Author results

2GWE
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CRYSTAL STRUCTURE OF D(G4T4G4) WITH SIX QUADRUPLEXES IN THE ASYMMETRIC UNIT.
Descriptor:5'-D(*GP*GP*GP*GP*TP*TP*TP*TP*GP*GP*GP*G)-3', POTASSIUM ION
Authors:Lee, M.P.H., Haider, S., Parkinson, G.N., Neidle, S.
Deposit date:2006-05-04
Release date:2007-06-19
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of D(G4T4G4) with four and six quadruplexes in the asymmetric unit.
To be Published
2GWQ
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CRYSTAL STRUCTURE OF D(G4T4G4) WITH FOUR QUADRUPLEXES IN THE ASYMMETRIC UNIT.
Descriptor:5'-D(*GP*GP*GP*GP*TP*TP*TP*TP*GP*GP*GP*G)-3', POTASSIUM ION
Authors:Lee, M.P.H., Parkinson, G.N., Neidle, S.
Deposit date:2006-05-05
Release date:2007-06-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of D(G4T4G4) with four and six quadruplexes in the asymmetric unit.
To be Published
2I2I
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CRYSTAL STRUCTURE OF THE DB293-D(CGCGAATTCGCG)2 COMPLEX.
Descriptor:5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3', MAGNESIUM ION, 2-(5-{4-[AMINO(IMINO)METHYL]PHENYL}-2-FURYL)-1H-BENZIMIDAZOLE-5-CARBOXIMIDAMIDE
Authors:Lee, M.P.H., Neidle, S.
Deposit date:2006-08-16
Release date:2007-07-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Crystal structure of the DB293-D(CGCGAATTCGCG)2 complex.
To be Published
2NLM
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CRYSTAL STRUCTURE OF THE DB 911- D(CGCGAATTCGCG)2 COMPLEX AT 2.05 A RESOLUTION.
Descriptor:5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3', MAGNESIUM ION, 2-{4'-[AMINO(IMINO)METHYL]BIPHENYL-3-YL}-1H-BENZIMIDAZOLE-6-CARBOXIMIDAMIDE
Authors:Lee, M.P.H., Neidle, S.
Deposit date:2006-10-20
Release date:2007-10-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal structure of the DB 911 - D(CGCGAATTCGCG)2 complex at 2.05 A resolution.
To be Published
2GVR
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CRYSTAL STRUCTURE OF THE BERENIL-D(CGCGAATTCGCG)2 COMPLEX AT 1.65 A RESOLUTION.
Descriptor:5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3', BERENIL, MAGNESIUM ION
Authors:Lee, M.P.H., Parkinson, G.N., Neidle, S.
Deposit date:2006-05-03
Release date:2007-06-19
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal structure of the berenil-D(CGCGAATTCGCG)2 complex at 1.65 A resolution.
To be Published
2GYX
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CRYSTAL STRUCTURE OF DB884- D(CGCGAATTCGCG)2 COMPLEX AT 1.86 A RESOLUTION.
Descriptor:5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3', MAGNESIUM ION, N,N'-(1H-PYRROLE-2,5-DIYLDI-4,1-PHENYLENE)DIBENZENECARBOXIMIDAMIDE
Authors:Lee, M.P.H., Neidle, S.
Deposit date:2006-05-10
Release date:2007-05-22
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Induced fit conformational changes of a "reversed amidine" heterocycle: optimized interactions in a DNA minor groove complex.
J.Am.Chem.Soc., 129, 2007
1M6F
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STRONG BINDING IN THE DNA MINOR GROOVE BY AN AROMATIC DIAMIDINE WITH A SHAPE THAT DOES NOT MATCH THE CURVATURE OF THE GROOVE
Descriptor:DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3'), MAGNESIUM ION, 3-[C-[N'-(3-CARBAMIMIDOYL-BENZYLIDENIUM)-HYDRAZINO]-[[AMINOMETHYLIDENE]AMINIUM]-IMINOMETHYL]-BENZAMIDINIUM
Authors:Nguyen, B., Lee, M.P.H., Hamelberg, D., Joubert, A., Bailly, C., Brun, R., Neidle, S., Wilson, W.D.
Deposit date:2002-07-16
Release date:2002-11-15
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Strong Binding in the DNA Minor Groove by an Aromatic Diamidine With a Shape That Does Not Match the Curvature of the Groove
J.Am.Chem.Soc., 124, 2002
1VZK
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A THIOPHENE BASED DIAMIDINE FORMS A "SUPER" AT BINDING MINOR GROOVE AGENT
Descriptor:5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP *CP*G)-3', 2-(5-{4-[AMINO(IMINO)METHYL]PHENYL}-2-THIENYL)-1H-BENZIMIDAZOLE-6- CARBOXIMIDAMIDE DIHYDROCHLORIDE, MAGNESIUM ION
Authors:Mallena, S., Lee, M.P.H., Bailly, C., Neidle, S., Kumar, A., Boykin, D.W., Wilson, W.D.
Deposit date:2004-05-20
Release date:2004-10-25
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Thiophene-Based Diamidine Forms a "Super" at Binding Minor Groove Agent
J.Am.Chem.Soc., 142, 2004
2I5A
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CRYSTAL STRUCTURE OF A DB1055-D(CGCGAATTCGCG)2 COMPLEX
Descriptor:5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3', MAGNESIUM ION, 2-{3'-[AMINO(IMINO)METHYL]BIPHENYL-4-YL}-1H-BENZIMIDAZOLE-5-CARBOXIMIDAMIDE
Authors:Neidle, S., Lee, M.P.H.
Deposit date:2006-08-24
Release date:2008-04-08
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal structure of a DB1055-D(CGCGAATTCGCG)2 complex
To be Published
1K8P
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STRUCTURE OF THE HUMAN G-QUADRUPLEX REVEALS A NOVEL TOPOLOGY
Descriptor:5'-D(*(BRU)P*AP*GP*GP*GP*(BRU)P*TP*AP*GP*GP*GP*T)-3', POTASSIUM ION, SODIUM ION
Authors:Parkinson, G.N., Lee, M.P.H., Neidle, S.
Deposit date:2001-10-25
Release date:2002-05-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of parallel quadruplexes from human telomeric DNA.
Nature, 417, 2002
1KF1
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STRUCTURE AND PACKING OF HUMAN TELOMERIC DNA
Descriptor:5'-D(*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*G)-3, POTASSIUM ION
Authors:Parkinson, G.N., Lee, M.P.H., Neidle, S.
Deposit date:2001-11-19
Release date:2002-05-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of parallel quadruplexes from human telomeric DNA.
Nature, 417, 2002
2GW0
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A D(TGGGGT)- SODIUM AND CALCIUM COMPLEX.
Descriptor:5'-D(*TP*GP*GP*GP*GP*T)-3', SODIUM ION, CALCIUM ION
Authors:Lee, M.P.H., Parkinson, G.N., Neidle, S.
Deposit date:2006-05-03
Release date:2007-05-15
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Observation of the coexistence of sodium and calcium ions in a DNA G-quadruplex ion channel.
J.Am.Chem.Soc., 129, 2007