Author results

2AJF
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STRUCTURE OF SARS CORONAVIRUS SPIKE RECEPTOR-BINDING DOMAIN COMPLEXED WITH ITS RECEPTOR
Descriptor:Angiotensin-converting enzyme-Related Carboxypeptidase (Ace2), SARS-coronavirus spike protein, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Li, F., Li, W., Farzan, M., Harrison, S.C.
Deposit date:2005-08-01
Release date:2005-09-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure of SARS coronavirus spike receptor-binding domain complexed with receptor.
Science, 309, 2005
3UIU
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CRYSTAL STRUCTURE OF APO-PKR KINASE DOMAIN
Descriptor:Interferon-induced, double-stranded RNA-activated protein kinase
Authors:Li, F., Li, S., Yang, X., Shen, Y., Zhang, T.
Deposit date:2011-11-06
Release date:2012-11-07
Method:X-RAY DIFFRACTION (2.903 Å)
Cite:Crystal structure of Apo-PKR kinase domain
TO BE PUBLISHED
1MIV
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CRYSTAL STRUCTURE OF BACILLUS STEAROTHERMOPHILUS CCA-ADDING ENZYME
Descriptor:tRNA CCA-adding enzyme, MAGNESIUM ION
Authors:Li, F., Xiong, Y., Wang, J., Cho, H.D., Weiner, A.M., Steitz, T.A.
Deposit date:2002-08-23
Release date:2002-12-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Crystal structures of the Bacillus stearothermophilus CCA-adding enzyme and its complexes with ATP or CTP
Cell(Cambridge,Mass.), 111, 2002
1MIW
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CRYSTAL STRUCTURE OF BACILLUS STEAROTHERMOPHILUS CCA-ADDING ENZYME IN COMPLEX WITH ATP
Descriptor:tRNA CCA-adding enzyme, MAGNESIUM ION, ADENOSINE-5'-TRIPHOSPHATE
Authors:Li, F., Xiong, Y., Wang, J., Cho, H.D., Weiner, A.M., Steitz, T.A.
Deposit date:2002-08-23
Release date:2002-12-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structures of the Bacillus stearothermophilus CCA-adding enzyme and its complexes with ATP or CTP
Cell(Cambridge,Mass.), 111, 2002
1MIY
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CRYSTAL STRUCTURE OF BACILLUS STEAROTHERMOPHILUS CCA-ADDING ENZYME IN COMPLEX WITH CTP
Descriptor:tRNA CCA-adding enzyme, MAGNESIUM ION, CYTIDINE-5'-TRIPHOSPHATE
Authors:Li, F., Xiong, Y., Wang, J., Cho, H.D., Weiner, A.M., Steitz, T.A.
Deposit date:2002-08-23
Release date:2002-12-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.52 Å)
Cite:Crystal structures of the Bacillus stearothermophilus CCA-adding enzyme and its complexes with ATP or CTP
Cell(Cambridge,Mass.), 111, 2002
2Q1O
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CRYSTAL STRUCTURE ANALYSIS OF THE RNA DODECAMER CGC-NF2-AAUUGGCG, WITH AN INCORPORATED 2,4-DIFLUOROTOLUYL RESIDUE (NF2)
Descriptor:RNA (5'-R(*CP*GP*CP*(NF2)P*AP*AP*UP*UP*GP*GP*CP*G)-3')
Authors:Li, F., Pallan, P.S.
Deposit date:2007-05-25
Release date:2007-10-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Crystal structure, stability and in vitro RNAi activity of oligoribonucleotides containing the ribo-difluorotoluyl nucleotide: insights into substrate requirements by the human RISC Ago2 enzyme.
Nucleic Acids Res., 35, 2007
2Q1R
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CRYSTAL STRUCTURE ANALYSIS OF THE RNA DODECAMER CGCGAAUUAGCG, WITH A G-A MISMATCH.
Descriptor:RNA (5'-R(*CP*GP*CP*GP*AP*AP*UP*UP*AP*GP*CP*G)-3'), MAGNESIUM ION
Authors:Li, F., Pallan, P.S.
Deposit date:2007-05-25
Release date:2007-10-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.12 Å)
Cite:Crystal structure, stability and in vitro RNAi activity of oligoribonucleotides containing the ribo-difluorotoluyl nucleotide: insights into substrate requirements by the human RISC Ago2 enzyme.
Nucleic Acids Res., 35, 2007
3D0G
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CRYSTAL STRUCTURE OF SPIKE PROTEIN RECEPTOR-BINDING DOMAIN FROM THE 2002-2003 SARS CORONAVIRUS HUMAN STRAIN COMPLEXED WITH HUMAN-CIVET CHIMERIC RECEPTOR ACE2
Descriptor:Angiotensin-converting enzyme 2, Spike glycoprotein, 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE, ...
Authors:Li, F.
