Author results

4Y1U
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COMPLEX OF HUMAN GALECTIN-1 AND GALBETA1-4GLCNAC
分子名称:Galectin-1, BETA-D-GALACTOSE, BETA-METHYL-N-ACETYL-D-GLUCOSAMINE
著者Lin, H.Y., Hsieh, T.J., Lin, C.H.
登録日2015-02-09
公開日2016-04-06
実験手法X-RAY DIFFRACTION (1.762 Å)
主引用文献Structural basis of human galectin-1 inhibition with Ki values in the micro- to nanomolar range
To Be Published
4Y1V
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COMPLEX OF HUMAN GALECTIN-1 AND GALBETA1-3GLCNAC
分子名称:Galectin-1, BETA-METHYL-N-ACETYL-D-GLUCOSAMINE, BETA-D-GALACTOSE
著者Lin, H.Y., Hsieh, T.J., Lin, C.H.
登録日2015-02-09
公開日2016-04-06
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献Structural basis of human galectin-1 inhibition with Ki values in the micro- to nanomolar range
To Be Published
4Y1X
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COMPLEX OF HUMAN GALECTIN-1 AND GALBETA1-4(6OSO3)GLCNAC
分子名称:Galectin-1, BETA-D-GALACTOSE, methyl 2-(acetylamino)-2-deoxy-6-O-sulfo-beta-D-glucopyranoside
著者Lin, H.Y., Hsieh, T.J., Lin, C.H.
登録日2015-02-09
公開日2016-04-06
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Structural basis of human galectin-1 inhibition with Ki values in the micro- to nanomolar range
To Be Published
4Y1Y
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COMPLEX OF HUMAN GALECTIN-1 AND (6OSO3)GALBETA1-3GLCNAC
分子名称:Galectin-1, BETA-D-GALACTOSE, methyl 2-(acetylamino)-2-deoxy-6-O-sulfo-beta-D-glucopyranoside
著者Lin, H.Y., Hsieh, T.J., Lin, C.H.
登録日2015-02-09
公開日2016-04-06
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Structural basis of human galectin-1 inhibition with Ki values in the micro- to nanomolar range
To Be Published
4Y1Z
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COMPLEX OF HUMAN GALECTIN-1 AND GALBETA1-4(6CO2)GLCNAC
分子名称:Galectin-1, BETA-D-GALACTOSE, methyl 2-(acetylamino)-2-deoxy-beta-D-glucopyranosiduronic acid
著者Lin, H.Y., Hsieh, T.J., Lin, C.H.
登録日2015-02-09
公開日2016-04-06
実験手法X-RAY DIFFRACTION (2.23 Å)
主引用文献Structural basis of human galectin-1 inhibition with Ki values in the micro- to nanomolar range
To Be Published
4Y20
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COMPLEX OF HUMAN GALECTIN-1 AND NEUACALPHA2-3GALBETA1-4GLC
分子名称:Galectin-1, 5-(ACETYLAMINO)-3,5-DIDEOXYNON-2-ULOPYRANONOSYL-(2->3)-BETA-D-LYXO-HEXOPYRANOSYL-(1->4)HEXOPYRANOSE
著者Lin, H.Y., Hsieh, T.J., Lin, C.H.
登録日2015-02-09
公開日2016-04-06
実験手法X-RAY DIFFRACTION (2.204 Å)
主引用文献Structural basis of human galectin-1 inhibition with Ki values in the micro- to nanomolar range
To Be Published
4Y22
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COMPLEX OF HUMAN GALECTIN-1 AND (3OSO3)GALBETA1-3GLCNAC
分子名称:Galectin-1, O3-SULFONYLGALACTOSE, BETA-METHYL-N-ACETYL-D-GLUCOSAMINE
著者Lin, H.Y., Hsieh, T.J., Lin, C.H.
登録日2015-02-09
公開日2016-04-06
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis of human galectin-1 inhibition with Ki values in the micro- to nanomolar range
To Be Published
4Y26
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COMPLEX OF HUMAN GALECTIN-7 AND GALBETA1-3(6OSO3)GLCNAC
分子名称:Galectin-7, BETA-D-GALACTOSE, methyl 2-(acetylamino)-2-deoxy-6-O-sulfo-beta-D-glucopyranoside
著者Lin, H.Y., Hsieh, T.J., Lin, C.H.
