Author results

3MFE
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CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS PROTEASOME OPEN-GATE MUTANT WITH H0 MOVEMENT
Descriptor:Proteasome subunit beta, Proteasome subunit alpha
Authors:Li, D., Li, H.
Deposit date:2010-04-02
Release date:2010-06-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis for the assembly and gate closure mechanisms of the Mycobacterium tuberculosis 20S proteasome.
Embo J., 2010
3MI0
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CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS PROTEASOME AT 2.2 A
Descriptor:Proteasome subunit alpha, Proteasome subunit beta, DIMETHYLFORMAMIDE, ...
Authors:Li, D., Li, H.
Deposit date:2010-04-09
Release date:2010-06-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis for the assembly and gate closure mechanisms of the Mycobacterium tuberculosis 20S proteasome.
Embo J., 2010
3MKA
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CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS PROTEASOME WITH PROPETIDE AND AN T1A MUTATION AT BETA-SUBUNIT
Descriptor:Proteasome subunit alpha, Proteasome subunit beta
Authors:Li, D., Li, H.
Deposit date:2010-04-14
Release date:2010-05-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Structural basis for the assembly and gate closure mechanisms of the Mycobacterium tuberculosis 20S proteasome.
Embo J., 29, 2010
1N25
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CRYSTAL STRUCTURE OF THE SV40 LARGE T ANTIGEN HELICASE DOMAIN
Descriptor:Large T Antigen, ZINC ION
Authors:Li, D., Zhao, R., Lilyestrom, W., Gai, D., Zhang, R., DeCaprio, J.A., Fanning, E., Jochimiak, A., Szakonyi, G., Chen, X.S.
Deposit date:2002-10-21
Release date:2003-06-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of the replicative helicase of the oncoprotein SV40 large tumour antigen
Nature, 423, 2003
2D4G
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STRUCTURE OF YJCG PROTEIN, A PUTATIVE 2'-5' RNA LIGASE FROM BACILLUS SUBTILIS
Descriptor:hypothetical protein BSU11850
Authors:Li, D., Liang, Y.H., Su, X.D.
Deposit date:2005-10-19
Release date:2006-10-17
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of B. subtilis YjcG characterizing the YjcG-like group of 2H phosphoesterase superfamily.
Proteins, 72, 2008
3RNY
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CRYSTAL STRUCTURE OF HUMAN RSK1 C-TERMINAL KINASE DOMAIN
Descriptor:Ribosomal protein S6 kinase alpha-1, SODIUM ION
Authors:Li, D., Fu, T.-M., Nan, J., Su, X.-D.
Deposit date:2011-04-24
Release date:2012-04-25
Last modified:2012-08-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis for the autoinhibition of the C-terminal kinase domain of human RSK1.
Acta Crystallogr.,Sect.D, 68, 2012
3ZE3
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CRYSTAL STRUCTURE OF THE INTEGRAL MEMBRANE DIACYLGLYCEROL KINASE - DELTA7
Descriptor:DIACYLGLYCEROL KINASE, (2R)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, ...
Authors:Li, D., Pye, V.E., Lyons, J.A., Vogeley, L., Aragao, D., Caffrey, M.
Deposit date:2012-12-03
Release date:2013-05-22
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal Structure of the Integral Membrane Diacylglycerol Kinase.
Nature, 497, 2013
3ZE4
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CRYSTAL STRUCTURE OF THE INTEGRAL MEMBRANE DIACYLGLYCEROL KINASE - WILD-TYPE
Descriptor:DIACYLGLYCEROL KINASE
Authors:Li, D., Lyons, J.A., Pye, V.E., Vogeley, L., Aragao, D., Caffrey, M.
Deposit date:2012-12-03
Release date:2013-05-22
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (3.702 Å)
Cite:Crystal Structure of the Integral Membrane Diacylglycerol Kinase.
Nature, 497, 2013
3ZE5
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CRYSTAL STRUCTURE OF THE INTEGRAL MEMBRANE DIACYLGLYCEROL KINASE - DELTA4
Descriptor:DIACYLGLYCEROL KINASE
Authors:Li, D., Vogeley, L., Pye, V.E., Lyons, J.A., Aragao, D., Caffrey, M.
Deposit date:2012-12-03
Release date:2013-05-22
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (3.101 Å)
Cite:Crystal Structure of the Integral Membrane Diacylglycerol Kinase.
