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2GAQ
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BU of 2gaq by Molmil
NMR SOLUTION STRUCTURE OF THE FRB DOMAIN OF mTOR
Descriptor: FKBP12-rapamycin complex-associated protein
Authors:Leone, M, Pellecchia, M.
Deposit date:2006-03-09
Release date:2006-08-08
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:The FRB Domain of mTOR: NMR Solution Structure and Inhibitor Design.
Biochemistry, 45, 2006
1RQM
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BU of 1rqm by Molmil
SOLUTION STRUCTURE OF THE K18G/R82E ALICYCLOBACILLUS ACIDOCALDARIUS THIOREDOXIN MUTANT
Descriptor: Thioredoxin
Authors:Leone, M, Di Lello, P, Ohlenschlager, O, Pedone, E.M, Bartolucci, S, Rossi, M, Di Blasio, B, Pedone, C, Saviano, M, Isernia, C, Fattorusso, R.
Deposit date:2003-12-05
Release date:2004-06-22
Last modified:2021-10-27
Method:SOLUTION NMR
Cite:Solution Structure and Backbone Dynamics of the K18G/R82E Alicyclobacillus acidocaldarius Thioredoxin Mutant: A Molecular Analysis of Its Reduced Thermal Stability.
Biochemistry, 43, 2004
2GJY
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BU of 2gjy by Molmil
NMR Solution Structure of Tensin1 PTB Domain
Descriptor: Tensin
Authors:Leone, M, Pellecchia, M.
Deposit date:2006-03-31
Release date:2007-04-03
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:The PTB domain of tensin: NMR solution structure and phosphoinositides binding studies.
Biopolymers, 89, 2007
2KG5
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BU of 2kg5 by Molmil
NMR Solution structure of ARAP3-SAM
Descriptor: Arf-GAP, Rho-GAP domain, ANK repeat and PH domain-containing protein 3
Authors:Leone, M, Pellecchia, M.
Deposit date:2009-03-05
Release date:2009-11-17
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:The Sam domain of the lipid phosphatase Ship2 adopts a common model to interact with Arap3-Sam and EphA2-Sam.
Bmc Struct.Biol., 9, 2009
2K4P
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BU of 2k4p by Molmil
Solution Structure of Ship2-Sam
Descriptor: Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2
Authors:Leone, M, Pellecchia, M.
Deposit date:2008-06-16
Release date:2008-11-25
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:NMR Studies of a Heterotypic Sam-Sam Domain Association: The Interaction between the Lipid Phosphatase Ship2 and the EphA2 Receptor.
Biochemistry, 47, 2008
2LMR
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BU of 2lmr by Molmil
Solution structure of the first sam domain of odin
Descriptor: Ankyrin repeat and SAM domain-containing protein 1A
Authors:Leone, M, Mercurio, F.
Deposit date:2011-12-12
Release date:2012-03-14
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Solution Structure of the First Sam Domain of Odin and Binding Studies with the EphA2 Receptor.
Biochemistry, 51, 2012
6F7O
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BU of 6f7o by Molmil
NMR structure of an Odin-Sam1 stapled peptide
Descriptor: Ankyrin repeat and SAM domain-containing protein 1A
Authors:Leone, M, Mercurio, F.A.
Deposit date:2017-12-11
Release date:2018-08-01
Last modified:2023-11-15
Method:SOLUTION NMR
Cite:Sam domain-based stapled peptides: Structural analysis and interaction studies with the Sam domains from the EphA2 receptor and the lipid phosphatase Ship2.
Bioorg. Chem., 80, 2018
1NJQ
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BU of 1njq by Molmil
NMR structure of the single QALGGH zinc finger domain from Arabidopsis thaliana SUPERMAN protein
Descriptor: ZINC ION, superman protein
Authors:Isernia, C, Bucci, E, Leone, M, Zaccaro, L, Di Lello, P, Digilio, G, Esposito, S, Saviano, M, Di Blasio, B, Pedone, C, Pedone, P.V, Fattorusso, R.
Deposit date:2003-01-02
Release date:2003-03-04
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:NMR Structure of the Single QALGGH Zinc Finger Domain from the Arabidopsis thaliana SUPERMAN Protein.
