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2Y2Z
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LIGAND-FREE FORM OF TETR-LIKE REPRESSOR SIMR
Descriptor:PUTATIVE REPRESSOR SIMREG2
Authors:Le, T.B.K., Stevenson, C.E.M., Fiedler, H.-P., Maxwell, A., Lawson, D.M., Buttner, M.J.
Deposit date:2010-12-17
Release date:2011-03-09
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structures of the Tetr-Like Simocyclinone Efflux Pump Repressor, Simr, and the Mechanism of Ligand-Mediated Derepression.
J.Mol.Biol., 408, 2011
2Y30
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SIMOCYCLINONE D8 BOUND FORM OF TETR-LIKE REPRESSOR SIMR
Descriptor:PUTATIVE REPRESSOR SIMREG2, SIMOCYCLINONE D8, CHLORIDE ION
Authors:Le, T.B.K., Stevenson, C.E.M., Fiedler, H.-P., Maxwell, A., Lawson, D.M., Buttner, M.J.
Deposit date:2010-12-17
Release date:2011-03-09
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structures of the Tetr-Like Simocyclinone Efflux Pump Repressor, Simr, and the Mechanism of Ligand-Mediated Derepression.
J.Mol.Biol., 408, 2011
2Y31
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SIMOCYCLINONE C4 BOUND FORM OF TETR-LIKE REPRESSOR SIMR
Descriptor:PUTATIVE REPRESSOR SIMREG2, SIMOCYCLINONE C4, PENTAETHYLENE GLYCOL, ...
Authors:Le, T.B.K., Stevenson, C.E.M., Fiedler, H.-P., Maxwell, A., Lawson, D.M., Buttner, M.J.
Deposit date:2010-12-17
Release date:2011-03-09
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structures of the Tetr-Like Simocyclinone Efflux Pump Repressor, Simr, and the Mechanism of Ligand-Mediated Derepression.
J.Mol.Biol., 408, 2011
3ZQL
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DNA-BOUND FORM OF TETR-LIKE REPRESSOR SIMR
Descriptor:PUTATIVE REPRESSOR SIMREG2, 5'-D(*DTP*TP*CP*GP*TP*AP*CP*GP*CP*CP*GP*TP*AP*DCP *GP*AP*A)-3', 5'-D(*DTP*TP*CP*GP*TP*AP*CP*GP*GP*CP*GP*TP*AP*DCP *GP*AP*A)-3'
Authors:Le, T.B.K., Schumacher, M.A., Lawson, D.M., Brennan, R.G., Buttner, M.J.
Deposit date:2011-06-10
Release date:2011-08-31
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (2.99 Å)
Cite:The Crystal Structure of the Tetr Family Transcriptional Repressor Simr Bound to DNA and the Role of a Flexible N-Terminal Extension in Minor Groove Binding.
Nucleic Acids Res., 39, 2011
2Y3P
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CRYSTAL STRUCTURE OF N-TERMINAL DOMAIN OF GYRA WITH THE ANTIBIOTIC SIMOCYCLINONE D8
Descriptor:DNA GYRASE SUBUNIT A, MAGNESIUM ION, SIMOCYCLINONE D8
Authors:Edwards, M.J., Flatman, R.H., Mitchenall, L.A., Stevenson, C.E.M., Le, T.B.K., Clarke, T.A., McKay, A.R., Fiedler, H.-P., Buttner, M.J., Lawson, D.M., Maxwell, A.
Deposit date:2010-12-22
Release date:2010-12-29
Last modified:2017-07-12
Method:X-RAY DIFFRACTION (2.62 Å)
Cite:A Crystal Structure of the Bifunctional Antibiotic Simocyclinone D8, Bound to DNA Gyrase.
Science, 326, 2009
3ZPL
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CRYSTAL STRUCTURE OF SCO3205, A MARR FAMILY TRANSCRIPTIONAL REGULATOR FROM STREPTOMYCES COELICOLOR, IN COMPLEX WITH DNA
Descriptor:PUTATIVE MARR-FAMILY TRANSCRIPTIONAL REPRESSOR, 5'-D(*AP*AP*AP*GP*AP*TP*TP*GP*AP*GP*AP*TP*CP*TP *CP*AP*AP*TP*CP*TP*TP*DT)-3', PHOSPHATE ION
Authors:Stevenson, C.E.M., Assaad, A., Lawson, D.M.
Deposit date:2013-02-28
Release date:2013-07-17
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Investigation of DNA Sequence Recognition by a Streptomycete Marr Family Transcriptional Regulator Through Surface Plasmon Resonance and X-Ray Crystallography.
Nucleic Acids Res., 41, 2013
6AMA
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STRUCTURE OF S. COELICOLOR/S. VENEZUELAE BLDC-SMEA-SSFA COMPLEX TO 3.09 ANGSTROM
Descriptor:Putative DNA-binding protein, DNA (99-MER)
Authors:Schumacher, M.A.
Deposit date:2017-08-09
Release date:2018-03-28
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (3.09 Å)
Cite:The MerR-like protein BldC binds DNA direct repeats as cooperative multimers to regulate Streptomyces development.
Nat Commun, 9, 2018
6AMK
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STRUCTURE OF STREPTOMYCES VENEZUELAE BLDC-WHII OPT COMPLEX
Descriptor:Putative DNA-binding protein, DNA (5'-D(*TP*TP*CP*AP*AP*TP*TP*CP*GP*GP*GP*TP*AP*AP*TP*TP*CP*GP*GP*GP*CP*A)-3'), DNA (5'-D(*AP*AP*TP*GP*TP*CP*CP*GP*AP*AP*TP*TP*AP*CP*CP*CP*GP*AP*AP*TP*TP*G)-3')
Authors:Schumacher, M.A.
Deposit date:2017-08-09
Release date:2018-03-28
Last modified:2018-11-07
Method:X-RAY DIFFRACTION (3.288 Å)
Cite:The MerR-like protein BldC binds DNA direct repeats as cooperative multimers to regulate Streptomyces development.
Nat Commun, 9, 2018