Author results

1HV4
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CRYSTAL STRUCTURE ANALYSIS OF BAR-HEAD GOOSE HEMOGLOBIN (DEOXY FORM)
Descriptor:HEMOGLOBIN ALPHA-A CHAIN, HEMOGLOBIN BETA CHAIN, PROTOPORPHYRIN IX CONTAINING FE
Authors:Liang, Y., Hua, Z., Liang, X., Xu, Q., Lu, G.
Deposit date:2001-01-07
Release date:2001-01-17
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The crystal structure of bar-headed goose hemoglobin in deoxy form: the allosteric mechanism of a hemoglobin species with high oxygen affinity.
J.Mol.Biol., 313, 2001
4MMJ
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CRYSTAL STRUCTURE OF YAFQ FROM E.COLI STRAIN BL21(DE3)
Descriptor:Addiction module toxin, RelE/StbE family, SULFATE ION
Authors:Liang, Y., Gao, Z., Liu, Q., Dong, Y.
Deposit date:2013-09-09
Release date:2014-06-25
Last modified:2018-10-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural and Functional Characterization of Escherichia coli Toxin-Antitoxin Complex DinJ-YafQ
J.Biol.Chem., 289, 2014
4E6S
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CRYSTAL STRUCTURE OF THE SCAN DOMAIN FROM MOUSE ZFP206
Descriptor:Zinc finger and SCAN domain-containing protein 10
Authors:Liang, Y., Choo, S.H., Rossbach, M., Baburajendran, N., Palasingam, P., Kolatkar, P.R.
Deposit date:2012-03-15
Release date:2012-05-02
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal optimization and preliminary diffraction data analysis of the SCAN domain of Zfp206.
Acta Crystallogr.,Sect.F, 68, 2012
6DDT
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MOUSE BETA-MANNOSIDASE (MANBA)
Descriptor:Beta-mannosidase, CALCIUM ION, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Gytz, H., Liang, J., Liang, Y., Gorelik, A., Illes, K., Nagar, B.
Deposit date:2018-05-10
Release date:2019-01-09
Last modified:2019-04-17
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The structure of mammalian beta-mannosidase provides insight into beta-mannosidosis and nystagmus.
FEBS J., 286, 2019
6DDU
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MOUSE BETA-MANNOSIDASE BOUND TO BETA-D-MANNOSE (MANBA)
Descriptor:Beta-mannosidase, CALCIUM ION, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Gytz, H., Liang, J., Liang, Y., Gorelik, A., Illes, K., Nagar, B.
Deposit date:2018-05-10
Release date:2019-01-09
Last modified:2019-04-17
Method:X-RAY DIFFRACTION (2.668 Å)
Cite:The structure of mammalian beta-mannosidase provides insight into beta-mannosidosis and nystagmus.
FEBS J., 286, 2019
1RKB
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THE STRUCTURE OF ADRENAL GLAND PROTEIN AD-004
Descriptor:Protein AD-004, SULFATE ION, LITHIUM ION
Authors:Ren, H., Liang, Y., Bennett, M., Su, X.D.
Deposit date:2003-11-21
Release date:2005-01-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The crystal structure of human adenylate kinase 6: An adenylate kinase localized to the cell nucleus
Proc.Natl.Acad.Sci.Usa, 102, 2005
1YFZ
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NOVEL IMP BINDING IN FEEDBACK INHIBITION OF HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE FROM THERMOANAEROBACTER TENGCONGENSIS
Descriptor:Hypoxanthine-guanine phosphoribosyltransferase, ACETATE ION, MAGNESIUM ION, ...
Authors:Chen, Q., Liang, Y., Su, X., Gu, X., Zheng, X., Luo, M.
Deposit date:2005-01-04
Release date:2005-05-10
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Alternative IMP Binding in Feedback Inhibition of Hypoxanthine-Guanine Phosphoribosyltransferase from Thermoanaerobacter tengcongensis.
