Author results

1HYE
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CRYSTAL STRUCTURE OF THE MJ0490 GENE PRODUCT, THE FAMILY OF LACTATE/MALATE DEHYDROGENASE, DIMERIC STRUCTURE
Descriptor:L-LACTATE/MALATE DEHYDROGENASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Lee, B.I., Chang, C., Cho, S.-J., Suh, S.W.
Deposit date:2001-01-19
Release date:2001-04-18
Last modified:2018-11-21
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of the MJ0490 gene product of the hyperthermophilic archaebacterium Methanococcus jannaschii, a novel member of the lactate/malate family of dehydrogenases.
J.Mol.Biol., 307, 2001
1HYG
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CRYSTAL STRUCTURE OF MJ0490 GENE PRODUCT, THE FAMILY OF LACTATE/MALATE DEHYDROGENASE
Descriptor:L-LACTATE/MALATE DEHYDROGENASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Lee, B.I., Chang, C., Cho, S.-J., Suh, S.W.
Deposit date:2001-01-19
Release date:2001-04-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of the MJ0490 gene product of the hyperthermophilic archaebacterium Methanococcus jannaschii, a novel member of the lactate/malate family of dehydrogenases
J.Mol.Biol., 307, 2001
1J2Y
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CRYSTAL STRUCTURE OF THE TYPE II 3-DEHYDROQUINASE
Descriptor:3-dehydroquinate dehydratase, 1,3,4-TRIHYDROXY-5-OXO-CYCLOHEXANECARBOXYLIC ACID
Authors:Lee, B.I., Kwak, J.E., Suh, S.W.
Deposit date:2003-01-15
Release date:2003-06-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of the type II 3-dehydroquinase from Helicobacter pylori
Proteins, 51, 2003
1J2Z
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CRYSTAL STRUCTURE OF UDP-N-ACETYLGLUCOSAMINE ACYLTRANSFERASE
Descriptor:Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, 2-HYDROXYMETHYL-6-OCTYLSULFANYL-TETRAHYDRO-PYRAN-3,4,5-TRIOL, SULFATE ION, ...
Authors:Lee, B.I., Suh, S.W.
Deposit date:2003-01-15
Release date:2004-01-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of UDP-N-acetylglucosamine acyltransferase from Helicobacter pylori
Proteins, 53, 2003
1UHD
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CRYSTAL STRUCTURE OF ASPARTATE DECARBOXYLASE, PYRUVOLY GROUP BOUND FORM
Descriptor:Aspartate 1-decarboxylase beta chain, Aspartate 1-decarboxylase alpha chain
Authors:Lee, B.I., Kwon, A.-R., Han, B.W., Suh, S.W.
Deposit date:2003-07-01
Release date:2004-07-13
Last modified:2012-03-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of the schiff base intermediate prior to decarboxylation in the catalytic cycle of aspartate alpha-decarboxylase
J.Mol.Biol., 340, 2004
1UHE
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CRYSTAL STRUCTURE OF ASPARTATE DECARBOXYLASE, ISOASPARGINE COMPLEX
Descriptor:Aspartate 1-decarboxylase beta chain, Aspartate 1-decarboxylase alpha chain, N~2~-(2-AMINO-1-METHYL-2-OXOETHYLIDENE)ASPARAGINATE
Authors:Lee, B.I., Kwon, A.-R., Han, B.W., Suh, S.W.
Deposit date:2003-07-01
Release date:2004-07-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Crystal structure of the schiff base intermediate prior to decarboxylation in the catalytic cycle of aspartate alpha-decarboxylase
J.Mol.Biol., 340, 2004
1VDD
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CRYSTAL STRUCTURE OF RECOMBINATIONAL REPAIR PROTEIN RECR
Descriptor:Recombination protein recR, ZINC ION, IMIDAZOLE
Authors:Lee, B.I., Kim, K.H., Suh, S.W.
