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1WBD
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BU of 1wbd by Molmil
Crystal structure of E. coli DNA mismatch repair enzyme MutS, E38Q mutant, in complex with a G.T mismatch
Descriptor: 5'-D(*AP*CP*TP*GP*GP*TP*GP*CP*TP*TP *GP*GP*CP*AP*GP*CP*T)-3', 5'-D(*AP*GP*CP*TP*GP*CP*CP*AP*GP*GP *CP*AP*CP*CP*AP*GP*TP*G)-3', ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Natrajan, G, Georgijevic, D, Lebbink, J.H.G, Winterwerp, H.H.K, de Wind, N, Sixma, T.K.
Deposit date:2004-10-31
Release date:2006-01-18
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Dual Role of Muts Glutamate 38 in DNA Mismatch Discrimination and in the Authorization of Repair.
Embo J., 25, 2006
1WBB
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BU of 1wbb by Molmil
Crystal structure of E. coli DNA mismatch repair enzyme MutS, E38A mutant, in complex with a G.T mismatch
Descriptor: 5'-D(*AP*CP*TP*GP*GP*TP*GP*CP*TP*TP *GP*GP*CP*AP*GP*CP*T)-3', 5'-D(*AP*GP*CP*TP*GP*CP*CP*AP*GP*GP *CP*AP*CP*CP*AP*GP*TP*G)-3', ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Natrajan, G, Georgijevic, D, Lebbink, J.H.G, Winterwerp, H.H.K, de Wind, N, Sixma, T.K.
Deposit date:2004-10-31
Release date:2006-01-18
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Dual Role of Muts Glutamate 38 in DNA Mismatch Discrimination and in the Authorization of Repair.
Embo J., 25, 2006
1WB9
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BU of 1wb9 by Molmil
Crystal Structure of E. coli DNA Mismatch Repair enzyme MutS, E38T mutant, in complex with a G.T mismatch
Descriptor: 5'-D(*AP*CP*TP*GP*GP*TP*GP*CP*TP*TP *GP*GP*CP*AP*GP*CP*T)-3', 5'-D(*AP*GP*CP*TP*GP*CP*CP*AP*GP*GP *CP*AP*CP*CP*AP*GP*TP*G)-3', ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Natrajan, G, Georgijevic, D, Lebbink, J.H.G, Winterwerp, H.H.K, de Wind, N, Sixma, T.K.
Deposit date:2004-10-31
Release date:2006-01-18
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Dual Role of Muts Glutamate 38 in DNA Mismatch Discrimination and in the Authorization of Repair.
Embo J., 25, 2006
3ZLJ
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BU of 3zlj by Molmil
CRYSTAL STRUCTURE OF FULL-LENGTH E.COLI DNA MISMATCH REPAIR PROTEIN MUTS D835R MUTANT IN COMPLEX WITH GT MISMATCHED DNA
Descriptor: 5'-D(*AP*GP*CP*TP*GP*CP*CP*AP*GP*GP*CP*AP*CP*CP *AP*GP*TP*GP*TP*CP*AP)-3', 5'-D(*TP*GP*AP*CP*AP*CP*TP*GP*GP*TP*GP*CP*TP*TP *GP*GP*CP*AP*GP*CP*TP)-3', DNA MISMATCH REPAIR PROTEIN MUTS
Authors:Groothuizen, F.S, Fish, A, Petoukhov, M.V, Reumer, A, Manelyte, L, Winterwerp, H.H.K, Marinus, M.G, Lebbink, J.H.G, Svergun, D.I, Friedhoff, P, Sixma, T.K.
Deposit date:2013-02-01
Release date:2013-07-17
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Using Stable Muts Dimers and Tetramers to Quantitatively Analyze DNA Mismatch Recognition and Sliding Clamp Formation.
Nucleic Acids Res., 41, 2013
1B3B
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BU of 1b3b by Molmil
THERMOTOGA MARITIMA GLUTAMATE DEHYDROGENASE MUTANT N97D, G376K
Descriptor: PROTEIN (GLUTAMATE DEHYDROGENASE)
Authors:Knapp, S, Lebbink, J.H.G, Van Der Oost, J, Devos, W.M, Rice, D, Ladenstein, R.
Deposit date:1998-12-07
Release date:1999-12-08
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Engineering activity and stability of Thermotoga maritima glutamate dehydrogenase. I. Introduction of a six-residue ion-pair network in the hinge region.
J.Mol.Biol., 280, 1998
7P8V
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BU of 7p8v by Molmil
The structure of E. coli MutL bound to a 3' resected DNA end
Descriptor: DNA mismatch repair protein MutL, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Borsellini, A, Lamers, M.H.
