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7ZYI
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BU of 7zyi by Molmil
Structure of the human sodium/bile acid cotransporter (NTCP) in complex with Fab and nanobody
Descriptor: CHOLESTEROL, GLYCOCHENODEOXYCHOLIC ACID, Nanobody, ...
Authors:Liu, H, Irobalieva, R.N, Bang-Sorensen, R, Nosol, K, Mukherjee, S, Agrawal, P, Stieger, B, Kossiakoff, A.A, Locher, K.P.
Deposit date:2022-05-24
Release date:2022-07-13
Last modified:2022-08-10
Method:ELECTRON MICROSCOPY (2.88 Å)
Cite:Structure of human NTCP reveals the basis of recognition and sodium-driven transport of bile salts into the liver.
Cell Res., 32, 2022
8A0S
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BU of 8a0s by Molmil
MTH1 in complex with TH013350
Descriptor: 4-[(2-chlorophenyl)methylsulfanyl]-5~{H}-pyrimidin-2-one, 7,8-dihydro-8-oxoguanine triphosphatase, SULFATE ION
Authors:Liu, H, Scaletti, E, Stenmark, P.
Deposit date:2022-05-30
Release date:2023-09-20
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:MTH1 in complex with TH013350
To Be Published
8RQF
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BU of 8rqf by Molmil
Cryo-EM structure of human NTCP-Bulevirtide complex
Descriptor: Fab-specific nanobody, Heavy chain of Fab3, Light chain of Fab3, ...
Authors:Liu, H, Zakrzewicz, D, Nosol, K, Irobalieva, R.N, Mukherjee, S, Bang-Soerensen, R, Goldmann, N, Kunz, S, Rossi, L, Kossiakoff, A.A, Urban, S, Glebe, D, Geyer, J, Locher, K.P.
Deposit date:2024-01-18
Release date:2024-03-27
Method:ELECTRON MICROSCOPY (3.41 Å)
Cite:Cryo-EM structure of human NTCP-Bulevirtide complex
To Be Published
8W89
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BU of 8w89 by Molmil
Cryo-EM structure of the PEA-bound TAAR1-Gs complex
Descriptor: 2-PHENYLETHYLAMINE, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Liu, H, Zheng, Y, Wang, Y, Wang, Y, He, X, Xu, P, Huang, S, Yuan, Q, Zhang, X, Wang, S, Xu, H.E, Xu, F.
Deposit date:2023-09-01
Release date:2023-11-22
Last modified:2024-01-03
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Recognition of methamphetamine and other amines by trace amine receptor TAAR1.
Nature, 624, 2023
8W87
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BU of 8w87 by Molmil
Cryo-EM structure of the METH-TAAR1 complex
Descriptor: (2S)-N-methyl-1-phenylpropan-2-amine, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Liu, H, Zheng, Y, Wang, Y, Wang, Y, He, X, Xu, P, Huang, S, Yuan, Q, Zhang, X, Wang, S, Xu, H.E, Xu, F.
Deposit date:2023-09-01
Release date:2023-11-22
Last modified:2024-01-03
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Recognition of methamphetamine and other amines by trace amine receptor TAAR1.
Nature, 624, 2023
8W8A
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BU of 8w8a by Molmil
Cryo-EM structure of the RO5256390-TAAR1 complex
Descriptor: (4S)-4-[(2S)-2-phenylbutyl]-1,3-oxazolidin-2-imine, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Liu, H, Zheng, Y, Wang, Y, Wang, Y, He, X, Xu, P, Huang, S, Yuan, Q, Zhang, X, Wang, S, Xu, H.E, Xu, F.
Deposit date:2023-09-01
Release date:2023-11-22
Last modified:2024-01-03
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Recognition of methamphetamine and other amines by trace amine receptor TAAR1.
Nature, 624, 2023
8W88
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BU of 8w88 by Molmil
Cryo-EM structure of the SEP363856-bound TAAR1-Gs complex
Descriptor: 1-[(7~{S})-5,7-dihydro-4~{H}-thieno[2,3-c]pyran-7-yl]-~{N}-methyl-methanamine, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Liu, H, Zheng, Y, Wang, Y, Wang, Y, He, X, Xu, P, Huang, S, Yuan, Q, Zhang, X, Wang, S, Xu, H.E, Xu, F.
Deposit date:2023-09-01
Release date:2023-11-22
Last modified:2024-01-03
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Recognition of methamphetamine and other amines by trace amine receptor TAAR1.
Nature, 624, 2023
8W8B
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BU of 8w8b by Molmil
Cryo-EM structure of SEP-363856 bounded serotonin 1A (5-HT1A) receptor-Gi protein complex
Descriptor: 1-[(7~{S})-5,7-dihydro-4~{H}-thieno[2,3-c]pyran-7-yl]-~{N}-methyl-methanamine, Antibody fragment scFv16, CHOLESTEROL, ...
