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3DHA
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AN ULTRAL HIGH RESOLUTION STRUCTURE OF N-ACYL HOMOSERINE LACTONE HYDROLASE WITH THE PRODUCT N-HEXANOYL-L-HOMOSERINE BOUND AT AN ALTERNATIVE SITE
分子名称:N-Acyl Homoserine Lactone Hydrolase, ZINC ION, N-hexanoyl-L-homoserine, ...
著者Liu, D., Momb, J., Thomas, P.W., Moulin, A., Petsko, G.A., Fast, W., Ringe, D.
登録日2008-06-17
公開日2008-07-29
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (0.95 Å)
主引用文献Mechanism of the quorum-quenching lactonase (AiiA) from Bacillus thuringiensis. 1. Product-bound structures.
Biochemistry, 47, 2008
3DHB
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1.4 ANGSTROM STRUCTURE OF N-ACYL HOMOSERINE LACTONE HYDROLASE WITH THE PRODUCT N-HEXANOYL-L-HOMOSERINE BOUND AT THE CATALYTIC METAL CENTER
分子名称:N-Acyl Homoserine Lactone Hydrolase, ZINC ION, N-hexanoyl-L-homoserine, ...
著者Liu, D., Momb, J., Thomas, P.W., Moulin, A., Petsko, G.A., Fast, W., Ringe, D.
登録日2008-06-17
公開日2008-07-29
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Mechanism of the quorum-quenching lactonase (AiiA) from Bacillus thuringiensis. 1. Product-bound structures.
Biochemistry, 47, 2008
3DHC
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1.3 ANGSTROM STRUCTURE OF N-ACYL HOMOSERINE LACTONE HYDROLASE WITH THE PRODUCT N-HEXANOYL-L-HOMOCYSTEINE BOUND TO THE CATALYTIC METAL CENTER
分子名称:N-Acyl Homoserine Lactone Hydrolase, ZINC ION, N-hexanoyl-L-homocysteine, ...
著者Liu, D., Momb, J., Thomas, P.W., Moulin, A., Petsko, G.A., Fast, W., Ringe, D.
登録日2008-06-17
公開日2008-07-29
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Mechanism of the quorum-quenching lactonase (AiiA) from Bacillus thuringiensis. 1. Product-bound structures.
Biochemistry, 47, 2008
2A7M
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1.6 ANGSTROM RESOLUTION STRUCTURE OF THE QUORUM-QUENCHING N-ACYL HOMOSERINE LACTONE HYDROLASE OF BACILLUS THURINGIENSIS
分子名称:N-acyl homoserine lactone hydrolase, ZINC ION, GLYCEROL
著者Liu, D., Lepore, B.W., Petsko, G.A., Thomas, P.W., Stone, E.M., Fast, W., Ringe, D.
登録日2005-07-05
公開日2005-08-16
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Three-dimensional structure of the quorum-quenching N-acyl homoserine lactone hydrolase from Bacillus thuringiensis
Proc.Natl.Acad.Sci.Usa, 102, 2005
2Q7W
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STRUCTURAL STUDIES REVEALS THE INACTIVATION OF E. COLI L-ASPARTATE AMINOTRANSFERASE (S)-4,5-AMINO-DIHYDRO-2-THIOPHENECARBOXYLIC ACID (SADTA) VIA TWO MECHANISMS AT PH 6.0
分子名称:Aspartate aminotransferase, SULFATE ION, 4-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]THIOPHENE-2-CARBOXYLIC ACID, ...
著者Liu, D., Pozharski, E., Lepore, B., Fu, M., Silverman, R.B., Petsko, G.A., Ringe, D.
登録日2007-06-07
公開日2007-09-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Inactivation of Escherichia coli l-Aspartate Aminotransferase by (S)-4-Amino-4,5-dihydro-2-thiophenecarboxylic Acid Reveals "A Tale of Two Mechanisms".
Biochemistry, 46, 2007
2QA3
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STRUCTURAL STUDIES REVEAL THE INACTIVATION OF E. COLI L-ASPARTATE AMINOTRANSFERASE BY (S)-4,5-AMINO-DIHYDRO-2-THIOPHENECARBOXYLIC ACID (SADTA) VIA TWO MECHANISMS (AT PH6.5)
分子名称:Aspartate aminotransferase, SULFATE ION, 4-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]THIOPHENE-2-CARBOXYLIC ACID, ...
