Author results

3TLQ
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CRYSTAL STRUCTURE OF EAL-LIKE DOMAIN PROTEIN YDIV
Descriptor:Regulatory protein YdiV, PHOSPHATE ION, GLYCEROL
Authors:Li, B., Li, N., Wang, F., Guo, L., Liu, C., Zhu, D., Xu, S., Gu, L.
Deposit date:2011-08-30
Release date:2012-09-12
Last modified:2013-07-03
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Structural insight of a concentration-dependent mechanism by which YdiV inhibits Escherichia coli flagellum biogenesis and motility
Nucleic Acids Res., 40, 2012
5HXF
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CRYSTAL STRUCTURE OF 3C PROTEASE FROM A MILD HUMAN ENTEROVIRUS 71 IN COMPLEX WITH RUPINTRIVIR
Descriptor:3C protease, 4-{2-(4-FLUORO-BENZYL)-6-METHYL-5-[(5-METHYL-ISOXAZOLE-3-CARBONYL)-AMINO]-4-OXO-HEPTANOYLAMINO}-5-(2-OXO-PYRROLIDIN-3-YL)-PENTANOIC ACID ETHYL ESTER, SULFATE ION
Authors:Li, B., Yuan, Z., Qin, L., Gu, L.
Deposit date:2016-01-30
Release date:2017-02-15
Method:X-RAY DIFFRACTION (1.39 Å)
Cite:Crystal structure of 3C protease from a mild Human enterovirus 71 in complex with rupintrivir
To Be Published
5HXG
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STM1697-FLHD COMPLEX
Descriptor:Uncharacterized protein STM1697, Flagellar transcriptional regulator FlhD
Authors:Li, B., Yuan, Z., Qin, L., Gu, L.
Deposit date:2016-01-30
Release date:2017-02-15
Method:X-RAY DIFFRACTION (1.998 Å)
Cite:Crystal structure of STM1697-FlhD complex
To Be Published
5VVO
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STRUCTURAL INVESTIGATIONS OF THE SUBSTRATE SPECIFICITY OF HUMAN O-GLCNACASE
Descriptor:Protein O-GlcNAcase
Authors:Li, B., Jiang, J., Li, H., Hu, C.-W.
Deposit date:2017-05-19
Release date:2017-09-27
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural insights into the substrate binding adaptability and specificity of human O-GlcNAcase.
Nat Commun, 8, 2017
5VVT
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STRUCTURAL INVESTIGATIONS OF THE SUBSTRATE SPECIFICITY OF HUMAN O-GLCNACASE
Descriptor:Protein O-GlcNAcase, ELK1 peptide, N-ACETYL-D-GLUCOSAMINE
Authors:Li, B., Jiang, J., Li, H., Hu, C.-W.
Deposit date:2017-05-20
Release date:2017-09-27
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural insights into the substrate binding adaptability and specificity of human O-GlcNAcase.
Nat Commun, 8, 2017
5VVU
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STRUCTURAL INVESTIGATIONS OF THE SUBSTRATE SPECIFICITY OF HUMAN O-GLCNACASE
Descriptor:Protein O-GlcNAcase, TAB1 peptide, N-ACETYL-D-GLUCOSAMINE
Authors:Li, B., Jiang, J., Li, H., Hu, C.-W.
Deposit date:2017-05-20
Release date:2017-09-27
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural insights into the substrate binding adaptability and specificity of human O-GlcNAcase.
Nat Commun, 8, 2017
5VVV
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STRUCTURAL INVESTIGATIONS OF THE SUBSTRATE SPECIFICITY OF HUMAN O-GLCNACASE
Descriptor:Protein O-GlcNAcase, a-crystallin B, N-ACETYL-D-GLUCOSAMINE
Authors:Li, B., Jiang, J., Li, H., Hu, C.-W.
Deposit date:2017-05-20
Release date:2017-09-27
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural insights into the substrate binding adaptability and specificity of human O-GlcNAcase.
