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4V94
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BU of 4v94 by Molmil
Molecular architecture of the eukaryotic chaperonin TRiC/CCT derived by a combination of chemical crosslinking and mass-spectrometry, XL-MS
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ...
Authors:Leitner, A, Joachimiak, L.A, Bracher, A, Walzthoeni, T, Chen, B, Monkemeyer, L, Pechmann, S, Holmes, S, Cong, Y, Ma, B, Ludtke, S, Chiu, W, Hartl, F.U, Aebersold, R, Frydman, J.
Deposit date:2012-01-11
Release date:2014-07-09
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:The Molecular Architecture of the Eukaryotic Chaperonin TRiC/CCT.
Structure, 20, 2012
4V19
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BU of 4v19 by Molmil
Structure of the large subunit of the mammalian mitoribosome, part 1 of 2
Descriptor: MAGNESIUM ION, MITORIBOSOMAL 16S RRNA, MITORIBOSOMAL CP TRNA, ...
Authors:Greber, B.J, Boehringer, D, Leibundgut, M, Bieri, P, Leitner, A, Schmitz, N, Aebersold, R, Ban, N.
Deposit date:2014-09-25
Release date:2014-10-08
Last modified:2019-10-23
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:The Complete Structure of the Large Subunit of the Mammalian Mitochondrial Ribosome
Nature, 515, 2014
7SX4
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BU of 7sx4 by Molmil
Human NALCN-FAM155A-UNC79-UNC80 channelosome with CaM bound, conformation 2/2
Descriptor: (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Kschonsak, M, Chua, H.C, Weidling, C, Chakouri, N, Noland, C.L, Schott, K, Chang, T, Tam, C, Patel, N, Arthur, C.P, Leitner, A, Ben-Johny, M, Ciferri, C, Pless, S.A, Payandeh, J.
Deposit date:2021-11-22
Release date:2021-12-29
Last modified:2022-03-16
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural architecture of the human NALCN channelosome.
Nature, 603, 2022
7SX3
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BU of 7sx3 by Molmil
Human NALCN-FAM155A-UNC79-UNC80 channelosome with CaM bound, conformation 1/2
Descriptor: (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Kschonsak, M, Chua, H.C, Weidling, C, Chakouri, N, Noland, C.L, Schott, K, Chang, T, Tam, C, Patel, N, Arthur, C.P, Leitner, A, Ben-Johny, M, Ciferri, C, Pless, S.A, Payandeh, J.
Deposit date:2021-11-22
Release date:2021-12-29
Last modified:2022-03-16
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural architecture of the human NALCN channelosome.
Nature, 603, 2022
7LUP
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BU of 7lup by Molmil
Human TRiC/CCT complex with reovirus outer capsid protein sigma-3
Descriptor: Outer capsid protein sigma-3, T-complex protein 1 subunit alpha, T-complex protein 1 subunit beta, ...
Authors:Knowlton, J.J, Gestaut, D, Ma, B, Taylor, G, Seven, A.B, Leitner, A, Wilson, G.J, Shanker, S, Yates, N.A, Prasad, B.V.V, Aebersold, R, Chiu, W, Frydman, J, Dermody, T.S.
Deposit date:2021-02-22
Release date:2021-03-03
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (6.2 Å)
Cite:Structural and functional dissection of reovirus capsid folding and assembly by the prefoldin-TRiC/CCT chaperone network.
Proc.Natl.Acad.Sci.USA, 118, 2021
7LUM
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BU of 7lum by Molmil
Human TRiC in ATP/AlFx closed state
Descriptor: T-complex protein 1 subunit alpha, T-complex protein 1 subunit beta, T-complex protein 1 subunit delta, ...
Authors:Knowlton, J.J, Gestaut, D, Ma, B, Taylor, G, Seven, A.B, Leitner, A, Wilson, G.J, Shanker, S, Yates, N.A, Prasad, B.V.V, Aebersold, R, Chiu, W, Frydman, J, Dermody, T.S.