Deposit date:2008-05-01
Release date:2008-07-08
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural analysis of major species barriers between humans and palm civets for severe acute respiratory syndrome coronavirus infections
J.Virol., 82, 2008
3D0H
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CRYSTAL STRUCTURE OF SPIKE PROTEIN RECEPTOR-BINDING DOMAIN FROM THE 2002-2003 SARS CORONAVIRUS CIVET STRAIN COMPLEXED WITH HUMAN-CIVET CHIMERIC RECEPTOR ACE2
Descriptor:Angiotensin-converting enzyme 2, Spike glycoprotein, 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE, ...
Authors:Li, F.
Deposit date:2008-05-01
Release date:2008-07-08
Last modified:2017-06-14
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural analysis of major species barriers between humans and palm civets for severe acute respiratory syndrome coronavirus infections
J.Virol., 82, 2008
3D0I
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CRYSTAL STRUCTURE OF SPIKE PROTEIN RECEPTOR-BINDING DOMAIN FROM THE 2005-2006 SARS CORONAVIRUS CIVET STRAIN COMPLEXED WITH HUMAN-CIVET CHIMERIC RECEPTOR ACE2
Descriptor:Angiotensin-converting enzyme 2, Spike glycoprotein, 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE, ...
Authors:Li, F.
Deposit date:2008-05-01
Release date:2008-07-08
Last modified:2017-06-28
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural analysis of major species barriers between humans and palm civets for severe acute respiratory syndrome coronavirus infections
J.Virol., 82, 2008
4ROU
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AUTO-INHIBITION MECHANISM OF HUMAN MITOCHONDRIAL RNASE P PROTEIN COMPLEX
Descriptor:Mitochondrial ribonuclease P protein 3, ZINC ION, CHLORIDE ION
Authors:Li, F., Liu, X., Yang, X., Shen, Y.
Deposit date:2014-10-29
Release date:2015-11-04
Method:X-RAY DIFFRACTION (2.713 Å)
Cite:Auto-inhibition Mechanism of Human Mitochondrial RNase P Protein Complex
TO BE PUBLISHED
4UC1
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HIGH RESOLUTION CRYSTAL STRUCTURE OF TRANSLOCATOR PROTEIN 18KDA (TSPO) FROM RHODOBACTER SPHAEROIDES (A139T MUTANT) IN C2 SPACE GROUP
Descriptor:Translocator protein TspO, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, PROTOPORPHYRIN IX, ...
Authors:Li, F., Liu, J., Zheng, Y., Garavito, R.M., Ferguson-Miller, S.
Deposit date:2014-08-13
Release date:2015-02-04
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structures of translocator protein (TSPO) and mutant mimic of a human polymorphism.
Science, 347, 2015
4UC2
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CRYSTAL STRUCTURE OF TRANSLOCATOR PROTEIN 18KDA (TSPO) FROM RHODOBACTER SPHAEROIDES (A139T MUTANT) IN P212121 SPACE GROUP
Descriptor:TRANSLOCATOR PROTEIN TSPO, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, TETRAETHYLENE GLYCOL
Authors:Li, F., Liu, J., Zheng, Y., Garavito, R.M., Ferguson-Miller, S.
Deposit date:2014-08-13
Release date:2015-02-04
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structures of translocator protein (TSPO) and mutant mimic of a human polymorphism.
Science, 347, 2015
4UC3
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TRANSLOCATOR PROTEIN 18 KDA (TSPO) FROM RHODOBACTER SPHAEROIDES WILD TYPE
Descriptor:TRANSLOCATOR PROTEIN TSPO, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-2-(hexadecanoyloxy)-3-hydroxypropyl (9Z)-octadec-9-enoate
Authors:Li, F., Liu, J., Zheng, Y., Garavito, R.M., Ferguson-Miller, S.
Deposit date:2014-08-13
Release date:2015-02-04
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structures of translocator protein (TSPO) and mutant mimic of a human polymorphism.
Science, 347, 2015
4XYW
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GLYCOSYLTRANSFERASES WBNH
Descriptor:O-antigen biosynthesis glycosyltransferase WbnH, SULFATE ION
Authors:Li, F.
Deposit date:2015-02-03
Release date:2016-02-10
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Glycosyltransferases WbnH
To Be Published
4Y3I
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PAS-GAF FRAGMENT FROM DEINOCOCCUS RADIODURANS BPHP ASSEMBLED WITH BV - Y307S, LOW DOSE
Descriptor:Bacteriophytochrome, 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-1-ium-2-ylidene]methyl]-5-[(Z)-[(3E)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid
Authors:Li, F., Burgie, E.S., Yu, T., Heroux, A., Schatz, G.C., Vierstra, R.D., Orville, A.M.
Deposit date:2015-02-10
Release date:2015-05-20
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:X-ray radiation induces deprotonation of the bilin chromophore in crystalline D. radiodurans phytochrome.