Deposit date:2021-07-23
Release date:2022-06-29
Last modified:2022-08-31
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:MutL binds to 3' resected DNA ends and blocks DNA polymerase access.
Nucleic Acids Res., 50, 2022
2TMG
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BU of 2tmg by Molmil
THERMOTOGA MARITIMA GLUTAMATE DEHYDROGENASE MUTANT S128R, T158E, N117R, S160E
Descriptor: PROTEIN (GLUTAMATE DEHYDROGENASE)
Authors:Knapp, S, Lebbink, J.H.G, van der Oost, J, de Vos, W.M, Rice, D, Ladenstein, R.
Deposit date:1998-12-04
Release date:1999-12-08
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Engineering activity and stability of Thermotoga maritima glutamate dehydrogenase. II: construction of a 16-residue ion-pair network at the subunit interface.
J.Mol.Biol., 289, 1999
8HHM
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BU of 8hhm by Molmil
Cryo-EM structure of the Cas12m2-crRNA-target DNA ternary complex intermediate state
Descriptor: Cas12m2, DNA (36-MER), GUANOSINE-5'-MONOPHOSPHATE, ...
Authors:Omura, N.S, Nakagawa, R, Wu, Y.W, Sudfeld, C, Warren, V.R, Hirano, H, Kusakizako, T, Kise, Y, Lebbink, H.G.J, Itoh, Y, Oost, V.D.J, Nureki, O.
Deposit date:2022-11-16
Release date:2023-04-12
Last modified:2023-08-30
Method:ELECTRON MICROSCOPY (3.08 Å)
Cite:Mechanistic and evolutionary insights into a type V-M CRISPR-Cas effector enzyme.
Nat.Struct.Mol.Biol., 30, 2023
8HHL
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BU of 8hhl by Molmil
Cryo-EM structure of the Cas12m2-crRNA-target DNA full R-loop complex
Descriptor: Cas12m2, MAGNESIUM ION, NTS (36-MER), ...
Authors:Omura, N.S, Nakagawa, R, Wu, Y.W, Sudfeld, C, Warren, V.R, Hirano, H, Kusakizako, T, Kise, Y, Lebbink, H.G.J, Itoh, Y, Oost, V.D.J, Nureki, O.
Deposit date:2022-11-16
Release date:2023-04-12
Last modified:2023-08-30
Method:ELECTRON MICROSCOPY (2.87 Å)
Cite:Mechanistic and evolutionary insights into a type V-M CRISPR-Cas effector enzyme.
Nat.Struct.Mol.Biol., 30, 2023
8HIO
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BU of 8hio by Molmil
Cryo-EM structure of the Cas12m2-crRNA binary complex
Descriptor: Cas12m2, MAGNESIUM ION, RNA (56-MER), ...
Authors:Omura, N.S, Nakagawa, R, Wu, Y.W, Sudfeld, C, Warren, V.R, Hirano, H, Kusakizako, T, Kise, Y, Lebbink, H.G.J, Itoh, Y, Oost, V.D.J, Nureki, O.
Deposit date:2022-11-21
Release date:2023-04-12
Last modified:2023-08-30
Method:ELECTRON MICROSCOPY (3.73 Å)
Cite:Mechanistic and evolutionary insights into a type V-M CRISPR-Cas effector enzyme.
Nat.Struct.Mol.Biol., 30, 2023
5AKD
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BU of 5akd by Molmil
MutS in complex with the N-terminal domain of MutL - crystal form 3
Descriptor: DNA MISMATCH REPAIR PROTEIN MUTL, DNA MISMATCH REPAIR PROTEIN MUTS, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Groothuizen, F.S, Winkler, I, Cristovao, M, Fish, A, Winterwerp, H.H.K, Reumer, A, Marx, A.D, Hermans, N, Nicholls, R.A, Murshudov, G.N, Lebbink, J.H.G, Friedhoff, P, Sixma, T.K.
Deposit date:2015-03-03
Release date:2015-07-22
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (7.6 Å)
Cite:MutS/MutL crystal structure reveals that the MutS sliding clamp loads MutL onto DNA.
Elife, 4, 2015
5AKB
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BU of 5akb by Molmil
MutS in complex with the N-terminal domain of MutL - crystal form 1
Descriptor: DNA MISMATCH REPAIR PROTEIN MUTL, DNA MISMATCH REPAIR PROTEIN MUTS, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Groothuizen, F.S, Winkler, I, Cristovao, M, Fish, A, Winterwerp, H.H.K, Reumer, A, Marx, A.D, Hermans, N, Nicholls, R.A, Murshudov, G.N, Lebbink, J.H.G, Friedhoff, P, Sixma, T.K.