J.Mol.Biol., 348, 2005
3MWP
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NUCLEOPROTEIN STRUCTURE OF LASSA FEVER VIRUS
Descriptor:Nucleoprotein, ZINC ION
Authors:Qi, X., Lan, S., Wang, W., Schelde, L.M., Dong, H., Wallat, G., Liang, Y., Ly, H., Dong, C., Scottish Structural Proteomics Facility (SSPF)
Deposit date:2010-05-06
Release date:2010-12-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.795 Å)
Cite:Cap binding and immune evasion revealed by Lassa nucleoprotein structure.
Nature, 468, 2010
3MWT
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CRYSTAL STRUCTURE OF LASSA FEVER VIRUS NUCLEOPROTEIN IN COMPLEX WITH MN2+
Descriptor:Nucleoprotein, MANGANESE (II) ION, ZINC ION
Authors:Qi, X., Lan, S., Wang, W., Schelde, L.M., Dong, H., Wallat, G., Liang, Y., Ly, H., Dong, C., Scottish Structural Proteomics Facility (SSPF)
Deposit date:2010-05-06
Release date:2010-12-01
Last modified:2014-12-10
Method:X-RAY DIFFRACTION (1.982 Å)
Cite:Cap binding and immune evasion revealed by Lassa nucleoprotein structure.
Nature, 468, 2010
3MX2
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LASSA FEVER VIRUS NUCLEOPROTEIN COMPLEXED WITH DTTP
Descriptor:Nucleoprotein, THYMIDINE-5'-TRIPHOSPHATE, ZINC ION
Authors:Qi, X., Lan, S., Wang, W., Schelde, L.M., Dong, H., Wallat, G., Liang, Y., Ly, H., Dong, C., Scottish Structural Proteomics Facility (SSPF)
Deposit date:2010-05-06
Release date:2010-12-01
Last modified:2011-08-10
Method:X-RAY DIFFRACTION (1.983 Å)
Cite:Cap binding and immune evasion revealed by Lassa nucleoprotein structure.
Nature, 468, 2010
3MX5
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LASSA FEVER VIRUS NUCLEOPROTEIN COMPLEXED WITH UTP
Descriptor:Nucleoprotein, URIDINE 5'-TRIPHOSPHATE, ZINC ION
Authors:Qi, X., Lan, S., Wang, W., Schelde, L.M., Dong, H., Wallat, G., Liang, Y., Ly, H., Dong, C., Scottish Structural Proteomics Facility (SSPF)
Deposit date:2010-05-06
Release date:2010-12-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.903 Å)
Cite:Cap binding and immune evasion revealed by Lassa nucleoprotein structure.
Nature, 468, 2010
4G9Z
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LASSA NUCLEOPROTEIN WITH DSRNA REVEALS NOVEL MECHANISM FOR IMMUNE SUPPRESSION
Descriptor:RNA (5'-R(P*GP*CP*CP*C)-3'), RNA (5'-R(P*GP*GP*GP*C)-3'), Nucleoprotein, ...
Authors:Jiang, X., Huang, Q., Wang, W., Dong, H., Ly, H., Liang, Y., Dong, C., Scottish Structural Proteomics Facility (SSPF)
Deposit date:2012-07-24
Release date:2013-04-03
Last modified:2013-07-24
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Structures of Arenaviral Nucleoproteins with Triphosphate dsRNA Reveal a Unique Mechanism of Immune Suppression.
J.Biol.Chem., 288, 2013
4GV3
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STRUCTURES OF LASSA AND TACARIBE VIRAL NUCLEOPROTEINS WITH OR WITHOUT 5 TRIPHOSPHATE DSRNA SUBSTRATE REVEAL A UNIQUE 3 -5 EXORIBONUCLEASE MECHANISM TO SUPPRESS TYPE I INTERFERON PRODUCTION
Descriptor:RNA (5'-R(*(GTP)P*GP*GP*C)-3'), RNA (5'-R(P*CP*GP*CP*CP*C)-3'), Nucleoprotein, ...
Authors:Jiang, X., Huang, Q., Wang, W., Dong, H., Ly, H., Liang, Y., Dong, C.
