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4Z1H
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BU of 4z1h by Molmil
Crystal structure of human Trap1 with SMTIN-P01
Descriptor: 8-[(6-iodo-1,3-benzodioxol-5-yl)sulfanyl]-9-[6-(triphenyl-lambda~5~-phosphanyl)hexyl]-9H-purin-6-amine, Heat shock protein 75 kDa, mitochondrial
Authors:Lee, C, Park, H.K, Ryu, J.H, Kang, B.H.
Deposit date:2015-03-27
Release date:2015-04-22
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Development of a Mitochondria-Targeted Hsp90 Inhibitor Based on the Crystal Structures of Human TRAP1
J.Am.Chem.Soc., 137, 2015
4Z1I
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BU of 4z1i by Molmil
Crystal structure of human Trap1 with AMPPNP
Descriptor: Heat shock protein 75 kDa, mitochondrial, MAGNESIUM ION, ...
Authors:Lee, C, Park, H.K, Ryu, J.H, Kang, B.H.
Deposit date:2015-03-27
Release date:2015-04-29
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Development of a Mitochondria-Targeted Hsp90 Inhibitor Based on the Crystal Structures of Human TRAP1
J.Am.Chem.Soc., 137, 2015
4Z1G
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BU of 4z1g by Molmil
Crystal structure of human Trap1 with BIIB-021
Descriptor: 6-chloro-9-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]-9H-purin-2-amine, Heat shock protein 75 kDa, mitochondrial
Authors:Lee, C, Park, H.K, Ryu, J.H, Kang, B.H.
Deposit date:2015-03-27
Release date:2015-04-22
Last modified:2022-10-05
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Development of a Mitochondria-Targeted Hsp90 Inhibitor Based on the Crystal Structures of Human TRAP1
J.Am.Chem.Soc., 137, 2015
4Z1F
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BU of 4z1f by Molmil
Crystal structure of human Trap1 with PU-H71
Descriptor: 8-[(6-IODO-1,3-BENZODIOXOL-5-YL)THIO]-9-[3-(ISOPROPYLAMINO)PROPYL]-9H-PURIN-6-AMINE, Heat shock protein 75 kDa, mitochondrial
Authors:Lee, C, Park, H.K, Ryu, J.H, Kang, B.H.
Deposit date:2015-03-27
Release date:2015-04-22
Method:X-RAY DIFFRACTION (2.703 Å)
Cite:Development of a Mitochondria-Targeted Hsp90 Inhibitor Based on the Crystal Structures of Human TRAP1
J.Am.Chem.Soc., 137, 2015
1IZ3
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BU of 1iz3 by Molmil
Dimeric structure of FIH (Factor inhibiting HIF)
Descriptor: FIH, SULFATE ION
Authors:Lee, C, Kim, S.-J, Jeong, D.-G, Lee, S.M, Ryu, S.-E.
Deposit date:2002-09-19
Release date:2003-06-10
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of human FIH-1 reveals a unique active site pocket and interaction sites for HIF-1 and von Hippel-Lindau.
J.Biol.Chem., 278, 2003
1N4M
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BU of 1n4m by Molmil
Structure of Rb tumor suppressor bound to the transactivation domain of E2F-2
Descriptor: Retinoblastoma Pocket, Transcription factor E2F2
Authors:Lee, C, Chang, J.H, Lee, H.S, Cho, Y.
Deposit date:2002-10-31
Release date:2003-01-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis for the recognition of the E2F transactivation domain by the retinoblastoma tumor suppressor
GENES DEV., 16, 2002
5VRE
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BU of 5vre by Molmil
Crystal structure of a lysosomal potassium-selective channel TMEM175 homolog from Chamaesiphon Minutus
Descriptor: Putative integral membrane protein
Authors:Lee, C, Guo, J, Jiang, Y.
Deposit date:2017-05-10
Release date:2017-07-19
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3.299 Å)
Cite:The lysosomal potassium channel TMEM175 adopts a novel tetrameric architecture.
Nature, 547, 2017
4BWZ
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BU of 4bwz by Molmil
Crystal structure of the sodium proton antiporter, NapA
Descriptor: NA(+)/H(+) ANTIPORTER, ZINC ION
Authors:Lee, C, Drew, D, Cameron, A.D.
Deposit date:2013-07-05
Release date:2013-08-28
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (2.984 Å)
Cite:A two-domain elevator mechanism for sodium/proton antiport.
Nature, 501, 2013
5H20
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BU of 5h20 by Molmil
X-ray structure of PadR-like Transcription factor from bacteroid fragilis
Descriptor: ISOPROPYL ALCOHOL, PHOSPHATE ION, Putative PadR-family transcriptional regulatory protein, ...
Authors:Lee, C, Hong, M.
Deposit date:2016-10-13
Release date:2017-03-08
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural and functional analysis of BF2549, a PadR-like transcription factor from Bacteroides fragilis.
