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4Q0F
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CRYSTAL STRUCTURE OF THERMOTOGA MARITIMA FTSH PERIPLASMIC DOMAIN
Descriptor:ATP-dependent zinc metalloprotease FtsH
Authors:An, J.Y., Sharif, H., Barrera, F.N., Karabadzhak, A., Kang, G.B., Park, K.J., Sakkiah, S., Lee, K.W., Lee, S., Engelman, D.M., Wang, J., Eom, S.H.
Deposit date:2014-04-01
Release date:2015-04-01
Method:X-RAY DIFFRACTION (1.948 Å)
Cite:Structures of periplasmic and transmembrane domains of FtsH suggest a reverse translocon mechanism for protein extraction from membrane
To be Published
4O6W
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PEPTIDE-BASED INHIBITORS OF PLK1 POLO-BOX DOMAIN
Descriptor:Serine/threonine-protein kinase PLK1, Peptide-Based inhibitor
Authors:Qian, W.-J., Park, J.-E., Lim, D.C., Park, S.-Y., Lee, K.-W., Yaffe, M.B., Lee, K.S., Burke, T.R.
Deposit date:2013-12-23
Release date:2014-12-03
Method:X-RAY DIFFRACTION (1.448 Å)
Cite:Mono-anionic phosphopeptides produced by unexpected histidine alkylation exhibit high plk1 polo-box domain-binding affinities and enhanced antiproliferative effects in hela cells.
Biopolymers, 102, 2014
4N9J
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CRYSTAL STRUCTURE OF THE CRYPTIC POLO BOX DOMAIN OF HUMAN PLK4
Descriptor:Serine/threonine-protein kinase PLK4, CHLORIDE ION, SULFATE ION
Authors:Ku, B., Kim, J.H., Lee, K.S., Kim, S.J.
Deposit date:2013-10-21
Release date:2014-07-02
Last modified:2014-08-20
Method:X-RAY DIFFRACTION (2.601 Å)
Cite:Molecular basis for unidirectional scaffold switching of human Plk4 in centriole biogenesis.
Nat.Struct.Mol.Biol., 21, 2014
4N7Z
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CRYSTAL STRUCTURE OF HUMAN PLK4 CRYPTIC POLO BOX (CPB) IN COMPLEX WITH A CEP192 N-TERMINAL FRAGMENT
Descriptor:Serine/threonine-protein kinase PLK4, Centrosomal protein of 192 kDa
Authors:Park, S.-Y., Park, J.-E., Tian, L., Kim, T.-S., Yang, W., Lee, K.S.
Deposit date:2013-10-16
Release date:2014-07-02
Last modified:2014-08-20
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Molecular basis for unidirectional scaffold switching of human Plk4 in centriole biogenesis.
Nat.Struct.Mol.Biol., 21, 2014
4N7V
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CRYSTAL STRUCTURE OF HUMAN PLK4 CRYPTIC POLO BOX (CPB) IN COMPLEX WITH A CEP152 N-TERMINAL FRAGMENT
Descriptor:Serine/threonine-protein kinase PLK4, Centrosomal protein of 152 kDa
Authors:Park, S.-Y., Park, J.-E., Tian, L., Kim, T.-S., Yang, W., Lee, K.S.
Deposit date:2013-10-16
Release date:2014-07-02
Last modified:2014-08-20
Method:X-RAY DIFFRACTION (2.758 Å)
Cite:Molecular basis for unidirectional scaffold switching of human Plk4 in centriole biogenesis.
Nat.Struct.Mol.Biol., 21, 2014
4M8A
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CRYSTAL STRUCTURE OF THERMOTOGA MARITIMA FTSH PERIPLASMIC DOMAIN
Descriptor:ATP-dependent zinc metalloprotease FtsH, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
Authors:An, J.Y., Sharif, H., Barrera, F.N., Karabadzhak, A., Kang, G.B., Park, K.J., Sakkiah, S., Lee, K.W., Lee, S., Engelman, D.M., Wang, J., Eom, S.H.