登録日2015-02-09
公開日2016-04-06
実験手法X-RAY DIFFRACTION (2.611 Å)
主引用文献Structural basis of human galectin-1 inhibition with Ki values in the micro- to nanomolar range
To Be Published
5YWG
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CRYSTAL STRUCTURE OF ARABIDOPSIS THALIANA HPPD COMPLEXED WITH MESOTRIONE
分子名称:4-hydroxyphenylpyruvate dioxygenase, COBALT (II) ION, 2-[(4-methylsulfonyl-2-nitro-phenyl)-oxidanyl-methylidene]cyclohexane-1,3-dione
著者Lin, H.Y., Yang, W.C.
登録日2017-11-29
公開日2019-01-16
最終更新日2019-03-20
実験手法X-RAY DIFFRACTION (2.603 Å)
主引用文献Molecular insights into the mechanism of 4-hydroxyphenylpyruvate dioxygenase inhibition: enzyme kinetics, X-ray crystallography and computational simulations.
FEBS J., 286, 2019
4Y24
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COMPLEX OF HUMAN GALECTIN-1 AND TD-139
分子名称:Galectin-1, 3-deoxy-3-[4-(3-fluorophenyl)-1H-1,2,3-triazol-1-yl]-beta-D-galactopyranosyl 3-deoxy-3-[4-(3-fluorophenyl)-1H-1,2,3-triazol-1-yl]-1-thio-beta-D-galactopyranoside
著者Lin, H.Y., Hsieh, T.J., Lin, C.H.
登録日2015-02-09
公開日2016-04-27
最終更新日2016-08-03
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献Dual thio-digalactoside-binding modes of human galectins as the structural basis for the design of potent and selective inhibitors.
Sci Rep, 6, 2016
5H9P
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CRYSTAL STRUCTURE OF HUMAN GALECTIN-3 CRD IN COMPLEX WITH TD139
分子名称:Galectin-3, 3-deoxy-3-[4-(3-fluorophenyl)-1H-1,2,3-triazol-1-yl]-beta-D-galactopyranosyl 3-deoxy-3-[4-(3-fluorophenyl)-1H-1,2,3-triazol-1-yl]-1-thio-beta-D-galactopyranoside
著者Hsieh, T.J., Lin, H.Y., Lin, C.H.
登録日2015-12-29
公開日2016-06-29
最終更新日2016-07-27
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Dual thio-digalactoside-binding modes of human galectins as the structural basis for the design of potent and selective inhibitors
Sci Rep, 6, 2016
5H9Q
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CRYSTAL STRUCTURE OF HUMAN GALECTIN-7 IN COMPLEX WITH TD139
分子名称:Galectin-7, 3-deoxy-3-[4-(3-fluorophenyl)-1H-1,2,3-triazol-1-yl]-beta-D-galactopyranosyl 3-deoxy-3-[4-(3-fluorophenyl)-1H-1,2,3-triazol-1-yl]-1-thio-beta-D-galactopyranoside
著者Hsieh, T.J., Lin, H.Y., Lin, C.H.
登録日2015-12-29
公開日2016-06-29
最終更新日2016-07-27
実験手法X-RAY DIFFRACTION (1.931 Å)
主引用文献Dual thio-digalactoside-binding modes of human galectins as the structural basis for the design of potent and selective inhibitors
Sci Rep, 6, 2016
5H9R
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CRYSTAL STRUCTURE OF HUMAN GALECTIN-3 CRD IN COMPLEX WITH TAZTDG
分子名称:Galectin-3, (2~{S},3~{R},4~{S},5~{R},6~{R})-2-[(2~{S},3~{R},4~{S},5~{R},6~{R})-4-[4-(3-fluorophenyl)-1,2,3-triazol-1-yl]-6-(hydroxymethyl)-3,5-bis(oxidanyl)oxan-2-yl]sulfanyl-6-(hydroxymethyl)oxane-3,4,5-triol
著者Hsieh, T.J., Lin, H.Y., Lin, C.H.
