Author results

5CO5
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CRYSTAL STRUCTURE OF AC-ACHBP IN COMPLEX WITH CONOTOXIN GIC
分子名称:Soluble acetylcholine receptor, Alpha-conotoxin GIC
著者Wang, X.Q., Xu, M.Y., Luo, S.L., Lin, B.
登録日2015-07-19
公開日2016-07-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of Ac-AChBP in complex with conotoxin GIC
To Be Published
5IPI
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STRUCTURE OF ADENO-ASSOCIATED VIRUS TYPE 2 VLP
分子名称:Capsid protein VP1
著者Drouin, L.M., Lins, B., Janssen, M.E., Bennet, A., Chipman, P., McKenna, R., Chen, W., Muzyczka, N., Cardone, G., Baker, T.S., Agbandje-McKenna, M.
登録日2016-03-09
公開日2016-07-20
最終更新日2019-12-04
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Cryo-electron Microscopy Reconstruction and Stability Studies of the Wild Type and the R432A Variant of Adeno-associated Virus Type 2 Reveal that Capsid Structural Stability Is a Major Factor in Genome Packaging.
J.Virol., 90, 2016
5IPK
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STRUCTURE OF THE R432A VARIANT OF ADENO-ASSOCIATED VIRUS TYPE 2 VLP
分子名称:Capsid protein VP1
著者Drouin, L.M., Lins, B., Janssen, M.E., Bennet, A., Chipman, P., McKenna, R., Chen, W., Muzyczka, N., Cardone, G., Baker, T.S., Agbandje-McKenna, M.
登録日2016-03-09
公開日2016-07-20
最終更新日2019-12-04
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Cryo-electron Microscopy Reconstruction and Stability Studies of the Wild Type and the R432A Variant of Adeno-associated Virus Type 2 Reveal that Capsid Structural Stability Is a Major Factor in Genome Packaging.
J.Virol., 90, 2016
6MPG
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CRYO-EM STRUCTURE AT 3.2 A RESOLUTION OF HIV-1 FUSION PEPTIDE-DIRECTED ANTIBODY, A12V163-B.01, ELICITED BY VACCINATION OF RHESUS MACAQUES, IN COMPLEX WITH STABILIZED HIV-1 ENV BG505 DS-SOSIP, WHICH WAS ALSO BOUND TO ANTIBODIES VRC03 AND PGT122
分子名称:A12V163-b.01 Light Chain, Envelope glycoprotein gp41, Envelope glycoprotein gp120, ...
著者Acharya, P., Kwong, P.D.
登録日2018-10-06
公開日2019-07-24
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.
Cell, 178, 2019
6MPH
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CRYO-EM STRUCTURE AT 3.8 A RESOLUTION OF HIV-1 FUSION PEPTIDE-DIRECTED ANTIBODY, DF1W-A.01, ELICITED BY VACCINATION OF RHESUS MACAQUES, IN COMPLEX WITH STABILIZED HIV-1 ENV BG505 DS-SOSIP, WHICH WAS ALSO BOUND TO ANTIBODIES VRC03 AND PGT122
分子名称:DF1W-a.01 heavy chain, DF1W-a.01 Light chain, Envelope glycoprotein gp41, ...
著者Acharya, P., Xu, K., Kwong, P.D.
登録日2018-10-06
公開日2019-07-24
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.
Cell, 178, 2019
6MQC
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VACCINE-ELICITED NHP FP-TARGETING NEUTRALIZING ANTIBODY 0PV-C.01 IN COMPLEX WITH FP (RESIDUE 512-519)
分子名称:0PV-C.01 antibody Fab heavy chain, 0PV-C.01 antibody Fab light chain, HIV fusion peptide residue 512-519
著者Xu, K., Wang, Y., Kwong, P.D.
登録日2018-10-09
公開日2019-07-31
最終更新日2019-11-13
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.
