Author results

2GKI
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HEAVY AND LIGHT CHAIN VARIABLE SINGLE DOMAINS OF AN ANTI-DNA BINDING ANTIBODY HYDROLYZE BOTH DOUBLE- AND SINGLE-STRANDED DNAS WITHOUT SEQUENCE SPECIFICITY
Descriptor:nuclease
Authors:Kim, Y.R., Kim, J.S., Lee, S.H., Lee, W.R., Sohn, J.N., Chung, Y.C., Shim, H.K., Lee, S.C., Kwon, M.H., Kim, Y.S.
Deposit date:2006-04-02
Release date:2006-04-18
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.88 Å)
Cite:Heavy and light chain variable single domains of an anti-DNA binding antibody hydrolyze both double- and single-stranded DNAs without sequence specificity.
J.Biol.Chem., 281, 2006
2O5K
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CRYSTAL STRUCTURE OF GSK3BETA IN COMPLEX WITH A BENZOIMIDAZOL INHIBITOR
Descriptor:Glycogen synthase kinase-3 beta, 2-(2,4-DICHLORO-PHENYL)-7-HYDROXY-1H-BENZOIMIDAZOLE-4-CARBOXYLIC ACID [2-(4-METHANESULFONYLAMINO-PHENYL)-ETHYL]-AMIDE
Authors:Shin, D., Lee, S.C., Heo, Y.S., Cho, Y.S., Kim, Y.E., Hyun, Y.L., Cho, J.M., Lee, Y.S., Ro, S.
Deposit date:2006-12-06
Release date:2007-10-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Design and synthesis of 7-hydroxy-1H-benzoimidazole derivatives as novel inhibitors of glycogen synthase kinase-3beta
Bioorg.Med.Chem.Lett., 17, 2007
1WOU
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CRYSTAL STRUCTURE OF HUMAN TRP14
Descriptor:thioredoxin -related protein, 14 kDa
Authors:Woo, J.R., Kim, S.J., Jeong, W., Cho, Y.H., Lee, S.C., Chung, Y.J., Rhee, S.G., Ryu, S.E.
Deposit date:2004-08-25
Release date:2004-09-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis of cellular redox regulation by human TRP14
J.Biol.Chem., 279, 2004
4DIT
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CRYSTAL STRUCTURE OF GSK3BETA IN COMPLEX WITH A IMIDAZOPYRIDINE INHIBITOR
Descriptor:Glycogen synthase kinase-3 beta, N-(pyridin-3-yl)-2-(thiophen-3-yl)-3H-imidazo[4,5-b]pyridine-7-carboxamide
Authors:Kim, H.T., Lee, S.C., Chang, H.J.
Deposit date:2012-01-31
Release date:2012-02-15
Last modified:2012-02-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structure of GSK3beta in complex with a Imidazolopyridine inhibitor
To be Published
5VN7
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STRUCTURE OF BACTERIORHODOPSIN FROM CRYSTALS GROWN AT 20 DEG CELCIUS USING GLYNCOC15+4 AS AN LCP HOST LIPID
Descriptor:Bacteriorhodopsin
Authors:Ishchenko, A., Peng, L., Zinovev, E., Vlasov, A., Lee, S.C., Kuklin, A., Mishin, A., Borshchevskiy, V., Zhang, Q., Cherezov, V.
Deposit date:2017-04-28
Release date:2017-07-12
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Chemically Stable Lipids for Membrane Protein Crystallization.
Cryst Growth Des, 17, 2017
5VN9
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STRUCTURE OF BACTERIORHODOPSIN FROM CRYSTALS GROWN AT 4 DEG C USING GLYNCOC15+4 AS AN LCP HOST LIPID
Descriptor:Bacteriorhodopsin
Authors:Ishchenko, A., Peng, L., Zinovev, E., Vlasov, A., Lee, S.C., Kuklin, A., Mishin, A., Borshchevskiy, V., Zhang, Q., Cherezov, V.
Deposit date:2017-04-28
Release date:2017-07-12
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (2.594 Å)
Cite:Chemically Stable Lipids for Membrane Protein Crystallization.
Cryst Growth Des, 17, 2017
6BL6
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CRYSTALLIZATION OF LIPID A TRANSPORTER MSBA FROM SALMONELLA TYPHIMURIUM
Descriptor:Lipid A export ATP-binding/permease protein MsbA
Authors:Padayatti, P.S., Stanfield, R.L., Zhang, Q., Wilson, I.A., Lee, S.C.
Deposit date:2017-11-09
Release date:2019-01-09
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Insights into the Lipid A Transport Pathway in MsbA.
Structure, 27, 2019
6O30
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LIPID A TRANSPORTER MSBA FROM SALMONELLA TYPHIMURIUM
Descriptor:Lipid A export ATP-binding/permease protein MsbA
Authors:Padayatti, P.S., Zhang, Q., Wilson, I.A., Lee, S.C., Stanfield, R.L.
Deposit date:2019-02-25
Release date:2019-06-12
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (4.47 Å)
Cite:Structural Insights into the Lipid A Transport Pathway in MsbA.