Deposit date:2004-03-20
Release date:2004-05-18
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Ring-shaped architecture of RecR: implications for its role in homologous recombinational DNA repair
Embo J., 23, 2004
5GNH
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MYOTUBULARIN-RELATED PROTEIN 2
Descriptor:Myotubularin-related protein 2, PHOSPHATE ION
Authors:Lee, B.I., Bong, S.M.
Deposit date:2016-07-21
Release date:2017-07-26
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of MTMR2
To Be Published
3V6A
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HELICAL REPEAT STRUCTURE OF APOPTOSIS INHIBITOR 5 REVEALS PROTEIN-PROTEIN INTERACTION MODULES
Descriptor:Apoptosis inhibitor 5
Authors:Lee, B.I., Han, B.G., Lee, S.J.
Deposit date:2011-12-19
Release date:2012-02-22
Last modified:2013-07-10
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Helical repeat structure of apoptosis inhibitor 5 reveals protein-protein interaction modules.
J.Biol.Chem., 287, 2012
4RSS
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CRYSTAL STRUCTURE OF TYROSINE-PROTEIN KINASE SYK WITH AN INHIBITOR
Descriptor:Tyrosine-protein kinase SYK, 1-[(3-methyl-1-{2-[(1,2,3-trimethyl-1H-indol-5-yl)amino]pyrimidin-4-yl}-1H-pyrazol-4-yl)methyl]azetidin-3-ol
Authors:Lee, B.I., Lee, S.J., Choi, J.-S.
Deposit date:2014-11-11
Release date:2015-10-21
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Highly potent and selective pyrazolylpyrimidines as Syk kinase inhibitors.
Bioorg.Med.Chem.Lett., 25, 2015
5C16
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MYOTUBULARIN-RELATED PROETIN 1
Descriptor:Myotubularin-related protein 1, PHOSPHATE ION
Authors:Lee, B.I., Bong, S.M.
Deposit date:2015-06-13
Release date:2016-04-27
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Crystal Structure of Human Myotubularin-Related Protein 1 Provides Insight into the Structural Basis of Substrate Specificity
Plos One, 11, 2016
4JX3
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CRYSTAL STRUCTURE OF PIM1 KINASE
Descriptor:Serine/threonine-protein kinase pim-1
Authors:Lee, S.J., Han, B.G., Cho, J.W., Choi, J.S., Lee, J.K., Song, H.J., Koh, J.S., Lee, B.I.
Deposit date:2013-03-27
Release date:2013-08-28
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of pim1 kinase in complex with a pyrido[4,3-d]pyrimidine derivative suggests a unique binding mode.
Plos One, 8, 2013
4JX7
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CRYSTAL STRUCTURE OF PIM1 KINASE IN COMPLEX WITH INHIBITOR 2-[(TRANS-4-AMINOCYCLOHEXYL)AMINO]-4-{[3-(TRIFLUOROMETHYL)PHENYL]AMINO}PYRIDO[4,3-D]PYRIMIDIN-5(6H)-ONE
Descriptor:Serine/threonine-protein kinase pim-1, PIM1 consensus peptide, 2-[(trans-4-aminocyclohexyl)amino]-4-{[3-(trifluoromethyl)phenyl]amino}pyrido[4,3-d]pyrimidin-5(6H)-one
Authors:Lee, S.J., Han, B.G., Cho, J.W., Choi, J.S., Lee, J.K., Song, H.J., Koh, J.S., Lee, B.I.
Deposit date:2013-03-27
Release date:2013-08-28
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of pim1 kinase in complex with a pyrido[4,3-d]pyrimidine derivative suggests a unique binding mode.
Plos One, 8, 2013
5Y5T
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CRYSTAL STRUCTURES OF SPLEEN TYROSINE KINASE IN COMPLEX WITH A NOVEL INHIBITOR
Descriptor:Tyrosine-protein kinase SYK, 2-[[(1S,2S)-2-azanylcyclohexyl]amino]-4-[(4-methylsulfonylphenyl)amino]-6H-pyrido[4,3-d]pyrimidin-5-one
Authors:Lee, S.J., Lee, B.I.
Deposit date:2017-08-09
Release date:2018-06-27
Last modified:2018-07-11
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structures of Spleen Tyrosine Kinase in Complex with Two Novel 4-Aminopyrido[4,3-d] Pyrimidine Derivative Inhibitors.
Mol. Cells, 41, 2018
5Y5U
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CRYSTAL STRUCTURES OF SPLEEN TYROSINE KINASE IN COMPLEX WITH A NOVEL INHIBITOR
Descriptor:Tyrosine-protein kinase SYK, 4-[(1-methylindazol-5-yl)amino]-2-(4-oxidanylpiperidin-1-yl)-8H-pyrido[4,3-d]pyrimidin-5-one
Authors:Lee, S.J., Lee, B.I.
Deposit date:2017-08-09
Release date:2018-06-27
Last modified:2018-07-11
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Crystal Structures of Spleen Tyrosine Kinase in Complex with Two Novel 4-Aminopyrido[4,3-d] Pyrimidine Derivative Inhibitors.
Mol. Cells, 41, 2018
3U0R
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HELICAL REPEAT STRUCTURE OF APOPTOSIS INHIBITOR 5 REVEALS PROTEIN-PROTEIN INTERACTION MODULES
Descriptor:Apoptosis inhibitor 5
Authors:Han, B.G., Kim, K.H., Jeong, K.C., Cho, J.W., Noh, K.H., Kim, T.W., Yoon, H.J., Suh, S.W., Lee, S.H., Lee, B.I.
Deposit date:2011-09-29
Release date:2012-02-22
Last modified:2013-07-10
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Helical repeat structure of apoptosis inhibitor 5 reveals protein-protein interaction modules.
J.Biol.Chem., 287, 2012
4XG2
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CRYSTAL STRUCTURE OF LIGAND-FREE SYK
Descriptor:Tyrosine-protein kinase SYK
Authors:Lee, S.J., Choi, J., Han, B.G., Song, H., Koh, J.S., Lee, B.I.
Deposit date:2014-12-30
Release date:2015-12-30
Last modified:2016-10-19
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Crystal structures of spleen tyrosine kinase in complex with novel inhibitors: structural insights for design of anticancer drugs
Febs J., 283, 2016
4XG3
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CRYSTAL STRUCTURE OF AN INHIBITOR-BOUND SYK
Descriptor:Tyrosine-protein kinase SYK, 4-{[5-fluoro-4-(3-{[(3R)-3-hydroxypyrrolidin-1-yl]methyl}-4-methyl-1H-pyrrol-1-yl)pyrimidin-2-yl]amino}-2,6-dimethylphenyl methanesulfonate
Authors:Lee, S.J., Choi, J., Han, B.G., Song, H., Koh, J.S., Lee, B.I.
Deposit date:2014-12-30
Release date:2015-12-30
Last modified:2016-10-19
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures of spleen tyrosine kinase in complex with novel inhibitors: structural insights for design of anticancer drugs
Febs J., 283, 2016
4XG4
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CRYSTAL STRUCTURE OF AN INHIBITOR-BOUND SYK
Descriptor:Tyrosine-protein kinase SYK, (3R)-1-{[1-(5-fluoro-2-{[4-(2-hydroxyethoxy)-3,5-dimethylphenyl]amino}pyrimidin-4-yl)-4-methyl-1H-pyrrol-3-yl]methyl}pyrrolidin-3-ol
Authors:Lee, S.J., Choi, J., Han, B.G., Song, H., Koh, J.S., Lee, B.I.
Deposit date:2014-12-30
Release date:2015-12-30
Last modified:2016-10-19
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures of spleen tyrosine kinase in complex with novel inhibitors: structural insights for design of anticancer drugs
Febs J., 283, 2016
4XG6
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CRYSTAL STRUCTURE OF AN INHIBITOR-BOUND SYK
Descriptor:Tyrosine-protein kinase SYK, 1-[(1-{2-[(3,5-dimethylphenyl)amino]pyrimidin-4-yl}-3-methyl-1H-pyrazol-4-yl)methyl]azetidin-3-ol
Authors:Lee, S.J., Choi, J., Han, B.G., Song, H., Koh, J.S., Lee, B.I.
