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3U7K
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CRYSTAL STRUCTURES OF THE STAPHYLOCOCCUS AUREUS PEPTIDE DEFORMYLASE IN COMPLEX WITH TWO CLASSES OF NEW INHIBITORS
Descriptor:Peptide deformylase, (S)-N-(cyclopentylmethyl)-N-(2-(hydroxyamino)-2-oxoethyl)-2-(3-(2-methoxyphenyl)ureido)-3,3-dimethylbutanamide, ZINC ION
Authors:Lee, S.J., Lee, S.-J., Lee, S.K., Yoon, H.-J., Lee, H.H., Kim, K.K., Lee, B.J., Suh, S.W.
Deposit date:2011-10-14
Release date:2012-06-27
Last modified:2017-03-01
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structures of Staphylococcus aureus peptide deformylase in complex with two classes of new inhibitors
Acta Crystallogr.,Sect.D, 68, 2012
3U7L
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CRYSTAL STRUCTURES OF THE STAPHYLOCOCCUS AUREUS PEPTIDE DEFORMYLASE IN COMPLEX WITH TWO CLASSES OF NEW INHIBITORS
Descriptor:Peptide deformylase, ZINC ION, (S)-N-(cyclopentylmethyl)-2-(3-(3,5-difluorophenyl)ureido)-N-(2-(hydroxyamino)-2-oxoethyl)-3,3-dimethylbutanamide
Authors:Lee, S.J., Lee, S.-J., Lee, S.K., Yoon, H.-J., Lee, H.H., Kim, K.K., Lee, B.J., Suh, S.W.
Deposit date:2011-10-14
Release date:2012-06-27
Last modified:2017-03-01
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Structures of Staphylococcus aureus peptide deformylase in complex with two classes of new inhibitors
Acta Crystallogr.,Sect.D, 68, 2012
3U7M
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CRYSTAL STRUCTURES OF THE STAPHYLOCOCCUS AUREUS PEPTIDE DEFORMYLASE IN COMPLEX WITH TWO CLASSES OF NEW INHIBITORS
Descriptor:Peptide deformylase, ZINC ION, N-((2R,4S)-2-butyl-4-(3-(2-fluorophenyl)ureido)-5-methyl-3-oxohexyl)-N-hydroxyformamide
Authors:Lee, S.J., Lee, S.-J., Lee, S.K., Yoon, H.-J., Lee, H.H., Kim, K.K., Lee, B.J., Suh, S.W.
Deposit date:2011-10-14
Release date:2012-06-27
Last modified:2017-03-01
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structures of Staphylococcus aureus peptide deformylase in complex with two classes of new inhibitors
Acta Crystallogr.,Sect.D, 68, 2012
3U7N
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CRYSTAL STRUCTURES OF THE STAPHYLOCOCCUS AUREUS PEPTIDE DEFORMYLASE IN COMPLEX WITH TWO CLASSES OF NEW INHIBITORS
Descriptor:Peptide deformylase, ZINC ION, N-((2R,4S)-2-butyl-5-methyl-4-(3-(5-methylpyridin-2-yl)ureido)-3-oxohexyl)-N-hydroxyformamide
Authors:Lee, S.J., Lee, S.-J., Lee, S.K., Yoon, H.-J., Lee, H.H., Kim, K.K., Lee, B.J., Suh, S.W.
Deposit date:2011-10-14
Release date:2012-06-27
Last modified:2017-03-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structures of Staphylococcus aureus peptide deformylase in complex with two classes of new inhibitors
Acta Crystallogr.,Sect.D, 68, 2012
5KUK
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CRYSTAL STRUCTURE OF INWARD RECTIFIER KIR2.2 K62W MUTANT
Descriptor:ATP-sensitive inward rectifier potassium channel 12, POTASSIUM ION, DECYL-BETA-D-MALTOPYRANOSIDE
Authors:Lee, S.-J., Ren, F., Heyman, S., Yuan, P., Nichols, C.G.
Deposit date:2016-07-13
Release date:2016-08-10
Last modified:2016-09-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis of control of inward rectifier Kir2 channel gating by bulk anionic phospholipids.
J.Gen.Physiol., 148, 2016
5KUM
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CRYSTAL STRUCTURE OF INWARD RECTIFIER KIR2.2 K62W MUTANT IN COMPLEX WITH PIP2
Descriptor:ATP-sensitive inward rectifier potassium channel 12, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate, POTASSIUM ION, ...
Authors:Lee, S.-J., Ren, F., Heyman, S., Yuan, P., Nichols, C.G.
Deposit date:2016-07-13
Release date:2016-08-10
Last modified:2016-09-07
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis of control of inward rectifier Kir2 channel gating by bulk anionic phospholipids.