Biochem. Biophys. Res. Commun., 483, 2017
5XEF
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BU of 5xef by Molmil
Crystal structure of flagellar chaperone from bacteria
Descriptor: Flagellar protein fliS
Authors:Lee, C, Hong, M.
Deposit date:2017-04-05
Release date:2018-06-27
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of the flagellar chaperone FliS from Bacillus cereus and an invariant proline critical for FliS dimerization and flagellin recognition
Biochem. Biophys. Res. Commun., 487, 2017
6ABT
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BU of 6abt by Molmil
Crystal structure of transcription factor from Listeria monocytogenes
Descriptor: PadR family transcriptional regulator
Authors:Lee, C, Hong, M.
Deposit date:2018-07-23
Release date:2019-06-05
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure-based molecular characterization and regulatory mechanism of the LftR transcription factor from Listeria monocytogenes: Conformational flexibilities and a ligand-induced regulatory mechanism.
Plos One, 14, 2019
6ABQ
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BU of 6abq by Molmil
Crystal structure of transcription factor from Listeria monocytogenes
Descriptor: CHLORIDE ION, PadR family transcriptional regulator
Authors:Lee, C, Hong, M.
Deposit date:2018-07-23
Release date:2019-06-05
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure-based molecular characterization and regulatory mechanism of the LftR transcription factor from Listeria monocytogenes: Conformational flexibilities and a ligand-induced regulatory mechanism.
Plos One, 14, 2019
3MKR
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BU of 3mkr by Molmil
Crystal structure of yeast alpha/epsilon-COP subcomplex of the COPI vesicular coat
Descriptor: Coatomer subunit alpha, Coatomer subunit epsilon
Authors:Lee, C, Goldberg, J.
Deposit date:2010-04-15
Release date:2010-07-14
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of coatomer cage proteins and the relationship among COPI, COPII, and clathrin vesicle coats.
Cell(Cambridge,Mass.), 142, 2010
3MKQ
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BU of 3mkq by Molmil
Crystal structure of yeast alpha/betaprime-COP subcomplex of the COPI vesicular coat
Descriptor: Coatomer beta'-subunit, Coatomer subunit alpha
Authors:Lee, C, Goldberg, J.
Deposit date:2010-04-15
Release date:2010-07-14
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of coatomer cage proteins and the relationship among COPI, COPII, and clathrin vesicle coats.
Cell(Cambridge,Mass.), 142, 2010
2JRL
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BU of 2jrl by Molmil
Solution structure of the beryllofluoride-activated NtrC4 receiver domain dimer
Descriptor: Transcriptional regulator (NtrC family)
Authors:Lee, C, Hong, E, Doucleff, M, Pelton, J.G, Wemmer, D.E, Berkeley Structural Genomics Center (BSGC)
Deposit date:2007-06-27
Release date:2008-07-01
Last modified:2020-02-19
Method:SOLUTION NMR
Cite:Solution Structure of the Beryllofluoride-Activated NtrC4 Receiver Domain Dimer.
To be Published
4ATV
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BU of 4atv by Molmil
STRUCTURE OF A TRIPLE MUTANT OF THE NHAA DIMER, CRYSTALLISED AT LOW PH
Descriptor: DODECYL-ALPHA-D-MALTOSIDE, NA(+)/H(+) ANTIPORTER NHAA, SULFATE ION
Authors:Drew, D, Lee, C, Iwata, S, Cameron, A.D.
Deposit date:2012-05-10
Release date:2013-07-10
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Crystal structure of the sodium-proton antiporter NhaA dimer and new mechanistic insights.
J. Gen. Physiol., 144, 2014
4AU5
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BU of 4au5 by Molmil
Structure of the NhaA dimer, crystallised at low pH
Descriptor: DODECYL-ALPHA-D-MALTOSIDE, NA(+)/H(+) ANTIPORTER NHAA, SULFATE ION
Authors:Drew, D, Lee, C, Iwata, S, Cameron, A.D.
Deposit date:2012-05-14
Release date:2013-07-10
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.696 Å)
Cite:Crystal structure of the sodium-proton antiporter NhaA dimer and new mechanistic insights.
J. Gen. Physiol., 144, 2014
2ZXX
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BU of 2zxx by Molmil
Crystal structure of Cdt1/geminin complex
Descriptor: DNA replication factor Cdt1, Geminin
Authors:Cho, Y, Lee, C, Hong, B.S, Choi, J.M.
Deposit date:2009-01-08
Release date:2009-02-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for inhibition of the replication licensing factor Cdt1 by geminin
Nature, 430, 2004
2JTN
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BU of 2jtn by Molmil
NMR Solution Structure of a ldb1-LID:Lhx3-LIM complex
Descriptor: LIM domain-binding protein 1, LIM/homeobox protein Lhx3, ZINC ION
Authors:Lee, C, Nancarrow, A.L, Mackay, J.P, Matthews, J.M.
