Author results

1FDY
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N-ACETYLNEURAMINATE LYASE IN COMPLEX WITH HYDROXYPYRUVATE
Descriptor:N-ACETYLNEURAMINATE LYASE, 3-HYDROXYPYRUVIC ACID
Authors:Lawrence, M.C., Barbosa, J.A.R.G., Smith, B.J., Hall, N.E., Pilling, P.A., Ooi, H.C., Marcuccio, S.M.
Deposit date:1996-07-08
Release date:1997-10-22
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structure and mechanism of a sub-family of enzymes related to N-acetylneuraminate lyase.
J.Mol.Biol., 266, 1997
1FDZ
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N-ACETYLNEURAMINATE LYASE IN COMPLEX WITH PYRUVATE VIA BOROHYDRIDE REDUCTION
Descriptor:N-ACETYLNEURAMINATE LYASE, PYRUVIC ACID
Authors:Lawrence, M.C., Barbosa, J.A.R.G., Smith, B.J., Hall, N.E., Pilling, P.A., Ooi, H.C., Marcuccio, S.M.
Deposit date:1996-07-08
Release date:1997-10-22
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure and mechanism of a sub-family of enzymes related to N-acetylneuraminate lyase.
J.Mol.Biol., 266, 1997
1PSZ
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PNEUMOCOCCAL SURFACE ANTIGEN PSAA
Descriptor:PROTEIN (SURFACE ANTIGEN PSAA), ZINC ION
Authors:Lawrence, M.C., Pilling, P.A., Epa, V.C., Berry, A.M., Ogunniyi, A.D., Paton, J.C.
Deposit date:1998-10-13
Release date:2000-04-19
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:The crystal structure of pneumococcal surface antigen PsaA reveals a metal-binding site and a novel structure for a putative ABC-type binding protein.
Structure, 6, 1998
2PHL
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THE STRUCTURE OF PHASEOLIN AT 2.2 ANGSTROMS RESOLUTION: IMPLICATIONS FOR A COMMON VICILIN(SLASH)LEGUMIN STRUCTURE AND THE GENETIC ENGINEERING OF SEED STORAGE PROTEINS
Descriptor:PHASEOLIN, N-ACETYL-D-GLUCOSAMINE, PHOSPHATE ION
Authors:Lawrence, M.C., Izard, T., Beuchat, M., Blagrove, R.J., Colman, P.M.
Deposit date:1994-07-07
Release date:1994-09-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of phaseolin at 2.2 A resolution. Implications for a common vicilin/legumin structure and the genetic engineering of seed storage proteins.
J.Mol.Biol., 238, 1994
1PHS
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THE THREE-DIMENSIONAL STRUCTURE OF THE SEED STORAGE PROTEIN PHASEOLIN AT 3 ANGSTROMS RESOLUTION
Descriptor:PHASEOLIN, BETA-TYPE PRECURSOR
Authors:Lawrence, M.C., Suzuki, E., Varghese, J.N., Davis, P.C., Vandonkelaar, A., Tulloch, P.A., Colman, P.M.
Deposit date:1990-03-21
Release date:1990-10-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:The three-dimensional structure of the seed storage protein phaseolin at 3 A resolution.
EMBO J., 9, 1990
1V2I
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STRUCTURE OF THE HEMAGGLUTININ-NEURAMINIDASE FROM HUMAN PARAINFLUENZA VIRUS TYPE III
Descriptor:hemagglutinin-neuraminidase glycoprotein, 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Lawrence, M.C., Borg, N.A., Streltsov, V.A., Pilling, P.A., Epa, V.C., Varghese, J.N., McKimm-Breschkin, J.L., Colman, P.M.
Deposit date:2003-10-16
Release date:2004-02-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of the Haemagglutinin-neuraminidase from Human Parainfluenza Virus Type III
J.Mol.Biol., 335, 2004
1V3B
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STRUCTURE OF THE HEMAGGLUTININ-NEURAMINIDASE FROM HUMAN PARAINFLUENZA VIRUS TYPE III
Descriptor:hemagglutinin-neuraminidase glycoprotein, N-ACETYL-D-GLUCOSAMINE, CALCIUM ION, ...
