Author results

3TLQ
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CRYSTAL STRUCTURE OF EAL-LIKE DOMAIN PROTEIN YDIV
分子名称:Regulatory protein YdiV, PHOSPHATE ION, GLYCEROL
著者Li, B., Li, N., Wang, F., Guo, L., Liu, C., Zhu, D., Xu, S., Gu, L.
登録日2011-08-30
公開日2012-09-12
最終更新日2013-07-03
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Structural insight of a concentration-dependent mechanism by which YdiV inhibits Escherichia coli flagellum biogenesis and motility
Nucleic Acids Res., 40, 2012
5HXF
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CRYSTAL STRUCTURE OF 3C PROTEASE FROM A MILD HUMAN ENTEROVIRUS 71 IN COMPLEX WITH RUPINTRIVIR
分子名称:3C protease, 4-{2-(4-FLUORO-BENZYL)-6-METHYL-5-[(5-METHYL-ISOXAZOLE-3-CARBONYL)-AMINO]-4-OXO-HEPTANOYLAMINO}-5-(2-OXO-PYRROLIDIN-3-YL)-PENTANOIC ACID ETHYL ESTER, SULFATE ION
著者Li, B., Yuan, Z., Qin, L., Gu, L.
登録日2016-01-30
公開日2017-02-15
実験手法X-RAY DIFFRACTION (1.39 Å)
主引用文献Crystal structure of 3C protease from a mild Human enterovirus 71 in complex with rupintrivir
To Be Published
5HXG
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STM1697-FLHD COMPLEX
分子名称:Uncharacterized protein STM1697, Flagellar transcriptional regulator FlhD
著者Li, B., Yuan, Z., Qin, L., Gu, L.
登録日2016-01-30
公開日2017-02-15
実験手法X-RAY DIFFRACTION (1.998 Å)
主引用文献Crystal structure of STM1697-FlhD complex
To Be Published
5VVO
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STRUCTURAL INVESTIGATIONS OF THE SUBSTRATE SPECIFICITY OF HUMAN O-GLCNACASE
分子名称:Protein O-GlcNAcase
著者Li, B., Jiang, J., Li, H., Hu, C.-W.
登録日2017-05-19
公開日2017-09-27
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural insights into the substrate binding adaptability and specificity of human O-GlcNAcase.
Nat Commun, 8, 2017
5VVT
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STRUCTURAL INVESTIGATIONS OF THE SUBSTRATE SPECIFICITY OF HUMAN O-GLCNACASE
分子名称:Protein O-GlcNAcase, ELK1 peptide, N-ACETYL-D-GLUCOSAMINE
著者Li, B., Jiang, J., Li, H., Hu, C.-W.
登録日2017-05-20
公開日2017-09-27
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural insights into the substrate binding adaptability and specificity of human O-GlcNAcase.
Nat Commun, 8, 2017
5VVU
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STRUCTURAL INVESTIGATIONS OF THE SUBSTRATE SPECIFICITY OF HUMAN O-GLCNACASE
分子名称:Protein O-GlcNAcase, TAB1 peptide, N-ACETYL-D-GLUCOSAMINE
著者Li, B., Jiang, J., Li, H., Hu, C.-W.
登録日2017-05-20
公開日2017-09-27
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural insights into the substrate binding adaptability and specificity of human O-GlcNAcase.
Nat Commun, 8, 2017
5VVV
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STRUCTURAL INVESTIGATIONS OF THE SUBSTRATE SPECIFICITY OF HUMAN O-GLCNACASE
分子名称:Protein O-GlcNAcase, a-crystallin B, N-ACETYL-D-GLUCOSAMINE
著者Li, B., Jiang, J., Li, H., Hu, C.-W.
登録日2017-05-20
公開日2017-09-27
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural insights into the substrate binding adaptability and specificity of human O-GlcNAcase.
