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1J7N
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BU of 1j7n by Molmil
Anthrax Toxin Lethal factor
Descriptor: Lethal Factor precursor, SULFATE ION, ZINC ION
Authors:Pannifer, A.D, Wong, T.Y, Schwarzenbacher, R, Renatus, M, Petosa, C, Collier, R.J, Bienkowska, J, Lacy, D.B, Park, S, Leppla, S.H, Hanna, P, Liddington, R.C.
Deposit date:2001-05-17
Release date:2001-11-07
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the anthrax lethal factor.
Nature, 414, 2001
1JKY
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BU of 1jky by Molmil
Crystal Structure of the Anthrax Lethal Factor (LF): Wild-type LF Complexed with the N-terminal Sequence of MAPKK2
Descriptor: Lethal Factor, mitogen-activated protein kinase kinase 2
Authors:Pannifer, A.D, Wong, T.Y, Schwarzenbacher, R, Renatus, M, Petosa, C, Collier, R.J, Bienkowska, J, Lacy, D.B, Park, S, Leppla, S.H, Hanna, P, Liddington, R.C.
Deposit date:2001-07-13
Release date:2001-11-07
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Crystal structure of the anthrax lethal factor.
Nature, 414, 2001
1T6B
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BU of 1t6b by Molmil
Crystal structure of B. anthracis Protective Antigen complexed with human Anthrax toxin receptor
Descriptor: Anthrax toxin receptor 2, CALCIUM ION, MANGANESE (II) ION, ...
Authors:Santelli, E, Bankston, L.A, Leppla, S.H, Liddington, R.C.
Deposit date:2004-05-05
Release date:2004-07-20
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of a complex between anthrax toxin and its host cell receptor
Nature, 430, 2004
1ACC
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BU of 1acc by Molmil
ANTHRAX PROTECTIVE ANTIGEN
Descriptor: ANTHRAX PROTECTIVE ANTIGEN, CALCIUM ION
Authors:Petosa, C, Liddington, R.C.
Deposit date:1997-02-05
Release date:1998-02-11
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of the anthrax toxin protective antigen.
Nature, 385, 1997
7TQB
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BU of 7tqb by Molmil
Crystal structure of monoclonal S9.6 Fab bound to DNA-RNA hybrid
Descriptor: DNA, FAB S9.6 Heavy Chain, FAB S9.6 Light Chain, ...
Authors:Bou-Nader, C, Zhang, J.
Deposit date:2022-01-26
Release date:2022-03-30
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural basis of R-loop recognition by the S9.6 monoclonal antibody.
Nat Commun, 13, 2022
7TQA
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BU of 7tqa by Molmil
Crystal Structure of monoclonal S9.6 Fab
Descriptor: Fab S9.6 heavy chain, Fab S9.6 light chain, GLYCEROL, ...
Authors:Bou-Nader, C, Zhang, J.
Deposit date:2022-01-26
Release date:2022-03-30
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.328 Å)
Cite:Structural basis of R-loop recognition by the S9.6 monoclonal antibody.
Nat Commun, 13, 2022
7NMQ
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BU of 7nmq by Molmil
Bacillus cereus HblL1 toxin component
Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Hemolysin BL lytic component L1
Authors:Rizkallah, P.J, Berry, C.
Deposit date:2021-02-23
Release date:2021-04-07
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.36 Å)
Cite:The Crystal Structure of Bacillus cereus HblL 1 .
Toxins, 13, 2021
4DV8
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BU of 4dv8 by Molmil
Anthrax Lethal Factor metalloproteinase in complex with the Hydroxamic acid based small molecule PT8421
Descriptor: (2S)-6-[(4-fluorobenzyl)amino]-2-[(2R)-2-(4-fluorophenyl)-2-methoxyethyl]-N-hydroxyhexanamide, Lethal factor, MALONATE ION, ...
Authors:Margosiak, S.A, Sankaran, B.