Authors:Lawrence, M.C., Borg, N.A., Streltsov, V.A., Pilling, P.A., Epa, V.C., Varghese, J.N., McKimm-Breschkin, J.L., Colman, P.M.
Deposit date:2003-10-30
Release date:2004-02-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the Haemagglutinin-neuraminidase from Human Parainfluenza Virus Type III
J.Mol.Biol., 335, 2004
1V3C
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STRUCTURE OF THE HEMAGGLUTININ-NEURAMINIDASE FROM HUMAN PARAINFLUENZA VIRUS TYPE III: COMPLEX WITH NEU5AC
Descriptor:hemagglutinin-neuraminidase glycoprotein, N-ACETYL-D-GLUCOSAMINE, 5-N-ACETYL-BETA-D-NEURAMINIC ACID, ...
Authors:Lawrence, M.C., Borg, N.A., Streltsov, V.A., Pilling, P.A., Epa, V.C., Varghese, J.N., McKimm-Breschkin, J.L., Colman, P.M.
Deposit date:2003-10-30
Release date:2004-02-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of the Haemagglutinin-neuraminidase from Human Parainfluenza Virus Type III
J.Mol.Biol., 335, 2004
1V3D
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STRUCTURE OF THE HEMAGGLUTININ-NEURAMINIDASE FROM HUMAN PARAINFLUENZA VIRUS TYPE III: COMPLEX WITH NEU5AC2EN
Descriptor:hemagglutinin-neuraminidase glycoprotein, N-ACETYL-D-GLUCOSAMINE, CALCIUM ION, ...
Authors:Lawrence, M.C., Borg, N.A., Streltsov, V.A., Pilling, P.A., Epa, V.C., Varghese, J.N., McKimm-Breschkin, J.L., Colman, P.M.
Deposit date:2003-10-30
Release date:2004-02-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Structure of the Haemagglutinin-neuraminidase from Human Parainfluenza Virus Type III
J.Mol.Biol., 335, 2004
1V3E
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STRUCTURE OF THE HEMAGGLUTININ-NEURAMINIDASE FROM HUMAN PARAINFLUENZA VIRUS TYPE III: COMPLEX WITH ZANAMAVIR
Descriptor:hemagglutinin-neuraminidase glycoprotein, N-ACETYL-D-GLUCOSAMINE, CALCIUM ION, ...
Authors:Lawrence, M.C., Borg, N.A., Streltsov, V.A., Pilling, P.A., Epa, V.C., Varghese, J.N., McKimm-Breschkin, J.L., Colman, P.M.
Deposit date:2003-10-30
Release date:2004-02-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Structure of the Haemagglutinin-neuraminidase from Human Parainfluenza Virus Type III
J.Mol.Biol., 335, 2004
2BMB
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X-RAY STRUCTURE OF THE BIFUNCTIONAL 6-HYDROXYMETHYL-7,8- DIHYDROXYPTERIN PYROPHOSPHOKINASE DIHYDROPTEROATE SYNTHASE FROM SACCHAROMYCES CEREVISIAE
Descriptor:FOLIC ACID SYNTHESIS PROTEIN FOL1, PTERIN-6-YL-METHYL-MONOPHOSPHATE
Authors:Lawrence, M.C., Iliades, P., Fernley, R.T., Berglez, J., Pilling, P.A., Macreadie, I.G.
Deposit date:2005-03-11
Release date:2006-01-17
Last modified:2017-07-05
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The Three-Dimensional Structure of the Bifunctional 6-Hydroxymethyl-7,8-Dihydropterin Pyrophosphokinase/Dihydropteroate Synthase of Saccharomyces Cerevisiae
J.Mol.Biol., 348, 2005
1G5G
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FRAGMENT OF FUSION PROTEIN FROM NEWCASTLE DISEASE VIRUS
Descriptor:FUSION PROTEIN, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE
Authors:Lawrence, M.C., Smith, B.J.