Deposit date:2012-08-30
Release date:2013-05-01
Last modified:2013-07-10
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Structures of Arenaviral Nucleoproteins with Triphosphate dsRNA Reveal a Unique Mechanism of Immune Suppression.
J.Biol.Chem., 288, 2013
4GV6
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STRUCTURES OF LASSA AND TACARIBE VIRAL NUCLEOPROTEINS WITH OR WITHOUT 5 TRIPHOSPHATE DSRNA SUBSTRATE REVEAL A UNIQUE 3 -5 EXORIBONUCLEASE MECHANISM TO SUPPRESS TYPE I INTERFERON PRODUCTION
Descriptor:RNA (5'-R(*(GTP)P*GP*GP*C)-3'), RNA (5'-R(P*CP*GP*CP*CP*C)-3'), Nucleoprotein, ...
Authors:Jiang, X., Huang, Q., Wang, W., Dong, H., Ly, H., Liang, Y., Dong, C.
Deposit date:2012-08-30
Release date:2013-05-01
Last modified:2013-07-10
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Structures of Arenaviral Nucleoproteins with Triphosphate dsRNA Reveal a Unique Mechanism of Immune Suppression.
J.Biol.Chem., 288, 2013
4GV9
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LASSA NUCLEOPROTEIN C-TERMINAL DOMAIN IN COMPLEX WITH TRIPHOSPHATED DSRNA SOAKING FOR 5 MIN
Descriptor:RNA (5'-R(*(GTP)P*GP*GP*C)-3'), RNA (5'-R(P*CP*GP*CP*CP*C)-3'), Nucleoprotein, ...
Authors:Jiang, X., Huang, Q., Wang, W., Dong, H., Ly, H., Liang, Y., Dong, C.
Deposit date:2012-08-30
Release date:2013-05-01
Last modified:2013-07-10
Method:X-RAY DIFFRACTION (2.46 Å)
Cite:Structures of Arenaviral Nucleoproteins with Triphosphate dsRNA Reveal a Unique Mechanism of Immune Suppression.
J.Biol.Chem., 288, 2013
4GVE
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TACARIBE NUCLEOPROTEIN STRUCTURE
Descriptor:Nucleoprotein, ZINC ION, MAGNESIUM ION
Authors:Jiang, X., Huang, Q., Wang, W., Dong, H., Ly, H., Liang, Y., Dong, C.
Deposit date:2012-08-30
Release date:2013-05-01
Last modified:2013-07-10
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Structures of Arenaviral Nucleoproteins with Triphosphate dsRNA Reveal a Unique Mechanism of Immune Suppression.
J.Biol.Chem., 288, 2013
4MIW
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HIGH-RESOLUTION STRUCTURE OF THE N-TERMINAL ENDONUCLEASE DOMAIN OF THE LASSA VIRUS L POLYMERASE
Descriptor:RNA-directed RNA polymerase L, MAGNESIUM ION
Authors:Wallat, G.D., Huang, Q., Wang, W., Dong, H., Ly, H., Liang, Y., Dong, C.
Deposit date:2013-09-02
Release date:2014-03-19
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:High-resolution structure of the N-terminal endonuclease domain of the lassa virus L polymerase in complex with magnesium ions.
Plos One, 9, 2014
4ML0
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CRYSTAL STRUCTURE OF E.COLI DINJ-YAFQ COMPLEX
Descriptor:Predicted antitoxin of YafQ-DinJ toxin-antitoxin system, Predicted toxin of the YafQ-DinJ toxin-antitoxin system, SULFATE ION
Authors:Liang, Y.J., Gao, Z.Q., Liu, Q.S., Dong, Y.H.
Deposit date:2013-09-06
Release date:2014-06-25
Last modified:2014-08-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and Functional Characterization of Escherichia coli Toxin-Antitoxin Complex DinJ-YafQ
J.Biol.Chem., 289, 2014
4ML2
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CRYSTAL STRUCTURE OF WILD-TYPE YAFQ
Descriptor:mRNA interferase YafQ, SULFATE ION
Authors:Liang, Y.J., Gao, Z.Q., Liu, Q.S., Dong, Y.H.
