Author results

5ZHP
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M3 MUSCARINIC ACETYLCHOLINE RECEPTOR IN COMPLEX WITH A SELECTIVE ANTAGONIST
分子名称:Muscarinic acetylcholine receptor M3,Endolysin,Endolysin,Muscarinic acetylcholine receptor M3, TETRAETHYLENE GLYCOL, MALTOSE, ...
著者Liu, H., Hofmann, J., Fish, I., Schaake, B., Eitel, K., Bartuschat, A., Kaindl, J., Rampp, H., Banerjee, A., Hubner, H., Clark, M.J., Vincent, S.G., Fisher, J., Heinrich, M., Hirata, K., Liu, X., Sunahara, R.K., Shoichet, B.K., Kobilka, B.K., Gmeiner, P.
登録日2018-03-13
公開日2018-11-28
最終更新日2018-12-05
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structure-guided development of selective M3 muscarinic acetylcholine receptor antagonists
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5ET0
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CRYSTAL STRUCTURE OF MYO3B-ARB2 IN COMPLEX WITH ESPIN1-AR
分子名称:Espin, Myosin-IIIb
著者Liu, H., Li, J., Liu, W., Zhang, M.
登録日2015-11-17
公開日2016-02-03
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Myosin III-mediated cross-linking and stimulation of actin bundling activity of Espin
Elife, 5, 2016
5ET1
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CRYSTAL STRUCTURE OF MYO3B-ARB1 IN COMPLEX WITH ESPIN1-AR
分子名称:Espin, Myosin-IIIb, GLYCEROL
著者Liu, H., Li, J., liu, W., Zhang, M.
登録日2015-11-17
公開日2016-02-03
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Myosin III-mediated cross-linking and stimulation of actin bundling activity of Espin
Elife, 5, 2016
3CYV
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CRYSTAL STRUCTURE OF UROPORPHYRINOGEN DECARBOXYLASE FROM SHIGELLA FLEXINERI: NEW INSIGHTS INTO ITS CATALYTIC MECHANISM
分子名称:Uroporphyrinogen decarboxylase
著者Liu, H., Zhou, H., Bi, R.
登録日2008-04-26
公開日2009-04-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of uroporphyrinogen III decarboxylase from Shigella flexineri: new insights into its catalytic mechanism
To be Published
4EXN
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CRYSTAL STRUCTURE OF MOUSE INTERLEUKIN-34
分子名称:Interleukin-34, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
著者Liu, H., Leo, C., Chen, X., Wong, B.R., Williams, L.T., Lin, H., He, X.
登録日2012-04-30
公開日2012-05-30
最終更新日2012-06-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The mechanism of shared but distinct CSF-1R signaling by the non-homologous cytokines IL-34 and CSF-1.
Biochim.Biophys.Acta, 1824, 2012
4EXP
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STRUCTURE OF MOUSE INTERLEUKIN-34 IN COMPLEX WITH MOUSE FMS
分子名称:Interleukin-34, Macrophage colony-stimulating factor 1 receptor, N-ACETYL-D-GLUCOSAMINE
著者Liu, H., Leo, C., Chen, X., Wong, B.R., Williams, L.T., Lin, H., He, X.
登録日2012-04-30
公開日2012-05-30
最終更新日2012-06-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The mechanism of shared but distinct CSF-1R signaling by the non-homologous cytokines IL-34 and CSF-1.
Biochim.Biophys.Acta, 1824, 2012
4FI1
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CRYSTAL STRUCTURE OF SCCK2 ALPHA IN COMPLEX WITH ATP
分子名称:Casein kinase II subunit alpha, MAGNESIUM ION, ADENOSINE-5'-TRIPHOSPHATE, ...
著者Liu, H., Wang, H., Teng, M., Li, X.
登録日2012-06-07
公開日2013-06-19
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Crystal structure of scCK2 alpha in complex with ATP
To be Published
4JQE
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CRYSTAL STRUCTURE OF SCCK2 ALPHA IN COMPLEX WITH AMPPN
分子名称:Casein kinase II subunit alpha, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
著者Liu, H.
登録日2013-03-20
公開日2014-03-05
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献The multiple nucleotide-divalent cation binding modes of Saccharomyces cerevisiae CK2 alpha indicate a possible co-substrate hydrolysis product (ADP/GDP) release pathway.