Deposit date:2000-11-01
Release date:2002-02-27
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:The structure of the fusion glycoprotein of Newcastle disease virus suggests a novel paradigm for the molecular mechanism of membrane fusion.
Structure, 9, 2001
5KQV
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INSULIN RECEPTOR ECTODOMAIN CONSTRUCT COMPRISING DOMAINS L1,CR,L2, FNIII-1 AND ALPHACT PEPTIDE IN COMPLEX WITH BOVINE INSULIN AND FAB 83-14 (REVISED STRUCTURE)
Descriptor:Insulin, MONOCLONAL ANTIBODY FAB 83-14 - HEAVY CHAIN, MONOCLONAL ANTIBODY FAB 83-14 - LIGHT CHAIN, ...
Authors:Lawrence, M.C., Smith, B.J., Croll, T.I.
Deposit date:2016-07-06
Release date:2017-07-19
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (4.4 Å)
Cite:How insulin engages its primary binding site on the insulin receptor.
Nature, 493, 2013
3W11
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INSULIN RECEPTOR ECTODOMAIN CONSTRUCT COMPRISING DOMAINS L1-CR IN COMPLEX WITH HUMAN INSULIN, ALPHA-CT PEPTIDE(704-719) AND FAB 83-7
Descriptor:Insulin A chain, Insulin B chain, monoclonal antibody fab 83-7 fragment - heavy chain, ...
Authors:Lawrence, M.C., Smith, B.J.
Deposit date:2012-11-06
Release date:2013-01-09
Last modified:2013-09-04
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:How insulin engages its primary binding site on the insulin receptor
Nature, 493, 2013
3W12
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INSULIN RECEPTOR ECTODOMAIN CONSTRUCT COMPRISING DOMAINS L1-CR IN COMPLEX WITH HIGH-AFFINITY INSULIN ANALOGUE [D-PRO-B26]-DTI-NH2, ALPHA-CT PEPTIDE(704-719) AND FAB 83-7
Descriptor:Insulin receptor domains L1-CR, monoclonal antibody fab 83-7 fragment - heavy chain, monoclonal antibody fab 83-7 fragment - light chain, ...
Authors:Lawrence, M.C., Smith, B.J., Brzozowsk, A.M.
Deposit date:2012-11-06
Release date:2013-01-09
Last modified:2013-09-04
Method:X-RAY DIFFRACTION (4.301 Å)
Cite:How insulin engages its primary binding site on the insulin receptor
Nature, 493, 2013
3W13
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INSULIN RECEPTOR ECTODOMAIN CONSTRUCT COMPRISING DOMAINS L1-CR IN COMPLEX WITH HIGH-AFFINITY INSULIN ANALOGUE [D-PRO-B26]-DTI-NH2, ALPHACT PEPTIDE(693-719) AND FAB 83-7
Descriptor:Insulin receptor domains L1-CR, monoclonal antibody fab 83-7 fragment - heavy chain, monoclonal antibody fab 83-7 fragment - light chain, ...
Authors:Lawrence, M.C., Smith, B.J., Brzozowski, A.M.
Deposit date:2012-11-06
Release date:2013-01-09
Last modified:2013-09-04
Method:X-RAY DIFFRACTION (4.303 Å)
Cite:How insulin engages its primary binding site on the insulin receptor
Nature, 493, 2013
4OGA
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INSULIN IN COMPLEX WITH SITE 1 OF THE HUMAN INSULIN RECEPTOR
Descriptor:Insulin A chain, Insulin B chain, monoclonal antibody fab 83-7 fragment - heavy chain, ...
Authors:Lawrence, M.C., Menting, J.G.
Deposit date:2014-01-15
Release date:2014-08-27
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Protective hinge in insulin opens to enable its receptor engagement.
Proc.Natl.Acad.Sci.USA, 111, 2014
5EMS
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CRYSTAL STRUCTURE OF AN IODINATED INSULIN ANALOG
Descriptor:Insulin, PHENOL, ZINC ION, ...
Authors:Lawrence, M.C., Pandyarajan, V., Wan, Z., Weiss, M.A.
