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1G3G
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NMR STRUCTURE OF THE FHA1 DOMAIN OF YEAST RAD53
Descriptor:PROTIEN KINASE SPK1
Authors:Yuan, C., Liao, H., Su, M., Yongkiettrakul, S., Byeon, I.-J.L., Tsai, M.-D.
Deposit date:2000-10-24
Release date:2001-01-10
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of the FHA1 domain of yeast Rad53 and identification of binding sites for both FHA1 and its target protein Rad9
J.Mol.Biol., 304, 2000
1DMZ
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A REFINED NMR STRUCTURE OF A NEW PHOPHOPEPTIDE-BINDING DOMAIN CONTAINING THE FHA2 OF RAD53
Descriptor:PROTEIN (PROTEIN KINASE SPK1)
Authors:Byeon, I.-J.L., Liao, H., Tsai, M.-D.
Deposit date:1999-12-15
Release date:2000-01-06
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure and Function of a New Phosphopeptide-Binding Domain Containing the Fha2 of Rad53
J.Mol.Biol., 294, 1999
1QU5
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NMR STRUCTURE OF A NEW PHOSPHOTYROSINE BINDING DOMAIN CONTAINING THE FHA2 DOMAIN OF RAD 53
Descriptor:PROTEIN KINASE SPK1
Authors:Byeon, I.-J.L., Liao, H., Tsai, M.-D.
Deposit date:1999-07-06
Release date:1999-12-17
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure and function of a new phosphopeptide-binding domain containing the FHA2 of Rad53.
J.Mol.Biol., 294, 1999
1FHQ
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REFINED SOLUTION STRUCTURE OF THE FHA2 DOMAIN OF RAD53
Descriptor:PROTEIN KINASE SPK1
Authors:Byeon, I.-J.L., Liao, H., Tsai, M.-D.
Deposit date:2000-08-02
Release date:2000-10-18
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:II. Structure and specificity of the interaction between the FHA2 domain of Rad53 and phosphotyrosyl peptides.
J.Mol.Biol., 302, 2000
1FHR
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SOLUTION STRUCTURE OF THE FHA2 DOMAIN OF RAD53 COMPLEXED WITH A PHOSPHOTYROSYL PEPTIDE
Descriptor:PROTEIN KINASE SPK1, DNA REPAIR PROTEIN RAD9
Authors:Byeon, I.-J.L., Liao, H., Yongkiettrakul, S., Tsai, M.-D.
Deposit date:2000-08-02
Release date:2000-10-18
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:II. Structure and specificity of the interaction between the FHA2 domain of Rad53 and phosphotyrosyl peptides.
J.Mol.Biol., 302, 2000
1A8Y
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CRYSTAL STRUCTURE OF CALSEQUESTRIN FROM RABBIT SKELETAL MUSCLE SARCOPLASMIC RETICULUM AT 2.4 A RESOLUTION
Descriptor:CALSEQUESTRIN
Authors:Wang, S., Trumble, W.R., Liao, H., Wesson, C.R., Dunker, A.K., Kang, C.
Deposit date:1998-03-31
Release date:1999-03-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of calsequestrin from rabbit skeletal muscle sarcoplasmic reticulum.
Nat.Struct.Biol., 5, 1998
1YQJ
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CRYSTAL STRUCTURE OF P38 ALPHA IN COMPLEX WITH A SELECTIVE PYRIDAZINE INHIBITOR
Descriptor:Mitogen-activated protein kinase 14, SULFATE ION, 6((S)-3-BENZYLPIPERAZIN-1-YL)-3-(NAPHTHALEN-2-YL)-4-(PYRIDIN-4-YL)PYRAZINE
Authors:Tamayo, N., Liao, H., Goldberg, M., Syed, R., Li, V., Powers, D., Tudor, Y., Yu, V., Wong, M.L., Henkle, B., Middelton, S., Harvey, T., Jang, G., Hungate, R., Dominguez, C.
Deposit date:2005-02-01
Release date:2005-04-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Design and synthesis of potent pyridazine inhibitors of p38 MAP kinase.