Acta Crystallogr.,Sect.D, 70, 2014
4JR7
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CRYSTAL STRUCTURE OF SCCK2 ALPHA IN COMPLEX WITH GMPPNP
分子名称:Casein kinase II subunit alpha, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, MAGNESIUM ION
著者Liu, H.
登録日2013-03-21
公開日2014-03-05
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献The multiple nucleotide-divalent cation binding modes of Saccharomyces cerevisiae CK2 alpha indicate a possible co-substrate hydrolysis product (ADP/GDP) release pathway.
Acta Crystallogr.,Sect.D, 70, 2014
4LFI
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CRYSTAL STRUCTURE OF SCCK2 ALPHA IN COMPLEX WITH GMPPNP
分子名称:Casein kinase II subunit alpha, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, MANGANESE (II) ION, ...
著者Liu, H.
登録日2013-06-27
公開日2014-03-05
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献The multiple nucleotide-divalent cation binding modes of Saccharomyces cerevisiae CK2 alpha indicate a possible co-substrate hydrolysis product (ADP/GDP) release pathway.
Acta Crystallogr.,Sect.D, 70, 2014
4MWH
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CRYSTAL STRUCTURE OF SCCK2 ALPHA IN COMPLEX WITH ATP
分子名称:Casein kinase II subunit alpha, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Liu, H.
登録日2013-09-24
公開日2013-11-20
最終更新日2014-03-05
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献The multiple nucleotide-divalent cation binding modes of Saccharomyces cerevisiae CK2 alpha indicate a possible co-substrate hydrolysis product (ADP/GDP) release pathway.
Acta Crystallogr.,Sect.D, 70, 2014
6C1Q
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CRYSTAL STRUCTURE OF HUMAN C5A RECEPTOR IN COMPLEX WITH AN ORTHOSTERIC ANTAGONIST PMX53 AND AN ALLOSTERIC ANTAGONIST NDT9513727
分子名称:Soluble cytochrome b562, C5a anaphylatoxin chemotactic receptor 1 chimera, PMX53, ...
著者Liu, H., Wang, L., Wei, Z., Zhang, C.
登録日2018-01-05
公開日2018-05-30
最終更新日2018-06-20
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Orthosteric and allosteric action of the C5a receptor antagonists.
Nat. Struct. Mol. Biol., 25, 2018
6C1R
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CRYSTAL STRUCTURE OF HUMAN C5A RECEPTOR IN COMPLEX WITH AN ORTHOSTERIC ANTAGONIST PMX53 AND AN ALLOSTERIC ANTAGONIST AVACOPAN
分子名称:Soluble cytochrome b562, C5a anaphylatoxin chemotactic receptor 1 chimera, PMX53, ...
著者Liu, H., Wang, L., Wei, Z., Zhang, C.
登録日2018-01-05
公開日2018-05-30
最終更新日2018-09-05
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Orthosteric and allosteric action of the C5a receptor antagonists.
Nat. Struct. Mol. Biol., 25, 2018
1MY9
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SOLUTION STRUCTURE OF A K+ CATION STABILIZED DIMERIC RNA QUADRUPLEX CONTAINING TWO G:G(:A):G:G(:A) HEXADS, G:G:G:G TETRADS AND UUUU LOOPS
分子名称:5'-R(*GP*GP*AP*GP*GP*UP*UP*UP*UP*GP*GP*AP*GP*G)-3'
著者Liu, H., Matsugami, A., Katahira, M., Uesugi, S.
登録日2002-10-04
公開日2003-10-07
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献A Dimeric RNA Quadruplex Architecture Comprised of Two G:G(:A):G:G(:A) Hexads, G:G:G:G Tetrads and UUUU Loops
J.Mol.Biol., 322, 2002
2JBM
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QPRTASE STRUCTURE FROM HUMAN
分子名称:NICOTINATE-NUCLEOTIDE PYROPHOSPHORYLASE, S,R MESO-TARTARIC ACID
著者Liu, H., Naismith, J.H.
登録日2006-12-08
公開日2007-11-13
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural and Kinetic Characterization of Quinolinate Phosphoribosyltransferase (Hqprtase) from Homo Sapiens.
J.Mol.Biol., 373, 2007
2O26
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STRUCTURE OF A CLASS III RTK SIGNALING ASSEMBLY
分子名称:Kit ligand, Mast/stem cell growth factor receptor, BETA-L-FUCOSE, ...
著者Liu, H., Chen, X., Focia, P.J., He, X.
