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3PFT
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CRYSTAL STRUCTURE OF UNTAGGED C54A MUTANT FLAVIN REDUCTASE (DSZD) IN COMPLEX WITH FMN FROM MYCOBACTERIUM GOODII
分子名称:Flavin reductase, FLAVIN MONONUCLEOTIDE
著者Li, Q., Xu, P., Ma, C., Gu, L., Liu, X., Zhang, C., Li, N., Su, J., Li, B., Liu, S.
登録日2010-10-29
公開日2011-11-02
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (1.601 Å)
主引用文献The flavin reductase DSZD from a desulfurizing mycobacterium goodii strain: systemic manipulation and investigation based on the crystal structure
To be Published
2MV6
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SOLUTION STRUCTURE OF THE TRANSMEMBRANE DOMAIN AND THE JUXTA-MEMBRANE DOMAIN OF THE ERYTHROPOIETIN RECEPTOR IN MICELLES
分子名称:Erythropoietin receptor
著者Li, Q., Wong, Y., Huang, Q., Kang, C.
登録日2014-09-23
公開日2014-12-10
実験手法SOLUTION NMR
主引用文献Structural insight into the transmembrane domain and the juxtamembrane region of the erythropoietin receptor in micelles.
Biophys.J., 107, 2014
1X81
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FARNESYL TRANSFERASE STRUCTURE OF JANSEN COMPOUND
分子名称:Protein farnesyltransferase/geranylgeranyltransferase type I alpha subunit, Protein farnesyltransferase beta subunit, ZINC ION, ...
著者Li, Q., Claiborne, A., Li, T., Hasvold, L., Stoll, V.S., Muchmore, S., Jakob, C.G., Gu, W., Cohen, J., Hutchins, C., Frost, D., Rosenberg, S.H., Sham, H.L.
登録日2004-08-16
公開日2004-12-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Design, synthesis, and activity of 4-quinolone and pyridone compounds as nonthiol-containing farnesyltransferase inhibitors.
Bioorg.Med.Chem.Lett., 14, 2004
2F7X
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PROTEIN KINASE A BOUND TO (S)-2-(1H-INDOL-3-YL)-1-[5-((E)-2-PYRIDIN-4-YL-VINYL)-PYRIDIN-3-YLOXYMETHYL]-ETHYLAMINE
分子名称:cAMP-dependent protein kinase, alpha-catalytic subunit, PKI, ...
著者Li, Q., Li, T., Zhu, G.D., Gong, J., Claibone, A., Dalton, C., Luo, Y., Johnson, E.F., Shi, Y., Liu, X., Klinghofer, V., Bauch, J.L., Marsh, K.C., Bouska, J.J., Arries, S., De Jong, R., Oltersdorf, T., Stoll, V.S., Jakob, C.G., Rosenberg, S.H., Giranda, V.L.
登録日2005-12-01
公開日2006-06-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Discovery of trans-3,4'-bispyridinylethylenes as potent and novel inhibitors of protein kinase B (PKB/Akt) for the treatment of cancer: Synthesis and biological evaluation.
Bioorg.Med.Chem.Lett., 16, 2006
2F7Z
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PROTEIN KINASE A BOUND TO (R)-1-(1H-INDOL-3-YLMETHYL)-2-(2-PYRIDIN-4-YL-[1,7]NAPHTYRIDIN-5-YLOXY)-EHYLAMINE
分子名称:cAMP-dependent protein kinase, alpha-catalytic subunit, PKI, ...
著者Li, Q., Woods, K.W., Thomas, S., Zhu, G.D., Packard, G., Fisher, J., Li, T., Gong, J., Dinges, J., Song, X., Abrams, J., Luo, Y., Johnson, E.F., Shi, Y., Liu, X., Klinghofer, V., Des Jong, R., Oltersdorf, T., Stoll, V.S., Jakob, C.G., Rosenberg, S.H., Giranda, V.L.
