1JWT
| CRYSTAL STRUCTURE OF THROMBIN IN COMPLEX WITH A NOVEL BICYCLIC LACTAM INHIBITOR | Descriptor: | 4-OXO-2-PHENYLMETHANESULFONYL-OCTAHYDRO-PYRROLO[1,2-A]PYRAZINE-6-CARBOXYLIC ACID [1-(N-HYDROXYCARBAMIMIDOYL)-PIPERIDIN-4-YLMETHYL]-AMIDE, Prothrombin | Authors: | Levesque, S, St-Denis, Y, Bachand, B, Preville, P, Leblond, L, Winocour, P.D, Edmunds, J.J, Rubin, J.R, Siddiqui, M.A. | Deposit date: | 2001-09-05 | Release date: | 2002-02-27 | Last modified: | 2017-10-04 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Novel bicyclic lactam inhibitors of thrombin: potency and selectivity optimization through P1 residues. Bioorg.Med.Chem.Lett., 11, 2001
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6RJD
| Cryo-EM structure of St1Cas9-sgRNA-tDNA59-ntPAM complex. | Descriptor: | Streptococcus Thermophilus 1 Cas9, ntPAM, sgRNA (78-MER), ... | Authors: | Goulet, A, Chaves-Sanjuan, A, Cambillau, C. | Deposit date: | 2019-04-26 | Release date: | 2019-10-02 | Last modified: | 2020-01-01 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Cas9 Allosteric Inhibition by the Anti-CRISPR Protein AcrIIA6. Mol.Cell, 76, 2019
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6RJ9
| Cryo-EM structure of St1Cas9-sgRNA-tDNA20-AcrIIA6 monomeric assembly. | Descriptor: | AcrIIA6, CRISPR-associated endonuclease Cas9 1, sgRNA, ... | Authors: | Goulet, A, Chaves-Sanjuan, A, Cambillau, C. | Deposit date: | 2019-04-26 | Release date: | 2019-10-02 | Last modified: | 2021-06-30 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Cas9 Allosteric Inhibition by the Anti-CRISPR Protein AcrIIA6. Mol.Cell, 76, 2019
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6RJA
| Cryo-EM structure of St1Cas9-sgRNA-tDNA20-AcrIIA6 dimeric assembly. | Descriptor: | AcrIIA6, CRISPR-associated endonuclease Cas9 1, RNA (78-MER), ... | Authors: | Goulet, A, Cambillau, C, Chaves-Sanjuan, A. | Deposit date: | 2019-04-26 | Release date: | 2019-10-02 | Last modified: | 2021-06-30 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Cas9 Allosteric Inhibition by the Anti-CRISPR Protein AcrIIA6. Mol.Cell, 76, 2019
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6RJG
| Cryo-EM structure of St1Cas9-sgRNA-AcrIIA6-tDNA59-ntPAM complex. | Descriptor: | AcrIIA6, Cas 9, ntPAM, ... | Authors: | Goulet, A, Chaves-Sanjuan, A, Cambillau, C. | Deposit date: | 2019-04-26 | Release date: | 2019-10-02 | Last modified: | 2020-01-01 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Cas9 Allosteric Inhibition by the Anti-CRISPR Protein AcrIIA6. Mol.Cell, 76, 2019
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