Bioorg.Med.Chem.Lett., 15, 2005
4N0T
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CORE STRUCTURE OF THE U6 SMALL NUCLEAR RIBONUCLEOPROTEIN AT 1.7 ANGSTROM RESOLUTION
Descriptor:U4/U6 snRNA-associated-splicing factor PRP24, U6 snRNA, SULFATE ION
Authors:Montemayor, E.J., Curran, E.C., Liao, H., Andrews, K.L., Treba, C.N., Butcher, S.E., Brow, D.A.
Deposit date:2013-10-02
Release date:2014-05-14
Last modified:2014-07-02
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Core structure of the U6 small nuclear ribonucleoprotein at 1.7- angstrom resolution.
Nat.Struct.Mol.Biol., 21, 2014
4V6N
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STRUCTURAL CHARACTERIZATION OF MRNA-TRNA TRANSLOCATION INTERMEDIATES (50S RIBOSOME OF CLASS2 OF THE SIX CLASSES)
Descriptor:5S ribosomal RNA, 23S ribosomal RNA, 50S ribosomal protein L1, ...
Authors:Agirrezabala, X., Liao, H., Schreiner, E., Fu, J., Ortiz-Meoz, R.F., Schulten, K., Green, R., Frank, J.
Deposit date:2011-12-07
Release date:2014-07-09
Last modified:2019-07-03
Method:ELECTRON MICROSCOPY (12.1 Å)
Cite:Structural characterization of mRNA-tRNA translocation intermediates.
Proc.Natl.Acad.Sci.USA, 109, 2012
4V6O
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STRUCTURAL CHARACTERIZATION OF MRNA-TRNA TRANSLOCATION INTERMEDIATES (CLASS 4A OF THE SIX CLASSES)
Descriptor:16S ribosomal RNA, A site tRNA, mRNA, ...
Authors:Agirrezabala, X., Liao, H., Schreiner, E., Fu, J., Ortiz-Meoz, R.F., Schulten, K., Green, R., Frank, J.
Deposit date:2011-12-07
Release date:2014-07-09
Last modified:2019-07-03
Method:ELECTRON MICROSCOPY (14.7 Å)
Cite:Structural characterization of mRNA-tRNA translocation intermediates.
Proc.Natl.Acad.Sci.USA, 109, 2012
4V6P
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STRUCTURAL CHARACTERIZATION OF MRNA-TRNA TRANSLOCATION INTERMEDIATES (CLASS 4B OF THE SIX CLASSES)
Descriptor:16S ribosomal RNA, A site tRNA, mRNA, ...
Authors:Agirrezabala, X., Liao, H., Schreiner, E., Fu, J., Ortiz-Meoz, R.F., Schulten, K., Green, R., Frank, J.
Deposit date:2011-12-08
Release date:2014-07-09
Last modified:2019-07-03
Method:ELECTRON MICROSCOPY (13.5 Å)
Cite:Structural characterization of mRNA-tRNA translocation intermediates.
Proc.Natl.Acad.Sci.USA, 109, 2012
4V6Q
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STRUCTURAL CHARACTERIZATION OF MRNA-TRNA TRANSLOCATION INTERMEDIATES (CLASS 5 OF THE SIX CLASSES)
Descriptor:16S ribosomal RNA, A site tRNA, mRNA, ...
Authors:Agirrezabala, X., Liao, H., Schreiner, E., Fu, J., Ortiz-Meoz, R.F., Schulten, K., Green, R., Frank, J.
Deposit date:2011-12-08
Release date:2014-07-09
Last modified:2019-07-03
Method:ELECTRON MICROSCOPY (11.5 Å)
Cite:Structural characterization of mRNA-tRNA translocation intermediates.
Proc.Natl.Acad.Sci.USA, 109, 2012
4V6R
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STRUCTURAL CHARACTERIZATION OF MRNA-TRNA TRANSLOCATION INTERMEDIATES (CLASS 6 OF THE SIX CLASSES)
Descriptor:16S ribosomal RNA, A site tRNA, mRNA, ...
Authors:Agirrezabala, X., Liao, H., Schreiner, E., Fu, J., Ortiz-Meoz, R.F., Schulten, K., Green, R., Frank, J.
Deposit date:2011-12-08
Release date:2014-07-09
Last modified:2019-07-03
Method:ELECTRON MICROSCOPY (11.5 Å)
Cite:Structural characterization of mRNA-tRNA translocation intermediates.