Chembiochem, 4, 2003
2MYQ
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BU of 2myq by Molmil
NMR structure of an Odin-Sam1 fragment
Descriptor: Ankyrin repeat and SAM domain-containing protein 1A
Authors:Mercurio, F.A, Leone, M.
Deposit date:2015-01-30
Release date:2015-07-08
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Peptide Fragments of Odin-Sam1: Conformational Analysis and Interaction Studies with EphA2-Sam.
Chembiochem, 16, 2015
2A25
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BU of 2a25 by Molmil
Crystal structure of Siah1 SBD bound to the peptide EKPAAVVAPITTG from SIP
Descriptor: Calcyclin-binding protein peptide, Ubiquitin ligase SIAH1, ZINC ION
Authors:Santelli, E, Leone, M, Li, C, Fukushima, T, Preece, N.E, Olson, A.J, Ely, K.R, Reed, J.C, Pellecchia, M, Liddington, R.C, Matsuzawa, S.
Deposit date:2005-06-21
Release date:2005-08-09
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Analysis of Siah1-Siah-interacting Protein Interactions and Insights into the Assembly of an E3 Ligase Multiprotein Complex
J.Biol.Chem., 280, 2005
2A26
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BU of 2a26 by Molmil
Crystal structure of the N-terminal, dimerization domain of Siah Interacting Protein
Descriptor: 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, Calcyclin-binding protein, SULFATE ION
Authors:Santelli, E, Leone, M, Li, C, Fukushima, T, Preece, N.E, Olson, A.J, Ely, K.R, Reed, J.C, Pellecchia, M, Liddington, R.C, Matsuzawa, S.
Deposit date:2005-06-21
Release date:2005-08-09
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Structural Analysis of Siah1-Siah-interacting Protein Interactions and Insights into the Assembly of an E3 Ligase Multiprotein Complex
J.Biol.Chem., 280, 2005
5NZ9
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BU of 5nz9 by Molmil
NMR structure of an EphA2-Sam fragment
Descriptor: Ephrin type-A receptor 2
Authors:Mercurio, F.A, Leone, M.
Deposit date:2017-05-12
Release date:2017-12-20
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:The Sam-Sam interaction between Ship2 and the EphA2 receptor: design and analysis of peptide inhibitors.
Sci Rep, 7, 2017
6F7M
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BU of 6f7m by Molmil
NMR structure of EphA2-Sam stapled peptides (S13ST)
Descriptor: Ephrin type-A receptor 2
Authors:Mercurio, F.A, Leone, M.
Deposit date:2017-12-11
Release date:2018-08-01
Last modified:2023-11-15
Method:SOLUTION NMR
Cite:Sam domain-based stapled peptides: Structural analysis and interaction studies with the Sam domains from the EphA2 receptor and the lipid phosphatase Ship2.
Bioorg. Chem., 80, 2018
6F7N
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BU of 6f7n by Molmil
NMR structure of EphA2-Sam stapled peptides (S13STshort)
Descriptor: Ephrin type-A receptor 2
Authors:Mercurio, F.A, Leone, M.
Deposit date:2017-12-11
Release date:2018-08-01
Last modified:2023-11-15
Method:SOLUTION NMR
Cite:Sam domain-based stapled peptides: Structural analysis and interaction studies with the Sam domains from the EphA2 receptor and the lipid phosphatase Ship2.
Bioorg. Chem., 80, 2018
6FS5
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BU of 6fs5 by Molmil
NMR structure of Casocidin-I antimicrobial peptide in 60% TFE
Descriptor: Alpha-S2-casein
Authors:Mercurio, F.A, Leone, M.
Deposit date:2018-02-19
Release date:2018-10-03
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:The antimicrobial peptides casocidins I and II: Solution structural studies in water and different membrane-mimetic environments.
Peptides, 114, 2019
6FS4
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BU of 6fs4 by Molmil
NMR structure of Casocidin-II antimicrobial peptide in 60% TFE
Descriptor: Alpha-S2-casein
Authors:Mercurio, F.A, Leone, M.
Deposit date:2018-02-19
Release date:2018-10-03
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:The antimicrobial peptides casocidins I and II: Solution structural studies in water and different membrane-mimetic environments.
