Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
1ZCK
DownloadVisualize
BU of 1zck by Molmil
native structure prl-1 (ptp4a1)
Descriptor: ACETIC ACID, protein tyrosine phosphatase 4a1
Authors:Sun, J.P, Wang, W.Q, Yang, H, Liu, S, Liang, F, Fedorov, A.A, Almo, S.C, Zhang, Z.Y.
Deposit date:2005-04-12
Release date:2005-09-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure and Biochemical Properties of PRL-1, a Phosphatase Implicated in Cell Growth, Differentiation, and Tumor Invasion.
Biochemistry, 44, 2005
1ZCL
DownloadVisualize
BU of 1zcl by Molmil
prl-1 c104s mutant in complex with sulfate
Descriptor: SULFATE ION, protein tyrosine phosphatase 4a1
Authors:Sun, J.P, Wang, W.Q, Yang, H, Liu, S, Liang, F, Fedorov, A.A, Almo, S.C, Zhang, Z.Y.
Deposit date:2005-04-12
Release date:2005-09-20
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure and Biochemical Properties of PRL-1, a Phosphatase Implicated in Cell Growth, Differentiation, and Tumor Invasion.
Biochemistry, 44, 2005
6TCZ
DownloadVisualize
BU of 6tcz by Molmil
Leishmania tarentolae proteasome 20S subunit complexed with LXE408
Descriptor: Proteasome endopeptidase complex, Proteasome subunit alpha type, Proteasome subunit beta, ...
Authors:Srinivas, H.
Deposit date:2019-11-07
Release date:2020-08-26
Last modified:2020-10-21
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Discovery and Characterization of Clinical Candidate LXE408 as a Kinetoplastid-Selective Proteasome Inhibitor for the Treatment of Leishmaniases.
J.Med.Chem., 63, 2020
6TD5
DownloadVisualize
BU of 6td5 by Molmil
Leishmania tarentolae proteasome 20S subunit complexed with LXE408 and bortezomib
Descriptor: N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE, Proteasome endopeptidase complex, Proteasome subunit alpha type, ...
Authors:Srinivas, H.
Deposit date:2019-11-07
Release date:2020-08-26
Last modified:2020-10-21
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Discovery and Characterization of Clinical Candidate LXE408 as a Kinetoplastid-Selective Proteasome Inhibitor for the Treatment of Leishmaniases.
J.Med.Chem., 63, 2020
5U5H
DownloadVisualize
BU of 5u5h by Molmil
Crystal structure of EED in complex with 6-(2-fluoro-5-methoxybenzyl)-1-isopropyl-5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-3-amine 6-(2-fluoro-5-methoxybenzyl)-1-isopropyl-5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-3-amine
Descriptor: (6S)-6-[(2-fluoro-5-methoxyphenyl)methyl]-1-(propan-2-yl)-5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-3-amine, GLYCEROL, Polycomb protein EED
Authors:Bussiere, D, Shu, W.
Deposit date:2016-12-06
Release date:2017-01-11
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure-Guided Design of EED Binders Allosterically Inhibiting the Epigenetic Polycomb Repressive Complex 2 (PRC2) Methyltransferase.
J. Med. Chem., 60, 2017
5U62
DownloadVisualize
BU of 5u62 by Molmil
Crystal structure of EED in complex with H3K27Me3 peptide and 6-(benzo[d][1,3]dioxol-4-ylmethyl)-5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-3-amine
Descriptor: (6S)-6-[(2H-1,3-benzodioxol-4-yl)methyl]-5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-3-amine, GLYCEROL, Histone-lysine N-methyltransferase EZH2, ...
Authors:Bussiere, D, Shu, W.
Deposit date:2016-12-07
Release date:2017-01-11
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure-Guided Design of EED Binders Allosterically Inhibiting the Epigenetic Polycomb Repressive Complex 2 (PRC2) Methyltransferase.
J. Med. Chem., 60, 2017
5U5T
DownloadVisualize
BU of 5u5t by Molmil
Crystal structure of EED in complex with H3K27Me3 peptide and 3-(benzo[d][1,3]dioxol-4-ylmethyl)piperidine-1-carboximidamide
Descriptor: (3R)-3-[(2H-1,3-benzodioxol-4-yl)methyl]piperidine-1-carboximidamide, Histone-lysine N-methyltransferase EZH2, Polycomb protein EED, ...
Authors:Bussiere, D, Shu, W.
Deposit date:2016-12-07
Release date:2017-01-11
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure-Guided Design of EED Binders Allosterically Inhibiting the Epigenetic Polycomb Repressive Complex 2 (PRC2) Methyltransferase.
J. Med. Chem., 60, 2017
5U5K
DownloadVisualize
BU of 5u5k by Molmil
Crystal structure of EED in complex with 3-(3-methoxybenzyl)piperidine hydrochloride
Descriptor: (3R)-3-[(3-methoxyphenyl)methyl]piperidine, FORMIC ACID, Polycomb protein EED
Authors:Bussiere, D, Shu, W.
Deposit date:2016-12-06
Release date:2017-01-11
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:Structure-Guided Design of EED Binders Allosterically Inhibiting the Epigenetic Polycomb Repressive Complex 2 (PRC2) Methyltransferase.
J. Med. Chem., 60, 2017
1X24
DownloadVisualize
BU of 1x24 by Molmil
Prl-1 (ptp4a)
Descriptor: protein tyrosine phosphatase 4a1
Authors:Zhang, Z.Y, Sun, J.P, Liu, S, Wang, W.Q, Yang, H.
Deposit date:2005-04-20
Release date:2005-10-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structure and Biochemical Properties of PRL-1, a Phosphatase Implicated in Cell Growth, Differentiation, and Tumor Invasion(,)
Biochemistry, 44, 2005
4QND
DownloadVisualize
BU of 4qnd by Molmil
Crystal structure of a SemiSWEET
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, Chemical transport protein, ...
Authors:Yan, X, Yuyong, T, Liang, F, Perry, K.
Deposit date:2014-06-17
Release date:2014-09-10
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.698 Å)
Cite:Structures of bacterial homologues of SWEET transporters in two distinct conformations.
Nature, 515, 2014
4QNC
DownloadVisualize
BU of 4qnc by Molmil
Crystal structure of a SemiSWEET in an occluded state
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, PENTADECANE, chemical transport protein
Authors:Yan, X, Yuyong, T, Liang, F, Perry, K.
Deposit date:2014-06-17
Release date:2014-09-10
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.388 Å)
Cite:Structures of bacterial homologues of SWEET transporters in two distinct conformations.
Nature, 515, 2014

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon