Author results

1GNE
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THE THREE-DIMENSIONAL STRUCTURE OF GLUTATHIONE S-TRANSFERASE OF SCHISTOSOMA JAPONICUM FUSED WITH A CONSERVED NEUTRALIZING EPITOPE ON GP41 OF HUMAN IMMUNODEFICIENCY VIRUS TYPE 1
Descriptor:GLUTATHIONE S-TRANSFERASE, GLUTATHIONE
Authors:Lim, K., Ho, J.X., Keeling, K., Gilliland, G.L., Ji, X., Ruker, F., Carter, D.C.
Deposit date:1994-06-16
Release date:1994-11-30
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Three-dimensional structure of Schistosoma japonicum glutathione S-transferase fused with a six-amino acid conserved neutralizing epitope of gp41 from HIV.
Protein Sci., 3, 1994
2R82
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PYRUVATE PHOSPHATE DIKINASE (PPDK) TRIPLE MUTANT R219E/E271R/S262D ADAPTS A SECOND CONFORMATIONAL STATE
Descriptor:Pyruvate, phosphate dikinase, SULFATE ION
Authors:Lim, K., Read, R.J., Chen, C.C., Herzberg, O.
Deposit date:2007-09-10
Release date:2008-01-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Swiveling domain mechanism in pyruvate phosphate dikinase.
Biochemistry, 46, 2007
3L2D
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GLYCOCYAMINE KINASE, BETA-BETA HOMODIMER FROM MARINE WORM NAMALYCASTIS SP.
Descriptor:Glycocyamine kinase beta chain
Authors:Lim, K., Pullalarevu, S., Herzberg, O.
Deposit date:2009-12-15
Release date:2010-03-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis for the mechanism and substrate specificity of glycocyamine kinase, a phosphagen kinase family member.
Biochemistry, 49, 2010
3L2E
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GLYCOCYAMINE KINASE, ALPHA-BETA HETERODIMER FROM MARINE WORM NAMALYCASTIS SP.
Descriptor:Glycocyamine kinase alpha chain, Glycocyamine kinase beta chain
Authors:Lim, K., Pullalarevu, S., Herzberg, O.
Deposit date:2009-12-15
Release date:2010-03-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis for the mechanism and substrate specificity of glycocyamine kinase, a phosphagen kinase family member.
Biochemistry, 49, 2010
4V7N
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GLYCOCYAMINE KINASE, BETA-BETA HOMODIMER FROM MARINE WORM NAMALYCASTIS SP., WITH TRANSITION STATE ANALOG MG(II)-ADP-NO3-GLYCOCYAMINE.
Descriptor:Glycocyamine kinase beta chain, GUANIDINO ACETATE, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Lim, K., Pullalarevu, S., Herzberg, O.
Deposit date:2009-12-15
Release date:2014-07-09
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for the mechanism and substrate specificity of glycocyamine kinase, a phosphagen kinase family member.
Biochemistry, 49, 2010
1AZF
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CHICKEN EGG WHITE LYSOZYME CRYSTAL GROWN IN BROMIDE SOLUTION
Descriptor:LYSOZYME, BROMIDE ION
Authors:Lim, K., Nadarajah, A., Forsythe, E.L., Pusey, M.L.
Deposit date:1997-11-17
Release date:1998-02-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Locations of bromide ions in tetragonal lysozyme crystals.
Acta Crystallogr.,Sect.D, 54, 1998
1IM8
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CRYSTAL STRUCTURE OF YECO FROM HAEMOPHILUS INFLUENZAE (HI0319), A METHYLTRANSFERASE WITH A BOUND S-ADENOSYLHOMOCYSTEINE
Descriptor:YecO, CHLORIDE ION, S-ADENOSYL-L-HOMOSELENOCYSTEINE
Authors:Lim, K., Zhang, H., Tempczyk, A., Bonander, N., Toedt, J., Howard, A., Eisenstein, E., Herzberg, O., Structure 2 Function Project (S2F)
Deposit date:2001-05-10
Release date:2001-11-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of YecO from Haemophilus influenzae (HI0319) reveals a methyltransferase fold and a bound S-adenosylhomocysteine.
