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1FNF
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BU of 1fnf by Molmil
FRAGMENT OF HUMAN FIBRONECTIN ENCOMPASSING TYPE-III REPEATS 7 THROUGH 10
Descriptor: FIBRONECTIN
Authors:Leahy, D.J, Aukhil, I, Erickson, H.P.
Deposit date:1995-09-30
Release date:1996-01-29
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:2.0 A crystal structure of a four-domain segment of human fibronectin encompassing the RGD loop and synergy region.
Cell(Cambridge,Mass.), 84, 1996
1CD8
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BU of 1cd8 by Molmil
CRYSTAL STRUCTURE OF A SOLUBLE FORM OF THE HUMAN T CELL CO-RECEPTOR CD8 AT 2.6 ANGSTROMS RESOLUTION
Descriptor: SULFATE ION, T CELL CORECEPTOR CD8
Authors:Leahy, D.J, Axel, R, Hendrickson, W.A.
Deposit date:1992-01-16
Release date:1994-01-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of a soluble form of the human T cell coreceptor CD8 at 2.6 A resolution.
Cell(Cambridge,Mass.), 68, 1992
1TEN
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BU of 1ten by Molmil
STRUCTURE OF A FIBRONECTIN TYPE III DOMAIN FROM TENASCIN PHASED BY MAD ANALYSIS OF THE SELENOMETHIONYL PROTEIN
Descriptor: TENASCIN
Authors:Leahy, D.J, Hendrickson, W.A, Aukhil, I, Erickson, H.P.
Deposit date:1992-08-28
Release date:1993-10-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of a fibronectin type III domain from tenascin phased by MAD analysis of the selenomethionyl protein.
Science, 258, 1992
1BAF
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BU of 1baf by Molmil
2.9 ANGSTROMS RESOLUTION STRUCTURE OF AN ANTI-DINITROPHENYL-SPIN-LABEL MONOCLONAL ANTIBODY FAB FRAGMENT WITH BOUND HAPTEN
Descriptor: IGG1-KAPPA AN02 FAB (HEAVY CHAIN), IGG1-KAPPA AN02 FAB (LIGHT CHAIN), N-(2-AMINO-ETHYL)-4,6-DINITRO-N'-(2,2,6,6-TETRAMETHYL-1-OXY-PIPERIDIN-4-YL)-BENZENE-1,3-DIAMINE
Authors:Leahy, D.J, Brunger, A.T, Fox, R.O, Hynes, T.R.
Deposit date:1992-01-16
Release date:1994-01-31
Last modified:2013-09-18
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:2.9 A resolution structure of an anti-dinitrophenyl-spin-label monoclonal antibody Fab fragment with bound hapten.
J.Mol.Biol., 221, 1991
1ZOP
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BU of 1zop by Molmil
CD11A I-DOMAIN WITH BOUND MAGNESIUM ION
Descriptor: CHLORIDE ION, I-DOMAIN FRAGMENT OF LFA-1, MANGANESE (II) ION
Authors:Leahy, D.J, Qu, A.
Deposit date:1996-06-21
Release date:1996-12-07
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:The role of the divalent cation in the structure of the I domain from the CD11a/CD18 integrin.
Structure, 4, 1996
1ZOO
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BU of 1zoo by Molmil
CD11A I-DOMAIN WITH BOUND MAGNESIUM ION
Descriptor: CHLORIDE ION, LEUKOCYTE ADHESION GLYCOPROTEIN, MAGNESIUM ION
Authors:Leahy, D.J, Qu, A.
Deposit date:1996-06-21
Release date:1996-12-07
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (3 Å)
Cite:The role of the divalent cation in the structure of the I domain from the CD11a/CD18 integrin.
Structure, 4, 1996
1ZON
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BU of 1zon by Molmil
CD11A I-DOMAIN WITHOUT BOUND CATION
Descriptor: LEUKOCYTE ADHESION GLYCOPROTEIN
Authors:Leahy, D.J, Qu, A.
Deposit date:1996-06-20
Release date:1996-12-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:The role of the divalent cation in the structure of the I domain from the CD11a/CD18 integrin.
Structure, 4, 1996
1LFA
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BU of 1lfa by Molmil
CD11A I-DOMAIN WITH BOUND MN++
Descriptor: CD11A, CHLORIDE ION, MANGANESE (II) ION
Authors:Leahy, D.J, Qu, A.
