Author results

3J5P
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STRUCTURE OF TRPV1 ION CHANNEL DETERMINED BY SINGLE PARTICLE ELECTRON CRYO-MICROSCOPY
Descriptor:Transient receptor potential cation channel subfamily V member 1
Authors:Liao, M., Cao, E., Julius, D., Cheng, Y.
Deposit date:2013-10-28
Release date:2013-12-04
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.275 Å)
Cite:Structure of the TRPV1 ion channel determined by electron cryo-microscopy.
Nature, 504, 2013
3J5Q
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STRUCTURE OF TRPV1 ION CHANNEL IN COMPLEX WITH DKTX AND RTX DETERMINED BY SINGLE PARTICLE ELECTRON CRYO-MICROSCOPY
Descriptor:Transient receptor potential cation channel subfamily V member 1, Double-knot toxin
Authors:Liao, M., Cao, E., Julius, D., Cheng, Y.
Deposit date:2013-10-28
Release date:2013-12-04
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:TRPV1 structures in distinct conformations reveal activation mechanisms.
Nature, 504, 2013
3J5R
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RECONSTRUCTION OF TRPV1 ION CHANNEL IN COMPLEX WITH CAPSAICIN BY SINGLE PARTICLE CRYO-MICROSCOPY
Descriptor:Transient receptor potential cation channel subfamily V member 1
Authors:Liao, M., Cao, E., Julius, D., Cheng, Y.
Deposit date:2013-10-28
Release date:2013-12-04
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:TRPV1 structures in distinct conformations reveal activation mechanisms.
Nature, 504, 2013
5U07
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CRISPR RNA-GUIDED SURVEILLANCE COMPLEX
Descriptor:CRISPR-associated protein, Cse3 family, Cse2, ...
Authors:Xiao, Y., Luo, M., Hayes, R.P., Kim, J., Ng, S., Ding, F., Liao, M., Ke, A.
Deposit date:2016-11-23
Release date:2017-08-09
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structure Basis for Directional R-loop Formation and Substrate Handover Mechanisms in Type I CRISPR-Cas System.
Cell, 170, 2017
5U0A
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CRISPR RNA-GUIDED SURVEILLANCE COMPLEX
Descriptor:CRISPR-associated protein, Cse3 family, Cse1 family, ...
Authors:Xiao, Y., Luo, M., Hayes, R.P., Kim, J., Ng, S., Ding, F., Liao, M., Ke, A.
Deposit date:2016-11-23
Release date:2017-08-09
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structure Basis for Directional R-loop Formation and Substrate Handover Mechanisms in Type I CRISPR-Cas System.
Cell, 170, 2017
6C66
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CRISPR RNA-GUIDED SURVEILLANCE COMPLEX, PRE-NICKING
Descriptor:CRISPR-associated helicase, Cas3 family, CRISPR-associated protein, ...
Authors:Xiao, Y., Luo, M., Liao, M., Ke, A.
Deposit date:2018-01-17
Release date:2018-06-27
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.66 Å)
Cite:Structure basis for RNA-guided DNA degradation by Cascade and Cas3.
Science, 361, 2018
3JBW
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CRYO-ELECTRON MICROSCOPY STRUCTURE OF RAG PAIRED COMPLEX (WITH NBD, NO SYMMETRY)
Descriptor:V(D)J recombination-activating protein 1, V(D)J recombination-activating protein 2, 12-RSS signal end forward strand, ...
Authors:Ru, H., Chambers, M.G., Fu, T.-M., Tong, A.B., Liao, M., Wu, H.
Deposit date:2015-10-21
Release date:2015-12-09
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (4.631 Å)
Cite:Molecular Mechanism of V(D)J Recombination from Synaptic RAG1-RAG2 Complex Structures.
Cell(Cambridge,Mass.), 163, 2015
3JBX
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CRYO-ELECTRON MICROSCOPY STRUCTURE OF RAG SIGNAL END COMPLEX (C2 SYMMETRY)
Descriptor:V(D)J recombination-activating protein 1, V(D)J recombination-activating protein 2, 5'-D(*CP*AP*CP*AP*GP*TP*GP*CP*TP*AP*CP*AP*GP*AP*C)-3', ...
Authors:Ru, H., Chambers, M.G., Fu, T.-M., Tong, A.B., Liao, M., Wu, H.
Deposit date:2015-10-22
Release date:2015-12-09
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Molecular Mechanism of V(D)J Recombination from Synaptic RAG1-RAG2 Complex Structures.
Cell(Cambridge,Mass.), 163, 2015
3JBY
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CRYO-ELECTRON MICROSCOPY STRUCTURE OF RAG PAIRED COMPLEX (C2 SYMMETRY)
Descriptor:V(D)J recombination-activating protein 1, V(D)J recombination-activating protein 2, 5'-D(P*CP*AP*CP*AP*GP*TP*GP*CP*TP*AP*CP*AP*GP*AP*C)-3', ...
