Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
5HLO
DownloadVisualize
BU of 5hlo by Molmil
Crystal structure of calcium and zinc-bound human S100A8 in space group C2221
Descriptor: ACETATE ION, CACODYLATE ION, CALCIUM ION, ...
Authors:Lin, H, Andersen, G.R, Yatime, L.
Deposit date:2016-01-15
Release date:2016-06-08
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of human S100A8 in complex with zinc and calcium.
Bmc Struct.Biol., 16, 2016
5HLV
DownloadVisualize
BU of 5hlv by Molmil
Crystal structure of calcium and zinc-bound human S100A8 in space group P212121
Descriptor: ACETATE ION, CALCIUM ION, CHLORIDE ION, ...
Authors:Lin, H, Andersen, G.R, Yatime, L.
Deposit date:2016-01-15
Release date:2016-06-08
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of human S100A8 in complex with zinc and calcium.
Bmc Struct.Biol., 16, 2016
6IS8
DownloadVisualize
BU of 6is8 by Molmil
Crystal structure of ZmMoc1 D115N mutant in complex with Holliday junction
Descriptor: DNA (33-MER), MAGNESIUM ION, Monokaryotic chloroplast 1, ...
Authors:Lin, Z, Lin, H, Zhang, D, Yuan, C.
Deposit date:2018-11-15
Release date:2019-10-23
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Structural basis of sequence-specific Holliday junction cleavage by MOC1.
Nat.Chem.Biol., 15, 2019
6IS9
DownloadVisualize
BU of 6is9 by Molmil
Crystal Structure of ZmMOC1
Descriptor: Monokaryotic chloroplast 1
Authors:Lin, Z, Lin, H, Zhang, D, Yuan, C.
Deposit date:2018-11-15
Release date:2019-10-23
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Structural basis of sequence-specific Holliday junction cleavage by MOC1.
Nat.Chem.Biol., 15, 2019
6JRG
DownloadVisualize
BU of 6jrg by Molmil
Crystal structure of ZmMoc1 H253A mutant in complex with Holliday junction
Descriptor: DNA (32-MER), DNA (33-MER), MAGNESIUM ION, ...
Authors:Lin, Z, Lin, H, Zhang, D, Yuan, C.
Deposit date:2019-04-03
Release date:2019-10-23
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.005 Å)
Cite:Structural basis of sequence-specific Holliday junction cleavage by MOC1.
Nat.Chem.Biol., 15, 2019
6JRF
DownloadVisualize
BU of 6jrf by Molmil
Crystal structure of ZmMoc1-Holliday junction Complex in the presence of Calcium
Descriptor: CALCIUM ION, DNA (33-MER), Monokaryotic chloroplast 1, ...
Authors:Lin, Z, Lin, H, Zhang, D, Yuan, C.
Deposit date:2019-04-03
Release date:2019-10-23
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.047 Å)
Cite:Structural basis of sequence-specific Holliday junction cleavage by MOC1.
Nat.Chem.Biol., 15, 2019
7XKE
DownloadVisualize
BU of 7xke by Molmil
Cryo-EM structure of DHEA-ADGRG2-FL-Gs complex
Descriptor: 3-BETA-HYDROXY-5-ANDROSTEN-17-ONE, Adhesion G-protein coupled receptor G2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Guo, S.C, Xiao, P, Lin, H, Sun, J.P, Yu, X.
Deposit date:2022-04-19
Release date:2022-08-10
Last modified:2023-03-15
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structures of the ADGRG2-G s complex in apo and ligand-bound forms.
Nat.Chem.Biol., 18, 2022
7XKF
DownloadVisualize
BU of 7xkf by Molmil
Cryo-EM structure of DHEA-ADGRG2-BT-Gs complex at lower state
Descriptor: 3-BETA-HYDROXY-5-ANDROSTEN-17-ONE, Adhesion G-protein coupled receptor G2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Guo, S.C, Xiao, P, Lin, H, Sun, J.P, Yu, X.