J.Am.Chem.Soc., 137, 2015
4Y5F
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PAS-GAF FRAGMENT FROM DEINOCOCCUS RADIODURANS BPHP ASSEMBLED WITH BV - Y307S, HIGH DOSE
Descriptor:Bacteriophytochrome, 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-1-ium-2-ylidene]methyl]-5-[(Z)-[(3E)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid
Authors:Li, F., Burgie, E.S., Yu, T., Heroux, A., Schatz, G.C., Vierstra, R.D., Orville, A.M.
Deposit date:2015-02-11
Release date:2015-05-20
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:X-ray radiation induces deprotonation of the bilin chromophore in crystalline D. radiodurans phytochrome.
J.Am.Chem.Soc., 137, 2015
5DUO
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CRYSTAL STRUCTURE OF NATIVE TRANSLOCATOR PROTEIN 18KDA (TSPO) FROM RHODOBACTER SPHAEROIDES (A139T MUTANT) IN C2 SPACE GROUP
Descriptor:Tryptophan-rich sensory protein, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, FORMIC ACID, ...
Authors:Li, F., Liu, J., Zheng, Y., Garavito, R.M., Ferguson-Miller, S.
Deposit date:2015-09-20
Release date:2015-11-11
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Response to Comment on "Crystal structures of translocator protein (TSPO) and mutant mimic of a human polymorphism".
Science, 350, 2015
5EOA
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CRYSTAL STRUCTURE OF OPTN E50K MUTANT AND TBK1 COMPLEX
Descriptor:Optineurin, Serine/threonine-protein kinase TBK1
Authors:Li, F., Xie, X., Liu, J., Pan, L.
Deposit date:2015-11-10
Release date:2016-09-28
Method:X-RAY DIFFRACTION (2.503 Å)
Cite:Structural insights into the interaction and disease mechanism of neurodegenerative disease-associated optineurin and TBK1 proteins.
Nat Commun, 7, 2016
5EOF
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CRYSTAL STRUCTURE OF OPTN NTD AND TBK1 CTD COMPLEX
Descriptor:Optineurin, Serine/threonine-protein kinase TBK1
Authors:Li, F., Xie, X., Liu, J., Pan, L.
Deposit date:2015-11-10
Release date:2016-09-28
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural insights into the interaction and disease mechanism of neurodegenerative disease-associated optineurin and TBK1 proteins.
Nat Commun, 7, 2016
5EP6
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THE CRYSTAL STRUCTURE OF NAP1 IN COMPLEX WITH TBK1
Descriptor:5-azacytidine-induced protein 2, Serine/threonine-protein kinase TBK1, GLYCEROL
Authors:Li, F., Xie, X., Liu, J., Pan, L.
Deposit date:2015-11-11
Release date:2016-09-28
Method:X-RAY DIFFRACTION (1.451 Å)
Cite:Structural insights into the interaction and disease mechanism of neurodegenerative disease-associated optineurin and TBK1 proteins.
Nat Commun, 7, 2016
5WQ4
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CRYSTAL STRUCTURE OF OPTN AND LINEAR DIUBIQUITIN COMPLEX
Descriptor:ubiquitin, Optineurin
Authors:Li, F., Pan, L.
Deposit date:2016-11-23
Release date:2017-12-06
Last modified:2018-12-19
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural insights into the ubiquitin recognition by OPTN (optineurin) and its regulation by TBK1-mediated phosphorylation.
Autophagy, 14, 2018
6MDW
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MECHANISM OF PROTEASE DEPENDENT DPC REPAIR
Descriptor:SprT-like domain-containing protein Spartan, CITRATE ANION, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Li, F., Raczynska, J., Chen, Z., Yu, H.
Deposit date:2018-09-05
Release date:2019-04-10
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural Insight into DNA-Dependent Activation of Human Metalloprotease Spartan.
Cell Rep, 26, 2019
6MDX
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MECHANISM OF PROTEASE DEPENDENT DPC REPAIR
Descriptor:SprT-like domain-containing protein Spartan, DNA (5'-D(P*CP*C)-3'), 1,2-ETHANEDIOL, ...
Authors:Li, F., Raczynska, J., Chen, Z., Yu, H.
Deposit date:2018-09-05
Release date:2019-04-10
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structural Insight into DNA-Dependent Activation of Human Metalloprotease Spartan.
Cell Rep, 26, 2019
4HJR
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CRYSTAL STRUCTURE OF F2YRS
Descriptor:Tyrosine-tRNA ligase
Authors:Wang, J., Tian, C., Gong, W., Li, F., Shi, P., Li, J., Ding, W.
Deposit date:2012-10-13
Release date:2013-03-13
Last modified:2013-05-22
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A genetically encoded 19F NMR probe for tyrosine phosphorylation.
Angew.Chem.Int.Ed.Engl., 52, 2013