登録日2015-12-29
公開日2016-06-29
最終更新日2016-07-27
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Dual thio-digalactoside-binding modes of human galectins as the structural basis for the design of potent and selective inhibitors
Sci Rep, 6, 2016
5H9S
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CRYSTAL STRUCTURE OF HUMAN GALECTIN-7 IN COMPLEX WITH TAZTDG
分子名称:Galectin-7, (2~{S},3~{R},4~{S},5~{R},6~{R})-2-[(2~{S},3~{R},4~{S},5~{R},6~{R})-4-[4-(3-fluorophenyl)-1,2,3-triazol-1-yl]-6-(hydroxymethyl)-3,5-bis(oxidanyl)oxan-2-yl]sulfanyl-6-(hydroxymethyl)oxane-3,4,5-triol
著者Hsieh, T.J., Lin, H.Y., Lin, C.H.
登録日2015-12-29
公開日2016-06-29
最終更新日2016-07-27
実験手法X-RAY DIFFRACTION (1.821 Å)
主引用文献Dual thio-digalactoside-binding modes of human galectins as the structural basis for the design of potent and selective inhibitors
Sci Rep, 6, 2016
5Z18
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THE CRYSTAL STRUCTURE OF RUMINOCOCCUS GNAVUS BETA-GLUCURONIDASE
分子名称:Beta-glucuronidase
著者Dashnyam, P., Lin, H.Y., Lin, C.H.
登録日2017-12-25
公開日2018-12-12
実験手法X-RAY DIFFRACTION (2.495 Å)
主引用文献Dissection of the substrate preference and structure of gut microbial beta-glucuronidases identifies the major bacteria causing xenobiotic toxicity
To Be Published
5Z19
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THE CRYSTAL STRUCTURE OF RUMINOCOCCUS GNAVUS BETA-GLUCURONIDASE IN COMPLEX WITH URONIC ISOFAGOMINE
分子名称:Beta-glucuronidase, (3S,4R,5R)-4,5-dihydroxypiperidine-3-carboxylic acid
著者Dashnyam, P., Lin, H.Y., Lin, C.H.
登録日2017-12-25
公開日2018-12-12
最終更新日2019-04-03
実験手法X-RAY DIFFRACTION (2.503 Å)
主引用文献Dissection of the substrate preference and structure of gut microbial beta-glucuronidases identifies the major bacteria causing xenobiotic toxicity
To Be Published
5Z1A
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THE CRYSTAL STRUCTURE OF BACTEROIDES FRAGILIS BETA-GLUCURONIDASE IN COMPLEX WITH URONIC ISOFAGOMINE
分子名称:Putative beta-galactosidase, (3S,4R,5R)-4,5-dihydroxypiperidine-3-carboxylic acid
著者Dashnyam, P., Lin, H.Y., Lin, C.H.
登録日2017-12-25
公開日2018-12-12
実験手法X-RAY DIFFRACTION (1.859 Å)
主引用文献Dissection of the substrate preference and structure of gut microbial-glucuronidases identifies the major bacteria causing xenobiotic toxicity
To Be Published
5Z1B
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STRUCTURE OF BIFIDOBACTERIUM DENTIUM BETA-GLUCURONIDASE COMPLEXED WITH COUMARIN-3-O-GLUCURONIDE
分子名称:Glycosyl hydrolase family 2, TIM barrel domain protein, BETA-D-GLUCOPYRANURONIC ACID, ...
著者Dashnyam, P., Lin, H.Y., Lin, C.H.
登録日2017-12-25
公開日2018-12-12
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Dissection of the substrate preference and structure of gut microbial-glucuronidases identifies the major bacteria causing xenobiotic toxicity
To Be Published
4XBL
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CRYSTAL STRUCTURE OF HUMAN GALECTIN-1 IN COMPLEX WITH TYPE 1 N-ACETYLLACTOSAMINE
分子名称:Galectin-1, BETA-D-GALACTOSE, N-ACETYL-D-GLUCOSAMINE
著者Hsieh, T.J., Lin, H.Y., Lin, C.H.
登録日2014-12-17
公開日2015-05-20
実験手法X-RAY DIFFRACTION (1.931 Å)
主引用文献Structural Basis Underlying the Binding Preference of Human Galectins-1, -3 and -7 for Gal beta 1-3/4GlcNAc.