Deposit date:2021-02-22
Release date:2021-03-03
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Structural and functional dissection of reovirus capsid folding and assembly by the prefoldin-TRiC/CCT chaperone network.
Proc.Natl.Acad.Sci.USA, 118, 2021
5AJ3
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BU of 5aj3 by Molmil
Structure of the small subunit of the mammalian mitoribosome
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, MITORIBOSOMAL 12S RRNA, ...
Authors:Greber, B.J, Bieri, P, Leibundgut, M, Leitner, A, Aebersold, R, Boehringer, D, Ban, N.
Deposit date:2015-02-20
Release date:2015-04-22
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Ribosome. The complete structure of the 55S mammalian mitochondrial ribosome.
Science, 348, 2015
5AJ4
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BU of 5aj4 by Molmil
Structure of the 55S mammalian mitoribosome.
Descriptor: 28S RIBOSOMAL PROTEIN S18B, MITOCHONDRIAL, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Greber, B.J, Bieri, P, Leibundgut, M, Leitner, A, Aebersold, R, Boehringer, D, Ban, N.
Deposit date:2015-02-20
Release date:2015-04-22
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:The complete structure of the 55S mammalian mitochondrial ribosome.
Science, 348, 2015
5APO
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BU of 5apo by Molmil
Structure of the yeast 60S ribosomal subunit in complex with Arx1, Alb1 and C-terminally tagged Rei1
Descriptor: 25S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Greber, B.J, Gerhardy, S, Leitner, A, Leibundgut, M, Salem, M, Boehringer, D, Leulliot, N, Aebersold, R, Panse, V.G, Ban, N.
Deposit date:2015-09-17
Release date:2015-12-16
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.41 Å)
Cite:Insertion of the Biogenesis Factor Rei1 Probes the Ribosomal Tunnel during 60S Maturation.
Cell(Cambridge,Mass.), 164, 2016
6SG9
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BU of 6sg9 by Molmil
Head domain of the mt-SSU assemblosome from Trypanosoma brucei
Descriptor: 9S rRNA, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Saurer, M, Ramrath, D.J.F, Niemann, M, Calderaro, S, Prange, C, Mattei, S, Scaiola, A, Leitner, A, Bieri, P, Horn, E.K, Leibundgut, M, Boehringer, D, Schneider, A, Ban, N.
Deposit date:2019-08-03
Release date:2019-09-18
Last modified:2019-09-25
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Mitoribosomal small subunit biogenesis in trypanosomes involves an extensive assembly machinery.
Science, 365, 2019
5APN
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BU of 5apn by Molmil
Structure of the yeast 60S ribosomal subunit in complex with Arx1, Alb1 and N-terminally tagged Rei1
Descriptor: 25S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Greber, B.J, Gerhardy, S, Leitner, A, Leibundgut, M, Salem, M, Boehringer, D, Leulliot, N, Aebersold, R, Panse, V.G, Ban, V.
Deposit date:2015-09-17
Release date:2015-12-16
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.91 Å)
Cite:Insertion of the Biogenesis Factor Rei1 Probes the Ribosomal Tunnel during 60S Maturation.
Cell, 164, 2015
6SGA
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BU of 6sga by Molmil
Body domain of the mt-SSU assemblosome from Trypanosoma brucei
Descriptor: 9S rRNA, MAGNESIUM ION, PHOSPHATE ION, ...
Authors:Saurer, M, Ramrath, D.J.F, Niemann, M, Calderaro, S, Prange, C, Mattei, S, Scaiola, A, Leitner, A, Bieri, P, Horn, E.K, Leibundgut, M, Boehringer, D, Schneider, A, Ban, N.
Deposit date:2019-08-03
Release date:2019-09-18
Last modified:2019-09-25
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Mitoribosomal small subunit biogenesis in trypanosomes involves an extensive assembly machinery.
Science, 365, 2019
6SGB
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BU of 6sgb by Molmil
mt-SSU assemblosome of Trypanosoma brucei
Descriptor: 9S rRNA, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Saurer, M, Ramrath, D.J.F, Niemann, M, Calderaro, S, Prange, C, Mattei, S, Scaiola, A, Leitner, A, Bieri, P, Horn, E.K, Leibundgut, M, Boehringer, D, Schneider, A, Ban, N.
