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2F1K
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CRYSTAL STRUCTURE OF SYNECHOCYSTIS AROGENATE DEHYDROGENASE
Descriptor:prephenate dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
Authors:Legrand, P., Dumas, R., Seux, M., Rippert, P., Ravelli, R., Ferrer, J.-L., Matringe, M.
Deposit date:2005-11-14
Release date:2006-05-09
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Biochemical Characterization and Crystal Structure of Synechocystis Arogenate Dehydrogenase Provide Insights into Catalytic Reaction
Structure, 14, 2006
2UY1
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CRYSTAL STRUCTURE OF CSTF-77
Descriptor:CLEAVAGE STIMULATION FACTOR 77
Authors:Legrand, P., Pinaud, N., Minvielle-Sebastia, L., Fribourg, S.
Deposit date:2007-04-02
Release date:2007-07-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Structure of the Cstf-77 Homodimer Provides Insights Into Cstf Assembly.
Nucleic Acids Res., 35, 2007
5E7B
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STRUCTURE OF A NANOBODY (VHH) FROM CAMEL AGAINST PHAGE TUC2009 RBP (BPPL, ORF53)
Descriptor:nanobody nano-L06
Authors:Legrand, P., Collins, B., Blangy, S., Murphy, J., Spinelli, S., Gutierrez, C., Richet, N., Kellenberger, C., Desmyter, A., Mahony, J., van Sinderen, D., Cambillau, C.
Deposit date:2015-10-12
Release date:2015-12-30
Last modified:2016-05-04
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:The Atomic Structure of the Phage Tuc2009 Baseplate Tripod Suggests that Host Recognition Involves Two Different Carbohydrate Binding Modules.
Mbio, 7, 2016
5E7F
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COMPLEX BETWEEN LACTOCOCCAL PHAGE TUC2009 RBP HEAD DOMAIN AND A NANOBODY (L06)
Descriptor:nanobody L06, Major structural protein 1
Authors:Legrand, P., Collins, B., Blangy, S., Murphy, J., Spinelli, S., Gutierrez, C., Richet, N., Kellenberger, C., Desmyter, A., Mahony, J., van Sinderen, D., Cambillau, C.
Deposit date:2015-10-12
Release date:2015-12-30
Last modified:2018-10-24
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The Atomic Structure of the Phage Tuc2009 Baseplate Tripod Suggests that Host Recognition Involves Two Different Carbohydrate Binding Modules.
Mbio, 7, 2016
5E7T
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STRUCTURE OF THE TRIPOD (BPPUCT-A-L) FROM THE BASEPLATE OF BACTERIOPHAGE TUC2009
Descriptor:Minor structural protein 4, Minor structural protein 5, Major structural protein 1, ...
Authors:Legrand, P., Collins, B., Blangy, S., Murphy, J., Spinelli, S., Gutierrez, C., Richet, N., Kellenberger, C., Desmyter, A., Mahony, J., van Sinderen, D., Cambillau, C.
Deposit date:2015-10-13
Release date:2015-12-30
Last modified:2016-05-04
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The Atomic Structure of the Phage Tuc2009 Baseplate Tripod Suggests that Host Recognition Involves Two Different Carbohydrate Binding Modules.
Mbio, 7, 2016
4A6D
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CRYSTAL STRUCTURE OF HUMAN N-ACETYLSEROTONIN METHYLTRANSFERASE (ASMT) IN COMPLEX WITH SAM
Descriptor:HYDROXYINDOLE O-METHYLTRANSFERASE, ZINC ION, S-ADENOSYLMETHIONINE, ...
Authors:Legrand, P., Haouz, A., Shepard, W.
Deposit date:2011-11-01
Release date:2012-11-07
Last modified:2013-08-28
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structure and Functional Mapping of Human Asmt, the Last Enzyme of the Melatonin Synthesis Pathway.
J.Pineal Res., 54, 2013
4A6E
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CRYSTAL STRUCTURE OF HUMAN N-ACETYLSEROTONIN METHYLTRANSFERASE (ASMT) IN COMPLEX WITH SAM AND N-ACETYLSEROTONIN
Descriptor:HYDROXYINDOLE O-METHYLTRANSFERASE, ZINC ION, S-ADENOSYLMETHIONINE, ...
