Author results

5GZN
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STRUCTURE OF NEUTRALIZING ANTIBODY BOUND TO ZIKA ENVELOPE PROTEIN
分子名称:Genome polyprotein, Antibody Heavy chain, Antibody light chain
著者Wang, Q., Yang, H., Liu, X., Dai, L., Ma, T., Qi, J., Wong, G., Peng, R., Liu, S., Li, J., Li, S., Song, J., Liu, J., He, J., Yuan, H., Xiong, Y., Liao, Y., Li, J., Yang, J., Tong, Z., Griffin, B., Bi, Y., Liang, M., Xu, X., Cheng, G., Wang, P., Qiu, X., Kobinger, G., Shi, Y., Yan, J., Gao, G.F.
登録日2016-09-29
公開日2016-12-28
最終更新日2017-09-27
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Molecular determinants of human neutralizing antibodies isolated from a patient infected with Zika virus
Sci Transl Med, 8, 2016
5GZO
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STRUCTURE OF NEUTRALIZING ANTIBODY BOUND TO ZIKA ENVELOPE PROTEIN
分子名称:Genome polyprotein, Antibody heavy chain, Antibody light chain
著者Wang, Q., Yang, H., Liu, X., Dai, L., Ma, T., Qi, J., Wong, G., Peng, R., Liu, S., Li, J., Li, S., Song, J., Liu, J., He, J., Yuan, H., Xiong, Y., Liao, Y., Li, J., Yang, J., Tong, Z., Griffin, B., Bi, Y., Liang, M., Xu, X., Cheng, G., Wang, P., Qiu, X., Kobinger, G., Shi, Y., Yan, J., Gao, G.F.
登録日2016-09-29
公開日2017-01-18
最終更新日2017-08-30
実験手法X-RAY DIFFRACTION (2.755 Å)
主引用文献Molecular determinants of human neutralizing antibodies isolated from a patient infected with Zika virus
Sci Transl Med, 8, 2016
4XX5
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STRUCTURE OF PI3K GAMMA IN COMPLEX WITH AN INHIBITOR
分子名称:Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, N-[5-(5-methoxypyridin-3-yl)-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridin-2-yl]acetamide
著者Collier, P.N., Messersmith, D., Le Tiran, A., Bandarage, U.K., Boucher, C., Come, J., Cottrell, K.M., Damagnez, V., Doran, J.D., Griffith, J.P., Khare-Pandit, S., Krueger, E.B., Ledeboer, M.W., Ledford, B., Liao, Y., Mahajan, S., Moody, C.S., Wang, T., Xu, J., Aronov, A.M.
登録日2015-01-29
公開日2015-08-05
実験手法X-RAY DIFFRACTION (2.76 Å)
主引用文献Structure of PI3K gamma in complex with an inhibitor
To Be Published
4XZ4
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STRUCTURE OF PI3K GAMMA IN COMPLEX WITH AN INHIBITOR
分子名称:Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, N-[5-(6-methoxypyrazin-2-yl)-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridin-2-yl]acetamide
著者Collier, P.N., Messersmith, D., Le Tiran, A., Bandarage, U.K., Boucher, C., Come, J., Cottrell, K.M., Damagnez, V., Doran, J.D., Griffith, J.P., Khare-Pandit, S., Krueger, E.B., Ledeboer, M.W., Ledford, B., Liao, Y., Mahajan, S., Moody, C.S., Wang, T., Xu, J., Aronov, A.M.
登録日2015-02-03
公開日2016-02-03
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of PI3K gamma in complex with an inhibitor
To Be Published
4P8O
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S. AUREUS GYRASE BOUND TO AN AMINOBENZIMIDAZOLE UREA INHIBITOR
分子名称:DNA gyrase subunit B, 1-ethyl-3-[5-(5-fluoropyridin-3-yl)-7-(pyrimidin-2-yl)-1H-benzimidazol-2-yl]urea
著者Jacobs, M.D.
登録日2014-03-31
公開日2014-10-29
最終更新日2015-09-30
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Second-generation antibacterial benzimidazole ureas: discovery of a preclinical candidate with reduced metabolic liability.
J.Med.Chem., 57, 2014
5GZR
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ZIKA VIRUS E PROTEIN COMPLEXED WITH A NEUTRALIZING ANTIBODY Z23-FAB
分子名称:structural protein E, strutural protein M, Z23 Fab heavy chain, ...
著者Gao, G.G., Shi, Y., Peng, R., Liu, S.
登録日2016-10-01
公開日2016-11-30
最終更新日2016-12-28
実験手法ELECTRON MICROSCOPY (9.4 Å)
主引用文献Molecular determinants of human neutralizing antibodies isolated from a patient infected with Zika virus
Sci Transl Med, 8, 2016
2MFJ
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SOLUTION STRUCTURE OF BLO T 19, A MINOR DUST MITE ALLERGEN FROM BLOMIA TROPICALIS
分子名称:Blo t 19
著者Naik, M.T., Naik, N., Huang, T.
登録日2013-10-15
公開日2014-11-19
実験手法SOLUTION NMR
主引用文献Solution structure of Blo 1 19
To be Published
4N78
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THE WAVE REGULATORY COMPLEX LINKS DIVERSE RECEPTORS TO THE ACTIN CYTOSKELETON
分子名称:Cytoplasmic FMR1-interacting protein 1, Nck-associated protein 1, Wiskott-Aldrich syndrome protein family member 1, ...
著者Chen, Z.C.
登録日2013-10-15
公開日2014-02-05
実験手法X-RAY DIFFRACTION (2.43 Å)
主引用文献The WAVE Regulatory Complex Links Diverse Receptors to the Actin Cytoskeleton.
Cell(Cambridge,Mass.), 156, 2014
5H2S
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SOLUTION STRUCTURE OF TILAPIA PISCIDIN 4 (TP4) FROM OREOCHROMIS NILOTICUS
分子名称:Piscidin-4
著者Wei, S., Chen, C.
登録日2016-10-17
公開日2017-10-25
実験手法SOLUTION NMR
主引用文献Solution structure of Tilapia piscidin 4, an antimicrobial peptide effective against multidrug resistant Helicobacter pylori
To Be Published
6C1S
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PHOSPHOINOSITIDE 3-KINASE GAMMA BOUND TO AN PYRROLOPYRIDINONE INHIBITOR
分子名称:Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, {4-[2-(5,6-dimethoxypyridin-3-yl)-5-oxo-5,7-dihydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-1H-pyrazol-1-yl}acetonitrile, SULFATE ION
著者Jacobs, M.D., Griffin, J.P.
登録日2018-01-05
公開日2018-06-27
最終更新日2018-07-11
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Design and Synthesis of a Novel Series of Orally Bioavailable, CNS-Penetrant, Isoform Selective Phosphoinositide 3-Kinase gamma (PI3K gamma ) Inhibitors with Potential for the Treatment of Multiple Sclerosis (MS).
J. Med. Chem., 61, 2018