Deposit date:2022-04-19
Release date:2022-08-10
Last modified:2023-03-15
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:Structures of the ADGRG2-G s complex in apo and ligand-bound forms.
Nat.Chem.Biol., 18, 2022
7XKD
DownloadVisualize
BU of 7xkd by Molmil
Cryo-EM structure of DHEA-ADGRG2-BT-Gs complex
Descriptor: 3-BETA-HYDROXY-5-ANDROSTEN-17-ONE, Adhesion G-protein coupled receptor G2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Guo, S.C, Xiao, P, Lin, H, Sun, J.P, Yu, X.
Deposit date:2022-04-19
Release date:2022-08-10
Last modified:2023-03-15
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:Structures of the ADGRG2-G s complex in apo and ligand-bound forms.
Nat.Chem.Biol., 18, 2022
6K1S
DownloadVisualize
BU of 6k1s by Molmil
Discovery of Potent and Selective Covalent Protein Arginine Methyltransferase (PRMT5) Inhibitors
Descriptor: 1,2-ETHANEDIOL, 2-[[7-[(2~{R},3~{R},4~{S},5~{R})-5-[(~{R})-(4-chlorophenyl)-oxidanyl-methyl]-3,4-bis(oxidanyl)oxolan-2-yl]pyrrolo[2,3-d]pyrimidin-4-yl]amino]ethanal, DIMETHYL SULFOXIDE, ...
Authors:Tong, S, Lin, H.
Deposit date:2019-05-12
Release date:2019-06-19
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Discovery of Potent and Selective Covalent Protein Arginine Methyltransferase 5 (PRMT5) Inhibitors.
Acs Med.Chem.Lett., 10, 2019
3ZJ6
DownloadVisualize
BU of 3zj6 by Molmil
Crystal of Raucaffricine Glucosidase in complex with inhibitor
Descriptor: (1R,2S,3S,4R,5R)-4-(cyclohexylmethylamino)-5-(hydroxymethyl)cyclopentane-1,2,3-triol, RAUCAFFRICINE-O-BETA-D-GLUCOSIDASE, SULFATE ION
Authors:Xia, L, Lin, H, Panjikar, S, Ruppert, M, Castiglia, A, Rajendran, C, Wang, M, Schuebel, H, Warzecha, H, Jaeger, V, Stoeckigt, J.
Deposit date:2013-01-17
Release date:2014-01-29
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Ligand Structures of Synthetic Deoxa-Pyranosylamines with Raucaffricine and Strictosidine Glucosidases Provide Structural Insights Into Their Binding and Inhibitory Behaviours.
J.Enzyme.Inhib.Med.Chem., 30, 2015
8TMR
DownloadVisualize
BU of 8tmr by Molmil
Crystal structure of KPC-44 carbapenemase complexed with avibactam
Descriptor: (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, 1,2-ETHANEDIOL, PHOSPHATE ION, ...
Authors:Sun, Z, Palzkill, T, Hu, L, Lin, H, Sankaran, B, Wang, J, Prasad, B.
Deposit date:2023-07-30
Release date:2023-12-06
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.37 Å)
Cite:Klebsiella pneumoniae carbapenemase variant 44 acquires ceftazidime-avibactam resistance by altering the conformation of active-site loops.
J.Biol.Chem., 300, 2023
8TMT
DownloadVisualize
BU of 8tmt by Molmil
Crystal structure of KPC-44 carbapenemase in complex with vaborbactam
Descriptor: 1,2-ETHANEDIOL, GLYCEROL, LITHIUM ION, ...
Authors:Sun, Z, Palzkill, T, Hu, L, Neetu, N, Lin, H, Sankaran, B, Wang, J, Prasad, B.
Deposit date:2023-07-30
Release date:2023-12-06
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Klebsiella pneumoniae carbapenemase variant 44 acquires ceftazidime-avibactam resistance by altering the conformation of active-site loops.