Deposit date:2015-03-03
Release date:2015-07-22
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (4.71 Å)
Cite:MutS/MutL crystal structure reveals that the MutS sliding clamp loads MutL onto DNA.
Elife, 4, 2015
5AKC
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BU of 5akc by Molmil
MutS in complex with the N-terminal domain of MutL - crystal form 2
Descriptor: DNA MISMATCH REPAIR PROTEIN MUTL, DNA MISMATCH REPAIR PROTEIN MUTS, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Groothuizen, F.S, Winkler, I, Cristovao, M, Fish, A, Winterwerp, H.H.K, Reumer, A, Marx, A.D, Hermans, N, Nicholls, R.A, Murshudov, G.N, Lebbink, J.H.G, Friedhoff, P, Sixma, T.K.
Deposit date:2015-03-03
Release date:2015-07-22
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (6.6 Å)
Cite:MutS/MutL crystal structure reveals that the MutS sliding clamp loads MutL onto DNA.
Elife, 4, 2015
7AI7
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BU of 7ai7 by Molmil
MutS in Intermediate state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA (5'-D(P*CP*TP*TP*AP*GP*CP*TP*TP*AP*GP*GP*AP*TP*C)-3'), DNA (5'-D(P*GP*AP*TP*CP*CP*TP*AP*AP*CP*TP*AP*AP*G)-3'), ...
Authors:Fernandez-Leiro, R, Bhairosing-Kok, D, Sixma, T.K, Lamers, M.H.
Deposit date:2020-09-26
Release date:2021-03-31
Last modified:2021-04-28
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:The selection process of licensing a DNA mismatch for repair.
Nat.Struct.Mol.Biol., 28, 2021
7AI6
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BU of 7ai6 by Molmil
MutS in mismatch bound state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA (25-MER), DNA mismatch repair protein MutS
Authors:Fernandez-Leiro, R, Bhairosing-Kok, D, Sixma, T.K, Lamers, M.H.
Deposit date:2020-09-26
Release date:2021-03-31
Last modified:2021-04-28
Method:ELECTRON MICROSCOPY (6.9 Å)
Cite:The selection process of licensing a DNA mismatch for repair.
Nat.Struct.Mol.Biol., 28, 2021
7AI5
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BU of 7ai5 by Molmil
MutS in Scanning state
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, DNA (5'-D(P*CP*GP*GP*TP*AP*CP*CP*CP*AP*AP*TP*TP*CP*GP*CP*CP*CP*TP*AP*TP*AP*G)-3'), DNA (5'-D(P*CP*TP*AP*TP*AP*GP*GP*GP*CP*GP*AP*AP*TP*TP*GP*GP*GP*TP*AP*CP*CP*G)-3'), ...
Authors:Fernandez-Leiro, R, Bhairosing-Kok, D, Sixma, T.K, Lamers, M.H.
Deposit date:2020-09-26
Release date:2021-03-31
Last modified:2021-04-28
Method:ELECTRON MICROSCOPY (5 Å)
Cite:The selection process of licensing a DNA mismatch for repair.
Nat.Struct.Mol.Biol., 28, 2021
7AIC
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BU of 7aic by Molmil
MutS-MutL in clamp state (kinked clamp domain)
Descriptor: DNA (30-MER), DNA mismatch repair protein MutL, DNA mismatch repair protein MutS, ...
Authors:Fernandez-Leiro, R, Bhairosing-Kok, D, Sixma, T.K, Lamers, M.H.
Deposit date:2020-09-26
Release date:2021-03-31
Last modified:2021-04-28
Method:ELECTRON MICROSCOPY (5 Å)
Cite:The selection process of licensing a DNA mismatch for repair.
Nat.Struct.Mol.Biol., 28, 2021
7AIB
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BU of 7aib by Molmil
MutS-MutL in clamp state
Descriptor: DNA (30-MER), DNA mismatch repair protein MutL, DNA mismatch repair protein MutS, ...
Authors:Fernandez-Leiro, R, Bhairosing-Kok, D, Sixma, T.K, Lamers, M.H.
Deposit date:2020-09-26
Release date:2021-03-31
Last modified:2021-04-28
Method:ELECTRON MICROSCOPY (4.7 Å)
Cite:The selection process of licensing a DNA mismatch for repair.
Nat.Struct.Mol.Biol., 28, 2021

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