Author results

1AKH
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MAT A1/ALPHA2/DNA TERNARY COMPLEX
Descriptor:DNA (5'-D(*TP*AP*CP*AP*TP*GP*TP*AP*AP*AP*AP*AP*TP*TP*TP*AP*C P*AP*TP*CP*A)-3'), DNA (5'-D(*TP*AP*TP*GP*AP*TP*GP*TP*AP*AP*AP*TP*TP*TP*TP*TP*A P*CP*AP*TP*G)-3'), PROTEIN (MATING-TYPE PROTEIN A-1), ...
Authors:Li, T., Jin, Y., Vershon, A.K., Wolberger, C.
Deposit date:1997-05-19
Release date:1998-05-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the MATa1/MATalpha2 homeodomain heterodimer in complex with DNA containing an A-tract.
Nucleic Acids Res., 26, 1998
1KU5
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CRYSTAL STRUCTURE OF RECOMBINANT HISTONE HPHA FROM HYPERTHERMOPHILIC ARCHAEON PYROCOCCUS HORIKOSHII OT3
Descriptor:HPhA, ACETATE ION, SULFATE ION
Authors:Li, T., Sun, F., Ji, X., Feng, Y., Rao, Z.
Deposit date:2002-01-21
Release date:2003-08-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure based hyperthermostability of archaeal histone HPhA from Pyrococcus horikoshii
J.MOL.BIOL., 325, 2003
1YRN
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CRYSTAL STRUCTURE OF THE MATA1/MATALPHA2 HOMEODOMAIN HETERODIMER BOUND TO DNA
Descriptor:DNA (5'-D(*TP*AP*CP*AP*TP*GP*TP*AP*AP*TP*TP*TP*AP*TP*TP*AP*C P*AP*TP*CP*A)-3'), DNA (5'-D(*TP*AP*TP*GP*AP*TP*GP*TP*AP*AP*TP*AP*AP*AP*TP*TP*A P*CP*AP*TP*G)-3'), PROTEIN (MAT A1 HOMEODOMAIN), ...
Authors:Li, T., Stark, M.R., Johnson, A.D., Wolberger, C.
Deposit date:1995-11-02
Release date:1996-01-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the MATa1/MAT alpha 2 homeodomain heterodimer bound to DNA.
Science, 270, 1995
5Z0R
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STRUCTURAL INSIGHT INTO THE ZIKA VIRUS CAPSID ENCAPSULATING THE VIRAL GENOME
Descriptor:Extracellular solute-binding protein family 1,viral genome protein, MALTOSE
Authors:Li, T., Zhao, Q., Yang, X., Chen, C., Yang, K., Wu, C., Zhang, T., Duan, Y., Xue, X., Mi, K., Ji, X., Wang, Z., Yang, H.
Deposit date:2017-12-20
Release date:2018-04-11
Last modified:2018-05-02
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural insight into the Zika virus capsid encapsulating the viral genome.
Cell Res., 28, 2018
5Z0V
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STRUCTURAL INSIGHT INTO THE ZIKA VIRUS CAPSID ENCAPSULATING THE VIRAL GENOME
Descriptor:Extracellular solute-binding protein family 1,viral genome protein, MALTOSE
Authors:Li, T., Zhao, Q., Yang, X., Chen, C., Yang, K., Wu, C., Zhang, T., Duan, Y., Xue, X., Mi, K., Ji, X., Wang, Z., Yang, H.
Deposit date:2017-12-21
Release date:2018-04-11
Last modified:2018-05-02
Method:X-RAY DIFFRACTION (2.913 Å)
Cite:Structural insight into the Zika virus capsid encapsulating the viral genome.
Cell Res., 28, 2018
1MYM
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STRUCTURAL DETERMINANTS OF CO STRETCHING VIBRATION FREQUENCIES IN MYOGLOBIN
Descriptor:MYOGLOBIN, SULFATE ION, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Li, T., Phillips Jr., G.N.
Deposit date:1993-10-14
Release date:1994-01-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural determinants of the stretching frequency of CO bound to myoglobin.
Biochemistry, 33, 1994
2B5L
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CRYSTAL STRUCTURE OF DDB1 IN COMPLEX WITH SIMIAN VIRUS 5 V PROTEIN
Descriptor:damage-specific DNA binding protein 1, Nonstructural protein V, ZINC ION
Authors:Li, T., Chen, X., Garbutt, K.C., Zhou, P., Zheng, N.
Deposit date:2005-09-28
Release date:2006-02-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structure of DDB1 in complex with a paramyxovirus V protein: viral hijack of a propeller cluster in ubiquitin ligase.