Authors:Liu, H, Zheng, Y, Wang, Y, Wang, Y, He, X, Xu, P, Huang, S, Yuan, Q, Zhang, X, Wang, S, Xu, H.E, Xu, F.
Deposit date:2023-09-01
Release date:2023-11-22
Last modified:2024-01-03
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Recognition of methamphetamine and other amines by trace amine receptor TAAR1.
Nature, 624, 2023
7NA8
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BU of 7na8 by Molmil
Structures of human ghrelin receptor-Gi complexes with ghrelin and a synthetic agonist
Descriptor: 1-(methanesulfonyl)-1'-(2-methyl-L-alanyl-O-benzyl-D-seryl)-1,2-dihydrospiro[indole-3,4'-piperidine], Antibody fragment, CHOLESTEROL, ...
Authors:Liu, H, Sun, D, Sun, J, Zhang, C.
Deposit date:2021-06-20
Release date:2021-12-15
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Structural basis of human ghrelin receptor signaling by ghrelin and the synthetic agonist ibutamoren
Nat Commun, 12, 2021
7NA7
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BU of 7na7 by Molmil
Structures of human ghrelin receptor-Gi complexes with ghrelin and a synthetic agonist
Descriptor: Antibody fragment, CHOLESTEROL, Ghrelin-27, ...
Authors:Liu, H, Sun, D, Sun, J, Zhang, C.
Deposit date:2021-06-20
Release date:2021-12-15
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Structural basis of human ghrelin receptor signaling by ghrelin and the synthetic agonist ibutamoren
Nat Commun, 12, 2021
7LM8
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BU of 7lm8 by Molmil
Crystal structure of SARS-CoV-2 spike protein receptor-binding domain in complex with two cross-neutralizing antibodies CV38-142 and COVA1-16 Fabs isolated from COVID-19 patients
Descriptor: 1,2-ETHANEDIOL, COVA1-16 Fab heavy chain, COVA1-16 Fab light chain, ...
Authors:Liu, H, Wilson, I.A.
Deposit date:2021-02-05
Release date:2021-03-31
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.936 Å)
Cite:A combination of cross-neutralizing antibodies synergizes to prevent SARS-CoV-2 and SARS-CoV pseudovirus infection.
Cell Host Microbe, 29, 2021
7LM9
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BU of 7lm9 by Molmil
Crystal structure of SARS-CoV spike protein receptor-binding domain in complex with a cross-neutralizing antibody CV38-142 Fab isolated from COVID-19 patient
Descriptor: 1,2-ETHANEDIOL, CV38-142 Fab heavy chain, CV38-142 Fab light chain, ...
Authors:Liu, H, Yuan, M, Zhu, X, Wilson, I.A.
Deposit date:2021-02-05
Release date:2021-03-31
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:A combination of cross-neutralizing antibodies synergizes to prevent SARS-CoV-2 and SARS-CoV pseudovirus infection.
Cell Host Microbe, 29, 2021
7T5I
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BU of 7t5i by Molmil
Crystal Structure of Strictosidine Synthase in complex with R-IPA(2-(1H-indol-3-yl) propan-1-amine)
Descriptor: (2R)-2-(1H-indol-3-yl)propan-1-amine, Strictosidine synthase
Authors:Liu, H, Panjikar, S, Futamura, Y, Shao, N, Osada, H, Zou, H.
Deposit date:2021-12-12
Release date:2022-12-14
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.94 Å)
Cite:Beta-Branched Tryptamine Provoked Non Sandwich-Like-Mode Catalysis of Strictosidine Synthase to Antimalarial Indole Alkaloids
to be published
7T5J
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BU of 7t5j by Molmil
Crystal Structure of Strictosidine Synthase in complex with S-IPA (2-(1H-indol-3-yl) propan-1-amine)
Descriptor: (2S)-2-(1H-indol-3-yl)propan-1-amine, Strictosidine synthase
Authors:Liu, H, Panjikar, S, Futamura, Y, Shao, N, Osada, H, Zou, H.
Deposit date:2021-12-12
Release date:2022-12-14
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.86 Å)
Cite:beta-Branched Tryptamine Provoked Non Sandwich-Like-Mode Catalysis of Strictosidine Synthase to Antimalarial Indole Alkaloids
to be published
8Y6B
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BU of 8y6b by Molmil
Structure of human LGI1-ADAM22 complex in space group P212121
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Disintegrin and metalloproteinase domain-containing protein 22, ...
Authors:Liu, H, Xu, F.
Deposit date:2024-02-02
Release date:2024-02-14
Method:X-RAY DIFFRACTION (3.49 Å)
Cite:Structure of human LGI1-ADAM22 complex in space group P212121
To Be Published
6C1R
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BU of 6c1r by Molmil
Crystal structure of human C5a receptor in complex with an orthosteric antagonist PMX53 and an allosteric antagonist avacopan
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, MALONATE ION, OLEIC ACID, ...
Authors:Liu, H, Wang, L, Wei, Z, Zhang, C.
