Author results

6IM5
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YAP-BINDING DOMAIN OF HUMAN TEAD1
Descriptor:Transcriptional enhancer factor TEF-1, PHOSPHATE ION
Authors:Mo, Y., Lee, H.S., Kim, S.J., Ku, B.
Deposit date:2018-10-22
Release date:2019-02-06
Method:X-RAY DIFFRACTION (1.701 Å)
Cite:Crystal Structure of the YAP-binding Domain of Human TEAD1
Bull.Korean Chem.Soc., 40, 2019
6CNO
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CRYO-EM STRUCTURE OF THE HUMAN SK4/CALMODULIN CHANNEL COMPLEX IN THE CA2+ BOUND STATE II
Descriptor:Intermediate conductance calcium-activated potassium channel protein 4, Calmodulin-1, CALCIUM ION
Authors:Lee, C.H., MacKinnon, R.
Deposit date:2018-03-08
Release date:2018-05-02
Last modified:2018-05-23
Method:ELECTRON MICROSCOPY (4.7 Å)
Cite:Activation mechanism of a human SK-calmodulin channel complex elucidated by cryo-EM structures.
Science, 360, 2018
6CNN
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CRYO-EM STRUCTURE OF THE HUMAN SK4/CALMODULIN CHANNEL COMPLEX IN THE CA2+ BOUND STATE I
Descriptor:Intermediate conductance calcium-activated potassium channel protein 4, Calmodulin-1, POTASSIUM ION, ...
Authors:Lee, C.H., MacKinnon, R.
Deposit date:2018-03-08
Release date:2018-05-02
Last modified:2018-05-23
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Activation mechanism of a human SK-calmodulin channel complex elucidated by cryo-EM structures.
Science, 360, 2018
6CNM
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CRYO-EM STRUCTURE OF THE HUMAN SK4/CALMODULIN CHANNEL COMPLEX
Descriptor:Intermediate conductance calcium-activated potassium channel protein 4, Calmodulin-1, POTASSIUM ION, ...
Authors:Lee, C.H., MacKinnon, R.
Deposit date:2018-03-08
Release date:2018-05-02
Last modified:2018-05-23
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Activation mechanism of a human SK-calmodulin channel complex elucidated by cryo-EM structures.
Science, 360, 2018
5Y41
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CRYSTAL STRUCTURE OF LIGAND-BOUND NURR1-LBD
Descriptor:Nuclear receptor subfamily 4 group A member 2, (13E,15S)-15-hydroxy-9-oxoprosta-10,13-dien-1-oic acid, TRIETHYLENE GLYCOL, ...
Authors:Sreekanth, R., Lescar, J., Yoon, H.S.
Deposit date:2017-07-31
Release date:2018-12-26
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Co-crystal structure and function of Nurr1 bound to the cyclopentenone prostaglandin A1
To be published
5V4E
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ENGINEERED HUMAN IGG FC DOMAIN GLYCO801 (FC801)
Descriptor:Ig gamma-1 chain C region, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Yan, W., Marshall, N., Zhang, Y.J.
Deposit date:2017-03-09
Release date:2017-06-21
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (3.216 Å)
Cite:IgG Fc domains that bind C1q but not effector Fc gamma receptors delineate the importance of complement-mediated effector functions.
Nat. Immunol., 18, 2017
5V43
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ENGINEERED HUMAN IGG FC DOMAIN AGLYCO801
Descriptor:Ig gamma-1 chain C region
Authors:Yan, W., Marshall, N., Zhang, Y.J.
Deposit date:2017-03-08
Release date:2017-06-21
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:IgG Fc domains that bind C1q but not effector Fc gamma receptors delineate the importance of complement-mediated effector functions.
Nat. Immunol., 18, 2017
5UN1
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CRYSTAL STRUCTURE OF GLUN1/GLUN2B DELTA-ATD NMDA RECEPTOR
Descriptor:N-methyl-D-aspartate receptor subunit NR1-3a, Ionotropic glutamate receptor subunit NR2B, GLYCINE, ...
Authors:Song, X., Gouaux, E.
Deposit date:2017-01-30
Release date:2018-02-07
Last modified:2018-05-02
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Mechanism of NMDA receptor channel block by MK-801 and memantine.
Nature, 556, 2018
5U6P
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STRUCTURE OF THE HUMAN HCN1 HYPERPOLARIZATION-ACTIVATED CYCLIC NUCLEOTIDE-GATED ION CHANNEL IN COMPLEX WITH CAMP
Descriptor:Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 11, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE
Authors:Lee, C.-H., MacKinnon, R.
Deposit date:2016-12-08
Release date:2017-01-25
Last modified:2017-09-27
Method:ELECTRON MICROSCOPY (3.51 Å)
Cite:Structures of the Human HCN1 Hyperpolarization-Activated Channel.
Cell, 168, 2017
5U6O
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STRUCTURE OF THE HUMAN HCN1 HYPERPOLARIZATION-ACTIVATED CYCLIC NUCLEOTIDE-GATED ION CHANNEL
Descriptor:Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1
Authors:Lee, C.-H., MacKinnon, R.