Authors:Ru, H., Chambers, M.G., Fu, T.-M., Tong, A.B., Liao, M., Wu, H.
Deposit date:2015-10-22
Release date:2015-12-09
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Molecular Mechanism of V(D)J Recombination from Synaptic RAG1-RAG2 Complex Structures.
Cell(Cambridge,Mass.), 163, 2015
5TTP
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CRYO-EM STRUCTURE OF MSBA-NANODISC WITH ADP-VANADATE
Descriptor:Lipid A export ATP-binding/permease protein MsbA
Authors:Mi, W., Walz, T., Liao, M.
Deposit date:2016-11-04
Release date:2017-09-20
Last modified:2017-09-27
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Structural basis of MsbA-mediated lipopolysaccharide transport.
Nature, 549, 2017
5TV4
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3D CRYO-EM RECONSTRUCTION OF NUCLEOTIDE-FREE MSBA IN LIPID NANODISC
Descriptor:Lipid A export ATP-binding/permease protein MsbA, 2-amino-2-deoxy-alpha-D-glucopyranose, 3-DEOXY-D-MANNO-OCT-2-ULOSONIC ACID, ...
Authors:Mi, W., Walz, T., Liao, M.
Deposit date:2016-11-08
Release date:2017-09-20
Last modified:2017-11-08
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structural basis of MsbA-mediated lipopolysaccharide transport.
Nature, 549, 2017
5V6P
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CRYOEM STRUCTURE OF THE ERAD-ASSOCIATED E3 UBIQUITIN-PROTEIN LIGASE HRD1
Descriptor:ERAD-associated E3 ubiquitin-protein ligase HRD1
Authors:Schoebel, S., Mi, W., Stein, A., Rapoport, T.A., Liao, M.
Deposit date:2017-03-17
Release date:2017-08-16
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Cryo-EM structure of the protein-conducting ERAD channel Hrd1 in complex with Hrd3.
Nature, 548, 2017
5V7V
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CRYO-EM STRUCTURE OF ERAD-ASSOCIATED E3 UBIQUITIN-PROTEIN LIGASE COMPONENT HRD3
Descriptor:ERAD-associated E3 ubiquitin-protein ligase component HRD3, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE
Authors:Mi, W., Schoebel, S., Stein, A., Rapoport, T.A., Liao, M.
Deposit date:2017-03-20
Release date:2017-08-16
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Cryo-EM structure of the protein-conducting ERAD channel Hrd1 in complex with Hrd3.
Nature, 548, 2017
6CP3
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MONOMER YEAST ATP SYNTHASE (F1FO) RECONSTITUTED IN NANODISC WITH INHIBITOR OF OLIGOMYCIN BOUND.
Descriptor:ATP synthase subunit 9, mitochondrial, ATP synthase subunit 5, ...
Authors:Srivastava, A.P., Luo, M., Symersky, J., Liao, M.F., Mueller, D.M.
Deposit date:2018-03-13
Release date:2018-04-11
Last modified:2018-05-23
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:High-resolution cryo-EM analysis of the yeast ATP synthase in a lipid membrane.
Science, 360, 2018
6CP5
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MONOMER YEAST ATP SYNTHASE FO RECONSTITUTED IN NANODISC WITH INHIBITOR OF OLIGOMYCIN BOUND GENERATED FROM FOCUSED REFINEMENT.
Descriptor:ATP synthase subunit 9, mitochondrial, ATP synthase protein 8, ...
Authors:Srivastava, A.P., Luo, M., Symersky, J., Liao, M.F., Mueller, D.M.
Deposit date:2018-03-13
Release date:2018-04-11
Last modified:2018-05-23
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:High-resolution cryo-EM analysis of the yeast ATP synthase in a lipid membrane.
Science, 360, 2018
6CP6
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MONOMER YEAST ATP SYNTHASE (F1FO) RECONSTITUTED IN NANODISC.
Descriptor:ATP synthase subunit 9, mitochondrial, ATP synthase subunit 5, ...
Authors:Srivastava, A.P., Luo, M., Symersky, J., Liao, M.F., Mueller, D.M.
Deposit date:2018-03-13
Release date:2018-04-11
Last modified:2018-05-23
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:High-resolution cryo-EM analysis of the yeast ATP synthase in a lipid membrane.
Science, 360, 2018
6CP7
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MONOMER YEAST ATP SYNTHASE FO RECONSTITUTED IN NANODISC GENERATED FROM MASKED REFINEMENT.
Descriptor:ATP synthase subunit 9, mitochondrial, ATP synthase protein 8, ...
Authors:Srivastava, A.P., Luo, M., Symersky, J., Liao, M.F., Mueller, D.M.
