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5KTQ
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BU of 5ktq by Molmil
LARGE FRAGMENT OF TAQ DNA POLYMERASE BOUND TO DCTP
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, PROTEIN (DNA POLYMERASE I)
Authors:Li, Y, Kong, Y, Korolev, S, Waksman, G.
Deposit date:1998-09-22
Release date:1998-09-30
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structures of the Klenow fragment of Thermus aquaticus DNA polymerase I complexed with deoxyribonucleoside triphosphates.
Protein Sci., 7, 1998
7BV6
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BU of 7bv6 by Molmil
Crystal structure of the autophagic STX17/SNAP29/VAMP8 SNARE complex
Descriptor: Synaptosomal-associated protein 29, Syntaxin-17, Vesicle-associated membrane protein 8
Authors:Li, Y, Pan, L.F.
Deposit date:2020-04-09
Release date:2020-09-02
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Decoding three distinct states of the Syntaxin17 SNARE motif in mediating autophagosome-lysosome fusion.
Proc.Natl.Acad.Sci.USA, 117, 2020
7BV4
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BU of 7bv4 by Molmil
Crystal structure of STX17 LIR region in complex with GABARAP
Descriptor: DI(HYDROXYETHYL)ETHER, GLYCEROL, Gamma-aminobutyric acid receptor-associated protein, ...
Authors:Li, Y, Pan, L.F.
Deposit date:2020-04-09
Release date:2020-09-02
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Decoding three distinct states of the Syntaxin17 SNARE motif in mediating autophagosome-lysosome fusion.
Proc.Natl.Acad.Sci.USA, 117, 2020
5F59
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BU of 5f59 by Molmil
The crystal structure of MLL3 SET domain
Descriptor: Histone-lysine N-methyltransferase 2C, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION
Authors:Li, Y, Lei, M, Chen, Y.
Deposit date:2015-12-04
Release date:2016-02-24
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.801 Å)
Cite:Structural basis for activity regulation of MLL family methyltransferases.
Nature, 530, 2016
5F6L
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BU of 5f6l by Molmil
The crystal structure of MLL1 (N3861I/Q3867L) in complex with RbBP5 and Ash2L
Descriptor: Histone-lysine N-methyltransferase 2A, Retinoblastoma-binding protein 5, S-ADENOSYL-L-HOMOCYSTEINE, ...
Authors:Li, Y, Lei, M, Chen, Y.
Deposit date:2015-12-06
Release date:2016-02-24
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for activity regulation of MLL family methyltransferases.
Nature, 530, 2016
5F5E
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BU of 5f5e by Molmil
The Crystal Structure of MLL1 SET domain with N3816I/Q3867L mutation
Descriptor: Histone-lysine N-methyltransferase 2A, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION
Authors:Li, Y, Lei, M, Chen, Y.
Deposit date:2015-12-04
Release date:2016-02-24
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.802 Å)
Cite:Structural basis for activity regulation of MLL family methyltransferases.
Nature, 530, 2016
5F6K
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BU of 5f6k by Molmil
Crystal structure of the MLL3-Ash2L-RbBP5 complex
Descriptor: Histone-lysine N-methyltransferase 2C, Retinoblastoma-binding protein 5, S-ADENOSYL-L-HOMOCYSTEINE, ...
Authors:Li, Y, Lei, M, Chen, Y.
Deposit date:2015-12-06
Release date:2016-02-24
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.411 Å)
Cite:Structural basis for activity regulation of MLL family methyltransferases.
Nature, 530, 2016
1HQR
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BU of 1hqr by Molmil
CRYSTAL STRUCTURE OF A SUPERANTIGEN BOUND TO THE HIGH-AFFINITY, ZINC-DEPENDENT SITE ON MHC CLASS II
Descriptor: HLA-DR ALPHA CHAIN, HLA-DR BETA CHAIN, MYELIN BASIC PROTEIN, ...
Authors:Li, Y, Li, H, Dimasi, N, Schlievert, P, Mariuzza, R.
Deposit date:2000-12-19
Release date:2001-01-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structure of a superantigen bound to the high-affinity, zinc-dependent site on MHC class II.
Immunity, 14, 2001
8GZ1
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BU of 8gz1 by Molmil
Cryo-EM structure of human NaV1.6/beta1/beta2,apo state
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, SODIUM ION, Sodium channel protein type 8 subunit alpha, ...
Authors:Li, Y, Jiang, D.
Deposit date:2022-09-24
Release date:2023-03-08
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure of human Na V 1.6 channel reveals Na + selectivity and pore blockade by 4,9-anhydro-tetrodotoxin.
