Author results

6P7I
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CRYSTAL STRUCTURE OF HUMAN PRMT6 IN COMPLEX WITH S-ADENOSYL-L-HOMOCYSTEINE AND YS17-117 COMPOUND
Descriptor:Protein arginine N-methyltransferase 6, S-ADENOSYL-L-HOMOCYSTEINE, N-[3-(4-{[(2-aminoethyl)(methyl)amino]methyl}-1H-pyrrol-3-yl)phenyl]prop-2-enamide, ...
Authors:Halabelian, L., Dong, A., Zeng, H., Li, Y., Seitova, A., Hutchinson, A., Bountra, C., Edwards, A.M., Arrowsmith, C.H., Brown, P.J., Structural Genomics Consortium (SGC)
Deposit date:2019-06-05
Release date:2019-06-26
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of Human PRMT6 in complex with S-Adenosyl-L-Homocysteine and YS17-117 Comp ound
to be published
6A38
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MVM NS2 NES IN COMPLEX WITH CRM1-RAN-RANBP1
Descriptor:GTP-binding nuclear protein Ran, Ran-specific GTPase-activating protein 1, Exportin-1, ...
Authors:Sun, Q., Li, Y.
Deposit date:2018-06-15
Release date:2019-06-19
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:MVM NS2 NES in complex with CRM1-Ran-RanBP1
To Be Published
6A3A
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MVM NES MUTANT NM2 IN COMPLEX WITH CRM1-RAN-RANBP1
Descriptor:GTP-binding nuclear protein Ran, Ran-specific GTPase-activating protein 1, Exportin-1, ...
Authors:Sun, Q., Li, Y.
Deposit date:2018-06-15
Release date:2019-06-19
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Mm2 in complex with CRM1-Ran-RanBP1
To Be Published
6A3B
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MVM NES MUTANT NM13 IN COMPLEX WITH CRM1-RAN-RANBP1
Descriptor:GTP-binding nuclear protein Ran, Ran-specific GTPase-activating protein 1, Exportin-1, ...
Authors:Sun, Q., Li, Y.
Deposit date:2018-06-15
Release date:2019-06-19
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Mm12 in complex with CRM1-Ran-RanBP1
To Be Published
6A3C
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MVM NES MUTANT NM12 IN COMPLEX WITH CRM1-RAN-RANBP1
Descriptor:GTP-binding nuclear protein Ran, Ran-specific GTPase-activating protein 1, Exportin-1, ...
Authors:Sun, Q., Li, Y.
Deposit date:2018-06-15
Release date:2019-06-19
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:MVM NS2 NES in complex with CRM1-Ran-RanBP1
To Be Published
6A3E
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MVM NES MUTANT NM15 IN COMPLEX WITH CRM1-RAN-RANBP1
Descriptor:GTP-binding nuclear protein Ran, Ran-specific GTPase-activating protein 1, Exportin-1, ...
Authors:Sun, Q., Li, Y.
Deposit date:2018-06-15
Release date:2019-06-19
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Mm15 in complex with CRM1-Ran-RanBP1
To Be Published
6A4C
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SOLUTION STRUCTURE OF MXAN_0049
Descriptor:Uncharacterized protein MXAN_0049
Authors:Chen, C., Feng, Y.
Deposit date:2018-06-19
Release date:2019-06-19
Method:SOLUTION NMR
Cite:Solution structure of MXAN_0049
To Be Published
6IV8
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THE SELENOMETHIONINE(SEMET)-DERIVED CAS13D BINARY COMPLEX
Descriptor:The selenomethionine (SeMet)-labeled Cas13d, RNA (51-MER), RNA (53-MER), ...
Authors:Zhang, B., Ye, Y.M., Ye, W.W., OuYang, S.Y.
Deposit date:2018-12-02
Release date:2019-06-19
Last modified:2019-06-26
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Two HEPN domains dictate CRISPR RNA maturation and target cleavage in Cas13d.
Nat Commun, 10, 2019
6IV9
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THE CAS13D BINARY COMPLEX
Descriptor:Cas13d, crRNA (50-MER), MAGNESIUM ION
Authors:Zhang, B., Ye, Y.M., Ye, W.W., OuYang, S.Y.