Authors:Legrand, P., Haouz, A., Shepard, W.
Deposit date:2011-11-01
Release date:2012-11-07
Last modified:2013-08-28
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal Structure and Functional Mapping of Human Asmt, the Last Enzyme of the Melatonin Synthesis Pathway.
J.Pineal Res., 54, 2013
2V94
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CRYSTAL STRUCTURE OF P. ABYSSI RPS24
Descriptor:30S RIBOSOMAL PROTEIN S24E
Authors:Legrand, P., Pinaud, N., Gleizes, P.E., Fribourg, S.
Deposit date:2007-08-21
Release date:2008-04-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Mutation of Ribosomal Protein Rps24 in Diamond- Blackfan Anemia Results in a Ribosome Biogenesis Disorder.
Hum.Mol.Genet., 17, 2008
4D5M
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GONADOTROPIN-RELEASING HORMONE AGONIST
Descriptor:TRIPTORELIN, PHOSPHATE ION
Authors:Legrand, P., Le Du, M.-H., Valery, C., Deville-Foillard, S., Paternostre, M., Artzner, F.
Deposit date:2014-11-05
Release date:2015-08-12
Method:X-RAY DIFFRACTION (0.85 Å)
Cite:Atomic View of the Histidine Environment Stabilizing Higher- Ph Conformations of Ph-Dependent Proteins.
Nat.Commun., 6, 2015
1MRQ
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CRYSTAL STRUCTURE OF HUMAN 20ALPHA-HSD IN TERNARY COMPLEX WITH NADP AND 20ALPHA-HYDROXY-PROGESTERONE
Descriptor:Aldo-keto reductase family 1 member C1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PROGESTERONE, ...
Authors:Couture, J.F., Legrand, P., Cantin, L., Luu-The, V., Labrie, F., Breton, R.
Deposit date:2002-09-18
Release date:2003-09-30
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Human 20alpha-hydroxysteroid dehydrogenase: crystallographic and site-directed mutagenesis studies lead to the identification of an alternative binding site for C21-steroids.
J.Mol.Biol., 331, 2003
3Q4F
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CRYSTAL STRUCTURE OF XRCC4/XLF-CERNUNNOS COMPLEX
Descriptor:Non-homologous end-joining factor 1, DNA repair protein XRCC4
Authors:Ropars, V., Legrand, P., Charbonnier, J.B.
Deposit date:2010-12-23
Release date:2011-08-03
Last modified:2011-11-02
Method:X-RAY DIFFRACTION (5.5 Å)
Cite:Structural characterization of filaments formed by human Xrcc4-Cernunnos/XLF complex involved in nonhomologous DNA end-joining.
Proc.Natl.Acad.Sci.USA, 108, 2011
5OLL
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CRYSTAL STRUCTURE OF GURMARIN, A SWEET TASTE SUPPRESSING POLYPEPTIDE
Descriptor:Gurmarin, NICKEL (II) ION
Authors:Sigoillot, M., Neiers, F., Legrand, P., Roblin, P., Briand, L.
Deposit date:2017-07-28
Release date:2018-08-08
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:The Crystal Structure of Gurmarin, a Sweet Taste-Suppressing Protein: Identification of the Amino Acid Residues Essential for Inhibition.
Chem. Senses, 43, 2018
6ERF
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COMPLEX OF APLF FACTOR AND KU HETERODIMER BOUND TO DNA
Descriptor:X-ray repair cross-complementing protein 6, X-ray repair cross-complementing protein 5, DNA (5'-D(*GP*TP*TP*TP*TP*TP*AP*GP*TP*TP*TP*AP*TP*TP*GP*GP*GP*CP*GP*CP*G)-3'), ...
Authors:Nemoz, C., Legrand, P., Ropars, V., Charbonnier, J.B.
Deposit date:2017-10-18
Release date:2018-10-17
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:XLF and APLF bind Ku80 at two remote sites to ensure DNA repair by non-homologous end joining.
Nat. Struct. Mol. Biol., 25, 2018
6ERG
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COMPLEX OF XLF AND HETERODIMER KU BOUND TO DNA
Descriptor:X-ray repair cross-complementing protein 6, X-ray repair cross-complementing protein 5, Non-homologous end-joining factor 1, ...
Authors:Nemoz, C., Legrand, P., Ropars, V., Charbonnier, J.B.