Deposit date:2016-12-08
Release date:2017-01-25
Last modified:2017-09-27
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structures of the Human HCN1 Hyperpolarization-Activated Channel.
Cell, 168, 2017
5IPV
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CRYO-EM STRUCTURE OF GLUN1/GLUN2B NMDA RECEPTOR IN THE DCKA/D-APV-BOUND CONFORMATION, STATE 1
Descriptor:N-methyl-D-aspartate receptor subunit NR1-8a, Ionotropic glutamate receptor subunit NR2B
Authors:Zhu, S., Stein, A.R., Yoshioka, C., Lee, C.H., Goehring, A., McHaourab, S.H., Gouaux, E.
Deposit date:2016-03-10
Release date:2016-04-20
Method:ELECTRON MICROSCOPY (9.25 Å)
Cite:Mechanism of NMDA Receptor Inhibition and Activation.
Cell, 165, 2016
5IPU
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CRYO-EM STRUCTURE OF GLUN1/GLUN2B NMDA RECEPTOR IN THE DCKA/D-APV-BOUND CONFORMATION, STATE 6
Descriptor:N-methyl-D-aspartate receptor subunit NR1-8a, Ionotropic glutamate receptor subunit NR2B
Authors:Zhu, S., Stein, A.R., Yoshioka, C., Lee, C.H., Goehring, A., Mchaourab, S.H., Gouaux, E.
Deposit date:2016-03-09
Release date:2016-04-20
Last modified:2016-05-04
Method:ELECTRON MICROSCOPY (15.4 Å)
Cite:Mechanism of NMDA Receptor Inhibition and Activation.
Cell, 165, 2016
5IPT
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CRYO-EM STRUCTURE OF GLUN1/GLUN2B NMDA RECEPTOR IN THE DCKA/D-APV-BOUND CONFORMATION, STATE 5
Descriptor:N-methyl-D-aspartate receptor subunit NR1-8a, Ionotropic glutamate receptor subunit NR2B
Authors:Zhu, S., Stein, A.R., Yoshioka, C., Lee, C.H., Goehring, A., Mchaourab, S.H., Gouaux, E.
Deposit date:2016-03-09
Release date:2016-04-20
Last modified:2016-05-04
Method:ELECTRON MICROSCOPY (14.1 Å)
Cite:Mechanism of NMDA Receptor Inhibition and Activation.
Cell, 165, 2016
5IPS
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CRYO-EM STRUCTURE OF GLUN1/GLUN2B NMDA RECEPTOR IN THE DCKA/D-APV-BOUND CONFORMATION, STATE 4
Descriptor:N-methyl-D-aspartate receptor subunit NR1-8a, Ionotropic glutamate receptor subunit NR2B
Authors:Zhu, S., Stein, A.R., Yoshioka, C., Lee, C.H., Goehring, A., Mchaourab, S.H., Gouaux, E.
Deposit date:2016-03-09
Release date:2016-04-20
Last modified:2016-05-04
Method:ELECTRON MICROSCOPY (13.5 Å)
Cite:Mechanism of NMDA Receptor Inhibition and Activation.
Cell, 165, 2016
5IPR
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CRYO-EM STRUCTURE OF GLUN1/GLUN2B NMDA RECEPTOR IN THE DCKA/D-APV-BOUND CONFORMATION, STATE 3
Descriptor:N-methyl-D-aspartate receptor subunit NR1-8a, Ionotropic glutamate receptor subunit NR2B
Authors:Zhu, S., Stein, A.R., Yoshioka, C., Lee, C.H., Goehring, A., Mchaourab, S.H., Gouaux, E.
Deposit date:2016-03-09
Release date:2016-04-20
Last modified:2016-05-04
Method:ELECTRON MICROSCOPY (14.1 Å)
Cite:Mechanism of NMDA Receptor Inhibition and Activation.
Cell, 165, 2016
5IPQ
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CRYO-EM STRUCTURE OF GLUN1/GLUN2B NMDA RECEPTOR IN THE DCKA/D-APV-BOUND CONFORMATION, STATE 2
Descriptor:N-methyl-D-aspartate receptor subunit NR1-8a, Ionotropic glutamate receptor subunit NR2B
Authors:Zhu, S., Stein, A.R., Yoshioka, C., Lee, C.H., Goehring, A., Mchaourab, S.H., Gouaux, E.
Deposit date:2016-03-09
Release date:2016-04-20
Last modified:2016-05-04
Method:ELECTRON MICROSCOPY (13.5 Å)
Cite:Mechanism of NMDA Receptor Inhibition and Activation.
Cell, 165, 2016
5IOV
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CRYO-EM STRUCTURE OF GLUN1/GLUN2B NMDA RECEPTOR IN THE GLUTAMATE/GLYCINE/RO25-6981-BOUND CONFORMATION
Descriptor:N-methyl-D-aspartate receptor subunit NR1-8a, Ionotropic glutamate receptor subunit NR2B, GLYCINE, ...