J.Biol.Chem., 300, 2023
8TJM
DownloadVisualize
BU of 8tjm by Molmil
Crystal structure of KPC-44 carbapenemase
Descriptor: 1,2-ETHANEDIOL, SULFATE ION, beta-lactamase
Authors:Sun, Z, Palzkill, T, Hu, L, Lin, H, Sankaran, B, Wang, J, Prasad, B.
Deposit date:2023-07-23
Release date:2023-12-06
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.28 Å)
Cite:Klebsiella pneumoniae carbapenemase variant 44 acquires ceftazidime-avibactam resistance by altering the conformation of active-site loops.
J.Biol.Chem., 300, 2023
8TN0
DownloadVisualize
BU of 8tn0 by Molmil
Crystal structure of KPC-44 carbapenemase w/o cryoprotectant
Descriptor: SULFATE ION, beta-lactamase
Authors:Sun, Z, Palzkill, T, Hu, L, Lin, H, Sankaran, B, Wang, J, Prasad, B.
Deposit date:2023-07-31
Release date:2023-12-06
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.31 Å)
Cite:Klebsiella pneumoniae carbapenemase variant 44 acquires ceftazidime-avibactam resistance by altering the conformation of active-site loops.
J.Biol.Chem., 300, 2023
3ZJ8
DownloadVisualize
BU of 3zj8 by Molmil
Crystal structure of strictosidine glucosidase in complex with inhibitor-2
Descriptor: (1R,2S,3S,4R,5R)-4-[(4-bromophenyl)methylamino]-5-(hydroxymethyl)cyclopentane-1,2,3-triol, STRICTOSIDINE-O-BETA-D-GLUCOSIDASE
Authors:Xia, L, Lin, H, Panjikar, S, Ruppert, M, Castiglia, A, Rajendran, C, Wang, M, Schuebel, H, Warzecha, H, Jaeger, V, Stoeckigt, J.
Deposit date:2013-01-17
Release date:2014-02-05
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:Ligand Structures of Synthetic Deoxa-Pyranosylamines with Raucaffricine and Strictosidine Glucosidases Provide Structural Insights Into Their Binding and Inhibitory Behaviours.
J.Enzyme.Inhib.Med.Chem., 30, 2015
3ZJ7
DownloadVisualize
BU of 3zj7 by Molmil
Crystal structure of strictosidine glucosidase in complex with inhibitor-1
Descriptor: (1R,2S,3S,4R,5R)-4-(cyclohexylamino)-5-(hydroxymethyl)cyclopentane-1,2,3-triol, STRICTOSIDINE-O-BETA-D-GLUCOSIDASE
Authors:Xia, L, Lin, H, Panjikar, S, Ruppert, M, Castiglia, A, Rajendran, C, Wang, M, Schuebel, H, Warzecha, H, Jaeger, V, Stoeckigt, J.
Deposit date:2013-01-17
Release date:2014-02-05
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Ligand Structures of Synthetic Deoxa-Pyranosylamines with Raucaffricine and Strictosidine Glucosidases Provide Structural Insights Into Their Binding and Inhibitory Behaviours.
J.Enzyme.Inhib.Med.Chem., 30, 2015
6PAV
DownloadVisualize
BU of 6pav by Molmil
Structure of Human NMT1 with products CoA and myristoyl-lysine peptide with acetylated N-terminus
Descriptor: ARF6 peptide, COENZYME A, GLYCEROL, ...
Authors:Price, I.R, Lin, H.
Deposit date:2019-06-12
Release date:2020-03-11
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:NMT1 and NMT2 are lysine myristoyltransferases regulating the ARF6 GTPase cycle.
Nat Commun, 11, 2020
6PAU
DownloadVisualize
BU of 6pau by Molmil
Structure of Human NMT2 with myristoyl-lysine peptide and CoA products
Descriptor: 4'-diphospho pantetheine, Arf6 peptide, GLYCEROL, ...