Deposit date:2013-09-06
Release date:2014-06-25
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural and Functional Characterization of Escherichia coli Toxin-Antitoxin Complex DinJ-YafQ
J.Biol.Chem., 289, 2014
4MMG
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CRYSTAL STRUCTURE OF YAFQ MUTANT H87Q FROM E.COLI
Descriptor:mRNA interferase YafQ, SULFATE ION
Authors:Liang, Y.J., Gao, Z.Q., Liu, Q.S., Dong, Y.H.
Deposit date:2013-09-09
Release date:2014-06-25
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural and Functional Characterization of Escherichia coli Toxin-Antitoxin Complex DinJ-YafQ
J.Biol.Chem., 289, 2014
4IRE
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CRYSTAL STRUCTURE OF GLIC WITH MUTATIONS AT THE LOOP C REGION
Descriptor:Proton-gated ion channel, tetradecyl 4-O-alpha-D-glucopyranosyl-beta-D-glucopyranoside, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ...
Authors:Chen, Q., Pan, J., Liang, Y.H., Xu, Y., Tang, P.
Deposit date:2013-01-14
Release date:2013-04-24
Last modified:2013-05-22
Method:X-RAY DIFFRACTION (3.19 Å)
Cite:Signal transduction pathways in the pentameric ligand-gated ion channels.
Plos One, 8, 2013
5GON
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STRUCTURES OF A BETA-LACTAM BRIDGED ANALOGUE IN COMPLEX WITH TUBULIN
Descriptor:Tubulin alpha-1B chain, Tubulin beta-2B chain, Stathmin-4, ...
Authors:Zhou, L., Liu, Y., Cheng, L., Wang, Y.
Deposit date:2016-07-28
Release date:2017-03-22
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Potent Antitumor Activities and Structure Basis of the Chiral beta-Lactam Bridged Analogue of Combretastatin A-4 Binding to Tubulin.
J. Med. Chem., 59, 2016
3R24
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CRYSTAL STRUCTURE OF NSP10/NSP16 COMPLEX OF SARS CORONAVIRUS" IF POSSIBLE
Descriptor:2'-O-methyl transferase, Non-structural protein 10 and Non-structural protein 11, S-ADENOSYLMETHIONINE, ...
Authors:Liu, X., Guo, D., Su, C., Chen, Y.
Deposit date:2011-03-13
Release date:2011-10-26
Last modified:2013-01-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:Biochemical and structural insights into the mechanisms of SARS coronavirus RNA ribose 2'-O-methylation by nsp16/nsp10 protein complex.
Plos Pathog., 7, 2011
5GS4
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CRYSTAL STRUCTURE OF ESTROGEN RECEPTOR ALPHA IN COMPLEX WITH A STABILIZED PEPTIDE ANTAGONIST
Descriptor:Estrogen receptor, ARG-IAS-ILE-LEU-DNP-ARG-LEU-LEU-GLN, PHOSPHATE ION, ...
Authors:Xie, M., Wang, T., Li, Z.-G.
Deposit date:2016-08-13
Release date:2017-08-30
Last modified:2018-07-18
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural Basis of Inhibition of ER alpha-Coactivator Interaction by High-Affinity N-Terminus Isoaspartic Acid Tethered Helical Peptides
J. Med. Chem., 60, 2017
5GTR
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ESTROGEN RECEPTOR ALPHA IN COMPLEX WITH A STABILIZED PEPTIDE ANTAGONIST 6
Descriptor:Estrogen receptor, ARG-IAS-ILE-0JY-DPP-ARG-0JY-0JY-GLN-NH2, ESTRADIOL
Authors:Xie, M., Wang, T., Li, Z.-G.
Deposit date:2016-08-23
Release date:2017-08-30
Last modified:2017-12-20
Method:X-RAY DIFFRACTION (2.804 Å)
Cite:Structural Basis of Inhibition of ER alpha-Coactivator Interaction by High-Affinity N-Terminus Isoaspartic Acid Tethered Helical Peptides
J. Med. Chem., 60, 2017
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