Authors:Zhu, S., Stein, A.R., Yoshioka, C., Lee, C.H., Goehring, A., Mchaourab, S.H., Gouaux, E.
Deposit date:2016-03-09
Release date:2016-04-20
Last modified:2016-05-04
Method:ELECTRON MICROSCOPY (7.5 Å)
Cite:Mechanism of NMDA Receptor Inhibition and Activation.
Cell, 165, 2016
5IOU
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CRYO-EM STRUCTURE OF GLUN1/GLUN2B NMDA RECEPTOR IN THE GLUTAMATE/GLYCINE-BOUND CONFORMATION
Descriptor:N-methyl-D-aspartate receptor subunit NR1-8a, Ionotropic glutamate receptor subunit NR2B, GLYCINE, ...
Authors:Zhu, S., Stein, A.R., Yoshioka, C., Lee, C.H., Goehring, A., Mchaourab, S.H., Gouaux, E.
Deposit date:2016-03-09
Release date:2016-04-20
Last modified:2016-05-04
Method:ELECTRON MICROSCOPY (7 Å)
Cite:Mechanism of NMDA Receptor Inhibition and Activation.
Cell, 165, 2016
5ICT
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CRYSTAL STRUCTURE OF THE DROSOPHILA GLUR1A LIGAND BINDING DOMAIN Y792T MUTANT COMPLEX WITH GLUTAMATE
Descriptor:Glutamate receptor 1, GLUTAMIC ACID, GLYCEROL
Authors:Dharkar, P., Mayer, M.L.
Deposit date:2016-02-23
Release date:2016-12-21
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Novel Functional Properties of Drosophila CNS Glutamate Receptors.
Neuron, 92, 2016
5EHS
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CRYSTAL STRUCTURE OF THE DROSOPHILA CG3822 KAIR1D LIGAND BINDING DOMAIN COMPLEX WITH D-AP5
Descriptor:RE06730p,GH17276, 5-phosphono-D-norvaline, 5-phosphono-L-norvaline
Authors:Dharkar, P., Mayer, M.L.
Deposit date:2015-10-28
Release date:2016-11-09
Last modified:2016-12-21
Method:X-RAY DIFFRACTION (1.749 Å)
Cite:Novel Functional Properties of Drosophila CNS Glutamate Receptors.
Neuron, 92, 2016
5EHM
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CRYSTAL STRUCTURE OF THE DROSOPHILA CG3822 KAIR1D LIGAND BINDING DOMAIN COMPLEX WITH NMDA
Descriptor:RE06730p,CG3822, N-methyl-D-aspartic acid
Authors:Dharkar, P., Mayer, M.L.
Deposit date:2015-10-28
Release date:2016-11-09
Last modified:2016-12-21
Method:X-RAY DIFFRACTION (1.281 Å)
Cite:Novel Functional Properties of Drosophila CNS Glutamate Receptors.
Neuron, 92, 2016
5DTB
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CRYSTAL STRUCTURE OF THE DROSOPHILA CG3822 KAIR1D LIGAND BINDING DOMAIN COMPLEX WITH GLUTAMATE
Descriptor:CG3822, GLUTAMIC ACID, GLYCEROL, ...
Authors:Dharkar, P., Mayer, M.L.
Deposit date:2015-09-17
Release date:2016-09-28
Last modified:2016-12-21
Method:X-RAY DIFFRACTION (1.843 Å)
Cite:Novel Functional Properties of Drosophila CNS Glutamate Receptors.
Neuron, 92, 2016
5DT6
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CRYSTAL STRUCTURE OF THE DROSOPHILA GLUR1A LIGAND BINDING DOMAIN COMPLEX WITH GLUTAMATE
Descriptor:Glutamate receptor 1, GLUTAMIC ACID, GLYCEROL
Authors:Dharkar, P., Mayer, M.L.
Deposit date:2015-09-17
Release date:2016-09-28
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.598 Å)
Cite:Novel Functional Properties of Drosophila CNS Glutamate Receptors.
Neuron, 92, 2016
4TLM
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CRYSTAL STRUCTURE OF GLUN1/GLUN2B NMDA RECEPTOR, STRUCTURE 2
Descriptor:receptor subunit GluN1, receptor subunit GluN2B, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Gouaux, E., Lee, C.-H., Lu, W.
Deposit date:2014-05-30
Release date:2014-07-02
Last modified:2014-09-24
Method:X-RAY DIFFRACTION (3.77 Å)
Cite:NMDA receptor structures reveal subunit arrangement and pore architecture.
Nature, 511, 2014
4TLL
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CRYSTAL STRUCTURE OF GLUN1/GLUN2B NMDA RECEPTOR, STRUCTURE 1
Descriptor:receptor subunit GluN1, receptor subunit GluN2B, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Gouaux, E., Lee, C.-H., Lu, W.
Deposit date:2014-05-30
Release date:2014-07-02
Last modified:2014-09-24
Method:X-RAY DIFFRACTION (3.59 Å)
Cite:NMDA receptor structures reveal subunit arrangement and pore architecture.
Nature, 511, 2014
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