Nat Commun, 14, 2023
8GZ2
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BU of 8gz2 by Molmil
Cryo-EM structure of human NaV1.6/beta1/beta2-4,9-anhydro-tetrodotoxin
Descriptor: (1R,2S,3S,4R,5R,9S,11S,12S,14R)-7-amino-2,4,12-trihydroxy-2-(hydroxymethyl)-10,13,15-trioxa-6,8-diazapentacyclo[7.4.1.1~3,12~.0~5,11~.0~5,14~]pentadec-7-en-8-ium (non-preferred name), 2-acetamido-2-deoxy-beta-D-glucopyranose, Sodium channel protein type 8 subunit alpha, ...
Authors:Li, Y, Jiang, D.
Deposit date:2022-09-24
Release date:2023-03-08
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structure of human Na V 1.6 channel reveals Na + selectivity and pore blockade by 4,9-anhydro-tetrodotoxin.
Nat Commun, 14, 2023
7SOY
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BU of 7soy by Molmil
The structure of the PP2A-B56gamma1 holoenzyme-PME-1 complex
Descriptor: Isoform Gamma-1 of Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform, Protein phosphatase methylesterase 1, Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, ...
Authors:Li, Y, Balakrishnan, V.K, Rowse, M, Novikova, I.V, Xing, Y.
Deposit date:2021-11-01
Release date:2022-08-31
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Coupling to short linear motifs creates versatile PME-1 activities in PP2A holoenzyme demethylation and inhibition.
Elife, 11, 2022
8GPX
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BU of 8gpx by Molmil
YFV_E_YD73Fab_postfusion
Descriptor: Envelope protein, YD73Fab_H, YD73Fab_K
Authors:Li, Y, Wu, L, Chai, Y, Qi, J, Yan, J, Gao, G.F.
Deposit date:2022-08-27
Release date:2022-11-02
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:A neutralizing-protective supersite of human monoclonal antibodies for yellow fever virus.
Innovation (N Y), 3, 2022
7BRE
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BU of 7bre by Molmil
The crystal structure of MLL2 in complex with ASH2L and RBBP5
Descriptor: Histone-lysine N-methyltransferase 2B, Retinoblastoma-binding protein 5, S-ADENOSYL-L-HOMOCYSTEINE, ...
Authors:Li, Y, Zhao, L, Chen, Y.
Deposit date:2020-03-28
Release date:2020-07-22
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.803 Å)
Cite:Crystal Structure of MLL2 Complex Guides the Identification of a Methylation Site on P53 Catalyzed by KMT2 Family Methyltransferases.
Structure, 28, 2020
1QSY
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BU of 1qsy by Molmil
DDATP-Trapped closed ternary complex of the large fragment of DNA Polymerase I from thermus aquaticus
Descriptor: 2',3'-dideoxyadenosine triphosphate, 5'-D(*AP*TP*TP*GP*CP*GP*CP*CP*TP*P*GP*GP*TP*C)-3', 5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(2DA))-3', ...
Authors:Li, Y, Mitaxov, V, Waksman, G.
Deposit date:1999-06-24
Release date:1999-08-16
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure-based design of Taq DNA polymerases with improved properties of dideoxynucleotide incorporation.
Proc.Natl.Acad.Sci.USA, 96, 1999
1QSS
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BU of 1qss by Molmil
DDGTP-TRAPPED CLOSED TERNARY COMPLEX OF THE LARGE FRAGMENT OF DNA POLYMERASE I FROM THERMUS AQUATICUS
Descriptor: 2'-3'-DIDEOXYGUANOSINE-5'-TRIPHOSPHATE, 5'-D(*AP*CP*CP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3', 5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DDG))-3', ...
Authors:Li, Y, Mitaxov, V, Waksman, G.
Deposit date:1999-06-23
Release date:1999-08-16
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure-based design of Taq DNA polymerases with improved properties of dideoxynucleotide incorporation.
Proc.Natl.Acad.Sci.USA, 96, 1999
1QTM
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BU of 1qtm by Molmil
DDTTP-TRAPPED CLOSED TERNARY COMPLEX OF THE LARGE FRAGMENT OF DNA POLYMERASE I FROM THERMUS AQUATICUS
Descriptor: 5'-D(*AP*AP*AP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3', 5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(2DT))-3', DNA POLYMERASE I, ...
Authors:Li, Y, Mitaxov, V, Waksman, G.
Deposit date:1999-06-28
Release date:1999-08-16
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure-based design of Taq DNA polymerases with improved properties of dideoxynucleotide incorporation.