Deposit date:2018-01-05
Release date:2018-05-30
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Orthosteric and allosteric action of the C5a receptor antagonists.
Nat. Struct. Mol. Biol., 25, 2018
6C1Q
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BU of 6c1q by Molmil
Crystal structure of human C5a receptor in complex with an orthosteric antagonist PMX53 and an allosteric antagonist NDT9513727
Descriptor: 1-(1,3-benzodioxol-5-yl)-~{N}-(1,3-benzodioxol-5-ylmethyl)-~{N}-[(3-butyl-2,5-diphenyl-imidazol-4-yl)methyl]methanamine, PMX53, Soluble cytochrome b562, ...
Authors:Liu, H, Wang, L, Wei, Z, Zhang, C.
Deposit date:2018-01-05
Release date:2018-05-30
Last modified:2020-01-08
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Orthosteric and allosteric action of the C5a receptor antagonists.
Nat. Struct. Mol. Biol., 25, 2018
8A3A
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BU of 8a3a by Molmil
MTH1 in complex with TH013074
Descriptor: 4-(4-methylphenyl)-1~{H}-quinazolin-2-one, 7,8-dihydro-8-oxoguanine triphosphatase, SULFATE ION
Authors:Liu, H, Scaletti, E, Stenmark, P.
Deposit date:2022-06-07
Release date:2023-09-20
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:MTH1 in complex with TH013074
To Be Published
8A34
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BU of 8a34 by Molmil
MTH1 in complex with TH013071
Descriptor: 5-(2-phenylphenyl)-1H-pyrimidine-2,4-dione, 7,8-dihydro-8-oxoguanine triphosphatase, ACETATE ION, ...
Authors:Liu, H, Scaletti, E, Stenmark, P.
Deposit date:2022-06-07
Release date:2023-09-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:MTH1 in complex with TH013071
To Be Published
4QSZ
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BU of 4qsz by Molmil
Crystal structure of mouse JMJd7 fused with maltose-binding protein
Descriptor: CITRATE ANION, Maltose-binding periplasmic protein, JmjC domain-containing protein 7 chimera, ...
Authors:Liu, H, Wang, C, Zhang, G.Y.
Deposit date:2014-07-06
Release date:2015-07-08
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.86 Å)
Cite:Crystal structure of mouse JMJd7 fused with maltose-binding protein
To be Published
4EXP
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BU of 4exp by Molmil
Structure of mouse Interleukin-34 in complex with mouse FMS
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-34, Macrophage colony-stimulating factor 1 receptor
Authors:Liu, H, Leo, C, Chen, X, Wong, B.R, Williams, L.T, Lin, H, He, X.
Deposit date:2012-04-30
Release date:2012-05-30
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The mechanism of shared but distinct CSF-1R signaling by the non-homologous cytokines IL-34 and CSF-1.
Biochim.Biophys.Acta, 1824, 2012
3CYV
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BU of 3cyv by Molmil
Crystal structure of uroporphyrinogen decarboxylase from Shigella flexineri: new insights into its catalytic mechanism
Descriptor: Uroporphyrinogen decarboxylase
Authors:Liu, H, Zhou, H, Bi, R.
Deposit date:2008-04-26
Release date:2009-04-28
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of uroporphyrinogen III decarboxylase from Shigella flexineri: new insights into its catalytic mechanism
To be Published
5ET0
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BU of 5et0 by Molmil
Crystal structure of Myo3b-ARB2 in complex with Espin1-AR
Descriptor: Espin, Myosin-IIIb
Authors:Liu, H, Li, J, Liu, W, Zhang, M.
Deposit date:2015-11-17
Release date:2016-02-03
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Myosin III-mediated cross-linking and stimulation of actin bundling activity of Espin
Elife, 5, 2016
5ET1
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BU of 5et1 by Molmil
Crystal structure of Myo3b-ARB1 in complex with Espin1-AR
Descriptor: Espin, GLYCEROL, Myosin-IIIb
Authors:Liu, H, Li, J, liu, W, Zhang, M.
Deposit date:2015-11-17
Release date:2016-02-03
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Myosin III-mediated cross-linking and stimulation of actin bundling activity of Espin
Elife, 5, 2016
1MY9
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BU of 1my9 by Molmil
Solution structure of a K+ cation stabilized dimeric RNA quadruplex containing two G:G(:A):G:G(:A) hexads, G:G:G:G tetrads and UUUU loops
Descriptor: 5'-R(*GP*GP*AP*GP*GP*UP*UP*UP*UP*GP*GP*AP*GP*G)-3'
Authors:Liu, H, Matsugami, A, Katahira, M, Uesugi, S.
Deposit date:2002-10-04
Release date:2003-10-07
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:A Dimeric RNA Quadruplex Architecture Comprised of Two G:G(:A):G:G(:A) Hexads, G:G:G:G Tetrads and UUUU Loops
J.Mol.Biol., 322, 2002

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PDB entries from 2024-03-27

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