Author results

1HVB
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CRYSTAL STRUCTURE OF STREPTOMYCES R61 DD-PEPTIDASE COMPLEXED WITH A NOVEL CEPHALOSPORIN ANALOG OF CELL WALL PEPTIDOGLYCAN
Descriptor:D-ALANYL-D-ALANINE CARBOXYPEPTIDASE, 5-{3-(S)-(4-(R)-ACETYLAMINO-4-CARBOXY-BUTYRYLAMINO)-3-[1-(R)-(1-(R)-CARBOXY-ETHYLCARBAMOYL)-ETHYLCARBAMOYL]-PROPYL}-2-(CARBOXY-PHENYLACETYLAMINO-METHYL)-3,6-DIHYDRO-2H-[1,3]THIAZINE-4-CARBOXYLIC ACID
Authors:McDonough, M.A., Lee, W., Silvaggi, N.R., Mobashery, S., Kelly, J.A.
Deposit date:2001-01-08
Release date:2001-02-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.17 Å)
Cite:A 1.2-A snapshot of the final step of bacterial cell wall biosynthesis.
Proc.Natl.Acad.Sci.USA, 98, 2001
1IKG
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MICHAELIS COMPLEX OF STREPTOMYCES R61 DD-PEPTIDASE WITH A SPECIFIC PEPTIDOGLYCAN SUBSTRATE FRAGMENT
Descriptor:D-ALANYL-D-ALANINE CARBOXYPEPTIDASE, GLYCYL-L-ALPHA-AMINO-EPSILON-PIMELYL-D-ALANYL-D-ALANINE
Authors:Mcdonough, M.A., Anderson, J.W., Silvaggi, N.R., Pratt, R.F., Knox, J.R., Kelly, J.A.
Deposit date:2001-05-03
Release date:2002-09-11
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structures of two kinetic intermediates reveal species specificity of penicillin-binding proteins.
J.Mol.Biol., 322, 2002
1IKI
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COMPLEX OF STREPTOMYCES R61 DD-PEPTIDASE WITH THE PRODUCTS OF A SPECIFIC PEPTIDOGLYCAN SUBSTRATE FRAGMENT
Descriptor:D-ALANYL-D-ALANINE CARBOXYPEPTIDASE, GLYCYL-L-ALPHA-AMINO-EPSILON-PIMELYL-D-ALANINE, D-ALANINE
Authors:Mcdonough, M.A., Anderson, J.W., Silvaggi, N.R., Pratt, R.F., Knox, J.R., Kelly, J.A.
Deposit date:2001-05-03
Release date:2002-09-11
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Structures of two kinetic intermediates reveal species specificity of penicillin-binding proteins.
J.Mol.Biol., 322, 2002
1NW3
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STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN DOT1L, A NON-SET DOMAIN NUCLEOSOMAL HISTONE METHYLTRANSFERASE
Descriptor:histone methyltransferase DOT1L, ACETATE ION, SULFATE ION, ...
Authors:Min, J.R., Feng, Q., Li, Z.H., Zhang, Y., Xu, R.M.
Deposit date:2003-02-05
Release date:2003-03-25
Last modified:2014-04-16
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of the Catalytic domain of human DOT1L, a non-SET domain nucleosomal histone methyltransferase
Cell(Cambridge,Mass.), 112, 2003
1PW1
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NON-COVALENT COMPLEX OF STREPTOMYCES R61 DD-PEPTIDASE WITH A HIGHLY SPECIFIC PENICILLIN
Descriptor:D-alanyl-D-alanine carboxypeptidase, (2S,5R,6R)-6-{[(6R)-6-(GLYCYLAMINO)-7-OXIDO-7-OXOHEPTANOYL]AMINO}-3,3-DIMETHYL-7-OXO-4-THIA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLATE, GLYCEROL, ...
Authors:Silvaggi, N.R., Josephine, H.R., Pratt, R.F., Kelly, J.A.
Deposit date:2003-06-30
Release date:2004-07-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Crystal structures of complexes between the R61 DD-peptidase and peptidoglycan-mimetic beta-lactams: a non-covalent complex with a "perfect penicillin"
J.Mol.Biol., 345, 2005
1PW8
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COVALENT ACYL ENZYME COMPLEX OF THE R61 DD-PEPTIDASE WITH A HIGHLY SPECIFIC CEPHALOSPORIN
Descriptor:D-alanyl-D-alanine carboxypeptidase, (6R,7R)-3-[(ACETYLOXY)METHYL]-7-{[(6S)-6-(GLYCYLAMINO)-7-OXIDO-7-OXOHEPTANOYL]AMINO}-8-OXO-5-THIA-1-AZABICYCLO[4.2.0]OCTANE-2-CARBOXYLATE, GLYCEROL
Authors:Silvaggi, N.R., Josephine, H.R., Pratt, R.F., Kelly, J.A.