Deposit date:2017-10-18
Release date:2018-10-17
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:XLF and APLF bind Ku80 at two remote sites to ensure DNA repair by non-homologous end joining.
Nat. Struct. Mol. Biol., 25, 2018
6ERH
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COMPLEX OF XLF AND HETERODIMER KU BOUND TO DNA
Descriptor:X-ray repair cross-complementing protein 6, X-ray repair cross-complementing protein 5, DNA (34-MER), ...
Authors:Nemoz, C., Legrand, P., Ropars, V., Charbonnier, J.B.
Deposit date:2017-10-18
Release date:2018-10-17
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:XLF and APLF bind Ku80 at two remote sites to ensure DNA repair by non-homologous end joining.
Nat. Struct. Mol. Biol., 25, 2018
2V7F
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STRUCTURE OF P. ABYSSI RPS19 PROTEIN
Descriptor:RPS19E SSU RIBOSOMAL PROTEIN S19E, CHLORIDE ION
Authors:Gregory, L.A., Aguissa-Toure, A.H., Pinaud, N., Legrand, P., Gleizes, P.E., Fribourg, S.
Deposit date:2007-07-30
Release date:2007-09-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Molecular Basis of Diamond Blackfan Anemia: Structure and Function Analysis of Rps19.
Nucleic Acids Res., 35, 2007
2YOE
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X-RAY STRUCTURE OF A PENTAMERIC LIGAND GATED ION CHANNEL FROM ERWINIA CHRYSANTHEMI (ELIC) IN COMPLEX WITH GABA AND FLURAZEPAM
Descriptor:CYS-LOOP LIGAND-GATED ION CHANNEL, GAMMA-AMINO-BUTANOIC ACID, Flurazepam
Authors:Spurny, R., Brams, M., Nury, H., Legrand, P., Ulens, C.
Deposit date:2012-10-23
Release date:2012-10-31
Last modified:2012-11-14
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Pentameric Ligand-Gated Ion Channel Elic is Activated by Gaba and Modulated by Benzodiazepines.
Proc.Natl.Acad.Sci.USA, 109, 2012
4A98
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X-RAY STRUCTURE OF A PENTAMERIC LIGAND GATED ION CHANNEL FROM ERWINIA CHRYSANTHEMI (ELIC) IN COMPLEX WITH BROMOFLURAZEPAM
Descriptor:CYS-LOOP LIGAND-GATED ION CHANNEL, 7-BROMO-1-[2-(DIETHYLAMINO)ETHYL]-5-(2-FLUOROPHENYL)-1,3-DIHYDRO-2H-1,4-BENZODIAZEPIN-2-ONE
Authors:Spurny, R., Brams, M., Nury, H., Legrand, P., Ulens, C.
Deposit date:2011-11-24
Release date:2012-10-17
Last modified:2012-11-14
Method:X-RAY DIFFRACTION (3.61 Å)
Cite:Pentameric Ligand-Gated Ion Channel Elic is Activated by Gaba and Modulated by Benzodiazepines.
Proc.Natl.Acad.Sci.USA, 109, 2012
4E4W
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STRUCTURE OF THE C-TERMINAL DOMAIN OF THE SACCHAROMYCES CEREVISIAE MUTL ALPHA (MLH1/PMS1) HETERODIMER
Descriptor:DNA mismatch repair protein MLH1, DNA mismatch repair protein PMS1, GLYCEROL, ...
Authors:Gueneau, E., Legrand, P., Charbonnier, J.B.
Deposit date:2012-03-13
Release date:2013-02-20
Last modified:2013-06-19
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of the MutLalpha C-terminal domain reveals how Mlh1 contributes to Pms1 endonuclease site.
Nat.Struct.Mol.Biol., 20, 2013
4FMN
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STRUCTURE OF THE C-TERMINAL DOMAIN OF THE SACCHAROMYCES CEREVISIAE MUTL ALPHA (MLH1/PMS1) HETERODIMER BOUND TO A FRAGMENT OF NTG2
Descriptor:DNA mismatch repair protein MLH1, DNA mismatch repair protein PMS1, DNA repair peptide, ...
Authors:Gueneau, E., Legrand, P., Charbonnier, J.B.
