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6ERI
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STRUCTURE OF THE CHLOROPLAST RIBOSOME WITH CHL-RRF AND HIBERNATION-PROMOTING FACTOR
Descriptor:23S ribosomal RNA, 4.5S ribosomal RNA, 50S ribosomal protein L2, ...
Authors:Perez Borema, A., Aibara, S., Paul, B., Tobiasson, V., Kimanius, D., Forsberg, B.O., Wallden, K., Lindahl, E., Amunts, A.
Deposit date:2017-10-18
Release date:2018-04-18
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structure of the chloroplast ribosome with chl-RRF and hibernation-promoting factor.
Nat Plants, 4, 2018
6PV7
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HUMAN ALPHA3BETA4 NICOTINIC ACETYLCHOLINE RECEPTOR IN COMPLEX WITH NICOTINE
Descriptor:Fusion protein of Neuronal acetylcholine receptor subunit alpha-3 and Soluble cytochrome b562, Fusion protein of Neuronal acetylcholine receptor subunit beta-4 and Soluble cytochrome b562, IgG2b Fab heavy chain, ...
Authors:Gharpure, A., Teng, J., Zhuang, Y., Noviello, C.M., Walsh, R.M., Cabuco, R., Howard, R.J., Zaveri, N.T., Lindahl, E., Hibbs, R.E.
Deposit date:2019-07-19
Release date:2019-09-11
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.34 Å)
Cite:Agonist Selectivity and Ion Permeation in the alpha 3 beta 4 Ganglionic Nicotinic Receptor.
Neuron, 104, 2019
6PV8
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HUMAN ALPHA3BETA4 NICOTINIC ACETYLCHOLINE RECEPTOR IN COMPLEX WITH AT-1001
Descriptor:Fusion protein of Neuronal acetylcholine receptor subunit alpha-3 and Soluble cytochrome b562, Fusion protein of Neuronal acetylcholine receptor subunit beta-4 and Soluble cytochrome b562, IgG2b Fab heavy chain, ...
Authors:Gharpure, A., Teng, J., Zhuang, Y., Noviello, C.M., Walsh, R.M., Cabuco, R., Howard, R.J., Zaveri, N.T., Lindahl, E., Hibbs, R.E.
Deposit date:2019-07-19
Release date:2019-09-11
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.87 Å)
Cite:Agonist Selectivity and Ion Permeation in the alpha 3 beta 4 Ganglionic Nicotinic Receptor.
Neuron, 104, 2019
5LG3
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X-RAY STRUCTURE OF A PENTAMERIC LIGAND GATED ION CHANNEL FROM ERWINIA CHRYSANTHEMI (ELIC) IN COMPLEX WITH CHLORPROMAZINE
Descriptor:Gamma-aminobutyric-acid receptor subunit beta-1, 3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine
Authors:Nys, M., Wijckmans, E., Farinha, A., Brams, M., Spurny, R., Ulens, C.
Deposit date:2016-07-05
Release date:2016-10-26
Last modified:2016-11-09
Method:X-RAY DIFFRACTION (3.567 Å)
Cite:Allosteric binding site in a Cys-loop receptor ligand-binding domain unveiled in the crystal structure of ELIC in complex with chlorpromazine.
Proc.Natl.Acad.Sci.USA, 113, 2016
5LID
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X-RAY STRUCTURE OF A PENTAMERIC LIGAND GATED ION CHANNEL FROM ERWINIA CHRYSANTHEMI (ELIC) IN COMPLEX WITH BROMOPROMAZINE
Descriptor:Cys-loop ligand-gated ion channel, bromopromazine
Authors:Nys, M., Wijckmans, E., Farinha, A., Brams, M., Spurny, R., Ulens, C.
Deposit date:2016-07-14
Release date:2016-10-26
Last modified:2019-10-16
Method:X-RAY DIFFRACTION (4.5 Å)
Cite:Allosteric binding site in a Cys-loop receptor ligand-binding domain unveiled in the crystal structure of ELIC in complex with chlorpromazine.
Proc.Natl.Acad.Sci.USA, 113, 2016
6HMF
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D-FAMILY DNA POLYMERASE - DP1 SUBUNIT (3'-5' PROOF-READING EXONUCLEASE) H451 PROOF-READING DEFICIENT VARIANT
Descriptor:DNA polymerase II small subunit, FE (III) ION, ZINC ION, ...
Authors:Raia, P., Delarue, M., Sauguet, L.
Deposit date:2018-09-12
Release date:2019-01-30
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of the DP1-DP2 PolD complex bound with DNA and its implications for the evolutionary history of DNA and RNA polymerases.
PLoS Biol., 17, 2019
6HMS
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CRYO-EM MAP OF DNA POLYMERASE D FROM PYROCOCCUS ABYSSI IN COMPLEX WITH DNA
Descriptor:DNA polymerase II small subunit, DNA polymerase II large subunit,DNA polymerase II large subunit, DNA (5'-D(*GP*AP*GP*AP*CP*GP*GP*GP*CP*CP*GP*CP*GP*TP*C)-3'), ...