登録日2006-11-29
公開日2007-03-13
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis for stem cell factor-KIT signaling and activation of class III receptor tyrosine kinases.
Embo J., 26, 2007
2O27
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STRUCTURE OF A CLASS III RTK SIGNALING ASSEMBLY
分子名称:Kit ligand
著者Liu, H., Chen, X., Focia, P., He, X.
登録日2006-11-29
公開日2007-03-13
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural basis for stem cell factor-KIT signaling and activation of class III receptor tyrosine kinases.
Embo J., 26, 2007
3G5C
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STRUCTURAL AND BIOCHEMICAL STUDIES ON THE ECTODOMAIN OF HUMAN ADAM22
分子名称:ADAM 22, N-ACETYL-D-GLUCOSAMINE, CALCIUM ION
著者Liu, H., Shim, A., Chen, X., He, X.
登録日2009-02-04
公開日2009-08-18
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献Structural and biochemical studies on the ectodomain of human ADAM22
J.Biol.Chem., 2009
3IZO
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MODEL OF THE FIBER TAIL AND ITS INTERACTIONS WITH THE PENTON BASE OF HUMAN ADENOVIRUS BY CRYO-ELECTRON MICROSCOPY
分子名称:Penton protein, Fiber
著者Liu, H.
登録日2010-11-05
公開日2011-01-05
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Model of the Trimeric Fiber and Its Interactions with the Pentameric Penton Base of Human Adenovirus by Cryo-electron Microscopy.
J.Mol.Biol., 406, 2011
3JA4
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RNA-DEPENDENT RNA POLYMERASES OF TRANSCRIBING CYPOVIRUSES
分子名称:RNA-dependent RNA polymerase
著者Liu, H., Cheng, L.
登録日2015-04-20
公開日2015-10-28
実験手法ELECTRON MICROSCOPY (4.8 Å)
主引用文献Cryo-EM shows the polymerase structures and a nonspooled genome within a dsRNA virus.
Science, 349, 2015
3JA5
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GENOME AND RDRP STRUCTURE WITHIN THE CAPSID OF NO-TRANSCRIBING CYPOVIRUS
分子名称:RNA-dependent RNA polymerase
著者Liu, H., Cheng, L.
登録日2015-04-21
公開日2015-10-28
最終更新日2018-06-20
実験手法ELECTRON MICROSCOPY (12 Å)
主引用文献Cryo-EM shows the polymerase structures and a nonspooled genome within a dsRNA virus.
Science, 349, 2015
3NVN
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MOLECULAR MECHANISM OF GUIDANCE CUE RECOGNITION
分子名称:EVM139, Plexin-C1, 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE, ...
著者Liu, H., Juo, Z., Shim, A., Focia, P., Chen, X., Garcia, C., He, X.
登録日2010-07-08
公開日2010-09-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Structural Basis of Semaphorin-Plexin Recognition and Viral Mimicry from Sema7A and A39R Complexes with PlexinC1.
Cell(Cambridge,Mass.), 142, 2010
3NVX
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MOLECULAR MECHANISM OF GUIDANCE CUE RECOGNITION
分子名称:Protein A39, N-ACETYL-D-GLUCOSAMINE
著者Liu, H., Juo, Z., Shim, A., Focia, P., Chen, X., Garcia, C., He, X.
登録日2010-07-08
公開日2010-09-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Basis of Semaphorin-Plexin Recognition and Viral Mimicry from Sema7A and A39R Complexes with PlexinC1.
Cell(Cambridge,Mass.), 142, 2010
3P3Y
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CRYSTAL STRUCTURE OF NEUROFASCIN HOMOPHILIC ADHESION COMPLEX IN SPACE GROUP P6522
分子名称:Neurofascin, N-ACETYL-D-GLUCOSAMINE
著者Liu, H., He, X.
登録日2010-10-05
公開日2010-11-03
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Homophilic adhesion mechanism of neurofascin, a member of the l1 family of neural cell adhesion molecules.
J.Biol.Chem., 286, 2011
3P40
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CRYSTAL STRUCTURE OF NEUROFASCIN ADHESION COMPLEX IN SPACE GROUP P3221
分子名称:Neurofascin, N-ACETYL-D-GLUCOSAMINE
著者Liu, H., He, X.
登録日2010-10-05
公開日2010-11-03
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Homophilic adhesion mechanism of neurofascin, a member of the l1 family of neural cell adhesion molecules.
J.Biol.Chem., 286, 2011