Proc.Natl.Acad.Sci.USA, 96, 1999
2N7G
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BU of 2n7g by Molmil
Structure of the cyclic nucleotide-binding homology domain of the hERG channel
Descriptor: Potassium voltage-gated channel subfamily H member 2
Authors:Li, Y, Ng, H, Li, Q, Kang, C.
Deposit date:2015-09-10
Release date:2016-05-18
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structure of the Cyclic Nucleotide-Binding Homology Domain of the hERG Channel and Its Insight into Type 2 Long QT Syndrome
Sci Rep, 6, 2016
2N7R
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BU of 2n7r by Molmil
Structure of the transmembrane domain of human nicastrin in DPC micelles
Descriptor: Nicastrin
Authors:Li, Y, Liew, L, Li, Q, Kang, C.
Deposit date:2015-09-17
Release date:2016-04-27
Method:SOLUTION NMR
Cite:Structure of the transmembrane domain of human nicastrin-a component of gamma-secretase
Sci Rep, 6, 2016
1DTL
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BU of 1dtl by Molmil
CRYSTAL STRUCTURE OF CALCIUM-SATURATED (3CA2+) CARDIAC TROPONIN C COMPLEXED WITH THE CALCIUM SENSITIZER BEPRIDIL AT 2.15 A RESOLUTION
Descriptor: 1-ISOBUTOXY-2-PYRROLIDINO-3[N-BENZYLANILINO] PROPANE, CALCIUM ION, CARDIAC TROPONIN C
Authors:Li, Y, Love, M.L, Putkey, J.A, Cohen, C.
Deposit date:2000-01-12
Release date:2000-05-12
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Bepridil opens the regulatory N-terminal lobe of cardiac troponin C.
Proc.Natl.Acad.Sci.USA, 97, 2000
2N7Q
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BU of 2n7q by Molmil
Structure of the transmembrane domain of human nicastrin in SDS micelles
Descriptor: Nicastrin
Authors:Li, Y, Liew, L, Li, Q, Kang, C.
Deposit date:2015-09-17
Release date:2016-04-27
Method:SOLUTION NMR
Cite:Structure of the transmembrane domain of human nicastrin-a component of gamma-secretase
Sci Rep, 6, 2016
8GPT
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BU of 8gpt by Molmil
YFV_E_YD6scFv_postfusion
Descriptor: Envelope protein, YD6_VH, YD6_VL
Authors:Li, Y, Wu, L, Qi, J, Yan, J, Gao, G.F.
Deposit date:2022-08-27
Release date:2022-11-02
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.07 Å)
Cite:A neutralizing-protective supersite of human monoclonal antibodies for yellow fever virus.
Innovation (N Y), 3, 2022
8GPU
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BU of 8gpu by Molmil
YFV_E_YD6Fab_prefusion
Descriptor: Envelope protein, YD6Fab_H, YD6Fab_L
Authors:Li, Y, Wu, L, Qi, J, Yan, J, Gao, G.F.
Deposit date:2022-08-27
Release date:2022-11-02
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:A neutralizing-protective supersite of human monoclonal antibodies for yellow fever virus.
Innovation (N Y), 3, 2022
6O59
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BU of 6o59 by Molmil
Crystal structure of the N-terminal domain of the A subunit of the Bacillus megaterium spore germinant receptor GerK3
Descriptor: Germination protein
Authors:Li, Y, Hao, B.
Deposit date:2019-03-01
Release date:2019-05-22
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:Structural and functional analyses of the N-terminal domain of the A subunit of aBacillus megateriumspore germinant receptor.
Proc.Natl.Acad.Sci.USA, 116, 2019
6QNX
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BU of 6qnx by Molmil
Structure of the SA2/SCC1/CTCF complex
Descriptor: Cohesin subunit SA-2, Double-strand-break repair protein rad21 homolog, Transcriptional repressor CTCF
Authors:Li, Y, Muir, K.W, Panne, D.
Deposit date:2019-02-12
Release date:2020-01-22
Last modified:2020-04-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The structural basis for cohesin-CTCF-anchored loops.
Nature, 578, 2020
5VHG
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BU of 5vhg by Molmil
Crystal structure of pentad mutant GAPR-1
Descriptor: Golgi-associated plant pathogenesis-related protein 1, SULFATE ION
Authors:Li, Y, Zhao, Y, Su, M, Chakravarthy, S, Colbert, C.L, Levine, B, Sinha, S.C.
Deposit date:2017-04-13
Release date:2017-09-20
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.27 Å)
Cite:Structural insights into the interaction of the conserved mammalian proteins GAPR-1 and Beclin 1, a key autophagy protein.
Acta Crystallogr D Struct Biol, 73, 2017

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