Authors:Raia, P., Carroni, M., Sauguet, L.
Deposit date:2018-09-12
Release date:2019-01-30
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (7.1 Å)
Cite:Structure of the DP1-DP2 PolD complex bound with DNA and its implications for the evolutionary history of DNA and RNA polymerases.
PLoS Biol., 17, 2019
6T8H
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CRYO-EM STRUCTURE OF THE DNA-BOUND POLD-PCNA PROCESSIVE COMPLEX FROM P. ABYSSI
Descriptor:DNA polymerase sliding clamp, DNA polymerase II small subunit, DP2 subunit of D-family DNA-polymerase, ...
Authors:Madru, C., Raia, P., Hugonneau Beaufet, I., Pehau-Arnaudet, G., England, P., Lindhal, E., Delarue, M., Carroni, M., Sauguet, L.
Deposit date:2019-10-24
Release date:2020-03-04
Last modified:2020-04-08
Method:ELECTRON MICROSCOPY (3.77 Å)
Cite:Structural basis for the increased processivity of D-family DNA polymerases in complex with PCNA.
Nat Commun, 11, 2020
4HQJ
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CRYSTAL STRUCTURE OF NA+,K+-ATPASE IN THE NA+-BOUND STATE
Descriptor:Sodium/potassium-transporting ATPase subunit alpha-1, Sodium/potassium-transporting ATPase subunit beta-1, Na+/K+ ATPase gamma subunit transcript variant a, ...
Authors:Nyblom, M., Reinhard, L., Gourdon, P., Nissen, P.
Deposit date:2012-10-25
Release date:2013-10-02
Last modified:2014-09-10
Method:X-RAY DIFFRACTION (4.3 Å)
Cite:Crystal structure of Na+, K(+)-ATPase in the Na(+)-bound state.
Science, 342, 2013
5MUO
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X-RAY STRUCTURE OF THE 2-22' LOCALLY-CLOSED MUTANT OF GLIC IN COMPLEX WITH PROPOFOL
Descriptor:Proton-gated ion channel, DODECYL-BETA-D-MALTOSIDE, CHLORIDE ION, ...
Authors:Fourati, Z., Ruza, R.R., Delarue, M.
Deposit date:2017-01-13
Release date:2018-02-14
Last modified:2018-06-20
Method:X-RAY DIFFRACTION (3.19 Å)
Cite:Structural Basis for a Bimodal Allosteric Mechanism of General Anesthetic Modulation in Pentameric Ligand-Gated Ion Channels.
Cell Rep, 23, 2018
5MUR
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X-RAY STRUCTURE OF THE F14'A MUTANT OF GLIC IN COMPLEX WITH PROPOFOL
Descriptor:Proton-gated ion channel, ACETATE ION, CHLORIDE ION, ...
Authors:Sauguet, L., Fourati, Z., Delarue, M.
Deposit date:2017-01-13
Release date:2018-02-14
Last modified:2019-10-16
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural Basis for a Bimodal Allosteric Mechanism of General Anesthetic Modulation in Pentameric Ligand-Gated Ion Channels.
Cell Rep, 23, 2018
5MVN
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X-RAY STRUCTURE OF THE M205W MUTANT OF GLIC IN COMPLEX WITH PROPOFOL
Descriptor:Proton-gated ion channel, ACETATE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ...
Authors:Fourati, Z., Delarue, M.
Deposit date:2017-01-16
Release date:2018-02-14
Last modified:2019-10-16
Method:X-RAY DIFFRACTION (3.49 Å)
Cite:Structural Basis for a Bimodal Allosteric Mechanism of General Anesthetic Modulation in Pentameric Ligand-Gated Ion Channels.
Cell Rep, 23, 2018
5MZQ
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X-RAY STRUCTURE OF THE M205W MUTANT OF GLIC IN COMPLEX WITH BROMOFORM
Descriptor:Proton-gated ion channel, ACETATE ION, 1,2-DIOCTANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ...
Authors:Fourati, Z., Delarue, M.
Deposit date:2017-02-01
Release date:2018-02-28
Last modified:2019-10-16
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Basis for a Bimodal Allosteric Mechanism of General Anesthetic Modulation in Pentameric Ligand-Gated Ion Channels.
Cell Rep, 23, 2018
5NKJ
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X-RAY STRUCTURE OF THE N239C MUTANT OF GLIC
Descriptor:Proton-gated ion channel
Authors:Hu, H., Fourati, Z., Delarue, M.
Deposit date:2017-03-31
Release date:2018-06-20
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (3.74 Å)
Cite:Structural Basis for a Bimodal Allosteric Mechanism of General Anesthetic Modulation in Pentameric Ligand-Gated Ion Channels.
Cell Rep, 23, 2018
6EMX
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X-RAY STRUCTURE OF THE N15'C MUTANT OF GLIC IN COMPLEX WITH BROMOFORM
Descriptor:Proton-gated ion channel, CHLORIDE ION, SODIUM ION, ...
Authors:Fourati, Z., Delarue, M.