Proteins, 45, 2001
1J7G
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STRUCTURE OF YIHZ FROM HAEMOPHILUS INFLUENZAE (HI0670), A D-TYR-TRNA(TYR) DEACYLASE
Descriptor:D-tyrosyl-tRNA(Tyr) deacylase
Authors:Lim, K., Herzberg, O., Structure 2 Function Project (S2F)
Deposit date:2001-05-16
Release date:2003-04-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:A Catalytic Mechanism for D-Tyr-tRNATyr Deacylase Based on the Crystal Structure of Hemophilus influenzae HI0670
J.Biol.Chem., 278, 2003
1J85
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STRUCTURE OF YIBK FROM HAEMOPHILUS INFLUENZAE (HI0766), A TRUNCATED SEQUENCE HOMOLOG OF TRNA (GUANOSINE-2'-O-) METHYLTRANSFERASE (SPOU)
Descriptor:YibK
Authors:Lim, K., Zhang, H., Toedt, J., Tempcyzk, A., Krajewski, W., Howard, A., Eisenstein, E., Herzberg, O., Structure 2 Function Project (S2F)
Deposit date:2001-05-20
Release date:2003-02-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the YibK methyltransferase from Haemophilus influenzae (HI0766): A cofactor bound at a site formed by a knot
Proteins, 51, 2003
1J8B
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STRUCTURE OF YBAB FROM HAEMOPHILUS INFLUENZAE (HI0442), A PROTEIN OF UNKNOWN FUNCTION
Descriptor:YbaB
Authors:Lim, K., Tempcyzk, A., Toedt, J., Parsons, J.F., Howard, A., Eisenstein, E., Herzberg, O., Structure 2 Function Project (S2F)
Deposit date:2001-05-21
Release date:2003-01-14
Last modified:2012-09-26
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structure of YbaB from Haemophilus influenzae (HI0442), a protein of unknown function coexpressed with the recombinational DNA repair protein RecR
Proteins, 50, 2003
1MW5
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STRUCTURE OF HI1480 FROM HAEMOPHILUS INFLUENZAE
Descriptor:HYPOTHETICAL PROTEIN HI1480
Authors:Lim, K., Sarikaya, E., Howard, A., Galkin, A., Herzberg, O., Structure 2 Function Project (S2F)
Deposit date:2002-09-27
Release date:2003-11-18
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Novel structure and nucleotide binding properties of HI1480 from Haemophilus influenzae: a protein with no known sequence homologues
PROTEINS: STRUCT.,FUNCT.,GENET., 56, 2004
1MXI
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STRUCTURE OF YIBK FROM HAEMOPHILUS INFLUENZAE (HI0766): A METHYLTRANSFERASE WITH A COFACTOR BOUND AT A SITE FORMED BY A KNOT
Descriptor:Hypothetical tRNA/rRNA methyltransferase HI0766, IODIDE ION, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Lim, K., Zhang, H., Tempczyk, A., Bonander, N., Toedt, J., Howard, A., Eisenstein, E., Herzberg, O., Structure 2 Function Project (S2F)
Deposit date:2002-10-02
Release date:2003-02-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of the YibK methyltransferase from Haemophilus influenzae (HI0766): a Cofactor Bound at a Site Formed by a Knot
Proteins, 51, 2003
1X6I
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CRYSTAL STRUCTURE OF YGFY FROM ESCHERICHIA COLI
Descriptor:Hypothetical protein ygfY
Authors:Lim, K., Doseeva, V., Sarikaya Demirkan, E., Pullalarevu, S., Krajewski, W., Galkin, A., Howard, A., Herzberg, O., Structure 2 Function Project (S2F)
Deposit date:2004-08-11
Release date:2005-02-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Crystal structure of the YgfY from Escherichia coli, a protein that may be involved in transcriptional regulation
Proteins, 58, 2005
1X6J
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CRYSTAL STRUCTURE OF YGFY FROM ESCHERICHIA COLI
Descriptor:Hypothetical protein ygfY
Authors:Lim, K., Doseeva, V., Sarikaya Demirkan, E., Pullalarevu, S., Krajewski, W., Galkin, A., Howard, A., Herzberg, O., Structure 2 Function Project (S2F)
Deposit date:2004-08-11
Release date:2005-02-08
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of the YgfY from Escherichia coli, a protein that may be involved in transcriptional regulation
Proteins, 58, 2005
2PCP
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ANTIBODY FAB COMPLEXED WITH PHENCYCLIDINE
Descriptor:IMMUNOGLOBULIN, 1-(PHENYL-1-CYCLOHEXYL)PIPERIDINE
Authors:Lim, K., Owens, S.M., Arnold, L., Sacchettini, J.C., Linthicum, D.S.
Deposit date:1998-06-02
Release date:1999-01-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of monoclonal 6B5 Fab complexed with phencyclidine.
J.Biol.Chem., 273, 1998
4JZ7
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CARBAMATE KINASE FROM GIARDIA LAMBLIA BOUND TO AMP-PNP
Descriptor:Carbamate kinase, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Lim, K., Herzberg, O.
Deposit date:2013-04-02
Release date:2013-06-05
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structures of Carbamate Kinase from Giardia lamblia Bound with Citric Acid and AMP-PNP.
Plos One, 8, 2013
4JZ8
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CARBAMATE KINASE FROM GIARDIA LAMBLIA BOUND TO CITRIC ACID
Descriptor:Carbamate kinase, CITRIC ACID
Authors:Lim, K., Herzberg, O.
Deposit date:2013-04-02
Release date:2013-06-05
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structures of Carbamate Kinase from Giardia lamblia Bound with Citric Acid and AMP-PNP.
Plos One, 8, 2013
4JZ9
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CARBAMATE KINASE FROM GIARDIA LAMBLIA BOUND TO CITRIC ACID
Descriptor:Carbamate kinase, CITRIC ACID
Authors:Lim, K., Herzberg, O.