Nat Commun, 8, 2017
5VVX
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STRUCTURAL INVESTIGATIONS OF THE SUBSTRATE SPECIFICITY OF HUMAN O-GLCNACASE
分子名称:Protein O-GlcNAcase, Lamin B1, N-ACETYL-D-GLUCOSAMINE
著者Li, B., Jiang, J., Li, H., Hu, C.-W.
登録日2017-05-21
公開日2017-09-27
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural insights into the substrate binding adaptability and specificity of human O-GlcNAcase.
Nat Commun, 8, 2017
4ES4
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CRYSTAL STRUCTURE OF YDIV AND FLHD COMPLEX
分子名称:Putative cyclic di-GMP regulator CdgR, Flagellar transcriptional regulator FlhD
著者Li, B., Gu, L.
登録日2012-04-22
公開日2012-10-10
最終更新日2013-07-03
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural insight of a concentration-dependent mechanism by which YdiV inhibits Escherichia coli flagellum biogenesis and motility
Nucleic Acids Res., 40, 2012
5TKE
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CRYSTAL STRUCTURE OF EUKARYOTIC HYDROLASE
分子名称:O-GlcNAcase: chimera construct
著者Li, B., Jiang, J.
登録日2016-10-06
公開日2017-03-15
最終更新日2017-04-19
実験手法X-RAY DIFFRACTION (2.481 Å)
主引用文献Structures of human O-GlcNAcase and its complexes reveal a new substrate recognition mode.
Nat. Struct. Mol. Biol., 24, 2017
5UN8
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CRYSTAL STRUCTURE OF HUMAN O-GLCNACASE IN COMPLEX WITH GLYCOPEPTIDE P53
分子名称:Protein O-GlcNAcase, P53 peptide, N-ACETYL-D-GLUCOSAMINE
著者Li, B., Jiang, J.
登録日2017-01-30
公開日2017-03-15
最終更新日2017-04-19
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献Structures of human O-GlcNAcase and its complexes reveal a new substrate recognition mode.
Nat. Struct. Mol. Biol., 24, 2017
5UN9
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THE CRYSTAL STRUCTURE OF HUMAN O-GLCNACASE IN COMPLEX WITH THIAMET-G
分子名称:Protein O-GlcNAcase, (3AR,5R,6S,7R,7AR)-2-(ETHYLAMINO)-5-(HYDROXYMETHYL)-5,6,7,7A-TETRAHYDRO-3AH-PYRANO[3,2-D][1,3]THIAZOLE-6,7-DIOL
著者Li, B., Jiang, J.
登録日2017-01-30
公開日2017-03-15
最終更新日2017-04-19
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structures of human O-GlcNAcase and its complexes reveal a new substrate recognition mode.
Nat. Struct. Mol. Biol., 24, 2017
4F7W
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CRYSTAL STRUCTURE OF KLEBSIELLA PNEUMONIAE PANTOTHENATE KINASE IN COMPLEX WITH N-PENTYLPANTOTHENAMIDE
分子名称:Pantothenate kinase, ADENOSINE-5'-DIPHOSPHATE, (2R)-2,4-dihydroxy-3,3-dimethyl-N-[3-oxo-3-(pentylamino)propyl]butanamide, ...
著者Li, B., Tempel, W., Smil, D., Bolshan, Y., Hong, B.S., Park, H.W., Structural Genomics Consortium (SGC)
登録日2012-05-16
公開日2013-04-10
最終更新日2013-08-07
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structures of Klebsiella pneumoniae pantothenate kinase in complex with N-substituted pantothenamides.
Proteins, 81, 2013
4GI7
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CRYSTAL STRUCTURE OF KLEBSIELLA PNEUMONIAE PANTOTHENATE KINASE IN COMPLEX WITH A PANTOTHENATE ANALOGUE
分子名称:Pantothenate kinase, ADENOSINE-5'-DIPHOSPHATE, (2R)-2,4-dihydroxy-3,3-dimethyl-N-{3-oxo-3-[(pyridin-3-ylmethyl)amino]propyl}butanamide, ...