Cell, 178, 2019
6MQE
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VACCINE-ELICITED NHP FP-TARGETING HIV NEUTRALIZING ANTIBODY DFPH-A.15 IN COMPLEX WITH HIV FUSION PEPTIDE (RESIDUE 512-519)
分子名称:DFPHa.15 antibody Fab light chain, DFPHa.15 antibody Fab heavy chain, HIV fusion peptide
著者Xu, K., Wang, Y., Kwong, P.D.
登録日2018-10-09
公開日2019-07-31
最終更新日2019-11-13
実験手法X-RAY DIFFRACTION (2.459 Å)
主引用文献Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.
Cell, 178, 2019
6MQM
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VACCINE-ELICITED NHP FP-TARGETING NEUTRALIZING ANTIBODY DF1W-A.01 IN COMPLEX WITH HIV FUSION PEPTIDE (RESIDUE 512-519)
分子名称:antibody Fab heavy chain, antibody Fab light chain, HIV Env fusion peptide residue 512-519
著者Xu, K., Wang, Y., Kwong, P.D.
登録日2018-10-10
公開日2019-07-31
最終更新日2019-11-13
実験手法X-RAY DIFFRACTION (3.484 Å)
主引用文献Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.
Cell, 178, 2019
6MQR
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VACCINE-ELICITED NHP FP-TARGETING NEUTRALIZING ANTIBODY 0PV-A.01 IN COMPLEX WITH FP (RESIDUE 512-519)
分子名称:antibody 0PV-A.01 Fab heavy chain, antibody 0PV-A.01 Fab light chain, HIV fusion peptide residue 512-519, ...
著者Xu, K., Wang, Y., Kwong, P.D.
登録日2018-10-10
公開日2019-07-31
最終更新日2019-11-13
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.
Cell, 178, 2019
6MQS
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VACCINE-ELICITED NHP FP-TARGETING HIV NEUTRALIZING ANTIBODY A12V163-A.01 IN COMPLEX WITH HIV FUSION PEPTIDE (RESIDUE 512-519)
分子名称:antibody A12V163-a.01 heavy chain, antibody A12V163-a.01 light chain, HIV fusion peptide residue 512-519
著者Xu, K., Wang, Y., Kwong, P.D.
登録日2018-10-10
公開日2019-07-31
最終更新日2019-11-13
実験手法X-RAY DIFFRACTION (2.997 Å)
主引用文献Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.
Cell, 178, 2019
6N16
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VACCINE-ELICITED NHP FP-TARGETING NEUTRALIZING ANTIBODY 0PV-B.01 IN COMPLEX WITH HIV FUSION PEPTIDE (RESIDUE 512-519)
分子名称:antibody 0PV-b.01 Fab heavy chain, antibody 0PV-b.01 Fab light chain, HIV fusion peptide (512-519)
著者Xu, K., Wang, Y., Kwong, P.D.
登録日2018-11-08
公開日2019-07-31
最終更新日2019-11-13
実験手法X-RAY DIFFRACTION (2.302 Å)
主引用文献Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.
Cell, 178, 2019
6N1V
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CRYO-EM STRUCTURE AT 4.0 A RESOLUTION OF VACCINE-ELICITED ANTIBODY A12V163-A.01 IN COMPLEX WITH HIV-1 ENV BG505 DS-SOSIP, AND ANTIBODIES VRC03 AND PGT122
分子名称:A12V163-a.01 Heavy chain, A12V163-a.01 Light chain, Envelope glycoprotein gp120, ...
著者Acharya, P., Kwong, P.D.
登録日2018-11-12
公開日2019-07-24
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.
Cell, 178, 2019
6N1W
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CRYO-EM STRUCTURE AT 4.2 A RESOLUTION OF VACCINE-ELICITED ANTIBODY DFPH-A.15 IN COMPLEX WITH HIV-1 ENV BG505 DS-SOSIP, AND ANTIBODIES VRC03 AND PGT122
分子名称:Envelope glycoprotein gp120, DFPH-a.15 heavy chain, DFPH-a.15 Light chain, ...
著者Acharya, P., Kwong, P.D.
登録日2018-11-12
公開日2019-07-24
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.