Nat Commun, 8, 2017
5VVX
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STRUCTURAL INVESTIGATIONS OF THE SUBSTRATE SPECIFICITY OF HUMAN O-GLCNACASE
Descriptor:Protein O-GlcNAcase, Lamin B1, N-ACETYL-D-GLUCOSAMINE
Authors:Li, B., Jiang, J., Li, H., Hu, C.-W.
Deposit date:2017-05-21
Release date:2017-09-27
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural insights into the substrate binding adaptability and specificity of human O-GlcNAcase.
Nat Commun, 8, 2017
4ES4
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CRYSTAL STRUCTURE OF YDIV AND FLHD COMPLEX
Descriptor:Putative cyclic di-GMP regulator CdgR, Flagellar transcriptional regulator FlhD
Authors:Li, B., Gu, L.
Deposit date:2012-04-22
Release date:2012-10-10
Last modified:2013-07-03
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural insight of a concentration-dependent mechanism by which YdiV inhibits Escherichia coli flagellum biogenesis and motility
Nucleic Acids Res., 40, 2012
5TKE
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CRYSTAL STRUCTURE OF EUKARYOTIC HYDROLASE
Descriptor:O-GlcNAcase: chimera construct
Authors:Li, B., Jiang, J.
Deposit date:2016-10-06
Release date:2017-03-15
Last modified:2017-04-19
Method:X-RAY DIFFRACTION (2.481 Å)
Cite:Structures of human O-GlcNAcase and its complexes reveal a new substrate recognition mode.
Nat. Struct. Mol. Biol., 24, 2017
5UN8
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CRYSTAL STRUCTURE OF HUMAN O-GLCNACASE IN COMPLEX WITH GLYCOPEPTIDE P53
Descriptor:Protein O-GlcNAcase, P53 peptide, N-ACETYL-D-GLUCOSAMINE
Authors:Li, B., Jiang, J.
Deposit date:2017-01-30
Release date:2017-03-15
Last modified:2017-04-19
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Structures of human O-GlcNAcase and its complexes reveal a new substrate recognition mode.
Nat. Struct. Mol. Biol., 24, 2017
5UN9
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THE CRYSTAL STRUCTURE OF HUMAN O-GLCNACASE IN COMPLEX WITH THIAMET-G
Descriptor:Protein O-GlcNAcase, (3AR,5R,6S,7R,7AR)-2-(ETHYLAMINO)-5-(HYDROXYMETHYL)-5,6,7,7A-TETRAHYDRO-3AH-PYRANO[3,2-D][1,3]THIAZOLE-6,7-DIOL
Authors:Li, B., Jiang, J.
Deposit date:2017-01-30
Release date:2017-03-15
Last modified:2017-04-19
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structures of human O-GlcNAcase and its complexes reveal a new substrate recognition mode.
Nat. Struct. Mol. Biol., 24, 2017
4F7W
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CRYSTAL STRUCTURE OF KLEBSIELLA PNEUMONIAE PANTOTHENATE KINASE IN COMPLEX WITH N-PENTYLPANTOTHENAMIDE
Descriptor:Pantothenate kinase, ADENOSINE-5'-DIPHOSPHATE, (2R)-2,4-dihydroxy-3,3-dimethyl-N-[3-oxo-3-(pentylamino)propyl]butanamide, ...
Authors:Li, B., Tempel, W., Smil, D., Bolshan, Y., Hong, B.S., Park, H.W., Structural Genomics Consortium (SGC)
Deposit date:2012-05-16
Release date:2013-04-10
Last modified:2013-08-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structures of Klebsiella pneumoniae pantothenate kinase in complex with N-substituted pantothenamides.
Proteins, 81, 2013
4GI7
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CRYSTAL STRUCTURE OF KLEBSIELLA PNEUMONIAE PANTOTHENATE KINASE IN COMPLEX WITH A PANTOTHENATE ANALOGUE
Descriptor:Pantothenate kinase, ADENOSINE-5'-DIPHOSPHATE, (2R)-2,4-dihydroxy-3,3-dimethyl-N-{3-oxo-3-[(pyridin-3-ylmethyl)amino]propyl}butanamide, ...