Deposit date:2003-07-01
Release date:2004-07-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Crystal structures of complexes between the R61 DD-peptidase and peptidoglycan-mimetic beta-lactams: a non-covalent complex with a "perfect penicillin"
J.Mol.Biol., 345, 2005
1PWC
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PENICILLOYL ACYL ENZYME COMPLEX OF THE STREPTOMYCES R61 DD-PEPTIDASE WITH PENICILLIN G
Descriptor:D-alanyl-D-alanine carboxypeptidase, OPEN FORM - PENICILLIN G
Authors:Silvaggi, N.R., Josephine, H.R., Pratt, R.F., Kelly, J.A.
Deposit date:2003-07-01
Release date:2004-07-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Crystal structures of complexes between the R61 DD-peptidase and peptidoglycan-mimetic beta-lactams: a non-covalent complex with a "perfect penicillin"
J.Mol.Biol., 345, 2005
1PWD
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COVALENT ACYL ENZYME COMPLEX OF THE STREPTOMYCES R61 DD-PEPTIDASE WITH CEPHALOSPORIN C
Descriptor:D-alanyl-D-alanine carboxypeptidase precursor, (2R)-5-(acetyloxymethyl)-2-[(1R)-1-[[(5R)-5-azanyl-6-oxidanyl-6-oxidanylidene-hexanoyl]amino]-2-oxidanylidene-ethyl]-5,6-dihydro-2H-1,3-thiazine-4-carboxylic acid
Authors:Silvaggi, N.R., Josephine, H.R., Pratt, R.F., Kelly, J.A.
Deposit date:2003-07-01
Release date:2004-07-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Crystal structures of complexes between the R61 DD-peptidase and peptidoglycan-mimetic beta-lactams: a non-covalent complex with a "perfect penicillin"
J.Mol.Biol., 345, 2005
1PWG
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COVALENT PENICILLOYL ACYL ENZYME COMPLEX OF THE STREPTOMYCES R61 DD-PEPTIDASE WITH A HIGHLY SPECIFIC PENICILLIN
Descriptor:D-alanyl-D-alanine carboxypeptidase, (2R,4S)-2-[(1R)-1-{[(6S)-6-carboxy-6-(glycylamino)hexanoyl]amino}-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid
Authors:Silvaggi, N.R., Josephine, H.R., Pratt, R.F., Kelly, J.A.
Deposit date:2003-07-01
Release date:2004-07-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.074 Å)
Cite:Crystal structures of complexes between the R61 DD-peptidase and peptidoglycan-mimetic beta-lactams: a non-covalent complex with a "perfect penicillin"
J.Mol.Biol., 345, 2005
3WC9
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THE COMPLEX STRUCTURE OF HSSQS WTIH LIGAND, FSPP
Descriptor:Squalene synthase, S-[(2E,6E)-3,7,11-TRIMETHYLDODECA-2,6,10-TRIENYL] TRIHYDROGEN THIODIPHOSPHATE
Authors:Shang, N., Li, Q., Ko, T.P., Chan, H.C., Huang, C.H., Ren, F., Zheng, Y., Zhu, Z., Chen, C.C., Guo, R.T.
Deposit date:2013-05-26
Release date:2014-06-18
Method:X-RAY DIFFRACTION (2.82 Å)
Cite:Squalene synthase as a target for Chagas disease therapeutics.
Plos Pathog., 10, 2014
3WCA
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THE COMPLEX STRUCTURE OF TCSQS WITH LIGAND, FSPP
Descriptor:Farnesyltransferase, putative, S-[(2E,6E)-3,7,11-TRIMETHYLDODECA-2,6,10-TRIENYL] TRIHYDROGEN THIODIPHOSPHATE, ...
Authors:Shang, N., Li, Q., Ko, T.P., Chan, H.C., Huang, C.H., Oldfield, E., Guo, R.T.
Deposit date:2013-05-26
Release date:2014-06-18
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:Squalene synthase as a target for Chagas disease therapeutics.
