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1Y6Q
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BU of 1y6q by Molmil
Cyrstal structure of MTA/AdoHcy nucleosidase complexed with MT-DADMe-ImmA
Descriptor: (3R,4S)-1-[(4-AMINO-5H-PYRROLO[3,2-D]PYRIMIDIN-7-YL)METHYL]-4-[(METHYLSULFANYL)METHYL]PYRROLIDIN-3-OL, CHLORIDE ION, MTA/SAH nucleosidase
Authors:Lee, J.E, Singh, V, Evans, G.B, Tyler, P.C, Furneaux, R.H, Cornell, K.A, Riscoe, M.K, Schramm, V.L, Howell, P.L.
Deposit date:2004-12-06
Release date:2005-03-01
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural rationale for the affinity of pico- and femtomolar transition state analogues of Escherichia coli 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase.
J.Biol.Chem., 280, 2005
1Y6R
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BU of 1y6r by Molmil
Crystal structure of MTA/AdoHcy nucleosidase complexed with MT-ImmA.
Descriptor: (3S,4R)-2-(4-AMINO-5H-PYRROLO[3,2-D]PYRIMIDIN-7-YL)-5-[(METHYLSULFANYL)METHYL]PYRROLIDINE-3,4-DIOL, MTA/SAH nucleosidase
Authors:Lee, J.E, Singh, V, Evans, G.B, Tyler, P.C, Furneaux, R.H, Cornell, K.A, Riscoe, M.K, Schramm, V.L, Howell, P.L.
Deposit date:2004-12-06
Release date:2005-03-01
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural rationale for the affinity of pico- and femtomolar transition state analogues of Escherichia coli 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase.
J.Biol.Chem., 280, 2005
3INU
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BU of 3inu by Molmil
Crystal structure of an unbound KZ52 neutralizing anti-Ebolavirus antibody.
Descriptor: GLYCEROL, KZ52 antibody fragment heavy chain, KZ52 antibody fragment light chain, ...
Authors:Lee, J.E, Fusco, M.L, Abelson, D.M, Hessell, A.J, Burton, D.R, Saphire, E.O.
Deposit date:2009-08-12
Release date:2009-10-27
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Techniques and tactics used in determining the structure of the trimeric ebolavirus glycoprotein.
Acta Crystallogr.,Sect.D, 65, 2009
1NC3
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BU of 1nc3 by Molmil
Crystal structure of E. coli MTA/AdoHcy nucleosidase complexed with formycin A (FMA)
Descriptor: (1S)-1-(7-amino-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-1,4-anhydro-D-ribitol, MTA/SAH nucleosidase
Authors:Lee, J.E, Cornell, K.A, Riscoe, M.K, Howell, P.L.
Deposit date:2002-12-04
Release date:2003-03-25
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of Escherichia coli 5'-methylthioadenosine/ S-adenosylhomocysteine nucleosidase inhibitor complexes provide insight into the conformational changes required for substrate binding and catalysis.
J.Biol.Chem., 278, 2003
1NC1
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BU of 1nc1 by Molmil
Crystal structure of E. coli MTA/AdoHcy nucleosidase complexed with 5'-methylthiotubercidin (MTH)
Descriptor: 2-(4-AMINO-PYRROLO[2,3-D]PYRIMIDIN-7-YL)-5-METHYLSULFANYLMETHYL-TETRAHYDRO-FURAN-3,4-DIOL, MTA/SAH nucleosidase
Authors:Lee, J.E, Cornell, K.A, Riscoe, M.K, Howell, P.L.
Deposit date:2002-12-04
Release date:2003-11-25
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of Escherichia coli 5'-methylthioadenosine/ S-adenosylhomocysteine nucleosidase inhibitor complexes provide insight into the conformational changes required for substrate binding and catalysis.
J.Biol.Chem., 278, 2003
3CSY
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BU of 3csy by Molmil
Crystal structure of the trimeric prefusion Ebola virus glycoprotein in complex with a neutralizing antibody from a human survivor
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein GP1, ...