Authors:Li, B., Tempel, W., Smil, D., Bolshan, Y., Hong, B.S., Park, H.W., Structural Genomics Consortium (SGC)
Deposit date:2012-08-08
Release date:2013-04-10
Last modified:2013-08-07
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structures of Klebsiella pneumoniae pantothenate kinase in complex with N-substituted pantothenamides.
Proteins, 81, 2013
5WQ2
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CRYSTAL STRUCTURE OF 3C PROTEASE FROM A MILD HUMAN ENTEROVIRUS 71 IN COMPLEX WITH RUPINTRIVIR
Descriptor:3C protein, 4-{2-(4-FLUORO-BENZYL)-6-METHYL-5-[(5-METHYL-ISOXAZOLE-3-CARBONYL)-AMINO]-4-OXO-HEPTANOYLAMINO}-5-(2-OXO-PYRROLIDIN-3-YL)-PENTANOIC ACID ETHYL ESTER, SULFATE ION
Authors:Li, B., Yuan, Z.
Deposit date:2016-11-22
Release date:2017-11-29
Method:X-RAY DIFFRACTION (1.39 Å)
Cite:Crystal structure of 3C protease from a mild Human enterovirus 71 in complex with rupintrivir
To Be Published
6CU7
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ALPHA SYNUCLEIN FIBRIL FORMED BY FULL LENGTH PROTEIN - ROD POLYMORPH
Descriptor:Alpha-synuclein
Authors:Li, B., Hatami, A., Ge, P., Murray, K.A., Sheth, P., Zhang, M., Nair, G., Sawaya, M.R., Zhu, C., Broad, M., Shin, W.S., Ye, S., John, V., Eisenberg, D.S., Zhou, Z.H., Jiang, L.
Deposit date:2018-03-23
Release date:2018-09-12
Last modified:2019-02-27
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Cryo-EM of full-length alpha-synuclein reveals fibril polymorphs with a common structural kernel.
Nat Commun, 9, 2018
6CU8
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ALPHA SYNUCLEIN FIBRIL FORMED BY FULL LENGTH PROTEIN - TWISTER POLYMORPH
Descriptor:Alpha-synuclein
Authors:Li, B., Hatami, A., Ge, P., Murray, K.A., Sheth, P., Zhang, M., Nair, G., Sawaya, M.R., Zhu, C., Broad, M., Shin, W.S., Ye, S., John, V., Eisenberg, D.S., Zhou, Z.H., Jiang, L.
Deposit date:2018-03-23
Release date:2018-09-12
Last modified:2019-02-27
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM of full-length alpha-synuclein reveals fibril polymorphs with a common structural kernel.
Nat Commun, 9, 2018
4L7F
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CO-CRYSTAL STRUCTURE OF JNK1 AND AX13587
Descriptor:Mitogen-activated protein kinase 8, N-[1-(4-fluorophenyl)cyclopropyl]-4-[(trans-4-hydroxycyclohexyl)amino]imidazo[1,2-a]quinoxaline-8-carboxamide
Authors:Walter, R.L., Ranieri, G.M., Riggs, A.M., Weissig, H., Li, B., Shreder, K.R.
Deposit date:2013-06-13
Release date:2013-08-21
Last modified:2013-10-09
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Hit-to-lead optimization and kinase selectivity of imidazo[1,2-a]quinoxalin-4-amine derived JNK1 inhibitors.
Bioorg.Med.Chem.Lett., 23, 2013
5HKP
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CRYSTAL STRUCTURE OF MOUSE TANKYRASE/HUMAN TRF1 COMPLEX
Descriptor:Tankyrase-1, Telomeric repeat-binding factor 1
Authors:Wang, Z., Li, B., Rao, Z., Xu, W.
Deposit date:2016-01-14
Release date:2016-03-23
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of a tankyrase 1-telomere repeat factor 1 complex.