J.Gen.Physiol., 148, 2016
5WPL
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KRAS G12V, BOUND TO GPPNHP AND MINIPROTEIN 225-11
Descriptor:GTPase HRas, Ras-binding peptide, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Lee, S.-J., Shim, S.Y., McGee, J.H., Verdine, G.L.
Deposit date:2017-08-05
Release date:2018-01-03
Last modified:2018-03-14
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Exceptionally high-affinity Ras binders that remodel its effector domain.
J. Biol. Chem., 293, 2018
5WPM
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KRAS G12V, BOUND TO GPPNHP AND MINIPROTEIN 225-11(A30R)
Descriptor:GTPase KRas, Ras binding peptide, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Lee, S.-J., Shim, S.Y., McGee, J.H., Verdine, G.L.
Deposit date:2017-08-05
Release date:2018-01-03
Last modified:2018-03-14
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Exceptionally high-affinity Ras binders that remodel its effector domain.
J. Biol. Chem., 293, 2018
3CNK
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CRYSTAL STRUCTURE OF THE DIMERIZATION DOMAIN OF HUMAN FILAMIN A
Descriptor:Filamin-A, SULFATE ION
Authors:Lee, B.J., Seo, M.D., Seok, S.H., Lee, S.J., Kwon, A.R., Im, H.
Deposit date:2008-03-26
Release date:2009-02-10
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal structure of the dimerization domain of human filamin A
Proteins, 75, 2008
2VR5
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CRYSTAL STRUCTURE OF TREX FROM SULFOLOBUS SOLFATARICUS IN COMPLEX WITH ACARBOSE INTERMEDIATE AND GLUCOSE
Descriptor:GLYCOGEN OPERON PROTEIN GLGX, ALPHA-D-GLUCOSE, 4-O-(4,6-dideoxy-4-{[(1S,2S,3S,4R,5S)-2,3,4-trihydroxy-5-(hydroxymethyl)cyclohexyl]amino}-alpha-D-glucopyranosyl)-beta-D-glucopyranose, ...
Authors:Song, H.-N., Yoon, S.-M., Lee, S.-J., Cha, H.-J., Park, K.-H., Woo, E.-J.
Deposit date:2008-03-26
Release date:2008-07-29
Last modified:2015-04-01
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Insight Into the Bifunctional Mechanism of the Glycogen-Debranching Enzyme Trex from the Archaeon Sulfolobus Solfataricus.
J.Biol.Chem., 283, 2008
2W8N
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THE CRYSTAL STRUCTURE OF THE OXIDIZED FORM OF HUMAN SSADH
Descriptor:SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL, SULFATE ION
Authors:Kim, Y.-G., Kim, K.-J.
Deposit date:2009-01-19
Release date:2009-06-09
Last modified:2013-04-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Redox-Switch Modulation of Human Ssadh by Dynamic Catalytic Loop.
Embo J., 28, 2009
2W8O
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THE CRYSTAL STRUCTURE OF THE REDUCED FORM OF HUMAN SSADH
Descriptor:SUCCINIC SEMIALDEHYDE DEHYDROGENASE MITOCHONDRIAL, SULFATE ION, GLYCEROL
Authors:Kim, Y.-G., Kim, K.-J.
Deposit date:2009-01-19
Release date:2009-06-09
Last modified:2013-08-07
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Redox-Switch Modulation of Human Ssadh by Dynamic Catalytic Loop.
Embo J., 28, 2009
2W8P
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THE CRYSTAL STRUCTURE OF HUMAN C340A SSADH
Descriptor:SUCCINIC SEMIALDEHYDE DEHYDROGENASE MITOCHONDRIAL, SULFATE ION, GLYCEROL
Authors:Kim, Y.-G., Kim, K.-J.
Deposit date:2009-01-19
Release date:2009-06-09
Last modified:2013-08-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Redox-Switch Modulation of Human Ssadh by Dynamic Catalytic Loop.
Embo J., 28, 2009
2W8Q
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THE CRYSTAL STRUCTURE OF HUMAN SSADH IN COMPLEX WITH SSA.
Descriptor:SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL, SULFATE ION, ...
Authors:Kim, Y.-G., Kim, K.-J.
Deposit date:2009-01-19
Release date:2009-06-09
Last modified:2013-08-07
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Redox-Switch Modulation of Human Ssadh by Dynamic Catalytic Loop.
Embo J., 28, 2009
2W8R
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THE CRYSTAL STRUCTURE OF HUMAN SSADH IN COMPLEX WITH NAD+
Descriptor:SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Kim, Y.-G., Kim, K.-J.
Deposit date:2009-01-19
Release date:2009-06-09
Last modified:2013-08-07
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Redox-Switch Modulation of Human Ssadh by Dynamic Catalytic Loop.
Embo J., 28, 2009
3ENM
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THE STRUCTURE OF THE MAP2K MEK6 REVEALS AN AUTOINHIBITORY DIMER
Descriptor:Dual specificity mitogen-activated protein kinase kinase 6, SULFATE ION, GLYCEROL, ...
