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4DG6
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BU of 4dg6 by Molmil
Crystal structure of domains 1 and 2 of LRP6
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Low-density lipoprotein receptor-related protein 6, PHOSPHATE ION
Authors:Ceska, T.A, Doyle, C, Slocombe, P.
Deposit date:2012-01-25
Release date:2012-06-13
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Characterization of the interaction of sclerostin with the LRP family of Wnt co-receptors
To be Published
3F66
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BU of 3f66 by Molmil
Human c-Met Kinase in complex with quinoxaline inhibitor
Descriptor: 3-[3-(4-methylpiperazin-1-yl)-7-(trifluoromethyl)quinoxalin-5-yl]phenol, GAMMA-BUTYROLACTONE, Hepatocyte growth factor receptor, ...
Authors:Meier, C, Ceska, T.
Deposit date:2008-11-05
Release date:2008-12-23
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Discovery of a novel series of quinoxalines as inhibitors of c-Met kinase.
Bioorg.Med.Chem.Lett., 19, 2009
2WD1
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BU of 2wd1 by Molmil
Human c-Met Kinase in complex with azaindole inhibitor
Descriptor: 1-[(2-NITROPHENYL)SULFONYL]-1H-PYRROLO[3,2-B]PYRIDINE-6-CARBOXAMIDE, GAMMA-BUTYROLACTONE, HEPATOCYTE GROWTH FACTOR RECEPTOR
Authors:Porter, J, Lumb, S, Franklin, R.J, Gascon-Simorte, J.M, Calmiano, M, Le Riche, K, Lallemand, B, Keyaerts, J, Edwards, H, Maloney, A, Delgado, J, King, L, Foley, A, Lecomte, F, Reuberson, J, Meier, C, Batchelor, M.
Deposit date:2009-03-19
Release date:2009-04-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Discovery of 4-Azaindoles as Novel Inhibitors of C- met Kinase.
Bioorg.Med.Chem.Lett., 19, 2009

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