Plos Pathog., 10, 2014
3WCB
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THE COMPLEX STRUCTURE OF TCSQS WITH LIGAND, BPH1237
Descriptor:Farnesyltransferase, putative, hydrogen [(1R)-2-(3-decyl-1H-imidazol-3-ium-1-yl)-1-hydroxy-1-phosphonoethyl]phosphonate
Authors:Shang, N., Li, Q., Ko, T.P., Chan, H.C., Huang, C.H., Ren, F., Zheng, Y., Zhu, Z., Chen, C.C., Guo, R.T.
Deposit date:2013-05-27
Release date:2014-06-18
Method:X-RAY DIFFRACTION (3 Å)
Cite:Squalene synthase as a target for Chagas disease therapeutics.
Plos Pathog., 10, 2014
3WCC
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THE COMPLEX STRUCTURE OF TCSQS WITH LIGAND, E5700
Descriptor:Farnesyltransferase, putative, (3R)-3-({2-benzyl-6-[(3R,4S)-3-hydroxy-4-methoxypyrrolidin-1-yl]pyridin-3-yl}ethynyl)-1-azabicyclo[2.2.2]octan-3-ol
Authors:Shang, N., Li, Q., Ko, T.P., Chan, H.C., Huang, C.H., Ren, F., Zheng, Y., Zhu, Z., Chen, C.C., Guo, R.T.
Deposit date:2013-05-27
Release date:2014-06-18
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:Squalene synthase as a target for Chagas disease therapeutics.
Plos Pathog., 10, 2014
3WCD
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THE COMPLEX STRUCTURE OF HSSQS WTIH LIGAND, WC-9
Descriptor:Squalene synthase, 2-(4-phenoxyphenoxy)ethyl thiocyanate
Authors:Shang, N., Li, Q., Ko, T.P., Chan, H.C., Huang, C.H., Ren, F., Zheng, Y., Zhu, Z., Chen, C.C., Guo, R.T.
Deposit date:2013-05-27
Release date:2014-06-18
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Squalene synthase as a target for Chagas disease therapeutics.
Plos Pathog., 10, 2014
3WCE
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THE COMPLEX STRUCTURE OF TCSQS WITH LIGAND, ER119884
Descriptor:Farnesyltransferase, putative, (3R)-3-{[2-benzyl-6-(3-methoxypropoxy)pyridin-3-yl]ethynyl}-1-azabicyclo[2.2.2]octan-3-ol
Authors:Shang, N., Li, Q., Ko, T.P., Chan, H.C., Huang, C.H., Ren, F., Zheng, Y., Zhu, Z., Chen, C.C., Guo, R.T.
Deposit date:2013-05-27
Release date:2014-06-18
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Squalene synthase as a target for Chagas disease therapeutics.
Plos Pathog., 10, 2014
3WCF
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THE COMPLEX STRUCTURE OF HSSQS WTIH LIGAND,BPH1218
Descriptor:Squalene synthase, hydrogen [(1S)-2-(3-decyl-1H-imidazol-3-ium-1-yl)-1-phosphonoethyl]phosphonate
Authors:Shang, N., Li, Q., Ko, T.P., Chan, H.C., Huang, C.H., Ren, F., Zheng, Y., Zhu, Z., Chen, C.C., Guo, R.T.
Deposit date:2013-05-27
Release date:2014-06-18
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Squalene synthase as a target for Chagas disease therapeutics.
Plos Pathog., 10, 2014
3WCG
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THE COMPLEX STRUCTURE OF TCSQS WITH LIGAND, BPH1344
Descriptor:Farnesyltransferase, putative, hydrogen [(1R)-2-(3-pentadecyl-1H-imidazol-3-ium-1-yl)-1-phosphonoethyl]phosphonate
Authors:Shang, N., Li, Q., Ko, T.P., Chan, H.C., Huang, C.H., Ren, F., Zheng, Y., Zhu, Z., Chen, C.C., Guo, R.T.
Deposit date:2013-05-27
Release date:2014-06-18
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Squalene synthase as a target for Chagas disease therapeutics.
Plos Pathog., 10, 2014
3WCH
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THE COMPLEX STRUCTURE OF HSSQS WTIH LIGAND BPH1237
Descriptor:Squalene synthase, hydrogen [(1R)-2-(3-decyl-1H-imidazol-3-ium-1-yl)-1-hydroxy-1-phosphonoethyl]phosphonate
Authors:Shang, N., Li, Q., Ko, T.P., Chan, H.C., Huang, C.H., Ren, F., Zheng, Y., Zhu, Z., Chen, C.C., Guo, R.T.
Deposit date:2013-05-27
Release date:2014-06-18
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Squalene synthase as a target for Chagas disease therapeutics.