Authors:Min, X., Akella, R., He, H., Humphreys, J.M., Tsutakawa, S., Lee, S.-J., Tainer, J.A., Cobb, M.H., Goldsmith, E.J.
Deposit date:2008-09-25
Release date:2009-03-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:The structure of the MAP2K MEK6 reveals an autoinhibitory dimer
Structure, 17, 2009
3QPH
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THE THREE-DIMENSIONAL STRUCTURE OF TRMB, A GLOBAL TRANSCRIPTIONAL REGULATOR OF THE HYPERTHERMOPHILIC ARCHAEON PYROCOCCUS FURIOSUS IN COMPLEX WITH SUCROSE
Descriptor:TrmB, a global transcription regulator, ACETATE ION, ...
Authors:Krug, M., Lee, S.-J., Boos, W., Welte, W., Diederichs, K.
Deposit date:2011-02-13
Release date:2012-05-30
Last modified:2013-08-28
Method:X-RAY DIFFRACTION (2.992 Å)
Cite:The three-dimensional structure of TrmB, a transcriptional regulator of dual function in the hyperthermophilic archaeon Pyrococcus furiosus in complex with sucrose.
Protein Sci., 22, 2013
4TUT
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STRUCTURE OF A PRION PEPTIDE
Descriptor:Prion peptide: GLY-GLY-TYR-MET-LEU-GLY
Authors:Yu, L., Lee, S.-J., Yee, V.
Deposit date:2014-06-24
Release date:2015-05-27
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (0.9 Å)
Cite:Crystal Structures of Polymorphic Prion Protein beta 1 Peptides Reveal Variable Steric Zipper Conformations.
Biochemistry, 54, 2015
4UBY
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CRYSTAL STRUCTURE OF A POLYMORPHIC BETA1 PEPTIDE
Descriptor:prion peptide
Authors:Yu, L., Lee, S.-J., Yee, V.
Deposit date:2014-08-13
Release date:2015-05-27
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1 Å)
Cite:Crystal Structures of Polymorphic Prion Protein beta 1 Peptides Reveal Variable Steric Zipper Conformations.
Biochemistry, 54, 2015
4UBZ
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CRYSTAL STRUCTURE OF A PRION PEPTIDE
Descriptor:prion peptide, SODIUM ION
Authors:Yu, L., Lee, S.-J., Yee, V.
Deposit date:2014-08-13
Release date:2015-05-27
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.001 Å)
Cite:Crystal Structures of Polymorphic Prion Protein beta 1 Peptides Reveal Variable Steric Zipper Conformations.
Biochemistry, 54, 2015
4W5L
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CRYSTAL STRUCTURE OF A PRP PEPTIDE
Descriptor:PrP peptide
Authors:Yu, L., Lee, S.-J., Yee, V.
Deposit date:2014-08-18
Release date:2015-05-27
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1 Å)
Cite:Crystal Structures of Polymorphic Prion Protein beta 1 Peptides Reveal Variable Steric Zipper Conformations.
Biochemistry, 54, 2015
4W5M
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PRP PEPTIDE
Descriptor:PrP peptide, (4S)-2-METHYL-2,4-PENTANEDIOL
Authors:Yu, L., Lee, S.-J., Yee, V.
Deposit date:2014-08-18
Release date:2015-05-27
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Crystal Structures of Polymorphic Prion Protein beta 1 Peptides Reveal Variable Steric Zipper Conformations.
Biochemistry, 54, 2015
4W5P
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PRP PEPTIDE
Descriptor:PrP peptide, (4S)-2-METHYL-2,4-PENTANEDIOL
Authors:Yu, L., Lee, S.-J., Yee, V.
Deposit date:2014-08-18
Release date:2015-05-27
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.151 Å)
Cite:Crystal Structures of Polymorphic Prion Protein beta 1 Peptides Reveal Variable Steric Zipper Conformations.
Biochemistry, 54, 2015
4W5Y
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CRYSTAL STRUCTURE OF PRP PEPTTIDE
Descriptor:Prp peptide
Authors:Yu, L., Lee, S.-J., Yee, V.
Deposit date:2014-08-19
Release date:2015-05-27
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.122 Å)
Cite:Crystal Structures of Polymorphic Prion Protein beta 1 Peptides Reveal Variable Steric Zipper Conformations.
Biochemistry, 54, 2015
4W67
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CRYSTAL STRUCTURE OF PRP PEPTIDE
Descriptor:PrP peptide
Authors:Yu, L., Lee, S.-J., Yee, V.
Deposit date:2014-08-20
Release date:2015-05-27
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.001 Å)
Cite:Crystal Structures of Polymorphic Prion Protein beta 1 Peptides Reveal Variable Steric Zipper Conformations.
Biochemistry, 54, 2015
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