著者Li, B., Tempel, W., Smil, D., Bolshan, Y., Hong, B.S., Park, H.W., Structural Genomics Consortium (SGC)
登録日2012-08-08
公開日2013-04-10
最終更新日2013-08-07
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal structures of Klebsiella pneumoniae pantothenate kinase in complex with N-substituted pantothenamides.
Proteins, 81, 2013
5WQ2
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CRYSTAL STRUCTURE OF 3C PROTEASE FROM A MILD HUMAN ENTEROVIRUS 71 IN COMPLEX WITH RUPINTRIVIR
分子名称:3C protein, 4-{2-(4-FLUORO-BENZYL)-6-METHYL-5-[(5-METHYL-ISOXAZOLE-3-CARBONYL)-AMINO]-4-OXO-HEPTANOYLAMINO}-5-(2-OXO-PYRROLIDIN-3-YL)-PENTANOIC ACID ETHYL ESTER, SULFATE ION
著者Li, B., Yuan, Z.
登録日2016-11-22
公開日2017-11-29
実験手法X-RAY DIFFRACTION (1.39 Å)
主引用文献Crystal structure of 3C protease from a mild Human enterovirus 71 in complex with rupintrivir
To Be Published
6CU7
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ALPHA SYNUCLEIN FIBRIL FORMED BY FULL LENGTH PROTEIN - ROD POLYMORPH
分子名称:Alpha-synuclein
著者Li, B., Hatami, A., Ge, P., Murray, K.A., Sheth, P., Zhang, M., Nair, G., Sawaya, M.R., Zhu, C., Broad, M., Shin, W.S., Ye, S., John, V., Eisenberg, D.S., Zhou, Z.H., Jiang, L.
登録日2018-03-23
公開日2018-09-12
最終更新日2019-02-27
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Cryo-EM of full-length alpha-synuclein reveals fibril polymorphs with a common structural kernel.
Nat Commun, 9, 2018
6CU8
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ALPHA SYNUCLEIN FIBRIL FORMED BY FULL LENGTH PROTEIN - TWISTER POLYMORPH
分子名称:Alpha-synuclein
著者Li, B., Hatami, A., Ge, P., Murray, K.A., Sheth, P., Zhang, M., Nair, G., Sawaya, M.R., Zhu, C., Broad, M., Shin, W.S., Ye, S., John, V., Eisenberg, D.S., Zhou, Z.H., Jiang, L.
登録日2018-03-23
公開日2018-09-12
最終更新日2019-02-27
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Cryo-EM of full-length alpha-synuclein reveals fibril polymorphs with a common structural kernel.
Nat Commun, 9, 2018
4L7F
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CO-CRYSTAL STRUCTURE OF JNK1 AND AX13587
分子名称:Mitogen-activated protein kinase 8, N-[1-(4-fluorophenyl)cyclopropyl]-4-[(trans-4-hydroxycyclohexyl)amino]imidazo[1,2-a]quinoxaline-8-carboxamide
著者Walter, R.L., Ranieri, G.M., Riggs, A.M., Weissig, H., Li, B., Shreder, K.R.
登録日2013-06-13
公開日2013-08-21
最終更新日2013-10-09
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Hit-to-lead optimization and kinase selectivity of imidazo[1,2-a]quinoxalin-4-amine derived JNK1 inhibitors.
Bioorg.Med.Chem.Lett., 23, 2013
5HKP
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CRYSTAL STRUCTURE OF MOUSE TANKYRASE/HUMAN TRF1 COMPLEX
分子名称:Tankyrase-1, Telomeric repeat-binding factor 1
著者Wang, Z., Li, B., Rao, Z., Xu, W.
登録日2016-01-14
公開日2016-03-23
最終更新日2018-04-18
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of a tankyrase 1-telomere repeat factor 1 complex.