Deposit date:2018-03-13
Release date:2018-04-11
Last modified:2018-05-23
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:High-resolution cryo-EM analysis of the yeast ATP synthase in a lipid membrane.
Science, 360, 2018
2Q6D
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CRYSTAL STRUCTURE OF INFECTIOUS BRONCHITIS VIRUS (IBV) MAIN PROTEASE
Descriptor:Infectious bronchitis virus (IBV) main protease
Authors:Xue, X.Y., Yang, H.T., Xue, F., Bartlam, M., Rao, Z.H.
Deposit date:2007-06-04
Release date:2008-02-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structures of two coronavirus main proteases: implications for substrate binding and antiviral drug design.
J.Virol., 82, 2008
2Q6F
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CRYSTAL STRUCTURE OF INFECTIOUS BRONCHITIS VIRUS (IBV) MAIN PROTEASE IN COMPLEX WITH A MICHAEL ACCEPTOR INHIBITOR N3
Descriptor:Infectious bronchitis virus (IBV) main protease, N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]ALANYL-L-VALYL-N~1~-((1R,2Z)-4-(BENZYLOXY)-4-OXO-1-{[(3R)-2-OXOPYRROLIDIN-3-YL]METHYL}BUT-2-ENYL)-L-LEUCINAMIDE
Authors:Xue, X.Y., Yang, H.T., Xue, F., Bartlam, M., Rao, Z.H.
Deposit date:2007-06-05
Release date:2008-02-12
Last modified:2015-12-02
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of two coronavirus main proteases: implications for substrate binding and antiviral drug design.
J.Virol., 82, 2008
2Q6G
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CRYSTAL STRUCTURE OF SARS-COV MAIN PROTEASE H41A MUTANT IN COMPLEX WITH AN N-TERMINAL SUBSTRATE
Descriptor:severe acute respiratory syndrome coronavirus (SARS-CoV), Polypeptide chain
Authors:Xue, X.Y., Yang, H.T., Xue, F., Bartlam, M., Rao, Z.H.
Deposit date:2007-06-05
Release date:2008-02-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structures of two coronavirus main proteases: implications for substrate binding and antiviral drug design.
J.Virol., 82, 2008
6C5R
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CRYSTAL STRUCTURE OF THE SOLUBLE DOMAIN OF THE MITOCHONDRIAL CALCIUM UNIPORTER
Descriptor:calcium uniporter
Authors:Fan, C., Fan, M., Fastman, N., Zhang, J., Feng, L.
Deposit date:2018-01-16
Release date:2018-07-11
Method:X-RAY DIFFRACTION (3.096083 Å)
Cite:X-ray and cryo-EM structures of the mitochondrial calcium uniporter
Nature, 2018
6C5W
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CRYSTAL STRUCTURE OF THE MITOCHONDRIAL CALCIUM UNIPORTER
Descriptor:calcium uniporter, nanobody, CALCIUM ION
Authors:Fan, C., Fan, M., Fastman, N., Zhang, J., Feng, L.
Deposit date:2018-01-17
Release date:2018-07-11
Method:X-RAY DIFFRACTION (3.100102 Å)
Cite:X-ray and cryo-EM structures of the mitochondrial calcium uniporter
Nature, 2018
6FXN
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CRYSTAL STRUCTURE OF HUMAN BAFF IN COMPLEX WITH FAB FRAGMENT OF ANTI-BAFF ANTIBODY BELIMUMAB
Descriptor:Tumor necrosis factor ligand superfamily member 13B, belimumab heavy chain, belimumab light chain
Authors:Lammens, A., Maskos, K., Willen, L., Jiang, X., Schneider, P.
Deposit date:2018-03-09
Release date:2018-04-04
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:A loop region of BAFF controls B cell survival and regulates recognition by different inhibitors.
Nat Commun, 9, 2018
4W8F
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CRYSTAL STRUCTURE OF THE DYNEIN MOTOR DOMAIN IN THE AMPPNP-BOUND STATE
Descriptor:Dynein heavy chain lysozyme chimera, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, MAGNESIUM ION
Authors:Cheng, H.-C., Bhabha, G., Zhang, N., Vale, R.D.
Deposit date:2014-08-24
Release date:2014-11-12
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (3.541 Å)
Cite:Allosteric communication in the Dynein motor domain.
Cell, 159, 2014
5VAE
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CRYSTAL STRUCTURE OF ACCESSORY SECRETION PROTEIN 1 AND 3
Descriptor:Accessory Sec system protein Asp1, Accessory Sec system protein Asp3
Authors:Chen, Y., Rapoport, T.A., Jeffrey, P.D.
Deposit date:2017-03-25
Release date:2018-02-21
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (3.106 Å)
Cite:Unraveling the sequence of cytosolic reactions in the export of GspB adhesin fromStreptococcus gordonii.
J. Biol. Chem., 293, 2018
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