Deposit date:1995-09-08
Release date:1996-01-29
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the I-domain from the CD11a/CD18 (LFA-1, alpha L beta 2) integrin.
Proc.Natl.Acad.Sci.USA, 92, 1995
1M6B
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BU of 1m6b by Molmil
Structure of the HER3 (ERBB3) Extracellular Domain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Receptor protein-tyrosine kinase erbB-3, ...
Authors:Leahy, D.J, Cho, H.-S.
Deposit date:2002-07-15
Release date:2002-08-02
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of the extracellular region of HER3 reveals an interdomain tether.
Science, 297, 2002
6JFV
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BU of 6jfv by Molmil
The crystal structure of 2B-2B complex from keratins 5 and 14 (C367A mutant of K14)
Descriptor: Keratin, type I cytoskeletal 14, type II cytoskeletal 5
Authors:Kim, M.S, Lee, C.H, Coulombe, P.A, Leahy, D.J.
Deposit date:2019-02-12
Release date:2020-01-22
Last modified:2022-03-23
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure-Function Analyses of a Keratin Heterotypic Complex Identify Specific Keratin Regions Involved in Intermediate Filament Assembly.
Structure, 28, 2020
1AT0
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BU of 1at0 by Molmil
17-kDA fragment of hedgehog C-terminal autoprocessing domain
Descriptor: 17-HEDGEHOG
Authors:Hall, T.M.T, Porter, J.A, Young, K.E, Koonin, E.V, Beachy, P.A, Leahy, D.J.
Deposit date:1997-08-15
Release date:1997-11-12
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of a Hedgehog autoprocessing domain: homology between Hedgehog and self-splicing proteins.
Cell(Cambridge,Mass.), 91, 1997
1DDV
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BU of 1ddv by Molmil
CRYSTAL STRUCTURE OF THE HOMER EVH1 DOMAIN WITH BOUND MGLUR PEPTIDE
Descriptor: GLGF-DOMAIN PROTEIN HOMER, METABOTROPIC GLUTAMATE RECEPTOR MGLUR5
Authors:Beneken, J, Tu, J.C, Xiao, B, Worley, P.F, Leahy, D.J.
Deposit date:1999-11-11
Release date:2000-05-10
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of the Homer EVH1 domain-peptide complex reveals a new twist in polyproline recognition.
Neuron, 26, 2000
1DDW
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BU of 1ddw by Molmil
HOMER EVH1 DOMAIN UNLIGANDED
Descriptor: GLGF-DOMAIN PROTEIN HOMER
Authors:Beneken, J, Tu, J.C, Xiao, B, Worley, P.F, Leahy, D.J.
Deposit date:1999-11-11
Release date:2000-05-10
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of the Homer EVH1 domain-peptide complex reveals a new twist in polyproline recognition.
Neuron, 26, 2000
1S78
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BU of 1s78 by Molmil
Insights into ErbB signaling from the structure of the ErbB2-pertuzumab complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Pertuzumab Fab heavy chain, ...
Authors:Franklin, M.C, Carey, K.D, Vajdos, F.F, Leahy, D.J, de Vos, A.M, Sliwkowski, M.X.
Deposit date:2004-01-29
Release date:2004-04-27
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Insights into ErbB signaling from the structure of the ErbB2-pertuzumab complex.
Cancer Cell, 5, 2004
4PFJ
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BU of 4pfj by Molmil
The structure of bi-acetylated SAHH
Descriptor: ADENOSINE, Adenosylhomocysteinase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Kavran, J.M, Wang, Y, Cole, P.A, Leahy, D.J.
Deposit date:2014-04-29
Release date:2014-10-01
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Regulation of s-adenosylhomocysteine hydrolase by lysine acetylation.
J.Biol.Chem., 289, 2014
4PGF
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BU of 4pgf by Molmil
The structure of mono-acetylated SAHH
Descriptor: ADENOSINE, Adenosylhomocysteinase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Kavran, J.M, Wang, Y, Cole, P.A, Leahy, D.J.
Deposit date:2014-05-01
Release date:2014-10-01
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Regulation of s-adenosylhomocysteine hydrolase by lysine acetylation.
J.Biol.Chem., 289, 2014
3U7U
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BU of 3u7u by Molmil
Crystal structure of extracellular region of human epidermal growth factor receptor 4 in complex with neuregulin-1 beta
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Neuregulin 1, Receptor tyrosine-protein kinase erbB-4
Authors:Liu, P, Cleveland IV, T.E, Bouyain, S, Longo, P.A, Leahy, D.J.
