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1RQM
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SOLUTION STRUCTURE OF THE K18G/R82E ALICYCLOBACILLUS ACIDOCALDARIUS THIOREDOXIN MUTANT
Descriptor:Thioredoxin
Authors:Leone, M., Di Lello, P., Ohlenschlager, O., Pedone, E.M., Bartolucci, S., Rossi, M., Di Blasio, B., Pedone, C., Saviano, M., Isernia, C., Fattorusso, R.
Deposit date:2003-12-05
Release date:2004-06-22
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution Structure and Backbone Dynamics of the K18G/R82E Alicyclobacillus acidocaldarius Thioredoxin Mutant: A Molecular Analysis of Its Reduced Thermal Stability.
Biochemistry, 43, 2004
2GAQ
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NMR SOLUTION STRUCTURE OF THE FRB DOMAIN OF MTOR
Descriptor:FKBP12-rapamycin complex-associated protein
Authors:Leone, M., Pellecchia, M.
Deposit date:2006-03-09
Release date:2006-08-08
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The FRB Domain of mTOR: NMR Solution Structure and Inhibitor Design.
Biochemistry, 45, 2006
2GJY
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NMR SOLUTION STRUCTURE OF TENSIN1 PTB DOMAIN
Descriptor:Tensin
Authors:Leone, M., Pellecchia, M.
Deposit date:2006-03-31
Release date:2007-04-03
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The PTB domain of tensin: NMR solution structure and phosphoinositides binding studies.
Biopolymers, 89, 2007
2K4P
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SOLUTION STRUCTURE OF SHIP2-SAM
Descriptor:Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2
Authors:Leone, M., Pellecchia, M.
Deposit date:2008-06-16
Release date:2008-11-25
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:NMR Studies of a Heterotypic Sam-Sam Domain Association: The Interaction between the Lipid Phosphatase Ship2 and the EphA2 Receptor.
Biochemistry, 47, 2008
2KG5
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NMR SOLUTION STRUCTURE OF ARAP3-SAM
Descriptor:Arf-GAP, Rho-GAP domain, ANK repeat and PH domain-containing protein 3
Authors:Leone, M., Pellecchia, M.
Deposit date:2009-03-05
Release date:2009-11-17
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The Sam domain of the lipid phosphatase Ship2 adopts a common model to interact with Arap3-Sam and EphA2-Sam.
Bmc Struct.Biol., 9, 2009
2LMR
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SOLUTION STRUCTURE OF THE FIRST SAM DOMAIN OF ODIN
Descriptor:Ankyrin repeat and SAM domain-containing protein 1A
Authors:Leone, M., Mercurio, F.
Deposit date:2011-12-12
Release date:2012-03-14
Last modified:2012-03-28
Method:SOLUTION NMR
Cite:Solution Structure of the First Sam Domain of Odin and Binding Studies with the EphA2 Receptor.
Biochemistry, 51, 2012
6F7O
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NMR STRUCTURE OF AN ODIN-SAM1 STAPLED PEPTIDE
Descriptor:Ankyrin repeat and SAM domain-containing protein 1A
Authors:Leone, M., Mercurio, F.A.
Deposit date:2017-12-11
Release date:2018-08-01
Method:SOLUTION NMR
Cite:Sam domain-based stapled peptides: Structural analysis and interaction studies with the Sam domains from the EphA2 receptor and the lipid phosphatase Ship2.
Bioorg. Chem., 80, 2018
1NJQ
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NMR STRUCTURE OF THE SINGLE QALGGH ZINC FINGER DOMAIN FROM ARABIDOPSIS THALIANA SUPERMAN PROTEIN
Descriptor:superman protein, ZINC ION
Authors:Isernia, C., Bucci, E., Leone, M., Zaccaro, L., Di Lello, P., Digilio, G., Esposito, S., Saviano, M., Di Blasio, B., Pedone, C., Pedone, P.V., Fattorusso, R.
Deposit date:2003-01-02
Release date:2003-03-04
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:NMR Structure of the Single QALGGH Zinc Finger Domain from the Arabidopsis thaliana SUPERMAN Protein.
Chembiochem, 4, 2003
2A25
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CRYSTAL STRUCTURE OF SIAH1 SBD BOUND TO THE PEPTIDE EKPAAVVAPITTG FROM SIP
Descriptor:Ubiquitin ligase SIAH1, Calcyclin-binding protein peptide, ZINC ION
Authors:Santelli, E., Leone, M., Li, C., Fukushima, T., Preece, N.E., Olson, A.J., Ely, K.R., Reed, J.C., Pellecchia, M., Liddington, R.C., Matsuzawa, S.
Deposit date:2005-06-21
Release date:2005-08-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Analysis of Siah1-Siah-interacting Protein Interactions and Insights into the Assembly of an E3 Ligase Multiprotein Complex
J.Biol.Chem., 280, 2005
2A26
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CRYSTAL STRUCTURE OF THE N-TERMINAL, DIMERIZATION DOMAIN OF SIAH INTERACTING PROTEIN
Descriptor:Calcyclin-binding protein, SULFATE ION, 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID
Authors:Santelli, E., Leone, M., Li, C., Fukushima, T., Preece, N.E., Olson, A.J., Ely, K.R., Reed, J.C., Pellecchia, M., Liddington, R.C., Matsuzawa, S.