Deposit date:2012-06-18
Release date:2013-02-20
Last modified:2013-08-28
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:Structure of the MutL alpha C-terminal domain reveals how Mlh1 contributes to Pms1 endonuclease site.
Nat.Struct.Mol.Biol., 20, 2013
4FMO
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STRUCTURE OF THE C-TERMINAL DOMAIN OF THE SACCHAROMYCES CEREVISIAE MUTL ALPHA (MLH1/PMS1) HETERODIMER BOUND TO A FRAGMENT OF EXO1
Descriptor:DNA mismatch repair protein MLH1, DNA mismatch repair protein PMS1, DNA repair peptide, ...
Authors:Gueneau, E., Legrand, P., Charbonnier, J.B.
Deposit date:2012-06-18
Release date:2013-02-20
Last modified:2013-08-28
Method:X-RAY DIFFRACTION (3.04 Å)
Cite:Structure of the MutL alpha C-terminal domain reveals how Mlh1 contributes to Pms1 endonuclease site.
Nat.Struct.Mol.Biol., 20, 2013
1EYX
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CRYSTAL STRUCTURE OF R-PHYCOERYTHRIN AT 2.2 ANGSTROMS
Descriptor:R-PHYCOERYTHRIN, SULFATE ION, BILIVERDINE IX ALPHA, ...
Authors:Contreras-Martel, C., Legrand, P., Piras, C., Vernede, X., Martinez-Oyanedel, J., Bunster, M., Fontecilla-Camps, J.C.
Deposit date:2000-05-09
Release date:2000-11-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystallization and 2.2 A resolution structure of R-phycoerythrin from Gracilaria chilensis: a case of perfect hemihedral twinning.
Acta Crystallogr.,Sect.D, 57, 2001
1HFE
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1.6 A RESOLUTION STRUCTURE OF THE FE-ONLY HYDROGENASE FROM DESULFOVIBRIO DESULFURICANS
Descriptor:PROTEIN (FE-ONLY HYDROGENASE (E.C.1.18.99.1) (SMALLER SUBUNIT)), PROTEIN (FE-ONLY HYDROGENASE (E.C.1.18.99.1) (LARGER SUBUNIT)), ZINC ION, ...
Authors:Nicolet, Y., Piras, C., Legrand, P., Hatchikian, E.C., Fontecilla-Camps, J.C.
Deposit date:1998-11-11
Release date:1999-04-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Desulfovibrio desulfuricans iron hydrogenase: the structure shows unusual coordination to an active site Fe binuclear center.
Structure Fold.Des., 7, 1999
1OAO
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NIZN[FE4S4] AND NINI[FE4S4] CLUSTERS IN CLOSED AND OPEN ALPHA SUBUNITS OF ACETYL-COA SYNTHASE/CARBON MONOXIDE DEHYDROGENASE
Descriptor:CARBON MONOXIDE DEHYDROGENASE/ACETYL-COA SYNTHASE SUBUNIT BETA, CARBON MONOXIDE DEHYDROGENASE/ACETYL-COA SYNTHASE SUBUNIT ALPHA, IRON/SULFUR CLUSTER, ...
Authors:Darnault, C., Volbeda, A., Kim, E.J., Legrand, P., Vernede, X., Lindahl, P.A., Fontecilla-Camps, J.C.
Deposit date:2003-01-20
Release date:2003-04-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Ni-Zn-[Fe4-S4] and Ni-Ni-[Fe4-S4] Clusters in Closed and Open Alpha Subunits of Acetyl-Coa Synthase/Carbon Monoxide Dehydrogenase
Nat.Struct.Biol., 10, 2003
1Q13
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CRYSTAL STRUCTURE OF RABBIT 20ALPHA HYROXYSTEROID DEHYDROGENASE IN TERNARY COMPLEX WITH NADP AND TESTOSTERONE
Descriptor:Prostaglandin-E2 9-reductase, SULFATE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Couture, J.-F., Cantin, L., Legrand, P., Luu-The, V., Labrie, F., Breton, R.
Deposit date:2003-07-18
Release date:2004-11-16
Last modified:2017-12-20
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Loop relaxation, a mechanism that explains the reduced specificity of rabbit 20alpha-hydroxysteroid dehydrogenase, a member of the aldo-keto reductase superfamily.
J. Mol. Biol., 339, 2004