Structure, 27, 2019
3RFJ
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DESIGN OF A BINDING SCAFFOLD BASED ON VARIABLE LYMPHOCYTE RECEPTORS OF JAWLESS VERTEBRATES BY MODULE ENGINEERING
Descriptor:Internalin B, repeat modules, Variable lymphocyte receptor, ...
Authors:Kim, H.J., Cheong, H.K., Jeon, Y.H.
Deposit date:2011-04-06
Release date:2012-03-14
Last modified:2017-08-16
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Design of a binding scaffold based on variable lymphocyte receptors of jawless vertebrates by module engineering
Proc.Natl.Acad.Sci.USA, 109, 2012
3RFS
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DESIGN OF A BINDING SCAFFOLD BASED ON VARIABLE LYMPHOCYTE RECEPTORS OF JAWLESS VERTEBRATES BY MODULE ENGINEERING
Descriptor:Internalin B, repeat modules, Variable lymphocyte receptor B, ...
Authors:Kim, H.J., Cheong, H.K., Jeon, Y.H.
Deposit date:2011-04-06
Release date:2012-03-14
Last modified:2017-08-16
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Design of a binding scaffold based on variable lymphocyte receptors of jawless vertebrates by module engineering
Proc.Natl.Acad.Sci.USA, 109, 2012
4HWL
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CRYSTAL STRUCTURE ANALYSIS OF THE BACTERIORHODOPSIN IN FACIAL AMPHIPHILE-7 DMPC BICELLE
Descriptor:Bacteriorhodopsin, RETINAL, HEXANE, ...
Authors:Lee, S., Stout, C.D., Zhang, Q.
Deposit date:2012-11-08
Release date:2013-03-20
Last modified:2013-05-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:Steroid-based facial amphiphiles for stabilization and crystallization of membrane proteins.
Proc.Natl.Acad.Sci.USA, 110, 2013
4HYX
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CRYSTAL STRUCTURE ANALYSIS OF THE BACTERIORHODOPSIN IN FACIAL AMPHIPHILE-4 DMPC BICELLE
Descriptor:Bacteriorhodopsin, RETINAL, N-OCTANE, ...
Authors:Lee, S., Stout, C.D., Zhang, Q.
Deposit date:2012-11-14
Release date:2013-03-20
Last modified:2013-05-22
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Steroid-based facial amphiphiles for stabilization and crystallization of membrane proteins.
Proc.Natl.Acad.Sci.USA, 110, 2013
4OM4
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CRYSTAL STRUCTURE OF CTX A2 FROM TAIWAN COBRA (NAJA NAJA ATRA)
Descriptor:Cytotoxin 2
Authors:Lin, C.C., Chang, C.I., Wu, W.G.
Deposit date:2014-01-26
Release date:2014-06-11
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.74 Å)
Cite:Endocytotic Routes of Cobra Cardiotoxins Depend on Spatial Distribution of Positively Charged and Hydrophobic Domains to Target Distinct Types of Sulfated Glycoconjugates on Cell Surface.
J.Biol.Chem., 289, 2014
4OM5
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CRYSTAL STRUCTURE OF CTX A4 FROM TAIWAN COBRA (NAJA NAJA ATRA)
Descriptor:Cytotoxin 4
Authors:Lin, C.C., Chang, C.I., Wu, W.G.
Deposit date:2014-01-26
Release date:2014-06-11
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Endocytotic Routes of Cobra Cardiotoxins Depend on Spatial Distribution of Positively Charged and Hydrophobic Domains to Target Distinct Types of Sulfated Glycoconjugates on Cell Surface.
J.Biol.Chem., 289, 2014
2NLU
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DOMAIN-SWAPPED DIMER OF THE PWWP MODULE OF HUMAN HEPATOMA-DERIVED GROWTH FACTOR
Descriptor:Hepatoma-derived growth factor
Authors:Sue, S.C., Lee, W.T., Huang, T.H.
Deposit date:2006-10-20
Release date:2007-09-04
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:PWWP module of human hepatoma-derived growth factor forms a domain-swapped dimer with much higher affinity for heparin
J.Mol.Biol., 367, 2007
5GWO
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CRYSTAL STRUCTURE OF RCAR3:PP2C S265F/I267M WITH (+)-ABA
Descriptor:Probable protein phosphatase 2C 50, ABA receptor RCAR3, MAGNESIUM ION, ...
Authors:Han, S., Lee, S.
Deposit date:2016-09-12
Release date:2017-09-13
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.816 Å)
Cite:Modulation of ABA Signaling by Altering VxG Phi L Motif of PP2Cs in Oryza sativa.
Mol Plant, 10, 2017
5GWP
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CRYSTAL STRUCTURE OF RCAR3:PP2C WILD-TYPE WITH (+)-ABA
Descriptor:Probable protein phosphatase 2C 50, ABA receptor RCAR3, MAGNESIUM ION, ...
Authors:Han, S., Lee, S.