Cell(Cambridge,Mass.), 124, 2006
2B5M
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CRYSTAL STRUCTURE OF DDB1
Descriptor:damage-specific DNA binding protein 1
Authors:Li, T., Chen, X., Garbutt, K.C., Zhou, P., Zheng, N.
Deposit date:2005-09-28
Release date:2006-02-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.92 Å)
Cite:Structure of DDB1 in complex with a paramyxovirus V protein: viral hijack of a propeller cluster in ubiquitin ligase.
Cell(Cambridge,Mass.), 124, 2006
2B5N
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CRYSTAL STRUCTURE OF THE DDB1 BPB DOMAIN
Descriptor:damage-specific DNA binding protein 1, ISOPROPYL ALCOHOL
Authors:Li, T., Chen, X., Garbutt, K.C., Zhou, P., Zheng, N.
Deposit date:2005-09-28
Release date:2006-02-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of DDB1 in complex with a paramyxovirus V protein: viral hijack of a propeller cluster in ubiquitin ligase.
Cell(Cambridge,Mass.), 124, 2006
3I7H
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CRYSTAL STRUCTURE OF DDB1 IN COMPLEX WITH THE H-BOX MOTIF OF HBX
Descriptor:DNA damage-binding protein 1, X protein
Authors:Li, T., Robert, E.I., Breugel, P.C.V., Strubin, M., Zheng, N.
Deposit date:2009-07-08
Release date:2009-12-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery.
Nat.Struct.Mol.Biol., 17, 2010
3I7K
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CRYSTAL STRUCTURE OF DDB1 IN COMPLEX WITH THE H-BOX MOTIF OF WHX
Descriptor:DNA damage-binding protein 1, X protein
Authors:Li, T., Robert, E.I., Breugel, P.C.V., Strubin, M., Zheng, N.
Deposit date:2009-07-08
Release date:2009-12-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery.
Nat.Struct.Mol.Biol., 17, 2010
3I7L
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CRYSTAL STRUCTURE OF DDB1 IN COMPLEX WITH THE H-BOX MOTIF OF DDB2
Descriptor:DNA damage-binding protein 1, DNA damage-binding protein 2
Authors:Li, T., Robert, E.I., Breugel, P.C.V., Strubin, M., Zheng, N.
Deposit date:2009-07-08
Release date:2009-12-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery.
Nat.Struct.Mol.Biol., 17, 2010
3I7N
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CRYSTAL STRUCTURE OF DDB1 IN COMPLEX WITH THE H-BOX MOTIF OF WDTC1
Descriptor:DNA damage-binding protein 1, WD and tetratricopeptide repeats protein 1
Authors:Li, T., Robert, E.I., Breugel, P.C.V., Strubin, M., Zheng, N.
Deposit date:2009-07-08
Release date:2009-12-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery.
Nat.Struct.Mol.Biol., 17, 2010
3I7O
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CRYSTAL STRUCTURE OF DDB1 IN COMPLEX WITH THE H-BOX MOTIF OF IQWD1
Descriptor:DNA damage-binding protein 1, IQ motif and WD repeat-containing protein 1
Authors:Li, T., Robert, E.I., Breugel, P.C.V., Strubin, M., Zheng, N.
Deposit date:2009-07-08
Release date:2009-12-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery.
Nat.Struct.Mol.Biol., 17, 2010
3I7P
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CRYSTAL STRUCTURE OF DDB1 IN COMPLEX WITH THE H-BOX MOTIF OF WDR40A
Descriptor:DNA damage-binding protein 1, WD repeat-containing protein 40A
Authors:Li, T., Robert, E.I., Breugel, P.C.V., Strubin, M., Zheng, N.
Deposit date:2009-07-08
Release date:2009-12-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery.
Nat.Struct.Mol.Biol., 17, 2010
3I89
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CRYSTAL STRUCTURE OF DDB1 IN COMPLEX WITH THE H-BOX MOTIF OF WDR22
Descriptor:DNA damage-binding protein 1, WD repeat-containing protein 22
Authors:Li, T., Robert, E.I., Breugel, P.C.V., Strubin, M., Zheng, N.
Deposit date:2009-07-09
Release date:2009-12-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery.
Nat.Struct.Mol.Biol., 17, 2010
3I8C
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CRYSTAL STRUCTURE OF DDB1 IN COMPLEX WITH THE H-BOX MOTIF OF WDR21A
Descriptor:DNA damage-binding protein 1, WD repeat-containing protein 21A
Authors:Li, T., Robert, E.I., Breugel, P.C.V., Strubin, M., Zheng, N.
Deposit date:2009-07-09
Release date:2009-12-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery.
Nat.Struct.Mol.Biol., 17, 2010
3I8E
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CRYSTAL STRUCTURE OF DDB1 IN COMPLEX WITH THE H-BOX MOTIF OF WDR42A
Descriptor:DNA damage-binding protein 1, WD repeat-containing protein 42A
Authors:Li, T., Robert, E.I., Breugel, P.C.V., Strubin, M., Zheng, N.
