSE MHC CLASS I H-2KD WITH A MERS-COV-DERIVED PEPTIDE 142-2
分子名称:H-2 class I histocompatibility antigen, K-D alpha chain, Beta-2-microglobulin, ...
著者Liu, K., Chai, Y., Qi, J., Tan, W., Liu, W.J., Gao, G.F.
登録日2016-08-17
公開日2017-06-07
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Protective T Cell Responses Featured by Concordant Recognition of Middle East Respiratory Syndrome Coronavirus-Derived CD8+ T Cell Epitopes and Host MHC.
J. Immunol., 198, 2017
3OMC
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STRUCTURE OF HUMAN SND1 EXTENDED TUDOR DOMAIN IN COMPLEX WITH THE SYMMETRICALLY DIMETHYLATED ARGININE PIWIL1 PEPTIDE R4ME2S
分子名称:Staphylococcal nuclease domain-containing protein 1, SYNTHETIC PEPTIDE, CHLORIDE ION
著者Lam, R., Liu, K., Guo, Y.H., Bian, C.B., Xu, C., MacKenzie, F., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Min, J., Structural Genomics Consortium (SGC)
登録日2010-08-26
公開日2010-09-15
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Structural basis for recognition of arginine methylated Piwi proteins by the extended Tudor domain.
Proc.Natl.Acad.Sci.USA, 107, 2010
3OMG
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STRUCTURE OF HUMAN SND1 EXTENDED TUDOR DOMAIN IN COMPLEX WITH THE SYMMETRICALLY DIMETHYLATED ARGININE PIWIL1 PEPTIDE R14ME2S
分子名称:Staphylococcal nuclease domain-containing protein 1, dimethylated arginine peptide R14me2s
著者Lam, R., Liu, K., Guo, Y.H., Bian, C.B., Xu, C., MacKenzie, F., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Min, J., Structural Genomics Consortium (SGC)
登録日2010-08-26
公開日2010-09-08
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural basis for recognition of arginine methylated Piwi proteins by the extended Tudor domain.
Proc.Natl.Acad.Sci.USA, 107, 2010
4O64
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ZINC FINGERS OF KDM2B
分子名称:Lysine-specific demethylase 2B, ZINC ION, UNKNOWN ATOM OR ION
著者Liu, K., Xu, C., Tempel, W., Walker, J.R., Arrowsmith, C.H., Bountra, C., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
登録日2013-12-20
公開日2014-04-16
最終更新日2018-01-03
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献DNA Sequence Recognition of Human CXXC Domains and Their Structural Determinants.
Structure, 2017
4Z3C
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ZINC FINGER REGION OF HUMAN TET3 IN COMPLEX WITH CPG DNA
分子名称:DNA (5'-D(*GP*CP*CP*AP*AP*CP*GP*TP*TP*GP*GP*C)-3'), Methylcytosine dioxygenase, UNKNOWN ATOM OR ION, ...
著者Liu, K., Xu, C., Tempel, W., Dong, A., Arrowsmith, C.H., Bountra, C., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
登録日2015-03-31
公開日2015-04-29
最終更新日2018-01-03
実験手法X-RAY DIFFRACTION (1.57 Å)
主引用文献DNA Sequence Recognition of Human CXXC Domains and Their Structural Determinants.
Structure, 2017
5VC9
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ZINC FINGER OF HUMAN CXXC4 IN COMPLEX WITH CPG DNA
分子名称:CpG DNA, CXXC-type zinc finger protein 4, UNKNOWN ATOM OR ION, ...
著者Liu, K., Xu, C., Tempel, W., Walker, J.R., Arrowsmith, C.H., Bountra, C., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
登録日2017-03-31
公開日2017-06-28
最終更新日2018-01-10
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献DNA Sequence Recognition of Human CXXC Domains and Their Structural Determinants.
Structure, 26, 2018
5W9Q
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ZINC FINGER REGION OF MBD1 IN COMPLEX WITH CPG DNA
分子名称:Methyl-CpG-binding domain protein 1, dna, ZINC ION, ...
著者Liu, K., Xu, C., Tempel, W., Walker, J.R., Arrowsmith, C.H., Bountra, C., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
登録日2017-06-23
公開日2017-10-18
最終更新日2018-01-10
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献DNA Sequence Recognition of Human CXXC Domains and Their Structural Determinants.
Structure, 26, 2018
5W9S
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ZINC FINGER OF HUMAN CXXC5 IN COMPLEX WITH CPG DNA
分子名称:CpG DNA fragment, CXXC-type zinc finger protein 5, ZINC ION, ...
著者Liu, K., Xu, C., Tempel, W., Walker, J.R., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
登録日2017-06-23
公開日2017-10-18
最終更新日2018-01-10
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献DNA Sequence Recognition of Human CXXC Domains and Their Structural Determinants.
Structure, 26, 2018
6ASB
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CXXC AND PHD-TYPE ZINC FINGER REGIONS OF FBXL19 IN COMPLEX WITH DNA
分子名称:DNA (5'-D(*GP*CP*CP*AP*AP*CP*GP*TP*TP*GP*GP*C)-3'), F-box/LRR-repeat protein 19, ZINC ION
著者Liu, K., Tempel, W., Walker, J.R., Arrowsmith, C.H., Bountra, C., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
登録日2017-08-24
公開日2017-10-18
最終更新日2018-01-10
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献DNA Sequence Recognition of Human CXXC Domains and Their Structural Determinants.
Structure, 26, 2018
6ASD
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ZINC FINGER REGION OF HUMAN TET1 IN COMPLEX WITH CPG DNA
分子名称:DNA (5'-D(*GP*CP*CP*AP*CP*CP*GP*GP*TP*GP*GP*C)-3'), Methylcytosine dioxygenase TET1, UNKNOWN ATOM OR ION, ...
著者Liu, K., Xu, C., Tempel, W., Walker, J.R., Arrowsmith, C.H., Bountra, C., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
登録日2017-08-24
公開日2017-10-18
最終更新日2018-01-10
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献DNA Sequence Recognition of Human CXXC Domains and Their Structural Determinants.
Structure, 26, 2018