Nature, 497, 2013
4UXW
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STRUCTURE OF DELTA4-DGKA-APO IN 9.9 MAG
Descriptor:DIACYLGLYCEROL KINASE, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (4S)-2-METHYL-2,4-PENTANEDIOL, ...
Authors:Li, D., Pye, V.E., Aragao, D., Caffrey, M.
Deposit date:2014-08-27
Release date:2015-09-30
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Ternary Structure Reveals Mechanism of a Membrane Diacylglycerol Kinase.
Nat.Commun., 6, 2015
4CJZ
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CRYSTAL STRUCTURE OF THE INTEGRAL MEMBRANE DIACYLGLYCEROL KINASE DGKA- 9.9, DELTA 4
Descriptor:DIACYLGLYCEROL KINASE, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate
Authors:Li, D., Aragao, D., Pye, V.E., Caffrey, M.
Deposit date:2013-12-23
Release date:2015-01-28
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Crystal Structure of the Integral Membrane Diacylglycerol Kinase with Zn-Amppcp Bound and its Catalytic Mechanism
To be Published
4CK0
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CRYSTAL STRUCTURE OF THE INTEGRAL MEMBRANE DIACYLGLYCEROL KINASE - FORM 2
Descriptor:DIACYLGLYCEROL KINASE, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, ZINC ION, ...
Authors:Li, D., Lyons, J.A., Vogeley, L., Aragao, D., Caffrey, M.
Deposit date:2013-12-23
Release date:2015-01-28
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (2.924 Å)
Cite:Crystal Structure of the Integral Membrane Diacylglycerol Kinase with Zn-Amppcp Bound and its Catalytic Mechanism
To be Published
4UXX
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STRUCTURE OF DELTA4-DGKA WITH AMPPCP IN 9.9 MAG
Descriptor:DIACYLGLYCEROL KINASE, CHLORIDE ION, SODIUM ION, ...
Authors:Li, D., Vogeley, L., Caffrey, M.
Deposit date:2014-08-27
Release date:2015-09-30
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (2.701 Å)
Cite:Ternary Structure Reveals Mechanism of a Membrane Diacylglycerol Kinase.
Nat.Commun., 6, 2015
4UXZ
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STRUCTURE OF DELTA7-DGKA-SYN IN 7.9 MAG TO 2.18 ANGSTROM RESOLUTION
Descriptor:DIACYLGLYCEROL KINASE-DELTA 7, (2S)-2,3-dihydroxypropyl (7Z)-hexadec-7-enoate, (2R)-2,3-dihydroxypropyl (7Z)-hexadec-7-enoate, ...
Authors:Li, D., Howe, N., Caffrey, M.
Deposit date:2014-08-27
Release date:2015-09-30
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Ternary Structure Reveals Mechanism of a Membrane Diacylglycerol Kinase.
Nat.Commun., 6, 2015
4UYO
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STRUCTURE OF DELTA7-DGKA IN 7.9 MAG BY SERIAL FEMTOSECOND CRYSTATALLOGRAPHY TO 2.18 ANGSTROM RESOLUTION
Descriptor:DIACYLGLYCEROL KINASE-DELTA 7, (2S)-2,3-dihydroxypropyl (7Z)-hexadec-7-enoate, (2R)-2,3-dihydroxypropyl (7Z)-hexadec-7-enoate, ...
Authors:Li, D., Howe, N., Other, O., Caffrey, M.
Deposit date:2014-09-02
Release date:2015-09-30
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Ternary Structure Reveals Mechanism of a Membrane Diacylglycerol Kinase.
Nat.Commun., 6, 2015
1NIX
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THREE DIMENSIONAL SOLUTION STRUCTURE OF HAINANTOXIN-I BY 2D 1H-NMR
Descriptor:HAINANTOXIN-I
Authors:Li, D., Liang, S.
Deposit date:2002-12-29
Release date:2003-01-14
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Function and solution structure of hainantoxin-I, a novel insect sodium channel inhibitor from the Chinese bird spider Selenocosmia hainana.
Febs Lett., 555, 2003
1NIY
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THREE DIMENSIONAL SOLUTION STRUCTURE OF HAINANTOXIN-IV BY 2D 1H-NMR
Descriptor:HAINANTOXIN-IV
Authors:Li, D., Lu, S., Gu, X., Liang, S.
Deposit date:2002-12-30
Release date:2003-01-14
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Structure-Activity Relationships of Hainantoxin-IV and Structure Determination of Active and Inactive Sodium Channel Blockers.