Authors:Price, I.R, Lin, H.
Deposit date:2019-06-11
Release date:2020-03-11
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:NMT1 and NMT2 are lysine myristoyltransferases regulating the ARF6 GTPase cycle.
Nat Commun, 11, 2020
6Q2E
DownloadVisualize
BU of 6q2e by Molmil
Crystal structure of Methanobrevibacter smithii Dph2 bound to 5'-methylthioadenosine
Descriptor: 2-(3-amino-3-carboxypropyl)histidine synthase, 5'-DEOXY-5'-METHYLTHIOADENOSINE, CHLORIDE ION, ...
Authors:Fenwick, M.K, Dong, M, Lin, H, Ealick, S.E.
Deposit date:2019-08-07
Release date:2019-10-16
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.768 Å)
Cite:The Crystal Structure of Dph2 in Complex with Elongation Factor 2 Reveals the Structural Basis for the First Step of Diphthamide Biosynthesis.
Biochemistry, 58, 2019
6Q2P
DownloadVisualize
BU of 6q2p by Molmil
Crystal structure of mouse viperin bound to cytidine triphosphate and S-adenosylhomocysteine
Descriptor: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, CYTIDINE-5'-TRIPHOSPHATE, ...
Authors:Fenwick, M.K, Dong, M, Lin, H, Ealick, S.E.
Deposit date:2019-08-08
Release date:2020-01-22
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.452 Å)
Cite:Structural Basis of the Substrate Selectivity of Viperin.
Biochemistry, 59, 2020
6Q2Q
DownloadVisualize
BU of 6q2q by Molmil
Crystal structure of mouse viperin bound to uridine triphosphate and S-adenosylhomocysteine
Descriptor: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, IRON/SULFUR CLUSTER, ...
Authors:Fenwick, M.K, Dong, M, Lin, H, Ealick, S.E.
Deposit date:2019-08-08
Release date:2020-01-22
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.892 Å)
Cite:Structural Basis of the Substrate Selectivity of Viperin.
Biochemistry, 59, 2020
6Q2D
DownloadVisualize
BU of 6q2d by Molmil
Crystal structure of Methanobrevibacter smithii Dph2 in complex with Methanobrevibacter smithii elongation factor 2
Descriptor: 2-(3-amino-3-carboxypropyl)histidine synthase, Elongation factor 2, IRON/SULFUR CLUSTER
Authors:Fenwick, M.K, Dong, M, Lin, H, Ealick, S.E.
Deposit date:2019-08-07
Release date:2019-10-16
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.45 Å)
Cite:The Crystal Structure of Dph2 in Complex with Elongation Factor 2 Reveals the Structural Basis for the First Step of Diphthamide Biosynthesis.
Biochemistry, 58, 2019
4EXP
DownloadVisualize
BU of 4exp by Molmil
Structure of mouse Interleukin-34 in complex with mouse FMS
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-34, Macrophage colony-stimulating factor 1 receptor
Authors:Liu, H, Leo, C, Chen, X, Wong, B.R, Williams, L.T, Lin, H, He, X.
Deposit date:2012-04-30
Release date:2012-05-30
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The mechanism of shared but distinct CSF-1R signaling by the non-homologous cytokines IL-34 and CSF-1.
Biochim.Biophys.Acta, 1824, 2012
7KPF
DownloadVisualize
BU of 7kpf by Molmil
NME2 bound to myristoyl-CoA
Descriptor: GLYCEROL, MAGNESIUM ION, Nucleoside diphosphate kinase B, ...
Authors:Price, I.R, Lin, H.
Deposit date:2020-11-11
Release date:2022-02-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:A Chemical Proteomic Approach reveals the regulation of NME1/2 and cancer metastasis by Long-Chain Fatty Acyl Coenzyme A
To Be Published

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon