Author results

1EGD
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STRUCTURE OF T255E, E376G MUTANT OF HUMAN MEDIUM CHAIN ACYL-COA DEHYDROGENASE
Descriptor:MEDIUM CHAIN ACYL-COA DEHYDROGENASE, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Lee, H.J., Wang, M., Paschke, R., Nandy, A., Ghisla, S., Kim, J.P.
Deposit date:1996-04-11
Release date:1997-06-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structures of the wild type and the Glu376Gly/Thr255Glu mutant of human medium-chain acyl-CoA dehydrogenase: influence of the location of the catalytic base on substrate specificity.
Biochemistry, 35, 1996
1EGE
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STRUCTURE OF T255E, E376G MUTANT OF HUMAN MEDIUM CHAIN ACYL-COA DEHYDROGENASE
Descriptor:MEDIUM CHAIN ACYL-COA DEHYDROGENASE, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Lee, H.J., Wang, M., Paschke, R., Nandy, A., Ghisla, S., Kim, J.P.
Deposit date:1996-04-11
Release date:1997-06-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Crystal structures of the wild type and the Glu376Gly/Thr255Glu mutant of human medium-chain acyl-CoA dehydrogenase: influence of the location of the catalytic base on substrate specificity.
Biochemistry, 35, 1996
1EGC
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STRUCTURE OF T255E, E376G MUTANT OF HUMAN MEDIUM CHAIN ACYL-COA DEHYDROGENASE COMPLEXED WITH OCTANOYL-COA
Descriptor:MEDIUM CHAIN ACYL-COA DEHYDROGENASE, OCTANOYL-COENZYME A, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Lee, H.J., Wang, M., Paschke, R., Nandy, A., Ghisla, S., Kim, J.P.
Deposit date:1996-04-11
Release date:1997-11-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structures of the wild type and the Glu376Gly/Thr255Glu mutant of human medium-chain acyl-CoA dehydrogenase: influence of the location of the catalytic base on substrate specificity.
Biochemistry, 35, 1996
1DCS
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DEACETOXYCEPHALOSPORIN C SYNTHASE FROM S. CLAVULIGERUS
Descriptor:DEACETOXYCEPHALOSPORIN C SYNTHASE, SULFATE ION
Authors:Valegard, K., Terwisscha Van Scheltinga, A.C., Lloyd, M.D., Hara, T., Ramaswamy, S., Perrakis, A., Thompson, A., Lee, H.J., Baldwin, J.E., Schofield, C.J., Hajdu, J., Andersson, I.
Deposit date:1998-06-05
Release date:1999-06-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structure of a cephalosporin synthase.
Nature, 394, 1998
1RXF
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DEACETOXYCEPHALOSPORIN C SYNTHASE COMPLEXED WITH FE(II)
Descriptor:DEACETOXYCEPHALOSPORIN C SYNTHASE, FE (III) ION
Authors:Valegard, K., Terwisscha Van Scheltinga, A.C., Lloyd, M.D., Hara, T., Ramaswamy, S., Perrakis, A., Thompson, A., Lee, H.J., Baldwin, J.E., Schofield, C.J., Hajdu, J., Andersson, I.
Deposit date:1998-06-05
Release date:1999-06-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structure of a cephalosporin synthase.
Nature, 394, 1998
1RXG
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DEACETOXYCEPHALOSPORIN C SYNTHASE COMPLEXED WITH FE(II) AND 2-OXOGLUTARATE
Descriptor:DEACETOXYCEPHALOSPORIN C SYNTHASE, FE (III) ION, SULFATE ION, ...
Authors:Valegard, K., Terwisscha Van Scheltinga, A.C., Lloyd, M.D., Hara, T., Ramaswamy, S., Perrakis, A., Thompson, A., Lee, H.J., Baldwin, J.E., Shofield, C.J., Hajdu, J., Andersson, I.
Deposit date:1998-06-05
Release date:1999-06-08
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structure of a cephalosporin synthase.
Nature, 394, 1998
1HJF
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ALTERATION OF THE CO-SUBSTRATE SELECTIVITY OF DEACETOXYCEPHALOSPORIN C SYNTHASE: THE ROLE OF ARGININE-258
Descriptor:DEACETOXYCEPHALOSPORIN C SYNTHASE, FE (II) ION, 2-OXO-4-METHYLPENTANOIC ACID
Authors:Lee, H.J., Lloyd, M.D., Clifton, I.J., Harlos, K., Dubus, A., Baldwin, J.E., Frere, J.M., Schofield, C.J.
Deposit date:2001-01-15
Release date:2001-06-01
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Alteration of the 2-Oxoacid Cosubstrate Selectivity in Deacetoxycephalosporin C Synthase: The Role of Arginine-258
J.Biol.Chem., 276, 2001
1HJG
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ALTERATION OF THE CO-SUBSTRATE SELECTIVITY OF DEACETOXYCEPHALOSPORIN C SYNTHASE: THE ROLE OF ARGININE-258
Descriptor:DEACETOXYCEPHALOSPORIN C SYNTHASE, FE (II) ION, 3-METHYL-2-OXOBUTANOIC ACID
Authors:Lee, H.J., Lloyd, M.D., Clifton, I.J., Harlos, K., Dubus, A., Baldwin, J.E., Frere, J.M., Schofield, C.J.
Deposit date:2001-01-15
Release date:2001-06-01
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Alteration of the 2-Oxoacid Cosubstrate Selectivity in Deacetoxycephalosporin C Synthase: The Role of Arginine-258
J.Biol.Chem., 276, 2001
1E5H
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DELTA-R307A DEACETOXYCEPHALOSPORIN C SYNTHASE COMPLEXED WITH SUCCINATE AND CARBON DIOXIDE
Descriptor:DEACETOXYCEPHALOSPORIN C SYNTHASE, FE (II) ION, SUCCINIC ACID, ...
Authors:Lee, H.J., Lloyd, M.D., Harlos, K., Clifton, I.J., Baldwin, J.E., Schofield, C.J.
Deposit date:2000-07-26
Release date:2001-07-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Kinetic and Crystallographic Studies on Deacetoxycephalosporin C Synthase (Daocs)
J.Mol.Biol., 308, 2001
1E5I
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DELTA-R306 DEACETOXYCEPHALOSPORIN C SYNTHASE COMPLEXED WITH IRON AND 2-OXOGLUTARATE.
Descriptor:DEACETOXYCEPHALOSPORIN C SYNTHASE, FE (II) ION, 2-OXOGLUTARIC ACID
Authors:Lee, H.J., Lloyd, M.D., Harlos, K., Clifton, I.J., Baldwin, J.E., Schofield, C.J.
Deposit date:2000-07-26
Release date:2001-07-26
Last modified:2011-08-24
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Kinetic and Crystallographic Studies on Deacetoxycephalosporin C Synthase (Daocs)
J.Mol.Biol., 308, 2001
1WT3
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MUTANT HUMAN ABO(H) BLOOD GROUP GLYCOSYLTRANSFERASE WITH BOUND UDP AND ACCEPTOR
Descriptor:Histo-blood group ABO system transferase, 2-HEXYLOXY-6-HYDROXYMETHYL-TETRAHYDRO-PYRAN-3,4,5-TRIOL, ALPHA-L-FUCOSE, ...
Authors:Lee, H.J., Barry, C.H., Borisova, S.N., Seto, N.O.L., Zheng, R.B., Blancher, A., Evans, S.V., Palcic, M.M.
Deposit date:2004-11-12
Release date:2004-12-03
Last modified:2012-06-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for the inactivity of human blood group o2 glycosyltransferase
J.Biol.Chem., 280, 2005
1WSZ
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MUTANT HUMAN ABO(H) BLOOD GROUP TRANSFERASE A
Descriptor:Histo-blood group ABO system transferase, MERCURY (II) ION
Authors:Lee, H.J., Barry, C.H., Borisova, S.N., Seto, N.O.L., Zheng, R.B., Blancher, A., Evans, S.V., Palcic, M.M.
Deposit date:2004-11-12
Release date:2004-12-07
Last modified:2018-08-15
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Structural basis for the inactivity of human blood group o2 glycosyltransferase
J.Biol.Chem., 280, 2005
1WT0
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MUTANT HUMAN ABO(H) BLOOD GROUP GLYCOSYLTRANSFERASE A
Descriptor:Histo-blood group ABO system transferase, MERCURY (II) ION
Authors:Lee, H.J., Barry, C.H., Borisova, S.N., Seto, N.O.L., Zheng, R.B., Blancher, A., Evans, S.V., Palcic, M.M.
Deposit date:2004-11-12
Release date:2004-12-07
Last modified:2018-08-15
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for the inactivity of human blood group o2 glycosyltransferase
J.Biol.Chem., 280, 2005
1WT1
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MUTANT ABO(H) BLOOD GROUP GLYCOSYLTRANSFERASE WITH BOUND UDP AND ACCEPTOR
Descriptor:Histo-blood group ABO system transferase, 2-HEXYLOXY-6-HYDROXYMETHYL-TETRAHYDRO-PYRAN-3,4,5-TRIOL, ALPHA-L-FUCOSE, ...
Authors:Lee, H.J., Barry, C.H., Borisova, S.N., Seto, N.O.L., Zheng, R.B., Blancher, A., Evans, S.V., Palcic, M.M.
Deposit date:2004-11-12
Release date:2004-12-07
Last modified:2012-06-20
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structural basis for the inactivity of human blood group o2 glycosyltransferase
J.Biol.Chem., 280, 2005
1WT2
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MUTANT HUMAN ABO(H) BLOOD GROUP GLYCOSYLTRANSFERASE A WITH BOUND UDP AND INHIBITOR
Descriptor:Histo-blood group ABO system transferase, HEXYL 3-DEOXY-BETA-D-GALACTOPYRANOSE, ALPHA-L-FUCOSE, ...
Authors:Lee, H.J., Barry, C.H., Borisova, S.N., Seto, N.O.L., Zheng, R.B., Blancher, A., Evans, S.V., Palcic, M.M.
Deposit date:2004-11-12
Release date:2004-12-07
Last modified:2012-06-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for the inactivity of human blood group o2 glycosyltransferase
J.Biol.Chem., 280, 2005
1XZ6
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MUTANT ABO(H) BLOOD GROUP GLYCOSYLTRANSFERASE A
Descriptor:Histo-blood group ABO system transferase, MERCURY (II) ION
Authors:Lee, H.J., Barry, C.H., Borisova, S.N., Seto, N.O.L., Zheng, R.B., Blancher, A., Evans, S.V., Palcic, M.M.
Deposit date:2004-11-11
Release date:2004-12-07
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structural basis for the inactivity of human blood group O2 glycosyltransferase
J.Biol.Chem., 280, 2005
1XWO
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CRYSTAL STRUCTRUE OF GOOSE DELTA CRYSTALLIN
Descriptor:Delta crystallin
Authors:Lee, H.J., Lai, Y.H., Wu, S.Y., Chang, G.G.
Deposit date:2004-11-02
Release date:2005-10-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The effect of N-terminal truncation on double-dimer assembly of goose delta-crystallin
Biochem.J., 392, 2005
2G0G
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STRUCTURE-BASED DRUG DESIGN OF A NOVEL FAMILY OF PPAR PARTIAL AGONISTS: VIRTUAL SCREENING, X-RAY CRYSTALLOGRAPHY AND IN VITRO/IN VIVO BIOLOGICAL ACTIVITIES
Descriptor:Peroxisome proliferator-activated receptor gamma, 3-FLUORO-N-[1-(4-FLUOROPHENYL)-3-(2-THIENYL)-1H-PYRAZOL-5-YL]BENZENESULFONAMIDE
Authors:Lu, I.L., Peng, Y.H., Huang, C.F., Lin, Y.T., Hsu, J.T.A., Wu, S.Y.
Deposit date:2006-02-13
Release date:2006-05-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.54 Å)
Cite:Structure-Based Drug Design of a Novel Family of PPARgamma Partial Agonists: Virtual Screening, X-ray Crystallography, and in Vitro/in Vivo Biological Activities
J.Med.Chem., 49, 2006
2G0H
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STRUCTURE-BASED DRUG DESIGN OF A NOVEL FAMILY OF PPAR PARTIAL AGONISTS: VIRTUAL SCREENING, X-RAY CRYSTALLOGRAPHY AND IN VITRO/IN VIVO BIOLOGICAL ACTIVITIES
Descriptor:Peroxisome proliferator-activated receptor gamma, N-[1-(4-FLUOROPHENYL)-3-(2-THIENYL)-1H-PYRAZOL-5-YL]-3,5-BIS(TRIFLUOROMETHYL)BENZENESULFONAMIDE
Authors:Lu, I.L., Peng, Y.H., Huang, C.F., Lin, Y.T., Hsu, J.T.A., Wu, S.Y.
Deposit date:2006-02-13
Release date:2006-05-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure-Based Drug Design of a Novel Family of PPARgamma Partial Agonists: Virtual Screening, X-ray Crystallography, and in Vitro/in Vivo Biological Activities
J.Med.Chem., 49, 2006
2HWQ
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STRUCTURAL BASIS FOR THE STRUCTURE-ACTIVITY RELATIONSHIPS OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR AGONISTS
Descriptor:Peroxisome proliferator-activated receptor gamma, [(1-{3-[(6-BENZOYL-1-PROPYL-2-NAPHTHYL)OXY]PROPYL}-1H-INDOL-5-YL)OXY]ACETIC ACID
Authors:Peng, Y.H., Lu, I.L., Mahindroo, N., Lin, C.H., Hsieh, H.P., Wu, S.Y.
Deposit date:2006-08-01
Release date:2007-08-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Structural basis for the structure-activity relationships of peroxisome proliferator-activated receptor agonists
J.Med.Chem., 49, 2006
2HWR
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STRUCTURAL BASIS FOR THE STRUCTURE-ACTIVITY RELATIONSHIPS OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR AGONISTS
Descriptor:Peroxisome proliferator-activated receptor gamma, 2-[(1-{3-[(6-BENZOYL-1-PROPYL-2-NAPHTHYL)OXY]PROPYL}-1H-INDOL-4-YL)OXY]-2-METHYLPROPANOIC ACID
Authors:Peng, Y.H., Lu, I.L., Mahindroo, N., Lin, C.H., Hsieh, H.P., Wu, S.Y.
Deposit date:2006-08-01
Release date:2007-08-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Structural basis for the structure-activity relationships of peroxisome proliferator-activated receptor agonists
J.Med.Chem., 49, 2006
2R0M
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THE EFFECT OF A GLU370ASP MUTATION IN GLUTARYL-COA DEHYDROGENASE ON PROTON TRANSFER TO THE DIENOLATE INTERMEDIATE
Descriptor:Glutaryl-CoA dehydrogenase, FLAVIN-ADENINE DINUCLEOTIDE, 4-nitrobutanoic acid
Authors:Rao, K.S., Fu, Z., Albro, M., Narayanan, B., Baddam, S., Lee, H.J., Kim, J.J., Frerman, F.E.
Deposit date:2007-08-20
Release date:2008-04-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The effect of a Glu370Asp mutation in glutaryl-CoA dehydrogenase on proton transfer to the dienolate intermediate.
Biochemistry, 46, 2007
2R0N
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THE EFFECT OF A GLU370ASP MUTATION IN GLUTARYL-COA DEHYDROGENASE ON PROTON TRANSFER TO THE DIENOLATE INTERMEDIATE
Descriptor:Glutaryl-CoA dehydrogenase, FLAVIN-ADENINE DINUCLEOTIDE, 3-thiaglutaryl-CoA
Authors:Rao, K.S., Albro, M., Fu, Z., Narayanan, B., Baddam, S., Lee, H.J., Kim, J.J., Frerman, F.E.
Deposit date:2007-08-20
Release date:2008-04-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The effect of a Glu370Asp mutation in glutaryl-CoA dehydrogenase on proton transfer to the dienolate intermediate.
Biochemistry, 46, 2007
2WLC
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CRYSTALLOGRAPHIC ANALYSIS OF THE POLYSIALIC ACID O-ACETYLTRANSFERASE OATWY
Descriptor:POLYSIALIC ACID O-ACETYLTRANSFERASE, ACETATE ION, 1,2-ETHANEDIOL, ...
Authors:Lee, H.J., Rakic, B., Gilbert, M., Wakarchuk, W.W., Withers, S.G., Strynadka, N.C.J.
Deposit date:2009-06-23
Release date:2009-06-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural and Kinetic Characterizations of the Polysialic Acid O-Acetyltransferase Oatwy from Neisseria Meningitidis.
J.Biol.Chem., 284, 2009
2WLE
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CRYSTALLOGRAPHIC ANALYSIS OF THE POLYSIALIC ACID O-ACETYLTRANSFERASE OATWY
Descriptor:POLYSIALIC ACID O-ACETYLTRANSFERASE, COENZYME A, 1,2-ETHANEDIOL, ...
Authors:Lee, H.J., Rakic, B., Gilbert, M., Wakarchuk, W.W., Withers, S.G., Strynadka, N.C.J.
Deposit date:2009-06-23
Release date:2009-06-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Structural and Kinetic Characterizations of the Polysialic Acid O-Acetyltransferase Oatwy from Neisseria Meningitidis.
J.Biol.Chem., 284, 2009
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