Cell, 178, 2019
6NF2
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CRYO-EM STRUCTURE OF VACCINE-ELICITED ANTIBODY 0PV-C.01 IN COMPLEX WITH HIV-1 ENV BG505 DS-SOSIP AND ANTIBODIES VRC03 AND PGT122
分子名称:Envelope glycoprotein gp120, Envelope glycoprotein gp41, VRC03 Heavy Chain, ...
著者Gorman, J., Kwong, P.D.
登録日2018-12-18
公開日2019-07-24
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.
Cell, 178, 2019
6OSY
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CRYO-EM STRUCTURE OF VACCINE-ELICITED ANTIBODY 0PV-A.01 IN COMPLEX WITH HIV-1 ENV BG505 DS-SOSIP AND ANTIBODIES VRC03 AND PGT122
分子名称:BG505 gp120, PGT122 Heavy, PGT122 Light, ...
著者Gorman, J., Kwong, P.D.
登録日2019-05-02
公開日2019-07-24
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.
Cell, 178, 2019
6OT1
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CRYO-EM STRUCTURE OF VACCINE-ELICITED ANTIBODY 0PV-B.01 IN COMPLEX WITH HIV-1 ENV BG505 DS-SOSIP AND ANTIBODIES VRC03 AND PGT122
分子名称:Envelope glycoprotein gp41, BG505 gp120, 0PV-b.01 heavy, ...
著者Gorman, J., Kwong, P.D.
登録日2019-05-02
公開日2019-08-07
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.
Cell, 178, 2019
5WDF
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CRYSTAL STRUCTURE OF 10E8V4-5R+100CF FAB IN COMPLEX WITH HIV-1 GP41 PEPTIDE
分子名称:10E8v4-5R+100cF Fab heavy chain, FA10E8v4-5R+100cF FAB light chain, HIV-1 gp41 peptide
著者Kwon, Y.D., Kwong, P.D.
登録日2017-07-05
公開日2018-03-21
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Surface-Matrix Screening Identifies Semi-specific Interactions that Improve Potency of a Near Pan-reactive HIV-1-Neutralizing Antibody.
Cell Rep, 22, 2018
6MTJ
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CRYSTAL STRUCTURE OF HIV-1 BG505 SOSIP.664 PREFUSION ENV TRIMER BOUND TO SMALL MOLECULE HIV-1 ENTRY INHIBITOR BMS-378806 IN COMPLEX WITH HUMAN ANTIBODIES 3H109L AND 35O22 AT 2.9 ANGSTROM
分子名称:Envelope glycoprotein gp160, 35O22 scFv heavy chain portion, 35O22 scFv light chain portion, ...
著者Lai, Y.-T., Kwong, P.D.
登録日2018-10-19
公開日2019-01-16
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.336 Å)
主引用文献Lattice engineering enables definition of molecular features allowing for potent small-molecule inhibition of HIV-1 entry.
Nat Commun, 10, 2019
6MTN
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CRYSTAL STRUCTURE OF HIV-1 BG505 SOSIP.664 PREFUSION ENV TRIMER BOUND TO SMALL MOLECULE HIV-1 ENTRY INHIBITOR COMPOUND 484 IN COMPLEX WITH HUMAN ANTIBODIES 3H109L AND 35O22 AT 3.0 ANGSTROM
分子名称:Envelope glycoprotein gp160, 35O22 scFv heavy chain portion, 35O22 scFv light chain portion, ...
著者Lai, Y.-T., Kwong, P.D.
登録日2018-10-20
公開日2019-01-16
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Lattice engineering enables definition of molecular features allowing for potent small-molecule inhibition of HIV-1 entry.
Nat Commun, 10, 2019
6MU6
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CRYSTAL STRUCTURE OF HIV-1 BG505 SOSIP.664 PREFUSION ENV TRIMER BOUND TO SMALL MOLECULE HIV-1 ENTRY INHIBITOR BMS-814508 IN COMPLEX WITH HUMAN ANTIBODIES 3H109L AND 35O22 AT 3.2 ANGSTROM
分子名称:Envelope glycoprotein gp160, 35O22 scFv heavy chain portion, 35O22 scFv light chain portion, ...