Deposit date:2005-06-21
Release date:2005-08-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Structural Analysis of Siah1-Siah-interacting Protein Interactions and Insights into the Assembly of an E3 Ligase Multiprotein Complex
J.Biol.Chem., 280, 2005
2L1O
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ZINC TO CADMIUM REPLACEMENT IN THE A. THALIANA SUPERMAN CYS2HIS2 ZINC FINGER INDUCES STRUCTURAL REARRANGEMENTS OF TYPICAL DNA BASE DETERMINANT POSITIONS
Descriptor:Transcriptional regulator SUPERMAN, CADMIUM ION
Authors:Malgieri, G., Zaccaro, L., Leone, M., Bucci, E., Esposito, S., Baglivo, I., Del Gatto, A., Scandurra, R., Pedone, P.V., Fattorusso, R., Isernia, C.
Deposit date:2010-07-31
Release date:2011-06-08
Last modified:2011-12-21
Method:SOLUTION NMR
Cite:Zinc to cadmium replacement in the A. thaliana SUPERMAN Cys(2) His(2) zinc finger induces structural rearrangements of typical DNA base determinant positions.
Biopolymers, 95, 2011
2MYQ
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NMR STRUCTURE OF AN ODIN-SAM1 FRAGMENT
Descriptor:Ankyrin repeat and SAM domain-containing protein 1A
Authors:Mercurio, F.A., Leone, M.
Deposit date:2015-01-30
Release date:2015-07-08
Last modified:2015-08-05
Method:SOLUTION NMR
Cite:Peptide Fragments of Odin-Sam1: Conformational Analysis and Interaction Studies with EphA2-Sam.
Chembiochem, 16, 2015
5NZ9
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NMR STRUCTURE OF AN EPHA2-SAM FRAGMENT
Descriptor:Ephrin type-A receptor 2
Authors:Mercurio, F.A., Leone, M.
Deposit date:2017-05-12
Release date:2017-12-20
Last modified:2017-12-27
Method:SOLUTION NMR
Cite:The Sam-Sam interaction between Ship2 and the EphA2 receptor: design and analysis of peptide inhibitors.
Sci Rep, 7, 2017
6F7M
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NMR STRUCTURE OF EPHA2-SAM STAPLED PEPTIDES (S13ST)
Descriptor:Ephrin type-A receptor 2
Authors:Mercurio, F.A., Leone, M.
Deposit date:2017-12-11
Release date:2018-08-01
Method:SOLUTION NMR
Cite:Sam domain-based stapled peptides: Structural analysis and interaction studies with the Sam domains from the EphA2 receptor and the lipid phosphatase Ship2.
Bioorg. Chem., 80, 2018
6F7N
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NMR STRUCTURE OF EPHA2-SAM STAPLED PEPTIDES (S13STSHORT)
Descriptor:Ephrin type-A receptor 2
Authors:Mercurio, F.A., Leone, M.
Deposit date:2017-12-11
Release date:2018-08-01
Method:SOLUTION NMR
Cite:Sam domain-based stapled peptides: Structural analysis and interaction studies with the Sam domains from the EphA2 receptor and the lipid phosphatase Ship2.
Bioorg. Chem., 80, 2018
6FS4
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NMR STRUCTURE OF CASOCIDIN-II ANTIMICROBIAL PEPTIDE IN 60% TFE
Descriptor:Alpha-S2-casein
Authors:Mercurio, F.A., Leone, M.
Deposit date:2018-02-19
Release date:2018-10-03
Method:SOLUTION NMR
Cite:The antimicrobial peptides casocidins I and II: solution structural studies in water and different membrane-mimetic environments.
Peptides, 2018
6FS5
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NMR STRUCTURE OF CASOCIDIN-I ANTIMICROBIAL PEPTIDE IN 60% TFE
Descriptor:Alpha-S2-casein
Authors:Mercurio, F.A., Leone, M.
Deposit date:2018-02-19
Release date:2018-10-03
Method:SOLUTION NMR
Cite:The antimicrobial peptides casocidins I and II: solution structural studies in water and different membrane-mimetic environments.
Peptides, 2018
5NHU
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HUMAN ALPHA THROMBIN COMPLEXED WITH ANOPHELES GAMBIAE CE5 ANTICOAGULANT
Descriptor:Prothrombin, AGAP008004-PA, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Ripoll-Rozada, J., Pereira, P.J.B.
Deposit date:2017-03-22
Release date:2017-06-14
Last modified:2017-08-09
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Functional analyses yield detailed insight into the mechanism of thrombin inhibition by the antihemostatic salivary protein cE5 from Anopheles gambiae.
J. Biol. Chem., 292, 2017
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