Proc.Natl.Acad.Sci.USA, 109, 2012
4V6S
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STRUCTURAL CHARACTERIZATION OF MRNA-TRNA TRANSLOCATION INTERMEDIATES (CLASS 3 OF THE SIX CLASSES)
Descriptor:5S ribomosomal RNA, 23S ribomosomal RNA, 50S ribosomal protein L1, ...
Authors:Agirrezabala, X., Liao, H., Schreiner, E., Fu, J., Ortiz-Meoz, R.F., Schulten, K., Green, R., Frank, J.
Deposit date:2011-12-09
Release date:2014-07-09
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (13.1 Å)
Cite:Structural characterization of mRNA-tRNA translocation intermediates.
Proc.Natl.Acad.Sci.USA, 109, 2012
1J4K
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SOLUTION STRUCTURE OF THE FHA2 DOMAIN OF RAD53 COMPLEXED WITH A PHOSPHOTYROSYL PEPTIDE DERIVED FROM RAD9
Descriptor:PROTEIN KINASE SPK1, DNA REPAIR PROTEIN RAD9
Authors:Byeon, I.-J.L., Yongkiettrakul, S., Tsai, M.-D.
Deposit date:2001-10-03
Release date:2001-12-05
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the yeast Rad53 FHA2 complexed with a phosphothreonine peptide pTXXL: comparison with the structures of FHA2-pYXL and FHA1-pTXXD complexes.
J.Mol.Biol., 314, 2001
1J4L
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SOLUTION STRUCTURE OF THE FHA2 DOMAIN OF RAD53 COMPLEXED WITH A PHOSPHOTHREONYL PEPTIDE DERIVED FROM RAD9
Descriptor:PROTEIN KINASE SPK1, DNA REPAIR PROTEIN RAD9
Authors:Byeon, I.-J.L., Yongkiettrakul, S., Tsai, M.-D.
Deposit date:2001-10-03
Release date:2001-12-05
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the yeast Rad53 FHA2 complexed with a phosphothreonine peptide pTXXL: comparison with the structures of FHA2-pYXL and FHA1-pTXXD complexes.
J.Mol.Biol., 314, 2001
1K2M
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SOLUTION STRUCTURE OF THE FHA2 DOMAIN OF RAD53 COMPLEXED WITH A PHOSPHOTYROSYL PEPTIDE DERIVED FROM RAD9
Descriptor:Protein Kinase SPK1, DNA repair protein Rad9
Authors:Byeon, I.-J.L., Yongkiettrakul, S., Tsai, M.-D.
Deposit date:2001-09-28
Release date:2001-12-05
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the yeast Rad53 FHA2 complexed with a phosphothreonine peptide pTXXL: comparison with the structures of FHA2-pYXL and FHA1-pTXXD complexes.
J.Mol.Biol., 314, 2001
1K2N
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SOLUTION STRUCTURE OF THE FHA2 DOMAIN OF RAD53 COMPLEXED WITH A PHOSPHOTHREONYL PEPTIDE DERIVED FROM RAD9
Descriptor:Protein Kinase SPK1, DNA repair protein Rad9
Authors:Byeon, I.-J.L., Yongkiettrakul, S., Tsai, M.-D.
Deposit date:2001-09-28
Release date:2001-12-05
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the yeast Rad53 FHA2 complexed with a phosphothreonine peptide pTXXL: comparison with the structures of FHA2-pYXL and FHA1-pTXXD complexes.
J.Mol.Biol., 314, 2001
3GZN
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STRUCTURE OF NEDD8-ACTIVATING ENZYME IN COMPLEX WITH NEDD8 AND MLN4924
Descriptor:NEDD8-activating enzyme E1 regulatory subunit, NEDD8-activating enzyme E1 catalytic subunit, NEDD8, ...
Authors:Sintchak, M.D.
Deposit date:2009-04-07
Release date:2010-02-02
Last modified:2012-03-21
Method:X-RAY DIFFRACTION (3 Å)
Cite:Substrate-assisted inhibition of ubiquitin-like protein-activating enzymes: the NEDD8 E1 inhibitor MLN4924 forms a NEDD8-AMP mimetic in situ.