Deposit date:2018-12-02
Release date:2019-06-19
Last modified:2019-06-26
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Two HEPN domains dictate CRISPR RNA maturation and target cleavage in Cas13d.
Nat Commun, 10, 2019
6P0Q
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CRYSTAL STRUCTURE OF UBIQUITIN-LIKE DOMAIN OF HUMAN WDR12
Descriptor:Ribosome biogenesis protein WDR12, 1,2-ETHANEDIOL
Authors:Halabelian, L., Dong, A., Zeng, H., Li, Y., Bountra, C., Edwards, A.M., Arrowsmith, C.H., Structural Genomics Consortium (SGC)
Deposit date:2019-05-17
Release date:2019-05-29
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Crystal Structure of Ubiquitin-like Domain of Human WDR12
to be published
6BOF
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CRYSTAL STRUCTURE OF KRAS A146T-GDP DEMONSTRATING OPEN SWITCH 1 CONFORMATION
Descriptor:GTPase KRas, GUANOSINE-5'-DIPHOSPHATE
Authors:Bera, A.K., Yan, W., Westover, K.D.
Deposit date:2017-11-20
Release date:2019-05-22
Last modified:2019-06-19
Method:X-RAY DIFFRACTION (1.401 Å)
Cite:Tissue-Specific Oncogenic Activity of KRASA146T.
Cancer Discov, 9, 2019
6O59
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CRYSTAL STRUCTURE OF THE N-TERMINAL DOMAIN OF THE A SUBUNIT OF THE BACILLUS MEGATERIUM SPORE GERMINANT RECEPTOR GERK3
Descriptor:Germination protein
Authors:Li, Y., Hao, B.
Deposit date:2019-03-01
Release date:2019-05-22
Last modified:2019-06-12
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:Structural and functional analyses of the N-terminal domain of the A subunit of aBacillus megateriumspore germinant receptor.
Proc.Natl.Acad.Sci.USA, 116, 2019
6OVC
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HMCL1 INHIBITOR COMPLEX
Descriptor:Induced myeloid leukemia cell differentiation protein Mcl-1, (2S)-N-(benzylsulfonyl)-4-(cyclobutylmethyl)-2-(2,4-dichlorophenyl)-3,4-dihydro-2H-1,4-benzoxazine-6-carboxamide
Authors:Poppe, L.
Deposit date:2019-05-07
Release date:2019-05-22
Method:SOLUTION NMR
Cite:AMG 176, a Selective MCL1 Inhibitor, Is Effective in Hematologic Cancer Models Alone and in Combination with Established Therapies.
Cancer Discov, 8, 2018
6ILJ
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CRYO-EM STRUCTURE OF ECHOVIRUS 6 COMPLEXED WITH ITS ATTACHMENT RECEPTOR CD55 AT PH 5.5
Descriptor:Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ...
Authors:Gao, G.F., Liu, S., Zhao, X., Peng, R.
Deposit date:2018-10-18
Release date:2019-05-15
Last modified:2019-06-12
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Human Neonatal Fc Receptor Is the Cellular Uncoating Receptor for Enterovirus B.
Cell, 177, 2019
6ILK
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CRYO-EM STRUCTURE OF ECHOVIRUS 6 COMPLEXED WITH ITS ATTACHMENT RECEPTOR CD55 AT PH 7.4
Descriptor:Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ...
Authors:Gao, G.F., Liu, S., Zhao, X., Peng, R.
Deposit date:2018-10-18
Release date:2019-05-15
Last modified:2019-06-12
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Human Neonatal Fc Receptor Is the Cellular Uncoating Receptor for Enterovirus B.
Cell, 177, 2019
6ILL
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CRYO-EM STRUCTURE OF ECHOVIRUS 6 COMPLEXED WITH ITS UNCOATING RECEPTOR FCRN AT PH 5.5
Descriptor:Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ...
Authors:Gao, G.F., Liu, S., Zhao, X., Peng, R.
Deposit date:2018-10-19
Release date:2019-05-15
Last modified:2019-06-12
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Human Neonatal Fc Receptor Is the Cellular Uncoating Receptor for Enterovirus B.
Cell, 177, 2019
6ILM
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CRYO-EM STRUCTURE OF ECHOVIRUS 6 COMPLEXED WITH ITS UNCOATING RECEPTOR FCRN AT PH 7.4
Descriptor:Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ...