Deposit date:2019-08-03
Release date:2019-09-25
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Mitoribosomal small subunit biogenesis in trypanosomes involves an extensive assembly machinery.
Science, 365, 2019
4QCJ
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BU of 4qcj by Molmil
Crystal Structure of OdhI from Corynebacterium glutamicum
Descriptor: Oxoglutarate dehydrogenase inhibitor
Authors:Labahn, J, Raasch, K, Eggeling, L, Bocola, M, Leitner, A, Bott, M.
Deposit date:2014-05-12
Release date:2014-07-02
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Interaction of 2-oxoglutarate dehydrogenase OdhA with its inhibitor OdhI in Corynebacterium glutamicum: Mutants and a model.
J.Biotechnol., 191, 2014
4CE4
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BU of 4ce4 by Molmil
39S large subunit of the porcine mitochondrial ribosome
Descriptor: 16S Ribosomal RNA, ICT1, MRPL13, ...
Authors:Greber, B.J, Boehringer, D, Leitner, A, Bieri, P, Voigts-Hoffmann, F, Erzberger, J.P, Leibundgut, M, Aebersold, R, Ban, N.
Deposit date:2013-11-08
Release date:2013-12-18
Last modified:2019-04-10
Method:ELECTRON MICROSCOPY (4.9 Å)
Cite:Architecture of the Large Subunit of the Mammalian Mitochondrial Ribosome.
Nature, 505, 2014
4UWA
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BU of 4uwa by Molmil
Structure of the ryanodine receptor at resolution of 6.1 A in closed state
Descriptor: RYANODINE RECEPTOR 1
Authors:Efremov, R.G, Leitner, A, Aebersold, R, Raunser, S.
Deposit date:2014-08-11
Release date:2014-12-10
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (6.1 Å)
Cite:Architecture and Conformational Switch Mechanism of the Ryanodine Receptor.
Nature, 517, 2015
4V1A
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BU of 4v1a by Molmil
Structure of the large subunit of the mammalian mitoribosome, part 2 of 2
Descriptor: MITORIBOSOMAL PROTEIN ML37, MRPL37, MITORIBOSOMAL PROTEIN ML38, ...
Authors:Greber, B.J, Boehringer, D, Leibundgut, M, Bieri, P, Leitner, A, Schmitz, N, Aebersold, R, Ban, N.
Deposit date:2014-09-25
Release date:2014-10-08
Last modified:2019-10-02
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:The Complete Structure of the Large Subunit of the Mammalian Mitochondrial Ribosome
Nature, 515, 2014
4UWE
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BU of 4uwe by Molmil
Structure of the ryanodine receptor at resolution of 8.5 A in partially open state
Descriptor: RYANODINE RECEPTOR 1
Authors:Efremov, R.G, Leitner, A, Aebersold, R, Raunser, S.
Deposit date:2014-08-11
Release date:2014-12-10
Last modified:2017-08-30
Method:ELECTRON MICROSCOPY (8.5 Å)
Cite:Architecture and Conformational Switch Mechanism of the Ryanodine Receptor.
Nature, 517, 2015
6HIZ
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BU of 6hiz by Molmil
Cryo-EM structure of the Trypanosoma brucei mitochondrial ribosome - This entry contains the head of the small mitoribosomal subunit
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, RNA (143-MER), ...
Authors:Ramrath, D.J.F, Niemann, M, Leibundgut, M, Bieri, P, Prange, C, Horn, E.K, Leitner, A, Boehringer, A, Schneider, A, Ban, N.
Deposit date:2018-08-31
Release date:2018-09-26
Last modified:2018-11-07
Method:ELECTRON MICROSCOPY (3.08 Å)
Cite:Evolutionary shift toward protein-based architecture in trypanosomal mitochondrial ribosomes.
Science, 362, 2018
7WU7
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BU of 7wu7 by Molmil
Prefoldin-tubulin-TRiC complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Prefoldin subunit 1, Prefoldin subunit 2, ...