Deposit date:2013-04-02
Release date:2013-06-05
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structures of Carbamate Kinase from Giardia lamblia Bound with Citric Acid and AMP-PNP.
Plos One, 8, 2013
4OLC
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CARBAMATE KINASE FROM GIARDIA LAMBLIA THIOCARBAMOYLATED BY DISULFIRAM ON CYS242
Descriptor:Carbamate kinase, CITRIC ACID, DIETHYLCARBAMODITHIOIC ACID
Authors:Lim, K., Herzberg, O.
Deposit date:2014-01-23
Release date:2014-02-26
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Basis for Inactivation of Giardia lamblia Carbamate Kinase by Disulfiram.
J.Biol.Chem., 289, 2014
3CA8
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CRYSTAL STRUCTURE OF ESCHERICHIA COLI YDCF, AN S-ADENOSYL-L-METHIONINE UTILIZING ENZYME
Descriptor:Protein ydcF, SULFATE ION, (4S)-2-METHYL-2,4-PENTANEDIOL
Authors:Lim, K., Chao, K., Lehmann, C., Herzberg, O., Structure 2 Function Project (S2F)
Deposit date:2008-02-19
Release date:2008-05-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The Escherichia coli YdcF binds S-adenosyl-L-methionine and adopts an alpha/beta-fold characteristic of nucleotide-utilizing enzymes.
Proteins, 72, 2008
1J8D
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STRUCTURE OF THE METAL-FREE FORM OF THE DEOXY-D-MANNOSE-OCTULOSONATE 8-PHOSPHATE PHOSPHATASE (YRBI) FROM HAEMOPHILUS INFLUENZAE (HI1679)
Descriptor:deoxy-D-mannose-octulosonate 8-phosphate phosphatase, GLYCEROL
Authors:Lim, K., Herzberg, O., Structure 2 Function Project (S2F)
Deposit date:2001-05-21
Release date:2002-02-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:From structure to function: YrbI from Haemophilus influenzae (HI1679) is a phosphatase.
Proteins, 46, 2002
1K1E
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STRUCTURE OF THE COBALT-BOUND FORM OF THE DEOXY-D-MANNOSE-OCTULOSONATE 8-PHOSPHATE PHOSPHATASE (YRBI) FROM HAEMOPHILUS INFLUENZAE (HI1679)
Descriptor:deoxy-D-mannose-octulosonate 8-phosphate phosphatase, COBALT (II) ION, MERCURY (II) ION, ...
Authors:Lim, K., Herzberg, O., Structure 2 Function Project (S2F)
Deposit date:2001-09-25
Release date:2002-02-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:From structure to function: YrbI from Haemophilus influenzae (HI1679) is a phosphatase.
Proteins, 46, 2002
2HWG
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STRUCTURE OF PHOSPHORYLATED ENZYME I OF THE PHOSPHOENOLPYRUVATE:SUGAR PHOSPHOTRANSFERASE SYSTEM
Descriptor:Phosphoenolpyruvate-protein phosphotransferase, MAGNESIUM ION, OXALATE ION
Authors:Lim, K., Teplyakov, A., Herzberg, O.
Deposit date:2006-08-01
Release date:2006-11-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of phosphorylated enzyme I, the phosphoenolpyruvate:sugar phosphotransferase system sugar translocation signal protein.
Proc.Natl.Acad.Sci.Usa, 103, 2006
4GAH
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HUMAN ACYL-COA THIOESTERASES 4 IN COMPLEX WITH UNDECAN-2-ONE-COA INHIBITOR
Descriptor:Thioesterase superfamily member 4, [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(3R)-2,2-dimethyl-3-oxidanyl-4-oxidanylidene-4-[[3-oxidanylidene-3-[2-[(2R)-2-oxidanylundecyl]sulfanylethylamino]propyl]amino]butyl] hydrogen phosphate
Authors:Lim, K., Pathak, M.C., Herzberg, O.
Deposit date:2012-07-25
Release date:2012-08-29
Last modified:2012-10-31
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Correlation of structure and function in the human hotdog-fold enzyme hTHEM4.
Biochemistry, 51, 2012
2GC8
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STRUCTURE OF A PROLINE SULFONAMIDE INHIBITOR BOUND TO HCV NS5B POLYMERASE
Descriptor:RNA-directed RNA polymerase, 1-[(2-AMINO-4-CHLORO-5-METHYLPHENYL)SULFONYL]-L-PROLINE
Authors:Gopalsamy, A., Chopra, R., Lim, K., Ciszewski, G., Shi, M., Curran, K.J., Sukits, S.F., Svenson, K., Bard, J., Ellingboe, J.W., Agarwal, A., Krishnamurthy, G., Howe, A.Y., Orlowski, M., Feld, B., O'connell, J., Mansour, T.S.
Deposit date:2006-03-13
Release date:2006-06-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Discovery of Proline Sulfonamides as Potent and Selective Hepatitis C Virus NS5b Polymerase Inhibitors. Evidence for a New NS5b Polymerase Binding Site.
J.Med.Chem., 49, 2006
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