Plos Pathog., 10, 2014
3WCI
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THE COMPLEX STRUCTURE OF HSSQS WTIH LIGAND,BPH1325
Descriptor:Squalene synthase, hydrogen [(1R)-1-hydroxy-2-(3-pentadecyl-1H-imidazol-3-ium-1-yl)-1-phosphonoethyl]phosphonate
Authors:Shang, N., Li, Q., Ko, T.P., Chan, H.C., Huang, C.H., Ren, F., Zheng, Y., Zhu, Z., Chen, C.C., Guo, R.T.
Deposit date:2013-05-27
Release date:2014-06-18
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Squalene synthase as a target for Chagas disease therapeutics.
Plos Pathog., 10, 2014
3WCJ
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THE COMPLEX STRUCTURE OF HSSQS WTIH LIGAND,E5700
Descriptor:Squalene synthase, (3R)-3-({2-benzyl-6-[(3R,4S)-3-hydroxy-4-methoxypyrrolidin-1-yl]pyridin-3-yl}ethynyl)-1-azabicyclo[2.2.2]octan-3-ol
Authors:Shang, N., Li, Q., Ko, T.P., Chan, H.C., Huang, C.H., Ren, F., Zheng, Y., Zhu, Z., Chen, C.C., Guo, R.T.
Deposit date:2013-05-27
Release date:2014-06-18
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Squalene synthase as a target for Chagas disease therapeutics.
Plos Pathog., 10, 2014
3WCL
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THE COMPLEX STRUCTURE OF HSSQS WTIH LIGAND,BPH1344
Descriptor:Squalene synthase, hydrogen [(1R)-2-(3-pentadecyl-1H-imidazol-3-ium-1-yl)-1-phosphonoethyl]phosphonate
Authors:Shang, N., Li, Q., Ko, T.P., Chan, H.C., Huang, C.H., Ren, F., Zheng, Y., Zhu, Z., Chen, C.C., Guo, R.T.
Deposit date:2013-05-28
Release date:2014-06-18
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:Squalene synthase as a target for Chagas disease therapeutics.
Plos Pathog., 10, 2014
3WCM
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THE COMPLEX STRUCTURE OF HSSQS WTIH LIGAND, ER119884
Descriptor:Squalene synthase, (3R)-3-{[2-benzyl-6-(3-methoxypropoxy)pyridin-3-yl]ethynyl}-1-azabicyclo[2.2.2]octan-3-ol
Authors:Shang, N., Li, Q., Ko, T.P., Chan, H.C., Huang, C.H., Ren, F., Zheng, Y., Zhu, Z., Chen, C.C., Guo, R.T.
Deposit date:2013-05-28
Release date:2014-06-18
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Squalene synthase as a target for Chagas disease therapeutics.
Plos Pathog., 10, 2014
5J6R
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CRYSTAL STRUCTURE OF HUMAN PAPILLOMAVIRUS TYPE 59 L1 PENTAMER
Descriptor:Major capsid protein L1
Authors:Li, Z.H., Yan, X.D., Yu, H., Gu, Y., Li, S.W.
Deposit date:2016-04-05
Release date:2016-05-18
Last modified:2016-07-06
Method:X-RAY DIFFRACTION (4.011 Å)
Cite:The C-Terminal Arm of the Human Papillomavirus Major Capsid Protein Is Immunogenic and Involved in Virus-Host Interaction.
Structure, 24, 2016
5JB1
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PSEUDO-ATOMIC STRUCTURE OF HUMAN PAPILLOMAVIRUS TYPE 59 L1 VIRUS-LIKE PARTICLE
Descriptor:Major capsid protein L1
Authors:Li, Z.H., Yan, X.D., Yu, H., Zheng, Q.B., Gu, Y., Li, S.W.
Deposit date:2016-04-13
Release date:2016-05-18
Last modified:2017-10-18
Method:ELECTRON MICROSCOPY (6 Å)
Cite:The C-Terminal Arm of the Human Papillomavirus Major Capsid Protein Is Immunogenic and Involved in Virus-Host Interaction.
Structure, 24, 2016
5TC1
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IN SITU STRUCTURES OF THE GENOME AND GENOME-DELIVERY APPARATUS IN SSRNA BACTERIOPHAGE MS2
Descriptor:Capsid protein, Maturation protein, phage MS2 genome
Authors:Dai, X.H., Li, Z.H., Lai, M., Shu, S., Du, Y.S., Zhou, Z.H., Sun, R.
Deposit date:2016-09-13
Release date:2016-12-07
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:In situ structures of the genome and genome-delivery apparatus in a single-stranded RNA virus.
Nature, 541, 2017
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