著者Liu, D., Pozharski, E., Lepore, B., Fu, M., Silverman, R.B., Petsko, G.A., Ringe, D.
登録日2007-06-14
公開日2007-12-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Inactivation of Escherichia coli L-aspartate aminotransferase by (S)-4-amino-4,5-dihydro-2-thiophenecarboxylic acid reveals "a tale of two mechanisms".
Biochemistry, 46, 2007
2QB2
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STRUCTURAL STUDIES REVEAL THE INACTIVATION OF E. COLI L-ASPARTATE AMINOTRANSFERASE BY (S)-4,5-DIHYDRO-2THIOPHENECARBOYLIC ACID (SADTA) VIA TWO MECHANISMS (AT PH 7.0).
分子名称:Aspartate aminotransferase, SULFATE ION, 4-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]THIOPHENE-2-CARBOXYLIC ACID, ...
著者Liu, D., Pozharski, E., Lepore, B., Fu, M., Silverman, R.B., Petsko, G.A., Ringe, D.
登録日2007-06-15
公開日2007-12-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Inactivation of Escherichia coli L-aspartate aminotransferase by (S)-4-amino-4,5-dihydro-2-thiophenecarboxylic acid reveals "a tale of two mechanisms".
Biochemistry, 46, 2007
2QB3
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STRUCTURAL STUDIES REVEAL THE INACTIVATION OF E. COLI L-ASPARTATE AMINOTRANSFERASE BY (S)-4,5-DIHYDRO-2-THIOPHENECARBOXYLIC ACID (SADTA) VIA TWO MECHANISMS (AT PH 7.5)
分子名称:Aspartate aminotransferase, SULFATE ION, 4-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]THIOPHENE-2-CARBOXYLIC ACID, ...
著者Liu, D., Pozharski, E., Lepore, B., Fu, M., Silverman, R.B., Petsko, G.A., Ringe, D.
登録日2007-06-15
公開日2007-12-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Inactivation of Escherichia coli L-aspartate aminotransferase by (S)-4-amino-4,5-dihydro-2-thiophenecarboxylic acid reveals "a tale of two mechanisms".
Biochemistry, 46, 2007
2QBT
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STRUCTURAL STUDIES REVEAL THE INACTIVATION OF E. COLI L-ASPARTATE AMINOTRANSFERASE BY (S)-4,5-AMINO-DIHYDRO-2-THIOPHENECARBOXYLIC ACID (SADTA) VIA TWO MECHANISMS (AT PH 8.0)
分子名称:Aspartate aminotransferase, SULFATE ION, 4-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]THIOPHENE-2-CARBOXYLIC ACID, ...
著者Liu, D., Pozharski, E., Lepore, B., Fu, M., Silverman, R.B., Petsko, G.A., Ringe, D.
登録日2007-06-18
公開日2007-09-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Inactivation of Escherichia coli l-Aspartate Aminotransferase by (S)-4-Amino-4,5-dihydro-2-thiophenecarboxylic Acid Reveals "A Tale of Two Mechanisms".
Biochemistry, 46, 2007
2R2D
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STRUCTURE OF A QUORUM-QUENCHING LACTONASE (AIIB) FROM AGROBACTERIUM TUMEFACIENS
分子名称:Zn-dependent hydrolases, ZINC ION, PHOSPHATE ION, ...
著者Liu, D., Thomas, P.W., Momb, J., Hoang, Q., Petsko, G.A., Ringe, D., Fast, W.
登録日2007-08-24
公開日2007-10-09
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structure and specificity of a quorum-quenching lactonase (AiiB) from Agrobacterium tumefaciens.
Biochemistry, 46, 2007
3EAC
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CRYSTAL STRUCTURE OF SH2 DOMAIN OF HUMAN CSK (CARBOXYL-TERMINAL SRC KINASE), OXIDIZED FORM.
分子名称:Tyrosine-protein kinase CSK
著者Liu, D., Seidel, R.D., Cowburn, D.