Acta Crystallogr F Struct Biol Commun, 72, 2016
3PFT
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CRYSTAL STRUCTURE OF UNTAGGED C54A MUTANT FLAVIN REDUCTASE (DSZD) IN COMPLEX WITH FMN FROM MYCOBACTERIUM GOODII
分子名称:Flavin reductase, FLAVIN MONONUCLEOTIDE
著者Li, Q., Xu, P., Ma, C., Gu, L., Liu, X., Zhang, C., Li, N., Su, J., Li, B., Liu, S.
登録日2010-10-29
公開日2011-11-02
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (1.601 Å)
主引用文献The flavin reductase DSZD from a desulfurizing mycobacterium goodii strain: systemic manipulation and investigation based on the crystal structure
To be Published
5VIE
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ELECTROPHILIC PROBES FOR DECIPHERING SUBSTRATE RECOGNITION BY O-GLCNAC TRANSFERASE
分子名称:UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit, CKII, URIDINE-5'-DIPHOSPHATE, ...
著者Jiang, J., Li, B., Hu, C.-W., Worth, M., Fan, D., Li, H.
登録日2017-04-15
公開日2017-10-18
最終更新日2017-12-06
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Electrophilic probes for deciphering substrate recognition by O-GlcNAc transferase.
Nat. Chem. Biol., 13, 2017
5VIF
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ELECTROPHILIC PROBES FOR DECIPHERING SUBSTRATE RECOGNITION BY O-GLCNAC TRANSFERASE
分子名称:UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit, CKII, URIDINE-5'-DIPHOSPHATE, ...
著者Jiang, J., Li, B., Hu, C.-W., Worth, M., Fan, D., Li, H.
登録日2017-04-15
公開日2017-10-18
最終更新日2017-12-06
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Electrophilic probes for deciphering substrate recognition by O-GlcNAc transferase.
Nat. Chem. Biol., 13, 2017
3DL4
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NON-AGED FORM OF MOUSE ACETYLCHOLINESTERASE INHIBITED BY TABUN- UPDATE
分子名称:Acetylcholinesterase, HEXAETHYLENE GLYCOL
著者Carletti, E., Li, H., Li, B., Ekstrom, F., Nicolet, Y., Loiodice, M., Gillon, E., Froment, M.T., Lockridge, O., Schopfer, L.M., Masson, P., Nachon, F.
登録日2008-06-26
公開日2008-12-02
最終更新日2018-03-07
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Aging of Cholinesterases Phosphylated by Tabun Proceeds through O-Dealkylation.
J.Am.Chem.Soc., 130, 2008
3DL7
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AGED FORM OF MOUSE ACETYLCHOLINESTERASE INHIBITED BY TABUN- UPDATE
分子名称:Acetylcholinesterase, N-ACETYL-D-GLUCOSAMINE, CHLORIDE ION, ...
著者Carletti, E., Li, H., Li, B., Ekstrom, F., Nicolet, Y., Loiodice, M., Gillon, E., Froment, M.T., Lockridge, O., Schopfer, L.M., Masson, P., Nachon, F.
登録日2008-06-26
公開日2008-12-02
最終更新日2018-03-07
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Aging of Cholinesterases Phosphylated by Tabun Proceeds through O-Dealkylation.
J.Am.Chem.Soc., 130, 2008
3R5S
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CRYSTAL STRUCTURE OF APO-VIUP
分子名称:Ferric vibriobactin ABC transporter, periplasmic ferric vibriobactin-binding protein
著者Li, N., Zhang, C., Li, B., Liu, X., Huang, Y., Xu, S., Gu, L.
登録日2011-03-19
公開日2012-02-08
最終更新日2012-05-30
実験手法X-RAY DIFFRACTION (1.791 Å)
主引用文献Unique iron coordination in iron-chelating molecule vibriobactin helps Vibrio cholerae evade mammalian siderocalin-mediated immune response.
J.Biol.Chem., 287, 2012