登録日2005-12-01
公開日2006-06-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Synthesis and structure-activity relationship of 3,4'-bispyridinylethylenes: discovery of a potent 3-isoquinolinylpyridine inhibitor of protein kinase B (PKB/Akt) for the treatment of cancer.
Bioorg.Med.Chem.Lett., 16, 2006
4FVK
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STRUCTURAL AND FUNCTIONAL CHARACTERIZATION OF NEURAMINIDASE-LIKE MOLECULE N10 DERIVED FROM BAT INFLUENZA A VIRUS
分子名称:Neuraminidase, CALCIUM ION, ZINC ION, ...
著者Li, Q., Sun, X.M., Li, Z.X., Liu, Y., Vavricka, C.J., Qi, J.X., Gao, G.F.
登録日2012-06-29
公開日2012-09-19
最終更新日2013-07-03
実験手法X-RAY DIFFRACTION (2.198 Å)
主引用文献Structural and functional characterization of neuraminidase-like molecule N10 derived from bat influenza A virus
Proc.Natl.Acad.Sci.USA, 109, 2012
4ZHS
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CRYSTAL STRUCTURE OF ASPARTATE SEMIALDEHYDE DEHYDROGENASE FROM TRICHOPHYTON RUBRUM
分子名称:Aspartate Semialdehyde Dehydrogenase, SULFATE ION
著者Li, Q., Cui, S.
登録日2015-04-27
公開日2016-03-02
実験手法X-RAY DIFFRACTION (2.603 Å)
主引用文献Structural Insights into the Tetrameric State of Aspartate-beta-semialdehyde Dehydrogenases from Fungal Species
Sci Rep, 6, 2016
4ZIC
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CRYSTAL STRUCTURE OF ASPARTATE SEMIALDEHYDE DEHYDROGENASE WITH NADP FROM TRICHOPHYTON RUBRUM
分子名称:Aspartate Semialdehyde Dehydrogenase, SULFATE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Li, Q., Cui, S.
登録日2015-04-28
公開日2016-03-02
実験手法X-RAY DIFFRACTION (2.553 Å)
主引用文献Structural Insights into the Tetrameric State of Aspartate-beta-semialdehyde Dehydrogenases from Fungal Species
Sci Rep, 6, 2016
2MXB
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STRUCTURE OF THE TRANSMEMBRANE DOMAIN OF THE MOUSE ERYTHROPOIETIN RECEPTOR
分子名称:Erythropoietin receptor
著者Li, Q., Wong, Y., Lee, M., Kang, C.
登録日2014-12-19
公開日2015-09-23
実験手法SOLUTION NMR
主引用文献Solution structure of the transmembrane domain of the mouse erythropoietin receptor in detergent micelles.
Sci Rep, 5, 2015
3NSS
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THE 2009 PANDEMIC H1N1 NEURAMINIDASE N1 LACKS THE 150-CAVITY IN ITS ACTIVE SITES
分子名称:Neuraminidase, N-ACETYL-D-GLUCOSAMINE, ALPHA-D-MANNOSE, ...
著者Li, Q., Qi, J.X., Zhang, W., Vavricka, C.J., Shi, Y., Gao, G.F.
登録日2010-07-02
公開日2010-09-22
最終更新日2014-02-26
実験手法X-RAY DIFFRACTION (1.902 Å)
主引用文献The 2009 pandemic H1N1 neuraminidase N1 lacks the 150-cavity in its active site
Nat.Struct.Mol.Biol., 17, 2010
4OE1
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CRYSTAL STRUCTURE OF THE PENTATRICOPEPTIDE REPEAT PROTEIN PPR10 (C256S/C430S/C449S) IN COMPLEX WITH AN 18-NT PSAJ RNA ELEMENT
分子名称:Chloroplast pentatricopeptide repeat protein 10, psaJ RNA, PHOSPHATE ION
著者Li, Q., Yan, C., Wu, J., Yin, P., Yan, N.
登録日2014-01-11
公開日2014-09-24
最終更新日2015-02-18
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Examination of the dimerization states of the single-stranded RNA recognition protein pentatricopeptide repeat 10 (PPR10).