著者Lai, Y.-T., Kwong, P.D.
登録日2018-10-22
公開日2019-01-16
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.551 Å)
主引用文献Lattice engineering enables definition of molecular features allowing for potent small-molecule inhibition of HIV-1 entry.
Nat Commun, 10, 2019
6MU7
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CRYSTAL STRUCTURE OF HIV-1 BG505 SOSIP.664 PREFUSION ENV TRIMER BOUND TO SMALL MOLECULE HIV-1 ENTRY INHIBITOR BMS-818251 IN COMPLEX WITH HUMAN ANTIBODIES 3H109L AND 35O22 AT 3.1 ANGSTROM
分子名称:Envelope glycoprotein gp160, 35O22 scFv heavy chain portion, 35O22 scFv light chain portion, ...
著者Lai, Y.-T., Kwong, P.D.
登録日2018-10-22
公開日2019-01-16
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.501 Å)
主引用文献Lattice engineering enables definition of molecular features allowing for potent small-molecule inhibition of HIV-1 entry.
Nat Commun, 10, 2019
6MU8
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CRYSTAL STRUCTURE OF HIV-1 BG505 SOSIP.664 PREFUSION ENV TRIMER BOUND TO SMALL MOLECULE HIV-1 ENTRY INHIBITOR BMS-386150 IN COMPLEX WITH HUMAN ANTIBODIES 3H109L AND 35O22 AT 3.5 ANGSTROM
分子名称:Envelope glycoprotein gp160, 35O22 scFv heavy chain portion, 35O22 scFv light chain portion, ...
著者Lai, Y.-T., Kwong, P.D.
登録日2018-10-22
公開日2019-01-16
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.993 Å)
主引用文献Lattice engineering enables definition of molecular features allowing for potent small-molecule inhibition of HIV-1 entry.
Nat Commun, 10, 2019
6MUF
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CRYSTAL STRUCTURE OF HIV-1 B41 SOSIP.664 PREFUSION ENV TRIMER IN COMPLEX WITH HUMAN ANTIBODIES 3H109L AND 35O22 AT 3.4 ANGSTROM
分子名称:Envelope glycoprotein gp160, 35O22 scFv heavy chain portion, 35O22 scFv light chain portion, ...
著者Lai, Y.-T., Kwong, P.D.
登録日2018-10-23
公開日2019-01-16
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.91 Å)
主引用文献Lattice engineering enables definition of molecular features allowing for potent small-molecule inhibition of HIV-1 entry.
Nat Commun, 10, 2019
6MUG
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CRYSTAL STRUCTURE OF HIV-1 B41 SOSIP.664 PREFUSION ENV TRIMER BOUND TO SMALL MOLECULE HIV-1 ENTRY INHIBITOR BMS-386150 IN COMPLEX WITH HUMAN ANTIBODIES 3H109L AND 35O22 AT 3.8 ANGSTROM
分子名称:Envelope glycoprotein gp160, 35O22 scFv heavy chain portion, 35O22 scFv light chain portion, ...
著者Lai, Y.-T., Kwong, P.D.
登録日2018-10-23
公開日2019-01-16
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.954 Å)
主引用文献Lattice engineering enables definition of molecular features allowing for potent small-molecule inhibition of HIV-1 entry.
Nat Commun, 10, 2019
6UBI
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N123-VRC34.05 HIV NEUTRALIZING ANTIBODY IN COMPLEX WITH HIV FUSION PEPTIDE RESIDUE 512-519
分子名称:VRC34.05 heavy chain, VRC34.05 light chain, HIV fusion peptide 512-519
著者Xu, K., Liu, K., Kwong, P.D.
登録日2019-09-11
公開日2020-03-18
最終更新日2020-04-22
実験手法X-RAY DIFFRACTION (1.903 Å)
主引用文献VRC34-Antibody Lineage Development Reveals How a Required Rare Mutation Shapes the Maturation of a Broad HIV-Neutralizing Lineage.
Cell Host Microbe, 27, 2020
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件を2020-08-05に公開中