Authors:Gao, G.F., Liu, S., Zhao, X., Peng, R.
Deposit date:2018-10-19
Release date:2019-05-15
Last modified:2019-06-12
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Human Neonatal Fc Receptor Is the Cellular Uncoating Receptor for Enterovirus B.
Cell, 177, 2019
6ILN
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CRYO-EM STRUCTURE OF FULL ECHOVIRUS 6 PARTICLE AT PH 5.5
Descriptor:Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ...
Authors:Gao, G.F., Liu, S., Zhao, X., Peng, R.
Deposit date:2018-10-19
Release date:2019-05-15
Last modified:2019-06-12
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Human Neonatal Fc Receptor Is the Cellular Uncoating Receptor for Enterovirus B.
Cell, 177, 2019
6ILO
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CRYO-EM STRUCTURE OF EMPTY ECHOVIRUS 6 PARTICLE AT PH 7.4
Descriptor:Capsid protein VP1, Capsid protein VP2, Capsid protein VP3
Authors:Gao, G.F., Liu, S., Zhao, X., Peng, R.
Deposit date:2018-10-19
Release date:2019-05-15
Last modified:2019-06-12
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Human Neonatal Fc Receptor Is the Cellular Uncoating Receptor for Enterovirus B.
Cell, 177, 2019
6ILP
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CRYO-EM STRUCTURE OF FULL ECHOVIRUS 6 PARTICLE AT PH 7.4
Descriptor:Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ...
Authors:Gao, G.F., Liu, S., Zhao, X., Peng, R.
Deposit date:2018-10-19
Release date:2019-05-15
Last modified:2019-06-12
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Human Neonatal Fc Receptor Is the Cellular Uncoating Receptor for Enterovirus B.
Cell, 177, 2019
6IVS
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SOLUTION STRUCTURE OF THE N-TERMINAL DOMAIN OF THE ANTI-SIGMA FACTOR RSGI1 FROM CLOSTRIDIUM THERMOCELLUM
Descriptor:Anti-sigma-I factor RsgI1
Authors:Wei, Z., Feng, Y.
Deposit date:2018-12-04
Release date:2019-05-15
Last modified:2019-07-03
Method:SOLUTION NMR
Cite:Alternative sigma I/anti-sigma I factors represent a unique form of bacterial sigma /anti-sigma complex.
Nucleic Acids Res., 47, 2019
6IVU
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SOLUTION STRUCTURE OF THE SIGMA-ANTI-SIGMA FACTOR COMPLEX RSGI1N-SIGI1C FROM CLOSTRIDIUM THERMOCELLUM
Descriptor:Anti-sigma-I factor RsgI1, RNA polymerase sigma factor SigI1
Authors:Wei, Z., Feng, Y.
Deposit date:2018-12-04
Release date:2019-05-15
Last modified:2019-07-03
Method:SOLUTION NMR
Cite:Alternative sigma I/anti-sigma I factors represent a unique form of bacterial sigma /anti-sigma complex.
Nucleic Acids Res., 47, 2019
6MRT
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12-MERIC CLYA PORE COMPLEX
Descriptor:Hemolysin E, chromosomal
Authors:Peng, W., de Souza Santos, M., Li, Y., Tomchick, D.R., Orth, K.
Deposit date:2018-10-15
Release date:2019-05-15
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:High-resolution cryo-EM structures of the E. coli hemolysin ClyA oligomers.
Plos One, 14, 2019
6MRU
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13-MERIC CLYA PORE COMPLEX
Descriptor:Hemolysin E, chromosomal
Authors:Peng, W., de Souza Santos, M., Li, Y., Tomchick, D.R., Orth, K.
Deposit date:2018-10-15
Release date:2019-05-15
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:High-resolution cryo-EM structures of the E. coli hemolysin ClyA oligomers.
Plos One, 14, 2019
6MRW
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14-MERIC CLYA PORE COMPLEX
Descriptor:Hemolysin E, chromosomal
Authors:Peng, W., de Souza Santos, M., Li, Y., Tomchick, D.R., Orth, K.
Deposit date:2018-10-15
Release date:2019-05-15
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:High-resolution cryo-EM structures of the E. coli hemolysin ClyA oligomers.
Plos One, 14, 2019