Authors:Lee, J.E, Fusco, M.L, Hessell, A.J, Oswald, W.B, Burton, D.R, Saphire, E.O.
Deposit date:2008-04-10
Release date:2008-07-08
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structure of the Ebola virus glycoprotein bound to an antibody from a human survivor.
Nature, 454, 2008
1JYS
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BU of 1jys by Molmil
Crystal Structure of E. coli MTA/AdoHcy Nucleosidase
Descriptor: ADENINE, MTA/SAH nucleosidase
Authors:Lee, J.E, Cornell, K.A, Riscoe, M.K, Howell, P.L.
Deposit date:2001-09-13
Release date:2002-10-01
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of E. coli 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase reveals similarity to the purine nucleoside phosphorylases.
Structure, 9, 2001
1SD2
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BU of 1sd2 by Molmil
STRUCTURE OF HUMAN 5'-DEOXY-5'-METHYLTHIOADENOSINE PHOSPHORYLASE COMPLEXED WITH 5'-METHYLTHIOTUBERCIDIN
Descriptor: 2-(4-AMINO-PYRROLO[2,3-D]PYRIMIDIN-7-YL)-5-METHYLSULFANYLMETHYL-TETRAHYDRO-FURAN-3,4-DIOL, 5'-methylthioadenosine phosphorylase, SULFATE ION
Authors:Lee, J.E, Settembre, E.C, Cornell, K.A, Riscoe, M.K, Sufrin, J.R, Ealick, S.E, Howell, P.L.
Deposit date:2004-02-12
Release date:2004-05-18
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Comparison of MTA Phosphorylase and MTA/AdoHcy Nucleosidase Explains Substrate Preferences and Identifies Regions Exploitable for Inhibitor Design.
Biochemistry, 43, 2004
1SD1
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BU of 1sd1 by Molmil
STRUCTURE OF HUMAN 5'-DEOXY-5'-METHYLTHIOADENOSINE PHOSPHORYLASE COMPLEXED WITH FORMYCIN A
Descriptor: (1S)-1-(7-amino-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-1,4-anhydro-D-ribitol, 5'-methylthioadenosine phosphorylase
Authors:Lee, J.E, Settembre, E.C, Cornell, K.A, Riscoe, M.K, Sufrin, J.R, Ealick, S.E, Howell, P.L.
Deposit date:2004-02-12
Release date:2004-05-18
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Structural Comparison of MTA Phosphorylase and MTA/AdoHcy Nucleosidase Explains Substrate Preferences and Identifies Regions Exploitable for Inhibitor Design.
Biochemistry, 43, 2004
1Z5O
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BU of 1z5o by Molmil
Crystal structure of MTA/AdoHcy nucleosidase Asp197Asn mutant complexed with 5'-methylthioadenosine
Descriptor: 5'-DEOXY-5'-METHYLTHIOADENOSINE, MTA/SAH nucleosidase
Authors:Lee, J.E, Smith, G.D, Horvatin, C, Huang, D.J.T, Cornell, K.A, Riscoe, M.K, Howell, P.L.
Deposit date:2005-03-18
Release date:2005-10-04
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural snapshots of MTA/AdoHcy nucleosidase along the reaction coordinate provide insights into enzyme and nucleoside flexibility during catalysis
J.Mol.Biol., 352, 2005
1Z5P
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BU of 1z5p by Molmil
Crystal structure of MTA/AdoHcy nucleosidase with a ligand-free purine binding site
Descriptor: 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, GLYCEROL, ISOPROPYL ALCOHOL, ...
Authors:Lee, J.E, Smith, G.D, Horvatin, C, Huang, D.J.T, Cornell, K.A, Riscoe, M.K, Howell, P.L.