Acta Crystallogr F Struct Biol Commun, 72, 2016
3PFT
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CRYSTAL STRUCTURE OF UNTAGGED C54A MUTANT FLAVIN REDUCTASE (DSZD) IN COMPLEX WITH FMN FROM MYCOBACTERIUM GOODII
Descriptor:Flavin reductase, FLAVIN MONONUCLEOTIDE
Authors:Li, Q., Xu, P., Ma, C., Gu, L., Liu, X., Zhang, C., Li, N., Su, J., Li, B., Liu, S.
Deposit date:2010-10-29
Release date:2011-11-02
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.601 Å)
Cite:The flavin reductase DSZD from a desulfurizing mycobacterium goodii strain: systemic manipulation and investigation based on the crystal structure
To be Published
5VIE
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ELECTROPHILIC PROBES FOR DECIPHERING SUBSTRATE RECOGNITION BY O-GLCNAC TRANSFERASE
Descriptor:UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit, CKII, URIDINE-5'-DIPHOSPHATE, ...
Authors:Jiang, J., Li, B., Hu, C.-W., Worth, M., Fan, D., Li, H.
Deposit date:2017-04-15
Release date:2017-10-18
Last modified:2017-12-06
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Electrophilic probes for deciphering substrate recognition by O-GlcNAc transferase.
Nat. Chem. Biol., 13, 2017
5VIF
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ELECTROPHILIC PROBES FOR DECIPHERING SUBSTRATE RECOGNITION BY O-GLCNAC TRANSFERASE
Descriptor:UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit, CKII, URIDINE-5'-DIPHOSPHATE, ...
Authors:Jiang, J., Li, B., Hu, C.-W., Worth, M., Fan, D., Li, H.
Deposit date:2017-04-15
Release date:2017-10-18
Last modified:2017-12-06
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Electrophilic probes for deciphering substrate recognition by O-GlcNAc transferase.
Nat. Chem. Biol., 13, 2017
3DL4
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NON-AGED FORM OF MOUSE ACETYLCHOLINESTERASE INHIBITED BY TABUN- UPDATE
Descriptor:Acetylcholinesterase, HEXAETHYLENE GLYCOL
Authors:Carletti, E., Li, H., Li, B., Ekstrom, F., Nicolet, Y., Loiodice, M., Gillon, E., Froment, M.T., Lockridge, O., Schopfer, L.M., Masson, P., Nachon, F.
Deposit date:2008-06-26
Release date:2008-12-02
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Aging of Cholinesterases Phosphylated by Tabun Proceeds through O-Dealkylation.
J.Am.Chem.Soc., 130, 2008
3DL7
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AGED FORM OF MOUSE ACETYLCHOLINESTERASE INHIBITED BY TABUN- UPDATE
Descriptor:Acetylcholinesterase, N-ACETYL-D-GLUCOSAMINE, CHLORIDE ION, ...
Authors:Carletti, E., Li, H., Li, B., Ekstrom, F., Nicolet, Y., Loiodice, M., Gillon, E., Froment, M.T., Lockridge, O., Schopfer, L.M., Masson, P., Nachon, F.
Deposit date:2008-06-26
Release date:2008-12-02
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Aging of Cholinesterases Phosphylated by Tabun Proceeds through O-Dealkylation.
J.Am.Chem.Soc., 130, 2008
3R5S
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CRYSTAL STRUCTURE OF APO-VIUP
Descriptor:Ferric vibriobactin ABC transporter, periplasmic ferric vibriobactin-binding protein
Authors:Li, N., Zhang, C., Li, B., Liu, X., Huang, Y., Xu, S., Gu, L.
Deposit date:2011-03-19
Release date:2012-02-08
Last modified:2012-05-30
Method:X-RAY DIFFRACTION (1.791 Å)
Cite:Unique iron coordination in iron-chelating molecule vibriobactin helps Vibrio cholerae evade mammalian siderocalin-mediated immune response.
J.Biol.Chem., 287, 2012