Plos One, 10, 2015
4XBN
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CRYSTAL STRUCTURE OF HUMAN GALECTIN-3 CRD IN COMPLEX WITH TYPE 1 N-ACETYLLACTOSAMINE
分子名称:Galectin-3, BETA-D-GALACTOSE, N-ACETYL-D-GLUCOSAMINE
著者Hsieh, T.J., Lin, H.Y., Lin, C.H.
登録日2014-12-17
公開日2015-05-20
実験手法X-RAY DIFFRACTION (2.208 Å)
主引用文献Structural Basis Underlying the Binding Preference of Human Galectins-1, -3 and -7 for Gal beta 1-3/4GlcNAc.
Plos One, 10, 2015
4XBQ
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CRYSTAL STRUCTURE OF HUMAN GALECTIN-7 IN COMPLEX WITH TYPE 1 N-ACETYLLACTOSAMINE
分子名称:Galectin-7, BETA-D-GALACTOSE, N-ACETYL-D-GLUCOSAMINE
著者Hsieh, T.J., Lin, H.Y., Lin, C.H.
登録日2014-12-17
公開日2015-05-20
実験手法X-RAY DIFFRACTION (2.234 Å)
主引用文献Structural Basis Underlying the Binding Preference of Human Galectins-1, -3 and -7 for Gal beta 1-3/4GlcNAc.
Plos One, 10, 2015
5XGK
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CRYSTAL STRUCTURE OF ARABIDOPSIS THALIANA 4-HYDROXYPHENYLPYRUVATE DIOXYGENASE (ATHPPD) COMPLEXED WITH ITS SUBSTRATE 4-HYDROXYPHENYLPYRUVATE ACID (HPPA)
分子名称:4-hydroxyphenylpyruvate dioxygenase, (2S)-2-hydroxy-3-(4-hydroxyphenyl)propanoic acid, FE (III) ION, ...
著者Yang, G.F., Yang, W.C., Lin, H.Y.
登録日2017-04-14
公開日2018-09-19
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of Arabidopsis thaliana 4-hydroxyphenylpyruvate dioxygenase (AtHPPD) complexed with its substrate 4-hydroxyphenylpyruvate acid (HPPA)
To Be Published
5YWH
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CRYSTAL STRUCTURE OF ARABIDOPSIS THALIANA HPPD COMPLEXED WITH Y13508
分子名称:4-hydroxyphenylpyruvate dioxygenase, FE (III) ION, [1,3-diethyl-2,2-bis(oxidanylidene)-2$l^{6},1,3-benzothiadiazol-5-yl]-(1-methyl-5-oxidanyl-pyrazol-4-yl)methanone
著者Yang, W.C., Lin, H.Y.
登録日2017-11-29
公開日2019-01-16
実験手法X-RAY DIFFRACTION (2.72 Å)
主引用文献Crystal structure of Arabidopsis thaliana HPPD complexed with Y13508
To be published
5YWK
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CRYSTAL STRUCTURE OF ARABIDOPSIS THALIANA HPPD COMPLEXED WITH BENQUITRIONE-METHYL
分子名称:4-hydroxyphenylpyruvate dioxygenase, COBALT (II) ION, 1,5-dimethyl-3-(2-methylphenyl)-6-(2-oxidanyl-6-oxidanylidene-cyclohexen-1-yl)carbonyl-quinazoline-2,4-dione
著者Yang, W.C., Lin, H.Y.
登録日2017-11-29
公開日2019-01-16
実験手法X-RAY DIFFRACTION (2.804 Å)
主引用文献Crystal structure of Arabidopsis thaliana HPPD complexed with Benquitrione-Methyl
To be published
6ISD
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CRYSTAL STRUCTURE OF ARABIDOPSIS THALIANA HPPD COMPLEXED WITH SULCOTRIONE
分子名称:4-hydroxyphenylpyruvate dioxygenase, 2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione, COBALT (II) ION
著者Yang, W.C., Yang, G.F.
登録日2018-11-16
公開日2018-11-28
最終更新日2019-03-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Molecular insights into the mechanism of 4-hydroxyphenylpyruvate dioxygenase inhibition: enzyme kinetics, X-ray crystallography and computational simulations.
FEBS J., 286, 2019
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