Peptides, 114, 2019
2L1O
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BU of 2l1o by Molmil
Zinc to cadmium replacement in the A. thaliana SUPERMAN Cys2His2 zinc finger induces structural rearrangements of typical DNA base determinant positions
Descriptor: CADMIUM ION, Transcriptional regulator SUPERMAN
Authors:Malgieri, G, Zaccaro, L, Leone, M, Bucci, E, Esposito, S, Baglivo, I, Del Gatto, A, Scandurra, R, Pedone, P.V, Fattorusso, R, Isernia, C.
Deposit date:2010-07-31
Release date:2011-06-08
Last modified:2011-12-21
Method:SOLUTION NMR
Cite:Zinc to cadmium replacement in the A. thaliana SUPERMAN Cys(2) His(2) zinc finger induces structural rearrangements of typical DNA base determinant positions.
Biopolymers, 95, 2011
1UWI
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BU of 1uwi by Molmil
CRYSTAL STRUCTURE OF MUTATED BETA-GLYCOSIDASE FROM SULFOLOBUS SOLFATARICUS, WORKING AT MODERATE TEMPERATURE
Descriptor: BETA-GALACTOSIDASE
Authors:Isorna, P, Polaina, J, Sanz-Aparicio, J.
Deposit date:2004-02-05
Release date:2005-02-09
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Comparative Study and Mutational Analysis of Distinctive Structural Elements of Hyperthermophilic Enzymes.
Protein J., 26, 2007
2EXJ
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BU of 2exj by Molmil
Structure of the family43 beta-Xylosidase D128G mutant from geobacillus stearothermophilus in complex with xylobiose
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GLYCEROL, ...
Authors:Brux, C, Niefind, K, Shallom-Shezifi, D, Shoham, Y, Schomburg, D.
Deposit date:2005-11-08
Release date:2006-04-04
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The Structure of an Inverting GH43 beta-Xylosidase from Geobacillus stearothermophilus with its Substrate Reveals the Role of the Three Catalytic Residues.
J.Mol.Biol., 359, 2006
2EXI
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BU of 2exi by Molmil
Structure of the family43 beta-Xylosidase D15G mutant from geobacillus stearothermophilus
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GLYCEROL, ...
Authors:Brux, C, Niefind, K, Shallom-Shezifi, D, Shoham, Y, Schomburg, D.
Deposit date:2005-11-08
Release date:2006-04-04
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:The Structure of an Inverting GH43 beta-Xylosidase from Geobacillus stearothermophilus with its Substrate Reveals the Role of the Three Catalytic Residues.
J.Mol.Biol., 359, 2006
2EXK
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BU of 2exk by Molmil
Structure of the family43 beta-Xylosidase E187G from geobacillus stearothermophilus in complex with xylobiose
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GLYCEROL, ...
Authors:Brux, C, Niefind, K, Shallom-Shezifi, D, Shoham, Y, Schomburg, D.
Deposit date:2005-11-08
Release date:2006-04-04
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The Structure of an Inverting GH43 beta-Xylosidase from Geobacillus stearothermophilus with its Substrate Reveals the Role of the Three Catalytic Residues.
J.Mol.Biol., 359, 2006
2EXH
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BU of 2exh by Molmil
Structure of the family43 beta-Xylosidase from geobacillus stearothermophilus
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GLYCEROL, ...
Authors:Brux, C, Niefind, K, Shallom-Shezifi, D, Yuval, S, Schomburg, D.
Deposit date:2005-11-08
Release date:2006-04-04
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:The Structure of an Inverting GH43 beta-Xylosidase from Geobacillus stearothermophilus with its Substrate Reveals the Role of the Three Catalytic Residues.
J.Mol.Biol., 359, 2006
5NHU
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BU of 5nhu by Molmil
HUMAN ALPHA THROMBIN COMPLEXED WITH ANOPHELES GAMBIAE cE5 ANTICOAGULANT
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, AGAP008004-PA, Prothrombin, ...
Authors:Ripoll-Rozada, J, Pereira, P.J.B.
Deposit date:2017-03-22
Release date:2017-06-14
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Functional analyses yield detailed insight into the mechanism of thrombin inhibition by the antihemostatic salivary protein cE5 from Anopheles gambiae.
J. Biol. Chem., 292, 2017

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