J.Biol.Chem., 289, 2014
4RFR
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COMPLEX STRUCTURE OF ALKB/RHEIN
分子名称:Alpha-ketoglutarate-dependent dioxygenase AlkB, 4,5-dihydroxy-9,10-dioxo-9,10-dihydroanthracene-2-carboxylic acid, MANGANESE (II) ION
著者Li, Q., Huang, Y., Li, J.F., Yang, C.-G.
登録日2014-09-27
公開日2016-04-06
最終更新日2016-09-28
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Rhein Inhibits AlkB Repair Enzymes and Sensitizes Cells to Methylated DNA Damage.
J.Biol.Chem., 291, 2016
1OR5
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SOLUTION STRUCTURE OF THE HOLO-FORM OF THE FRENOLICIN ACYL CARRIER PROTEIN, MINIMIZED MEAN STRUCTURE
分子名称:acyl carrier protein
著者Li, Q., Khosla, C., Puglisi, J., Liu, C.W.
登録日2003-03-11
公開日2003-07-01
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Solution Structure and Backbone Dynamics of the Holo Form of the Frenolicin Acyl Carrier Protein
Biochemistry, 42, 2003
1ZCM
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HUMAN CALPAIN PROTEASE CORE INHIBITED BY ZLLYCH2F
分子名称:Calpain 1, large [catalytic] subunit, CALCIUM ION, ...
著者Li, Q., Hanzlik, R.P., Weaver, R.F., Schonbrunn, E.
登録日2005-04-12
公開日2006-01-31
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Molecular mode of action of a covalently inhibiting peptidomimetic on the human calpain protease core
Biochemistry, 45, 2006
2I1J
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MOESIN FROM SPODOPTERA FRUGIPERDA AT 2.1 ANGSTROMS RESOLUTION
分子名称:Moesin, CHLORIDE ION, UREA, ...
著者Li, Q., Nance, M.R., Tesmer, J.J.G.
登録日2006-08-14
公開日2006-12-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Self-masking in an Intact ERM-merlin Protein: An Active Role for the Central alpha-Helical Domain.
J.Mol.Biol., 365, 2007
2MFR
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SOLUTION STRUCTURE OF THE TRANSMEMBRANE DOMAIN OF THE INSULIN RECEPTOR IN MICELLES
分子名称:Insulin receptor
著者Li, Q., Wong, Y.L., Kang, C.
登録日2013-10-20
公開日2014-04-02
実験手法SOLUTION NMR
主引用文献Solution structure of the transmembrane domain of the insulin receptor in detergent micelles
Biochim.Biophys.Acta, 1838, 2014
2MHF
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SOLUTION STRUCTURE OF THE CYCLIC-NUCLEOTIDE BINDING HOMOLOGY DOMAIN OF A KCNH CHANNEL
分子名称:Uncharacterized protein
著者Li, Q., Ng, H.
登録日2013-11-21
公開日2014-04-02
実験手法SOLUTION NMR
主引用文献Solution structure of the cyclic-nucleotide binding homology domain of a KCNH channel
J.Struct.Biol., 2014
4G7V
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CRYSTAL STRUCTURE OF VOLTAGE SENSING DOMAIN OF CI-VSP WITH FRAGMENT ANTIBODY (R217E, 2.5 A)
分子名称:fragment antibody heavy chain, fragment antibody light chain, Voltage-sensor containing phosphatase, ...
著者Li, Q.
登録日2012-07-20
公開日2014-02-05
最終更新日2017-12-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural mechanism of voltage-dependent gating in an isolated voltage-sensing domain.
Nat. Struct. Mol. Biol., 21, 2014
4G7Y
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CRYSTAL STRUCTURE OF VOLTAGE SENSING DOMAIN OF CI-VSP WITH FRAGMENT ANTIBODY (R217E, 2.8 A)
分子名称:Fragment antibody heavy chain, Fragment antibody light chain, Voltage-sensor containing phosphatase, ...