Deposit date:2009-07-09
Release date:2009-12-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery.
Nat.Struct.Mol.Biol., 17, 2010
6CGC
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CRYSTAL STRUCTURE OF HUMAN 17BETA-HSD TYPE 1 IN TERNARY COMPLEX WITH 2-MEO-CC-156 AND NADP+
Descriptor:Estradiol 17-beta-dehydrogenase 1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 3-{[(9beta,14beta,16alpha,17alpha)-3,17-dihydroxy-2-methoxyestra-1,3,5(10)-trien-16-yl]methyl}benzamide
Authors:Li, T., Lin, S.X.
Deposit date:2018-02-19
Release date:2019-01-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Combined Biophysical Chemistry Reveals a New Covalent Inhibitor with a Low-Reactivity Alkyl Halide.
J Phys Chem Lett, 9, 2018
6CGE
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CRYSTAL STRUCTURE OF HUMAN 17BETA-HSD TYPE 1 IN TERNARY COMPLEX WITH PBRM AND NADP+
Descriptor:Estradiol 17-beta-dehydrogenase 1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 3-{[(14beta,16alpha,17alpha)-3-(2-bromoethyl)-17-hydroxyestra-1,3,5(10)-trien-16-yl]methyl}benzamide
Authors:Li, T., Lin, S.X.
Deposit date:2018-02-20
Release date:2019-01-16
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Combined Biophysical Chemistry Reveals a New Covalent Inhibitor with a Low-Reactivity Alkyl Halide.
J Phys Chem Lett, 9, 2018
6DTP
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CRYSTAL STRUCTURE OF HUMAN 17BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 COMPLEXED WITH EM139
Descriptor:Estradiol 17-beta-dehydrogenase 1, GLYCEROL, 1,2-ETHANEDIOL, ...
Authors:Li, T., Lin, S.X.
Deposit date:2018-06-18
Release date:2018-09-12
Method:X-RAY DIFFRACTION (2 Å)
Cite:CRYSTAL STRUCTURE OF HUMAN 17BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 COMPLEXED WITH Dual-Site Inhibitor EM-139
Health, 2018
6MNC
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CRYSTAL STRUCTURE OF HUMAN 17BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 COMPLEXED WITH ESTRONE
Descriptor:Estradiol 17-beta-dehydrogenase 1, DI(HYDROXYETHYL)ETHER, (9beta,13alpha)-3-hydroxyestra-1,3,5(10)-trien-17-one
Authors:Li, T., Stephen, P., Zhu, D.W., Lin, S.X.
Deposit date:2018-10-01
Release date:2019-04-03
Last modified:2019-06-12
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structures of human 17 beta-hydroxysteroid dehydrogenase type 1 complexed with estrone and NADP+reveal the mechanism of substrate inhibition.
Febs J., 286, 2019
6MNE
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CRYSTAL STRUCTURE OF HUMAN 17BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 COMPLEXED WITH ESTRONE AND NADP+
Descriptor:Estradiol 17-beta-dehydrogenase 1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, (9beta,13alpha)-3-hydroxyestra-1,3,5(10)-trien-17-one, ...
Authors:Li, T., Lin, S.X.
Deposit date:2018-10-01
Release date:2019-04-03
Last modified:2019-06-12
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Crystal structures of human 17 beta-hydroxysteroid dehydrogenase type 1 complexed with estrone and NADP+reveal the mechanism of substrate inhibition.
Febs J., 286, 2019
1LTW
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RECOMBINANT SPERM WHALE MYOGLOBIN 29W MUTANT (OXY)
Descriptor:MYOGLOBIN, SULFATE ION, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Li, T., Olson, J.S., Phillips Jr., G.N.
Deposit date:1996-11-02
Release date:1996-12-23
Last modified:2018-03-28
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Perturbation of the Fe-O2 Bond by Nearby Residues in Heme Pocket: Observation of Vfe-O2 Raman Bands for Oxymyoglobin Mutants
J.Am.Chem.Soc., 118, 1996
1MCY
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SPERM WHALE MYOGLOBIN (MUTANT WITH INITIATOR MET AND WITH HIS 64 REPLACED BY GLN, LEU 29 REPLACED BY PHE
Descriptor:MYOGLOBIN (CARBONMONOXY), SULFATE ION, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Li, T., Phillips Jr., G.N.
Deposit date:1995-07-19
Release date:1995-12-07
Last modified:2012-02-22
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:A double mutant of sperm whale myoglobin mimics the structure and function of elephant myoglobin.
J.Biol.Chem., 270, 1995