Deposit date:2007-08-03
Release date:2008-06-17
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Implementing the LIM code: the structural basis for cell type-specific assembly of LIM-homeodomain complexes
Embo J., 27, 2008
2HIW
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BU of 2hiw by Molmil
Crystal Structure of Inactive Conformation Abl Kinase Catalytic Domain Complexed with Type II Inhibitor
Descriptor: 7-AMINO-1-METHYL-3-(2-METHYL-5-{[3-(TRIFLUOROMETHYL)BENZOYL]AMINO}PHENYL)-2-OXO-2,3-DIHYDROPYRIMIDO[4,5-D]PYRIMIDIN-1-IUM, Proto-oncogene tyrosine-protein kinase ABL1
Authors:Lee, C.
Deposit date:2006-06-29
Release date:2006-08-22
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A general strategy for creating
Chem.Biol., 13, 2006
7C04
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BU of 7c04 by Molmil
Crystal structure of human Trap1 with DN203492
Descriptor: 4-chloranyl-1-[[2-methoxy-4-(trifluoromethyl)phenyl]methyl]pyrazolo[3,4-d]pyrimidin-6-amine, Heat shock protein 75 kDa, mitochondrial
Authors:Kim, D, Kim, D, Kim, S.Y, Lee, J.H, Kang, B.H, Kang, S, Lee, C.
Deposit date:2020-04-30
Release date:2020-07-08
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Development of pyrazolo[3,4-d]pyrimidine-6-amine-based TRAP1 inhibitors that demonstrate in vivo anticancer activity in mouse xenograft models.
Bioorg.Chem., 101, 2020
7C05
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BU of 7c05 by Molmil
Crystal structure of human Trap1 with DN203495
Descriptor: 1-[(4-bromanyl-2-fluoranyl-phenyl)methyl]-4-chloranyl-pyrazolo[3,4-d]pyrimidin-6-amine, Heat shock protein 75 kDa, mitochondrial
Authors:Kim, D, Kim, D, Kim, S.Y, Lee, J.H, Kang, B.H, Kang, S, Lee, C.
Deposit date:2020-04-30
Release date:2020-07-08
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Development of pyrazolo[3,4-d]pyrimidine-6-amine-based TRAP1 inhibitors that demonstrate in vivo anticancer activity in mouse xenograft models.
Bioorg.Chem., 101, 2020
6II2
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BU of 6ii2 by Molmil
Crystal structure of alpha-beta hydrolase (ABH) and Makes Caterpillars Floppy (MCF)-Like effectors of Vibrio vulnificus MO6-24/O
Descriptor: Putative RTX-toxin
Authors:Lee, Y, Kim, B.S, Choi, S, Lee, E.Y, Park, S, Hwang, J, Kwon, Y, Hyung, J, Lee, C, Eom, S.H, Kim, M.H.
Deposit date:2018-10-03
Release date:2019-08-07
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Makes caterpillars floppy-like effector-containing MARTX toxins require host ADP-ribosylation factor (ARF) proteins for systemic pathogenicity.
Proc.Natl.Acad.Sci.USA, 116, 2019
6II0
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BU of 6ii0 by Molmil
Crystal structure of the Makes Caterpillars Floppy (MCF)-Like effector of Vibrio vulnificus MO6-24/O
Descriptor: GLYCEROL, Putative RTX-toxin
Authors:Lee, Y, Kim, B.S, Choi, S, Lee, E.Y, Park, S, Hwang, J, Kwon, Y, Hyun, J, Lee, C, Eom, S.H, Kim, M.H.
Deposit date:2018-10-03
Release date:2019-08-07
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:Makes caterpillars floppy-like effector-containing MARTX toxins require host ADP-ribosylation factor (ARF) proteins for systemic pathogenicity.
Proc.Natl.Acad.Sci.USA, 116, 2019
6II6
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BU of 6ii6 by Molmil
Crystal structure of the Makes Caterpillars Floppy (MCF)-Like effector of Vibrio vulnificus MO6-24/O in complex with a human ADP-ribosylation factor 3 (ARF3)
Descriptor: ADP-ribosylation factor 3, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Lee, Y, Kim, B.S, Choi, S, Lee, E.Y, Park, S, Hwang, J, Kwon, Y, Hyun, J, Lee, C, Eom, S.H, Kim, M.H.
Deposit date:2018-10-03
Release date:2019-08-07
Last modified:2020-02-19
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Makes caterpillars floppy-like effector-containing MARTX toxins require host ADP-ribosylation factor (ARF) proteins for systemic pathogenicity.
Proc.Natl.Acad.Sci.USA, 116, 2019

217705

PDB entries from 2024-03-27

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