登録日2008-08-25
公開日2009-11-10
最終更新日2016-12-14
実験手法X-RAY DIFFRACTION (1.37 Å)
主引用文献Combining biophysical methods to analyze the disulfide bond in SH2 domain of C-terminal Src kinase.
Biophys Rep, 2, 2016
3EAZ
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CRYSTAL STRUCTURE OF SH2 DOMAIN OF HUMAN CSK (CARBOXYL-TERMINAL SRC KINASE), C122S MUTANT.
分子名称:Tyrosine-protein kinase CSK
著者Liu, D., Seidel, R.D., Cowburn, D.
登録日2008-08-26
公開日2009-11-10
最終更新日2016-12-14
実験手法X-RAY DIFFRACTION (1.31 Å)
主引用文献Combining biophysical methods to analyze the disulfide bond in SH2 domain of C-terminal Src kinase.
Biophys Rep, 2, 2016
3PA9
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MECHANISM OF INACTIVATION OF E. COLI ASPARTATE AMINOTRANSFERASE BY (S)-4-AMINO-4,5-DIHYDRO-2-FURANCARBOXYLIC ACID (S-ADFA) PH 7.5
分子名称:Aspartate aminotransferase, 4-aminofuran-2-carboxylic acid, 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, ...
著者Liu, D., Pozharski, E., Fu, M., Silverman, R.B., Ringe, D.
登録日2010-10-19
公開日2010-12-01
最終更新日2019-07-17
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Mechanism of inactivation of Escherichia coli aspartate aminotransferase by (S)-4-amino-4,5-dihydro-2-furancarboxylic acid .
Biochemistry, 49, 2010
3PAA
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MECHANISM OF INACTIVATION OF E. COLI ASPARTATE AMINOTRANSFERASE BY (S)-4-AMINO-4,5-DIHYDRO-2-FURANCARBOXYLIC ACID (S-ADFA) PH 8.0
分子名称:Aspartate aminotransferase, 4-aminofuran-2-carboxylic acid, 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, ...
著者Liu, D., Pozharski, E., Fu, M., Silverman, R.B., Ringe, D.
登録日2010-10-19
公開日2010-12-01
最終更新日2019-07-17
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Mechanism of inactivation of Escherichia coli aspartate aminotransferase by (S)-4-amino-4,5-dihydro-2-furancarboxylic acid .
Biochemistry, 49, 2010
1A4O
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14-3-3 PROTEIN ZETA ISOFORM
分子名称:14-3-3 PROTEIN ZETA
著者Liu, D., Bienkowska, J., Petosa, C., Collier, R.J., Fu, H., Liddington, R.C.
登録日1998-02-01
公開日1999-03-02
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of the zeta isoform of the 14-3-3 protein.
Nature, 376, 1995
1JR6
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SOLUTION STRUCTURE OF AN ENGINEERED ARGININE-RICH SUBDOMAIN 2 OF THE HEPATITIS C VIRUS NS3 RNA HELICASE
分子名称:Helicase NS3
著者Liu, D., Wyss, D.F., Wang, Y.S., Gesell, J.J.
登録日2001-08-10
公開日2002-08-10
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Solution structure and backbone dynamics of an engineered arginine-rich subdomain 2 of the hepatitis C virus NS3 RNA helicase.
J.Mol.Biol., 314, 2001
1ONB
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SOLUTION STRUCTURE OF AN ENGINEERED ARGININE-RICH SUBDOMAIN 2 OF THE HEPATITIS C VIRUS NS3 RNA HELICASE
分子名称:helicase NS3
著者Liu, D., Wang, Y.S., Gesell, J.J., Wyss, D.F.
登録日2003-02-27
公開日2003-03-11
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Solution structure and backbone dynamics of an engineered arginine-rich subdomain 2 of the hepatitis C virus NS3 RNA helicase
J.Mol.Biol., 314, 2001
1OVQ
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SOLUTION STRUCTURE OF THE HYPOTHETICAL PROTEIN YQGF FROM ESCHERICHIA COLI
分子名称:Hypothetical protein yqgF
著者Liu, D., Wang, Y.S., Wyss, D.F.
登録日2003-03-27
公開日2003-11-04
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Solution structure of the hypothetical protein YqgF from Escherichia coli reveals an RNAse H fold.