Authors:Gestaut, D, Zhao, Y, Park, J, Ma, B, Leitner, A, Collier, M, Pintilie, G, Roh, S.-H, Chiu, W, Frydman, J.
Deposit date:2022-02-07
Release date:2022-12-21
Method:ELECTRON MICROSCOPY (3.85 Å)
Cite:Structural visualization of the tubulin folding pathway directed by human chaperonin TRiC/CCT.
Cell, 185, 2022
6HIV
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BU of 6hiv by Molmil
Cryo-EM structure of the Trypanosoma brucei mitochondrial ribosome - This entry contains the complete mitoribosome
Descriptor: 12S rRNA, 50S ribosomal protein L13, putative, ...
Authors:Ramrath, D.J.F, Niemann, M, Leibundgut, M, Bieri, P, Prange, C, Horn, E.K, Leitner, A, Boerhringer, D, Schneider, A, Ban, N.
Deposit date:2018-08-31
Release date:2018-10-03
Last modified:2018-11-07
Method:ELECTRON MICROSCOPY (7.8 Å)
Cite:Evolutionary shift toward protein-based architecture in trypanosomal mitochondrial ribosomes.
Science, 362, 2018
6HIY
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BU of 6hiy by Molmil
Cryo-EM structure of the Trypanosoma brucei mitochondrial ribosome - This entry contains the body of the small mitoribosomal subunit in complex with mt-IF-3
Descriptor: 9S rRNA, MAGNESIUM ION, SPERMIDINE, ...
Authors:Ramrath, D.J.F, Niemann, M, Leibundgut, M, Bieri, P, Prange, C, Horn, E.K, Leitner, A, Boehringer, D, Schneider, A, Ban, N.
Deposit date:2018-08-31
Release date:2018-09-26
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.27 Å)
Cite:Evolutionary shift toward protein-based architecture in trypanosomal mitochondrial ribosomes.
Science, 362, 2018
6HIX
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BU of 6hix by Molmil
Cryo-EM structure of the Trypanosoma brucei mitochondrial ribosome - This entry contains the large mitoribosomal subunit
Descriptor: 12S rRNA, 50S ribosomal protein L13, putative, ...
Authors:Ramrath, D.J.F, Niemann, M, Leibundgut, M, Bieri, P, Prange, C, Horn, K, Leitner, A, Boehringer, D, Schneider, A, Ban, N.
Deposit date:2018-08-31
Release date:2018-09-26
Last modified:2019-02-06
Method:ELECTRON MICROSCOPY (3.39 Å)
Cite:Evolutionary shift toward protein-based architecture in trypanosomal mitochondrial ribosomes.
Science, 362, 2018
6HIW
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BU of 6hiw by Molmil
Cryo-EM structure of the Trypanosoma brucei mitochondrial ribosome - This entry contains the complete small mitoribosomal subunit in complex with mt-IF-3
Descriptor: 9S rRNA, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Ramrath, D, Niemann, M, Leibundgut, M, Bieri, P, Prange, C, Horn, E.K, Leitner, A, Boehringer, D, Schneider, A, Ban, N.
Deposit date:2018-08-31
Release date:2018-09-26
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.37 Å)
Cite:Evolutionary shift toward protein-based architecture in trypanosomal mitochondrial ribosomes.
Science, 362, 2018
6NRB
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BU of 6nrb by Molmil
hTRiC-hPFD Class2
Descriptor: Prefoldin subunit 1, Prefoldin subunit 2, Prefoldin subunit 3, ...
Authors:Gestaut, D.R, Roh, S.H, Ma, B, Pintilie, G, Joachimiak, L.A, Leitner, A, Walzthoeni, T, Aebersold, R, Chiu, W, Frydman, J.
Deposit date:2019-01-23
Release date:2019-06-19
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (8.7 Å)
Cite:The Chaperonin TRiC/CCT Associates with Prefoldin through a Conserved Electrostatic Interface Essential for Cellular Proteostasis.
Cell, 177, 2019

 

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