Deposit date:2005-03-18
Release date:2005-10-04
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural snapshots of MTA/AdoHcy nucleosidase along the reaction coordinate provide insights into enzyme and nucleoside flexibility during catalysis
J.Mol.Biol., 352, 2005
1Z5N
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BU of 1z5n by Molmil
Crystal structure of MTA/AdoHcy nucleosidase Glu12Gln mutant complexed with 5-methylthioribose and adenine
Descriptor: 5-S-methyl-5-thio-alpha-D-ribofuranose, ADENINE, MTA/SAH nucleosidase
Authors:Lee, J.E, Smith, G.D, Horvatin, C, Huang, D.J.T, Cornell, K.A, Riscoe, M.K, Howell, P.L.
Deposit date:2005-03-18
Release date:2005-10-04
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural snapshots of MTA/AdoHcy nucleosidase along the reaction coordinate provide insights into enzyme and nucleoside flexibility during catalysis
J.Mol.Biol., 352, 2005
2QHR
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BU of 2qhr by Molmil
Crystal structure of the 13F6-1-2 Fab fragment bound to its Ebola virus glycoprotein peptide epitope.
Descriptor: 13F6-1-2 Fab fragment V lambda x light chain, 13F6-1-2 Fab fragment heavy chain, Envelope glycoprotein peptide
Authors:Lee, J.E, Kuehne, A, Abelson, D.M, Fusco, M.L, Hart, M.K, Saphire, E.O.
Deposit date:2007-07-02
Release date:2008-01-22
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Complex of a protective antibody with its Ebola virus GP peptide epitope: unusual features of a V lambda x light chain.
J.Mol.Biol., 375, 2008
2GMK
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BU of 2gmk by Molmil
Crystal structure of onconase double mutant with spontaneously-assembled (AMP) 4 stack
Descriptor: ADENOSINE MONOPHOSPHATE, P-30 protein
Authors:Bae, E, Lee, J.E, Raines, R.T, Wesenberg, G.E, Phillips Jr, G.N, Bitto, E, Bingman, C.A, Center for Eukaryotic Structural Genomics (CESG)
Deposit date:2006-04-06
Release date:2006-04-25
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural basis for catalysis by onconase.
J.Mol.Biol., 375, 2008
2I5S
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BU of 2i5s by Molmil
Crystal structure of onconase with bound nucleic acid
Descriptor: 5'-D(*A*(DU)P*GP*A)-3', P-30 protein
Authors:Bae, E, Lee, J.E, Raines, R.T, Wesenberg, G.E, Phillips Jr, G.N, Bitto, E, Bingman, C.A, Center for Eukaryotic Structural Genomics (CESG)
Deposit date:2006-08-25
Release date:2006-09-05
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for catalysis by onconase.
J.Mol.Biol., 375, 2008
7UJV
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BU of 7ujv by Molmil
Structure of PHD2 in complex with HIF2a-CODD
Descriptor: Egl nine homolog 1, Endothelial PAS domain-containing protein 1, FE (III) ION, ...
Authors:Ferens, F.G, Tarade, D, Lee, J.E, Ohh, M.
Deposit date:2022-03-31
Release date:2023-04-05
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Deficiency in PHD2-mediated hydroxylation of HIF2 alpha underlies Pacak-Zhuang syndrome.
Commun Biol, 7, 2024
7TA2
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BU of 7ta2 by Molmil
Crystal structure of the human sperm-expressed surface protein SPACA6
Descriptor: BROMIDE ION, Sperm acrosome membrane-associated protein 6
Authors:Vance, T.D.R, Yip, P, Jimenez, E, Uson, I, Lee, J.E.
Deposit date:2021-12-20
Release date:2022-08-31
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:SPACA6 ectodomain structure reveals a conserved superfamily of gamete fusion-associated proteins.
Commun Biol, 5, 2022
4XYP
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BU of 4xyp by Molmil
Crystal structure of a piscine viral fusion protein
Descriptor: 3,7-BIS(DIMETHYLAMINO)PHENOTHIAZIN-5-IUM, CHLORIDE ION, Fusion protein
Authors:Cook, J.D, Lee, J.E.
Deposit date:2015-02-02
Release date:2015-06-24
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Electrostatic Architecture of the Infectious Salmon Anemia Virus (ISAV) Core Fusion Protein Illustrates a Carboxyl-Carboxylate pH Sensor.