著者Li, Q.
登録日2012-07-20
公開日2014-02-05
最終更新日2019-07-17
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural mechanism of voltage-dependent gating in an isolated voltage-sensing domain.
Nat. Struct. Mol. Biol., 21, 2014
4G80
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CRYSTAL STRUCTURE OF VOLTAGE SENSING DOMAIN OF CI-VSP WITH FRAGMENT ANTIBODY (WT, 3.8 A)
分子名称:Voltage-sensor containing phosphatase, fragment antibody heavy chain, fragment antibody light chain
著者Li, Q.
登録日2012-07-20
公開日2014-02-05
最終更新日2017-12-13
実験手法X-RAY DIFFRACTION (3.58 Å)
主引用文献Structural mechanism of voltage-dependent gating in an isolated voltage-sensing domain.
Nat. Struct. Mol. Biol., 21, 2014
4HZV
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THE CRYSTAL STRUCTURE OF INFLUENZA A NEURAMINIDASE N3
分子名称:Neuraminidase, N-ACETYL-D-GLUCOSAMINE, ALPHA-L-FUCOSE, ...
著者Li, Q., Qi, J., Vavricka, C.J., Gao, G.F.
登録日2012-11-15
公開日2013-11-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Functional and structural analysis of influenza virus neuraminidase N3 offers further insight into the mechanisms of oseltamivir resistance.
J.Virol., 87, 2013
4HZW
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CRYSTAL STRUCTURE OF INFLUENZA A NEURAMINIDASE N3 COMPLEXED WITH LANINAMIVIR
分子名称:Neuraminidase, N-ACETYL-D-GLUCOSAMINE, ALPHA-L-FUCOSE, ...
著者Li, Q., Qi, J., Vavricka, C.J., Gao, G.F.
登録日2012-11-15
公開日2013-11-06
実験手法X-RAY DIFFRACTION (1.701 Å)
主引用文献Functional and structural analysis of influenza virus neuraminidase N3 offers further insight into the mechanisms of oseltamivir resistance.
J.Virol., 87, 2013
4HZX
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CRYSTAL STRUCTURE OF INFLUENZA A NEURAMINIDASE N3 COMPLEXED WITH OSELTAMIVIR
分子名称:Neuraminidase, N-ACETYL-D-GLUCOSAMINE, ALPHA-L-FUCOSE, ...
著者Li, Q., Qi, J., Vavricka, C.J., Gao, G.F.
登録日2012-11-15
公開日2013-11-06
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Functional and structural analysis of influenza virus neuraminidase N3 offers further insight into the mechanisms of oseltamivir resistance.
J.Virol., 87, 2013
4HZY
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CRYSTAL STRUCTURE OF INFLUENZA A NEURAMINIDASE N3-H274Y
分子名称:Neuraminidase, N-ACETYL-D-GLUCOSAMINE, ALPHA-L-FUCOSE, ...
著者Li, Q., Qi, J., Vavricka, C.J., Gao, G.F.
登録日2012-11-16
公開日2013-11-06
実験手法X-RAY DIFFRACTION (1.598 Å)
主引用文献Functional and structural analysis of influenza virus neuraminidase N3 offers further insight into the mechanisms of oseltamivir resistance.
J.Virol., 87, 2013
4HZZ
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CRYSTAL STRUCTURE OF INFLUENZA NEURAMINIDASE N3-H274Y COMPLEXED WITH OSELTAMIVIR
分子名称:Neuraminidase, N-ACETYL-D-GLUCOSAMINE, ALPHA-L-FUCOSE, ...
著者Li, Q., Qi, J., Vavricka, C.J., Gao, G.F.
登録日2012-11-16
公開日2013-11-06
実験手法X-RAY DIFFRACTION (1.601 Å)
主引用文献Functional and structural analysis of influenza virus neuraminidase N3 offers further insight into the mechanisms of oseltamivir resistance.
J.Virol., 87, 2013