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2HYI
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STRUCTURE OF THE HUMAN EXON JUNCTION COMPLEX WITH A TRAPPED DEAD-BOX HELICASE BOUND TO RNA
Descriptor:5'-R(*UP*UP*UP*UP*UP*U)-3', Protein mago nashi homolog, RNA-binding protein 8A, ...
Authors:Andersen, C.B.F., Le Hir, H., Andersen, G.R.
Deposit date:2006-08-06
Release date:2006-08-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of the exon junction core complex with a trapped DEAD-box ATPase bound to RNA.
Science, 313, 2006
2XB2
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CRYSTAL STRUCTURE OF THE CORE MAGO-Y14-EIF4AIII-BARENTSZ-UPF3B ASSEMBLY SHOWS HOW THE EJC IS BRIDGED TO THE NMD MACHINERY
Descriptor:EUKARYOTIC INITIATION FACTOR 4A-III, PROTEIN MAGO NASHI HOMOLOG, RNA-BINDING PROTEIN 8A, ...
Authors:Buchwald, G., Ebert, J., Basquin, C., Sauliere, J., Jayachandran, U., Bono, F., Le Hir, H., Conti, E.
Deposit date:2010-04-03
Release date:2010-05-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Insights Into the Recruitment of the Nmd Machinery from the Crystal Structure of a Core Ejc-Upf3B Complex.
Proc.Natl.Acad.Sci.USA, 107, 2010
2XZL
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UPF1-RNA COMPLEX
Descriptor:ATP-DEPENDENT HELICASE NAM7, 5- R(*UP*UP*UP*UP*UP*UP*UP*UP*U) -3, ZINC ION, ...
Authors:Chakrabarti, S., Jayachandran, U., Bonneau, F., Fiorini, F., Basquin, C., Domcke, S., Le Hir, H., Conti, E.
Deposit date:2010-11-26
Release date:2011-03-30
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Molecular Mechanisms for the RNA-Dependent ATPase Activity of Upf1 and its Regulation by Upf2.
Mol.Cell, 41, 2011
2XZO
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UPF1 HELICASE - RNA COMPLEX
Descriptor:REGULATOR OF NONSENSE TRANSCRIPTS 1, 5'-R(*UP*UP*UP*UP*UP*UP*UP)-3', PENTAETHYLENE GLYCOL, ...
Authors:Chakrabarti, S., Jayachandran, U., Bonneau, F., Fiorini, F., Basquin, C., Domcke, S., Le Hir, H., Conti, E.
Deposit date:2010-11-26
Release date:2011-03-30
Last modified:2017-07-12
Method:X-RAY DIFFRACTION (2.395 Å)
Cite:Molecular Mechanisms for the RNA-Dependent ATPase Activity of Upf1 and its Regulation by Upf2.
Mol.Cell, 41, 2011
2XZP
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UPF1 HELICASE
Descriptor:REGULATOR OF NONSENSE TRANSCRIPTS 1, GLYCEROL, MALONATE ION
Authors:Chakrabarti, S., Jayachandran, U., Bonneau, F., Fiorini, F., Basquin, C., Domcke, S., Le Hir, H., Conti, E.
Deposit date:2010-11-26
Release date:2011-03-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.72 Å)
Cite:Molecular Mechanisms for the RNA-Dependent ATPase Activity of Upf1 and its Regulation by Upf2.
Mol.Cell, 41, 2011
4A6Q
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CRYSTAL STRUCTURE OF MOUSE SAP18 RESIDUES 6-143
Descriptor:HISTONE DEACETYLASE COMPLEX SUBUNIT SAP18, ISOPROPYL ALCOHOL, (4S)-2-METHYL-2,4-PENTANEDIOL
Authors:Murachelli, A.G., Ebert, J., Basquin, C., Le Hir, H., Conti, E.
Deposit date:2011-11-08
Release date:2012-03-07
Last modified:2015-03-18
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The Structure of the Asap Core Complex Reveals the Existence of a Pinin-Containing Psap Complex
Nat.Struct.Mol.Biol., 19, 2012
4A8X
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STRUCTURE OF THE CORE ASAP COMPLEX
Descriptor:RNA-BINDING PROTEIN WITH SERINE-RICH DOMAIN 1, HOOK-LIKE, ISOFORM A, ...
Authors:Murachelli, A.G., Ebert, J., Basquin, C., Le Hir, H., Conti, E.
Deposit date:2011-11-21
Release date:2012-03-07
Last modified:2012-04-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The Structure of the Asap Core Complex Reveals the Existence of a Pinin-Containing Psap Complex
Nat.Struct.Mol.Biol., 19, 2012
4A90
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CRYSTAL STRUCTURE OF MOUSE SAP18 RESIDUES 1-143
Descriptor:HISTONE DEACETYLASE COMPLEX SUBUNIT SAP18, GLYCEROL
Authors:Murachelli, A.G., Ebert, J., Basquin, C., Le Hir, H., Conti, E.
Deposit date:2011-11-22
Release date:2012-03-07
Last modified:2012-04-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The Structure of the Asap Core Complex Reveals the Existence of a Pinin-Containing Psap Complex
Nat.Struct.Mol.Biol., 19, 2012
2HXY
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CRYSTAL STRUCTURE OF HUMAN APO-EIF4AIII
Descriptor:Probable ATP-dependent RNA helicase DDX48
Authors:Johansen, J.S., Andersen, G.R.
Deposit date:2006-08-04
Release date:2006-08-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structure of the exon junction core complex with a trapped DEAD-box ATPase bound to RNA.
Science, 313, 2006
3EX7
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THE CRYSTAL STRUCTURE OF EJC IN ITS TRANSITION STATE
Descriptor:Protein mago nashi homolog, RNA-binding protein 8A, Eukaryotic initiation factor 4A-III, ...
Authors:Andersen, G.R., Nielsen, K.H.
Deposit date:2008-10-16
Release date:2008-12-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.301 Å)
Cite:Mechanism of ATP turnover inhibition in the EJC
Rna, 15, 2009
4C9B
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CRYSTAL STRUCTURE OF EIF4AIII-CWC22 COMPLEX
Descriptor:EUKARYOTIC INITIATION FACTOR 4A-III, PRE-MRNA-SPLICING FACTOR CWC22 HOMOLOG, PHOSPHATE ION, ...
Authors:Buchwald, G., Schuessler, S., Basquin, C., LeHir, H., Conti, E.
Deposit date:2013-10-02
Release date:2013-11-13
Last modified:2013-12-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of the Human Eif4Aiii-Cwc22 Complex Shows How a Dead-Box Protein is Inhibited by a Mif4G Domain
Proc.Natl.Acad.Sci.USA, 110, 2013
6EJ5
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A CONSERVED STRUCTURAL ELEMENT IN THE RNA HELICASE UPF1 REGULATES ITS CATALYTIC ACTIVITY IN AN ISOFORM-SPECIFIC MANNER
Descriptor:Regulator of nonsense transcripts 1
Authors:Gowravaram, M., Bonneau, F., Maciej, V.D., Chakrabarti, S.
Deposit date:2017-09-20
Release date:2018-01-24
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (3.34 Å)
Cite:A conserved structural element in the RNA helicase UPF1 regulates its catalytic activity in an isoform-specific manner.
Nucleic Acids Res., 46, 2018