J.Biol.Chem., 279, 2004
1RYG
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THREE DIMENSIONAL SOLUTION STRUCTURE OF THE R29A MUTANT OF SODIUM CHANNELS INHIBITOR HAINANTOXIN-IV BY 2D 1H-NMR
Descriptor:Hainantoxin-IV
Authors:Li, D., Lu, S., Gu, X., Liang, S.
Deposit date:2003-12-22
Release date:2004-01-13
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure--activity relationships of hainantoxin-IV and structure determination of active and inactive sodium channel blockers
J.Biol.Chem., 279, 2004
1RYV
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THREE DIMENSIONAL SOLUTION STRUCTURE OF THE K27A MUTANT OF SODIUM CHANNELS INHIBITOR HAINANTOXIN-IV BY 2D 1H-NMR
Descriptor:Hainantoxin-IV
Authors:Li, D., Lu, S., Gu, X., Liang, S.
Deposit date:2003-12-22
Release date:2004-01-13
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure--activity relationships of hainantoxin-IV and structure determination of active and inactive sodium channel blockers
J.Biol.Chem., 279, 2004
4BPM
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CRYSTAL STRUCTURE OF A HUMAN INTEGRAL MEMBRANE ENZYME
Descriptor:PROSTAGLANDIN E SYNTHASE, FUSION PEPTIDE, GLUTATHIONE, ...
Authors:Li, D., Wang, M., Olieric, V., Caffrey, M.
Deposit date:2013-05-27
Release date:2014-04-16
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Crystallizing Membrane Proteins in the Lipidic Mesophase. Experience with Human Prostaglandin E2 Synthase 1 and an Evolving Strategy.
Cryst.Growth Des., 14, 2014
4BRB
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CRYSTAL STRUCTURE OF THE INTEGRAL MEMBRANE ENZYME DGKA-REF, DELTA 7
Descriptor:DIACYLGLYCEROL KINASE, (2R)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, ZINC ION, ...
Authors:Li, D., Caffrey, M.
Deposit date:2013-06-04
Release date:2014-06-18
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Renaturing Membrane Proteins in the Lipid Cubic Phase, a Nanoporous Membrane Mimetic.
Sci.Rep., 4, 2014
4BRR
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CRYSTAL STRUCTURE OF THE INTEGRAL MEMBRANE DIACYLGLYCEROL KINASE - DELTA 7.79
Descriptor:DIACYLGLYCEROL KINASE, (2R)-2,3-dihydroxypropyl (7Z)-hexadec-7-enoate, ZINC ION, ...
Authors:Li, D., Howe, N., Caffrey, M.
Deposit date:2013-06-05
Release date:2014-06-18
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (2.44 Å)
Cite:Crystal Structure of an Integral Membrane Enzyme Determined by X-Ray Free Electron Laser Femtocrystallography
To be Published
4UP6
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CRYSTAL STRUCTURE OF THE WILD-TYPE DIACYLGLYCEROL KINASE REFOLDED IN THE LIPID CUBIC PHASE
Descriptor:DIACYLGLYCEROL KINASE
Authors:Li, D., Caffrey, M.
Deposit date:2014-06-13
Release date:2014-10-22
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (3.801 Å)
Cite:Renaturing Membrane Proteins in the Lipid Cubic Phase, a Nanoporous Membrane Mimetic.
Sci.Rep., 4, 2014
2RI0
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CRYSTAL STRUCTURE OF GLUCOSAMINE 6-PHOSPHATE DEAMINASE (NAGB) FROM S. MUTANS
Descriptor:Glucosamine-6-phosphate deaminase, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, SODIUM ION
Authors:Li, D., Liu, C., Li, L.F., Su, X.D.
Deposit date:2007-10-10
Release date:2008-03-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Ring-opening mechanism revealed by crystal structures of NagB and its ES intermediate complex
J.Mol.Biol., 379, 2008
3H6F
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CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS PROTEASOME MODIFIED BY INHIBITOR HT1171
Descriptor:Proteasome (Alpha subunit) PrcA, Proteasome (Beta subunit) PrcB, DIMETHYLFORMAMIDE
Authors:Li, D., Li, H., Lin, G.
Deposit date:2009-04-23
Release date:2009-09-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Inhibitors selective for mycobacterial versus human proteasomes.
Nature, 461, 2009