J.Biol.Chem., 290, 2015
5UQY
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BU of 5uqy by Molmil
Crystal structure of Marburg virus GP in complex with the human survivor antibody MR78
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ENVELOPE GLYCOPROTEIN GP1, ...
Authors:Hashiguchi, T, Fusco, M.L, Hastie, K.M, Bomholdt, Z.A, Lee, J.E, Flyak, A.I, Matsuoka, R, Kohda, D, Yanagi, Y, Hammel, M, Crowe, J.E, Saphire, E.O.
Deposit date:2017-02-08
Release date:2017-03-01
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Structural basis for Marburg virus neutralization by a cross-reactive human antibody.
Cell, 160, 2015
6BVB
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BU of 6bvb by Molmil
Crystal structure of HIF-2alpha-pVHL-elongin B-elongin C
Descriptor: Elongin-B, Elongin-C, Hypoxia-Inducible Factor 2 alpha, ...
Authors:Tarade, D, Ohh, M, Lee, J.E.
Deposit date:2017-12-12
Release date:2018-08-01
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.002 Å)
Cite:HIF-2 alpha-pVHL complex reveals broad genotype-phenotype correlations in HIF-2 alpha-driven disease.
Nat Commun, 9, 2018
6WKO
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BU of 6wko by Molmil
Structure of an influenza C virus hemagglutinin-esterase-fusion (HEF2) intermediate
Descriptor: CHLORIDE ION, Hemagglutinin-esterase-fusion glycoprotein
Authors:Serrao, V.H.B, Lee, J.E.
Deposit date:2020-04-16
Release date:2021-05-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.401 Å)
Cite:Snapshot of an influenza virus glycoprotein fusion intermediate.
Cell Rep, 35, 2021
3BL6
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BU of 3bl6 by Molmil
Crystal structure of Staphylococcus aureus 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase in complex with formycin A
Descriptor: (1S)-1-(7-amino-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-1,4-anhydro-D-ribitol, 5'-methylthioadenosine nucleosidase/S-adenosylhomocysteine nucleosidase
Authors:Siu, K.K.W, Lee, J.E, Smith, G.D, Horvatin, C, Howell, P.L.
Deposit date:2007-12-10
Release date:2008-06-10
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of Staphylococcus aureus 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase
Acta Crystallogr.,Sect.F, 64, 2008
7S94
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BU of 7s94 by Molmil
Structure of the core postfusion porcine endogenous retrovirus fusion protein
Descriptor: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, Endogenous retrovirus group S71 member 1 Env polyprotein
Authors:Dean, T.T, Lee, J.E.
Deposit date:2021-09-20
Release date:2022-01-12
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the Core Postfusion Porcine Endogenous Retrovirus Fusion Protein.
Mbio, 13, 2022
1JDI
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BU of 1jdi by Molmil
CRYSTAL STRUCTURE OF L-RIBULOSE-5-PHOSPHATE 4-EPIMERASE
Descriptor: L-RIBULOSE 5 PHOSPHATE 4-EPIMERASE, ZINC ION
Authors:Luo, Y, Samuel, J, Mosimann, S.C, Lee, J.E, Tanner, M.E, Strynadka, N.C.J.
Deposit date:2001-06-13
Release date:2002-01-23
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The structure of L-ribulose-5-phosphate 4-epimerase: an aldolase-like platform for epimerization.
Biochemistry, 40, 2001
1K0W
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BU of 1k0w by Molmil
CRYSTAL STRUCTURE OF L-RIBULOSE-5-PHOSPHATE 4-EPIMERASE
Descriptor: L-RIBULOSE 5 PHOSPHATE 4-EPIMERASE, ZINC ION
Authors:Luo, Y, Samuel, J, Mosimann, S.C, Lee, J.E, Strynadka, N.C.J.
Deposit date:2001-09-21
Release date:2003-01-28
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The structure of L-ribulose-5-phosphate 4-epimerase: an aldolase-like platform for epimerization
Biochemistry, 40, 2001

 

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