Deposit date:2012-02-22
Release date:2012-03-14
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.632 Å)
Cite:Antidotes to anthrax lethal factor intoxication. Part 3: Evaluation of core structures and further modifications to the C2-side chain.
Bioorg.Med.Chem.Lett., 22, 2012
4YU5
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BU of 4yu5 by Molmil
Crystal structure of selenomethionine variant of Bacillus anthracis immune inhibitor A2 peptidase zymogen
Descriptor: 3-(1-methylpiperidinium-1-yl)propane-1-sulfonate, CALCIUM ION, GLYCEROL, ...
Authors:Arolas, J.L, Goulas, T, Gomis-Ruth, F.X.
Deposit date:2015-03-18
Release date:2015-10-28
Last modified:2016-01-20
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural Basis for Latency and Function of Immune Inhibitor A Metallopeptidase, a Modulator of the Bacillus anthracis Secretome.
Structure, 24, 2016
4YU6
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BU of 4yu6 by Molmil
Crystal structure of Bacillus anthracis immune inhibitor A2 peptidase zymogen
Descriptor: ACETONITRILE, CALCIUM ION, Immune inhibitor A, ...
Authors:Arolas, J.L, Goulas, T, Gomis-Ruth, F.X.
Deposit date:2015-03-18
Release date:2015-10-28
Last modified:2016-01-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Basis for Latency and Function of Immune Inhibitor A Metallopeptidase, a Modulator of the Bacillus anthracis Secretome.
Structure, 24, 2016
1PWQ
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BU of 1pwq by Molmil
Crystal structure of Anthrax Lethal Factor complexed with Thioacetyl-Tyr-Pro-Met-Amide, a metal-chelating peptidyl small molecule inhibitor
Descriptor: Lethal factor, N-(SULFANYLACETYL)TYROSYLPROLYLMETHIONINAMIDE, ZINC ION
Authors:Wong, T.Y, Schwarzenbacher, R, Liddington, R.C.
Deposit date:2003-07-02
Release date:2004-01-13
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3.52 Å)
Cite:The structural basis for substrate and inhibitor selectivity of the anthrax lethal factor.
Nat.Struct.Mol.Biol., 11, 2004
1PWW
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BU of 1pww by Molmil
Crystal structure of Anthrax Lethal Factor active site mutant protein complexed with an optimised peptide substrate in the presence of zinc.
Descriptor: LF20, Lethal factor, ZINC ION
Authors:Wong, T.Y, Schwarzenbacher, R, Liddington, R.C.
Deposit date:2003-07-02
Release date:2004-01-27
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The structural basis for substrate and inhibitor selectivity of the anthrax lethal factor.
Nat.Struct.Mol.Biol., 11, 2004
1PWV
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BU of 1pwv by Molmil
Crystal structure of Anthrax Lethal Factor wild-type protein complexed with an optimised peptide substrate.
Descriptor: LF20, Lethal factor
Authors:Wong, T.Y, Schwarzenbacher, R, Liddington, R.C.
Deposit date:2003-07-02
Release date:2004-02-03
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:The structural basis for substrate and inhibitor selectivity of the anthrax lethal factor.
Nat.Struct.Mol.Biol., 11, 2004
1PWU
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BU of 1pwu by Molmil
Crystal Structure of Anthrax Lethal Factor complexed with (3-(N-hydroxycarboxamido)-2-isobutylpropanoyl-Trp-methylamide), a known small molecule inhibitor of matrix metalloproteases.
Descriptor: 3-(N-HYDROXYCARBOXAMIDO)-2-ISOBUTYLPROPANOYL-TRP-METHYLAMIDE, Lethal factor, ZINC ION
Authors:Wong, T.Y, Schwarzenbacher, R, Liddington, R.C.
Deposit date:2003-07-02
Release date:2004-02-03
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The structural basis for substrate and inhibitor selectivity of the anthrax lethal factor.
Nat.Struct.Mol.Biol., 11, 2004

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