J.Biomol.NMR, 27, 2003
1RQ8
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SOLUTION STRUCTURE OF THE HYPOTHETICAL PROTEIN SAV1595 FROM STAPHYLOCOCCUS AUREUS, A PUTATIVE RNA BINDING PROTEIN
分子名称:conserved hypothetical protein
著者Liu, D., Wyss, D.F.
登録日2003-12-04
公開日2004-07-06
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Solution Structure of the Hypothetical Protein SAV1595 from Staphylococcus Aureus, a Putative RNA Binding Protein.
J.Biomol.Nmr, 29, 2004
1TBA
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SOLUTION STRUCTURE OF A TBP-TAFII230 COMPLEX: PROTEIN MIMICRY OF THE MINOR GROOVE SURFACE OF THE TATA BOX UNWOUND BY TBP, NMR, 25 STRUCTURES
分子名称:TRANSCRIPTION INITIATION FACTOR IID 230K CHAIN, TRANSCRIPTION INITIATION FACTOR TFIID
著者Liu, D., Ishima, R., Tong, K.I., Bagby, S., Kokubo, T., Muhandiram, D.R., Kay, L.E., Nakatani, Y., Ikura, M.
登録日1998-08-16
公開日1999-08-16
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Solution structure of a TBP-TAF(II)230 complex: protein mimicry of the minor groove surface of the TATA box unwound by TBP.
Cell(Cambridge,Mass.), 94, 1998
2LSI
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SOLUTION STRUCTURE OF POLYMERASE-INTERACTING DOMAIN OF HUMAN REV1 IN COMPLEX WITH TRANSLESIONAL SYNTHESIS POLYMERASE KAPPA
分子名称:DNA repair protein REV1, DNA polymerase kappa
著者Liu, D., Ryu, K., Ko, J., Choi, B.
登録日2012-05-01
公開日2013-05-29
実験手法SOLUTION NMR
主引用文献Insights into the scaffold mechanism of human Rev1 in translesional synthesis revealed by the structural studies on its polymerase-interacting domain
To be Published
4FZ3
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CRYSTAL STRUCTURE OF SIRT3 IN COMPLEX WITH ACETYL P53 PEPTIDE COUPLED WITH 4-AMINO-7-METHYLCOUMARIN
分子名称:NAD-dependent protein deacetylase sirtuin-3, mitochondrial, peptide from Cellular tumor antigen p53, ...
著者Liu, D., Wu, J., Zhang, D., Chen, K., Jiang, H., Liu, H.
登録日2012-07-06
公開日2013-03-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Discovery and Mechanism Study of SIRT1 Activators that Promote the Deacetylation of Fluorophore-Labeled Substrate
J.Med.Chem., 56, 2013
2F3V
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SOLUTION STRUCTURE OF 1-110 FRAGMENT OF STAPHYLOCOCCAL NUCLEASE WITH V66W MUTATION
分子名称:Thermonuclease
著者Liu, D., Xie, T., Feng, Y., Shan, L., Ye, K., Wang, J.
登録日2005-11-22
公開日2006-12-05
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Folding stability and cooperativity of the three forms of 1-110 residues fragment of staphylococcal nuclease
Biophys.J., 92, 2007
2F3W
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SOLUTION STRUCTURE OF 1-110 FRAGMENT OF STAPHYLOCOCCAL NUCLEASE IN 2M TMAO
分子名称:Thermonuclease
著者Liu, D., Xie, T., Feng, Y., Shan, L., Ye, K., Wang, J.
登録日2005-11-22
公開日2006-12-05
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Folding stability and cooperativity of the three forms of 1-110 residues fragment of staphylococcal nuclease
Biophys.J., 92, 2007
6E5X
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CRYSTAL STRUCTURE OF EBOLA VIRUS VP30 C-TERMINUS/RBBP6 PEPTIDE COMPLEX
分子名称:Minor nucleoprotein VP30, E3 ubiquitin-protein ligase RBBP6, CALCIUM ION
著者Liu, D., Small, G.I., Leung, D.W., Amarasinghe, G.K.
登録日2018-07-23
公開日2018-12-12
最終更新日2019-02-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Protein Interaction Mapping Identifies RBBP6 as a Negative Regulator of Ebola Virus Replication.
Cell, 175, 2018