Deposit date:2016-09-12
Release date:2017-09-13
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.577 Å)
Cite:Modulation of ABA Signaling by Altering VxG Phi L Motif of PP2Cs in Oryza sativa.
Mol Plant, 10, 2017
5GLJ
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CRYSTAL STRUCTURE OF PDZ1 DOMAIN OF HUMAN PROTEIN TYROSINE PHOSPHATASE PTP-BAS
Descriptor:Tyrosine-protein phosphatase non-receptor type 13, CHLORIDE ION
Authors:Lee, S.O., Ku, B., Chi, S.W.
Deposit date:2016-07-11
Release date:2016-11-23
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:High-resolution crystal structure of the PDZ1 domain of human protein tyrosine phosphatase PTP-Bas.
Biochem.Biophys.Res.Commun., 478, 2016
5GTJ
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CRYSTAL STRUCTURE OF CATALYTICALLY ACTIVE FORM OF HUMAN DUSP26
Descriptor:Dual specificity protein phosphatase 26, PHOSPHATE ION
Authors:Won, E.-Y., Kim, S.J., Chi, S.-W.
Deposit date:2016-08-21
Release date:2016-09-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Insight into the Critical Role of the N-Terminal Region in the Catalytic Activity of Dual-Specificity Phosphatase 26
Plos One, 11, 2016
6IWD
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THE PTP DOMAIN OF HUMAN PTPN14 IN A COMPLEX WITH THE CR3 DOMAIN OF HPV18 E7
Descriptor:Tyrosine-protein phosphatase non-receptor type 14, HPV18 E7, CHLORIDE ION, ...
Authors:Yun, H.-Y., Kim, S.J., Ku, B.
Deposit date:2018-12-05
Release date:2019-07-31
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for recognition of the tumor suppressor protein PTPN14 by the oncoprotein E7 of human papillomavirus.
Plos Biol., 17, 2019
5B8I
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CRYSTAL STRUCTURE OF CALCINEURIN A AND CALCINEURIN B IN COMPLEX WITH FKBP12 AND FK506 FROM COCCIDIOIDES IMMITIS RS
Descriptor:Serine/threonine-protein phosphatase, Calcineurin subunit B, variant, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID), Fox III, D., Dranow, D.M., Lorimer, D.D., Edwards, T.E.
Deposit date:2015-05-03
Release date:2015-05-20
Last modified:2019-11-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Harnessing calcineurin-FK506-FKBP12 crystal structures from invasive fungal pathogens to develop antifungal agents.
Nat Commun, 10, 2019
6TZ6
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CRYSTAL STRUCTURE OF CANDIDA ALBICANS CALCINEURIN A, CALCINEURIN B, FKBP12 AND FK506 (TACROLIMUS)
Descriptor:Serine/threonine-protein phosphatase, Calcineurin subunit B, FK506-binding protein 1, ...
Authors:Fox III, D., Lukacs, C.M.
Deposit date:2019-08-10
Release date:2019-09-18
Last modified:2019-10-02
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Harnessing calcineurin-FK506-FKBP12 crystal structures from invasive fungal pathogens to develop antifungal agents.
Nat Commun, 10, 2019
6TZ7
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CRYSTAL STRUCTURE OF ASPERGILLUS FUMIGATUS CALCINEURIN A, CALCINEURIN B, FKBP12 AND FK506 (TACROLIMUS)
Descriptor:Serine/threonine-protein phosphatase 2B catalytic subunit, Calcineurin Ca2+-binding regulatory subunit CnaB, FK506-binding protein 1A, ...
Authors:Fox III, D., Horanyi, P.S.
Deposit date:2019-08-10
Release date:2019-09-18
Last modified:2019-10-02
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Harnessing calcineurin-FK506-FKBP12 crystal structures from invasive fungal pathogens to develop antifungal agents.
Nat Commun, 10, 2019
6TZ8
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CRYSTAL STRUCTURE OF CRYPTOCOCCUS NEOFORMANS CALCEINEURIN A, CALCINEURIN B, AND FKBP12 WITH FK-506
Descriptor:Serine/threonine-protein phosphatase 2B catalytic subunit A1, Calcineurin subunit B, FK506-binding protein 1, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2019-08-10
Release date:2019-09-18
Last modified:2019-10-02
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Harnessing calcineurin-FK506-FKBP12 crystal structures from invasive fungal pathogens to develop antifungal agents.
Nat Commun, 10, 2019
3BD3
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CRYSTAL STRUCTURE OF SINGLE DOMAIN VL OF AN ANTI-DNA BINDING ANTIBODY 3D8 SCFV AND ITS ACTIVE SITE REVEALED BY COMPLEX STRUCTURES OF A SMALL MOLECULE AND METALS
Descriptor:catalytic antibody, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
Authors:Park, S.K., Kim, J.S.
Deposit date:2007-11-14
Release date:2008-04-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure of single-domain VL of an anti-DNA binding antibody 3D8 scFv and its active site revealed by complex structures of a small molecule and metals
Proteins, 71, 2008
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