Deposit date:2013-08-13
Release date:2014-09-17
Method:X-RAY DIFFRACTION (1.502 Å)
Cite:Structural roles of periplasmic and transmembrane domains of FtsH in ATP-dependent proteolysis
To be Published
4HRH
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CRYSTAL STRUCTURE OF P11-ANNEXIN A2(N-TERMINAL) FUSION PROTEIN IN COMPLEX WITH SMARCA3 PEPTIDE
Descriptor:Protein S100-A10, Annexin A2, Helicase-like transcription factor, ...
Authors:Gao, P., Patel, D.J.
Deposit date:2012-10-27
Release date:2013-03-06
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (3.001 Å)
Cite:SMARCA3, a Chromatin-Remodeling Factor, Is Required for p11-Dependent Antidepressant Action.
Cell(Cambridge,Mass.), 152, 2013
4HRG
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CRYSTAL STRUCTURE OF P11-ANNEXIN A2(N-TERMINAL) FUSION PROTEIN IN COMPLEX WITH AHNAK1 PEPTIDE
Descriptor:Protein S100-A10, Neuroblast differentiation-associated protein AHNAK
Authors:Gao, P., Patel, D.J.
Deposit date:2012-10-27
Release date:2013-03-06
Method:X-RAY DIFFRACTION (2.0001 Å)
Cite:SMARCA3, a Chromatin-Remodeling Factor, Is Required for p11-Dependent Antidepressant Action.
Cell(Cambridge,Mass.), 152, 2013
4HRE
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CRYSTAL STRUCTURE OF P11/ANNEXIN A2 HETEROTETRAMER IN COMPLEX WITH SMARCA3 PEPTIDE
Descriptor:Annexin A2, Protein S100-A10, Helicase-like transcription factor
Authors:Gao, P., Patel, D.J.
Deposit date:2012-10-27
Release date:2013-03-06
Method:X-RAY DIFFRACTION (2.7852 Å)
Cite:SMARCA3, a Chromatin-Remodeling Factor, Is Required for p11-Dependent Antidepressant Action.
Cell(Cambridge,Mass.), 152, 2013
3V3V
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STRUCTURAL AND FUNCTIONAL ANALYSIS OF QUERCETAGETIN, A NATURAL JNK1 INHIBITOR
Descriptor:Mitogen-activated protein kinase 8, C-Jun-amino-terminal kinase-interacting protein 1, 3,5,6,7-TETRAHYDROXY-2-(3,4-DIHYDROXYPHENYL)-4H-CHROMEN-4-ONE, ...
Authors:Baek, S., Kang, N.J., Popowicz, G.M., Arciniega, M., Jung, S.K., Byun, S., Song, N.R., Heo, Y.S., Kim, B.Y., Lee, H.J., Holak, T.A., Augustin, M., Bode, A.M., Huber, R., Dong, Z., Lee, K.W.
Deposit date:2011-12-14
Release date:2012-12-05
Last modified:2013-01-30
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural and Functional Analysis of the Natural JNK1 Inhibitor Quercetagetin.
J.Mol.Biol., 425, 2013
3V3B
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STRUCTURE OF THE STAPLED P53 PEPTIDE BOUND TO MDM2
Descriptor:E3 ubiquitin-protein ligase Mdm2, SAH-p53-8 stapled-peptide, CHLORIDE ION
Authors:Baek, S., Kutchukian, P.S., Verdine, G.L., Huber, R., Holak, T.A., Ki Won, L., Popowicz, G.M.
Deposit date:2011-12-13
Release date:2012-01-18
Last modified:2013-11-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the stapled p53 peptide bound to Mdm2.
J.Am.Chem.Soc., 134, 2012
1XR0
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STRUCTURAL BASIS OF SNT PTB DOMAIN INTERACTIONS WITH DISTINCT NEUROTROPHIC RECEPTORS
Descriptor:Basic fibroblast growth factor receptor 1, FGFR signalling adaptor SNT-1
Authors:Dhalluin, C., Yan, K.S., Plotnikova, O., Lee, K.W., Zeng, L., Kuti, M., Mujtaba, S., Goldfarb, M.P., Zhou, M.-M.
Deposit date:2004-10-13
Release date:2004-11-02
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural Basis of SNT PTB Domain Interactions with Distinct Neurotrophic Receptors
Mol.Cell, 6, 2000
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