Deposit date:2011-10-14
Release date:2012-08-29
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.03 Å)
Cite:A single ligand is sufficient to activate EGFR dimers.
Proc.Natl.Acad.Sci.USA, 109, 2012
3TNU
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BU of 3tnu by Molmil
Heterocomplex of coil 2B domains of human intermediate filament proteins, keratin 5 (KRT5) and keratin 14 (KRT14)
Descriptor: Keratin, type I cytoskeletal 14, type II cytoskeletal 5
Authors:Lee, C.H, Kim, M.S, Leahy, D.J, Coulombe, P.A.
Deposit date:2011-09-02
Release date:2012-06-20
Last modified:2012-08-01
Method:X-RAY DIFFRACTION (3.005 Å)
Cite:Structural basis for heteromeric assembly and perinuclear organization of keratin filaments.
Nat.Struct.Mol.Biol., 19, 2012
3U2P
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BU of 3u2p by Molmil
Crystal structure of N-terminal three extracellular domains of ErbB4/Her4
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Receptor tyrosine-protein kinase erbB-4
Authors:Liu, P, Bouyain, S, Elgenbrot, C, Leahy, D.J.
Deposit date:2011-10-04
Release date:2011-11-09
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.57 Å)
Cite:The ErbB4 extracellular region retains a tethered-like conformation in the absence of the tether.
Protein Sci., 21, 2012
3U9U
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BU of 3u9u by Molmil
Crystal Structure of Extracellular Domain of Human ErbB4/Her4 in complex with the Fab fragment of mAb1479
Descriptor: Fab Heavy Chain, Fab Light Chain, Receptor tyrosine-protein kinase erbB-4
Authors:Hollmen, M, Liu, P, Wildiers, H, Reinvall, I, Vandorpe, T, Smeets, A, Deraedt, K, Vahlberg, T, Joensuu, H, Leahy, D.J, Schoffski, P, Elenius, K.
Deposit date:2011-10-19
Release date:2012-10-31
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.42 Å)
Cite:Proteolytic processing of ErbB4 in breast cancer.
Plos One, 7, 2012
2OGB
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BU of 2ogb by Molmil
Crystal structure of the C-terminal domain of mouse Nrdp1
Descriptor: GLYCEROL, RING finger protein 41, THIOCYANATE ION
Authors:Bouyain, S, Leahy, D.J.
Deposit date:2007-01-05
Release date:2007-01-16
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structure-based mutagenesis of the substrate-recognition domain of Nrdp1/FLRF identifies the binding site for the receptor tyrosine kinase ErbB3.
Protein Sci., 16, 2007
2ORX
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BU of 2orx by Molmil
Structural Basis for Ligand Binding and Heparin Mediated Activation of Neuropilin
Descriptor: Neuropilin-1
Authors:Vander Kooi, C.W, Jusino, M.A, Perman, B, Neau, D.B, Bellamy, H.D, Leahy, D.J.
Deposit date:2007-02-05
Release date:2007-04-03
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis for ligand and heparin binding to neuropilin B domains
Proc.Natl.Acad.Sci.Usa, 104, 2007
2ORZ
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BU of 2orz by Molmil
Structural Basis for Ligand Binding and Heparin Mediated Activation of Neuropilin
Descriptor: Neuropilin-1, Tuftsin
Authors:Vander Kooi, C.W, Jusino, M.A, Perman, B, Neau, D.B, Bellamy, H.D, Leahy, D.J.
Deposit date:2007-02-05
Release date:2007-04-03
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural basis for ligand and heparin binding to neuropilin B domains.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2IBG
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BU of 2ibg by Molmil
Crystal Structure of Hedgehog Bound to the FNIII Domains of Ihog
Descriptor: CG9211-PA, PHOSPHATE ION, Protein hedgehog
Authors:McLellan, J.S, Leahy, D.J.
Deposit date:2006-09-11
Release date:2006-10-24
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of a heparin-dependent complex of Hedgehog and Ihog.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2IBB
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BU of 2ibb by Molmil
Crystal Structure of the First and Second FNIII Domains of Ihog
Descriptor: CG9211-PA, SULFATE ION
Authors:McLellan, J.S, Leahy, D.J.
Deposit date:2006-09-11
Release date:2006-10-24
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of a heparin-dependent complex of Hedgehog and Ihog.
Proc.Natl.Acad.Sci.Usa, 103, 2006

 

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