Deposit date:2014-12-30
Release date:2015-12-30
Last modified:2016-10-19
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structures of spleen tyrosine kinase in complex with novel inhibitors: structural insights for design of anticancer drugs
Febs J., 283, 2016
4XG7
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CRYSTAL STRUCTURE OF AN INHIBITOR-BOUND SYK
Descriptor:Tyrosine-protein kinase SYK, 1-[(3-methyl-1-{2-[(1-methyl-1H-indazol-5-yl)amino]pyrimidin-4-yl}-1H-pyrazol-4-yl)methyl]azetidin-3-ol
Authors:Lee, S.J., Choi, J., Han, B.G., Song, H., Koh, J.S., Lee, B.I.
Deposit date:2014-12-30
Release date:2015-12-30
Last modified:2016-10-19
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Crystal structures of spleen tyrosine kinase in complex with novel inhibitors: structural insights for design of anticancer drugs
Febs J., 283, 2016
4XG8
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CRYSTAL STRUCTURE OF AN INHIBITOR-BOUND SYK
Descriptor:Tyrosine-protein kinase SYK, 1-[(1-{2-[(3-chloro-1-methyl-1H-indazol-5-yl)amino]pyrimidin-4-yl}-3-methyl-1H-pyrazol-4-yl)methyl]azetidin-3-ol
Authors:Lee, S.J., Choi, J., Han, B.G., Song, H., Koh, J.S., Lee, B.I.
Deposit date:2014-12-30
Release date:2015-12-30
Last modified:2016-10-19
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structures of spleen tyrosine kinase in complex with novel inhibitors: structural insights for design of anticancer drugs
Febs J., 283, 2016
4XG9
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CRYSTAL STRUCTURE OF AN INHIBITOR-BOUND SYK
Descriptor:Tyrosine-protein kinase SYK, 1-[(1-{2-[(3-chloro-1,2-dimethyl-1H-indol-5-yl)amino]pyrimidin-4-yl}-3-methyl-1H-pyrazol-4-yl)methyl]azetidin-3-ol
Authors:Lee, S.J., Choi, J., Han, B.G., Song, H., Koh, J.S., Lee, B.I.
Deposit date:2014-12-30
Release date:2015-12-30
Last modified:2016-10-19
Method:X-RAY DIFFRACTION (2.91 Å)
Cite:Crystal structures of spleen tyrosine kinase in complex with novel inhibitors: structural insights for design of anticancer drugs
Febs J., 283, 2016
5GHV
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CRYSTAL STRUCTURE OF AN INHIBITOR-BOUND SYK
Descriptor:Tyrosine-protein kinase SYK, 1-({1-[2-({3,5-dimethyl-4-[2-(pyrrolidin-1-yl)ethoxy]phenyl}amino)pyrimidin-4-yl]-4-methyl-1H-pyrrol-3-yl}methyl)azetidin-3-ol
Authors:Lee, S.J., Choi, J., Han, B.G., Song, H., Koh, J.S., Lee, B.I.
Deposit date:2016-06-20
Release date:2016-07-06
Last modified:2016-10-19
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structures of spleen tyrosine kinase in complex with novel inhibitors: structural insights for design of anticancer drugs
Febs J., 283, 2016
2P1B
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CRYSTAL STRUCTURE OF HUMAN NUCLEOPHOSMIN-CORE
Descriptor:Nucleophosmin
Authors:Lee, H.H., Kim, H.S., Kang, J.Y., Lee, B.I., Ha, J.Y., Yoon, H.J., Lim, S.O., Jung, G., Suh, S.W.
Deposit date:2007-03-03
Release date:2007-03-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Crystal structure of human nucleophosmin-core reveals plasticity of the pentamer-pentamer interface
Proteins, 69, 2007
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