Deposit date:2017-10-03
Release date:2018-06-20
Last modified:2019-10-16
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural Basis for a Bimodal Allosteric Mechanism of General Anesthetic Modulation in Pentameric Ligand-Gated Ion Channels.
Cell Rep, 23, 2018
6QV6
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CRYOEM STRUCTURE OF THE HUMAN CLC-1 CHLORIDE CHANNEL, MEMBRANE DOMAIN
Descriptor:Chloride channel protein 1
Authors:Wang, K.T., Gourdon, P.E., Zhou, Z.H.
Deposit date:2019-03-01
Release date:2019-05-08
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.63 Å)
Cite:Structure of the human ClC-1 chloride channel.
Plos Biol., 17, 2019
6QVB
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CRYOEM STRUCTURE OF THE HUMAN CLC-1 CHLORIDE CHANNEL, CBS STATE 3
Descriptor:Chloride channel protein 1
Authors:Wang, K.T., Gourdon, P.E., Zhou, Z.H.
Deposit date:2019-03-01
Release date:2019-05-08
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (4.34 Å)
Cite:Structure of the human ClC-1 chloride channel.
Plos Biol., 17, 2019
6QVC
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CRYOEM STRUCTURE OF THE HUMAN CLC-1 CHLORIDE CHANNEL, CBS STATE 1
Descriptor:Chloride channel protein 1
Authors:Wang, K.T., Gourdon, P.E., Zhou, Z.H.
Deposit date:2019-03-01
Release date:2019-05-08
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structure of the human ClC-1 chloride channel.
Plos Biol., 17, 2019
6QVD
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CRYOEM STRUCTURE OF THE HUMAN CLC-1 CHLORIDE CHANNEL, CBS STATE 2
Descriptor:Chloride channel protein 1
Authors:Wang, K.T., Gourdon, P.E., Zhou, Z.H.
Deposit date:2019-03-01
Release date:2019-05-08
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (4.34 Å)
Cite:Structure of the human ClC-1 chloride channel.
Plos Biol., 17, 2019
6QVU
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CRYOEM STRUCTURE OF THE HUMAN CLC-1 CHLORIDE CHANNEL, LOW PH
Descriptor:Chloride channel protein 1
Authors:Wang, K.T., Gourdon, P.E., Zhou, Z.H.
Deposit date:2019-03-05
Release date:2019-05-08
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structure of the human ClC-1 chloride channel.
Plos Biol., 17, 2019
6T7X
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CRYSTAL STRUCTURE OF PCNA FROM P. ABYSSI
Descriptor:DNA polymerase sliding clamp
Authors:Madru, C., Raia, P., Hugonneau Beaufet, I., Delarue, M., Carroni, M., Sauguet, L.
Deposit date:2019-10-23
Release date:2020-03-04
Last modified:2020-04-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for the increased processivity of D-family DNA polymerases in complex with PCNA.
Nat Commun, 11, 2020
6T7Y
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STRUCTURE OF PCNA BOUND TO CPIP MOTIF OF DP2 FROM P. ABYSSI
Descriptor:DNA polymerase sliding clamp, cPIP motif from the DP2 large subunit of PolD
Authors:Madru, C., Raia, P., Hugonneau Beaufet, I., Delarue, M., Carroni, M., Sauguet, L.
Deposit date:2019-10-23
Release date:2020-03-04
Last modified:2020-04-08
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis for the increased processivity of D-family DNA polymerases in complex with PCNA.
Nat Commun, 11, 2020
6V4A
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AN OPEN CONFORMATION OF A PENTAMEIC LIGAND-GATED ION CHANNEL WITH ADDITIONAL N-TERMINAL DOMAIN
Descriptor:Neur_chan_LBD domain-containing protein, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, PHOSPHATIDYLGLYCEROL-PHOSPHOGLYCEROL
Authors:Delarue, M., Hu, H.D.
Deposit date:2019-11-27
Release date:2020-06-03
Method:X-RAY DIFFRACTION (3.83 Å)
Cite:Structural basis for allosteric transitions of a multi-domain pentameric ligand-gated ion channel
Proc.Natl.Acad.Sci.USA, 2020
6V4B
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DECLIC N-TERMINAL DOMAIN 34-202
Descriptor:Neur_chan_LBD domain-containing protein, GLYCEROL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
Authors:Delarue, M., Hu, H.D.
Deposit date:2019-11-27
Release date:2020-06-03
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural basis for allosteric transitions of a multi-domain pentameric ligand-gated ion channel
Proc.Natl.Acad.Sci.USA, 2020
6V4S
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A CLOSED PORE CONFORMATION OF A PENTAMEIC LIGAND-GATED ION CHANNEL WITH ADDITIONAL N-TERMINAL DOMAIN
Descriptor:Neur_chan_LBD domain-containing protein, CALCIUM ION, SODIUM ION, ...
Authors:Delarue, M., Hu, H.D.
Deposit date:2019-11-29
Release date:2020-06-03
Method:X-RAY DIFFRACTION (3.55 Å)
Cite:Structural basis for allosteric transitions of a multi-domain pentameric ligand-gated ion channel
Proc.Natl.Acad.Sci.USA, 2020