Mol.Cell, 37, 2010
3S2A
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CRYSTAL STRUCTURE OF PI3K-GAMMA IN COMPLEX WITH A QUINOLINE INHIBITOR
Descriptor:Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, SULFATE ION, N-{2-chloro-5-[4-(morpholin-4-yl)quinolin-6-yl]pyridin-3-yl}-4-fluorobenzenesulfonamide
Authors:Whittington, D.A., Tang, J., Yakowec, P.
Deposit date:2011-05-16
Release date:2011-06-08
Last modified:2011-07-20
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Phospshoinositide 3-Kinase (PI3K)/Mammalian Target of Rapamycin (mTOR) Dual Inhibitors: Discovery and Structure-Activity Relationships of a Series of Quinoline and Quinoxaline Derivatives.
J.Med.Chem., 54, 2011
5TF6
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STRUCTURE AND CONFORMATIONAL PLASTICITY OF THE U6 SMALL NUCLEAR RIBONUCLEOPROTEIN CORE
Descriptor:U4/U6 snRNA-associated-splicing factor PRP24, U6 snRNA, POTASSIUM ION, ...
Authors:Montemayor, E.J., Brow, D.A., Butcher, S.E.
Deposit date:2016-09-24
Release date:2017-01-11
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure and conformational plasticity of the U6 small nuclear ribonucleoprotein core.
Acta Crystallogr D Struct Biol, 73, 2017
1J4P
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NMR STRUCTURE OF THE FHA1 DOMAIN OF RAD53 IN COMPLEX WITH A RAD9-DERIVED PHOSPHOTHREONINE (AT T155) PEPTIDE
Descriptor:PROTEIN KINASE SPK1, DNA REPAIR PROTEIN RAD9
Authors:Yuan, C., Yongkiettrakul, S., Byeon, I.-J.L., Zhou, S., Tsai, M.-D.
Deposit date:2001-10-22
Release date:2001-12-05
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structures of two FHA1-phosphothreonine peptide complexes provide insight into the structural basis of the ligand specificity of FHA1 from yeast Rad53.
J.Mol.Biol., 314, 2001
1J4Q
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NMR STRUCTURE OF THE FHA1 DOMAIN OF RAD53 IN COMPLEX WITH A RAD9-DERIVED PHOSPHOTHREONINE (AT T192) PEPTIDE
Descriptor:PROTEIN KINASE SPK1, DNA REPAIR PROTEIN RAD9
Authors:Yuan, C., Yongkiettrakul, S., Byeon, I.-J.L., Zhou, S., Tsai, M.-D.
Deposit date:2001-10-22
Release date:2001-12-05
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structures of two FHA1-phosphothreonine peptide complexes provide insight into the structural basis of the ligand specificity of FHA1 from yeast Rad53.
J.Mol.Biol., 314, 2001
1K3N
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NMR STRUCTURE OF THE FHA1 DOMAIN OF RAD53 IN COMPLEX WITH A RAD9-DERIVED PHOSPHOTHREONINE (AT T155) PEPTIDE
Descriptor:Protein Kinase SPK1, DNA repair protein Rad9
Authors:Yuan, C., Yongkiettrakul, S., Byeon, I.-J.L., Zhou, S., Tsai, M.-D.
Deposit date:2001-10-03
Release date:2001-12-05
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structures of two FHA1-phosphothreonine peptide complexes provide insight into the structural basis of the ligand specificity of FHA1 from yeast Rad53.
J.Mol.Biol., 314, 2001
1K3Q
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NMR STRUCTURE OF THE FHA1 DOMAIN OF RAD53 IN COMPLEX WITH A RAD9-DERIVED PHOSPHOTHREONINE (AT T192) PEPTIDE
Descriptor:Protein Kinase SPK1, DNA repair protein Rad9
Authors:Yuan, C., Yongkiettrakul, S., Byeon, I.-J.L., Zhou, S., Tsai, M.-D.
Deposit date:2001-10-03
Release date:2001-12-05
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structures of two FHA1-phosphothreonine peptide complexes provide insight into the structural basis of the ligand specificity of FHA1 from yeast Rad53.
J.Mol.Biol., 314, 2001