Deposit date:2015-11-06
Release date:2016-11-16
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Extending Halogen-based Medicinal Chemistry to Proteins: IODO-INSULIN AS A CASE STUDY.
J. Biol. Chem., 291, 2016
5JYQ
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STRUCTURE OF CONUS GEOGRAPHUS INSULIN G1
Descriptor:Insulin 1, Insulin 1b, SULFATE ION
Authors:Lawrence, M.C., Menting, J., Norton, R.S., Safavi-Hemami, H.
Deposit date:2016-05-15
Release date:2016-09-07
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:A minimized human insulin-receptor-binding motif revealed in a Conus geographus venom insulin.
Nat.Struct.Mol.Biol., 23, 2016
1F5Z
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CRYSTAL STRUCTURE ANALYSIS OF N-ACETYLNEURAMINATE LYASE FROM HAEMOPHILUS INFLUENZAE: CRYSTAL FORM I
Descriptor:N-ACETYLNEURAMINATE LYASE
Authors:Barbosa, J.A.R.G., Smith, B.J., DeGori, R., Lawrence, M.C.
Deposit date:2000-06-18
Release date:2000-12-20
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Active site modulation in the N-acetylneuraminate lyase sub-family as revealed by the structure of the inhibitor-complexed Haemophilus influenzae enzyme.
J.Mol.Biol., 303, 2000
1F6P
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CRYSTAL STRUCTURE ANALYSIS OF N-ACETYLNEURAMINATE LYASE FROM HAEMOPHILUS INFLUENZAE: CRYSTAL FORM III
Descriptor:N-ACETYL NEURAMINATE LYASE
Authors:Barbosa, J.A.R.G., Smith, B.J., DeGori, R., Lawrence, M.C.
Deposit date:2000-06-22
Release date:2000-11-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Active site modulation in the N-acetylneuraminate lyase sub-family as revealed by the structure of the inhibitor-complexed Haemophilus influenzae enzyme.
J.Mol.Biol., 303, 2000
1F6K
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CRYSTAL STRUCTURE ANALYSIS OF N-ACETYLNEURAMINATE LYASE FROM HAEMOPHILUS INFLUENZAE: CRYSTAL FORM II
Descriptor:N-ACETYLNEURAMINATE LYASE, SULFATE ION, GLYCEROL
Authors:Barbosa, J.A.R.G., Smith, B.J., DeGori, R., Lawrence, M.C.
Deposit date:2000-06-21
Release date:2000-12-20
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Active site modulation in the N-acetylneuraminate lyase sub-family as revealed by the structure of the inhibitor-complexed Haemophilus influenzae enzyme.
J.Mol.Biol., 303, 2000
1F73
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CRYSTAL STRUCTURE ANALYSIS OF N-ACETYLNEURAMINATE LYASE FROM HAEMOPHILUS INFLUENZAE: CRYSTAL FORM III IN COMPLEX WITH SIALIC ACID ALDITOL
Descriptor:N-ACETYL NEURAMINATE LYASE, 2,4,6,7,8,9-HEXAHYDROXY-5-METHYLCARBOXAMIDO NONANOIC ACID, GLYCEROL
Authors:Barbosa, J.A.R.G., Smith, B.J., DeGori, R., Lawrence, M.C.
Deposit date:2000-06-25
Release date:2000-11-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Active site modulation in the N-acetylneuraminate lyase sub-family as revealed by the structure of the inhibitor-complexed Haemophilus influenzae enzyme.
J.Mol.Biol., 303, 2000
1F74
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CRYSTAL STRUCTURE ANALYSIS OF N-ACETYLNEURAMINATE LYASE FROM HAEMOPHILUS INFLUENZAE: CRYSTAL FORM II COMPLEXED WITH 4-DEOXY-SIALIC ACID
Descriptor:N-ACETYL-NEURAMINATE LYASE, 6,7,8,9-TETRAHYDROXY-5-METHYLCARBOXAMIDO-2-OXONONANOIC ACID, GLYCEROL, ...
Authors:Barbosa, J.A.R.G., Smith, B.J., DeGori, R., Lawrence, M.C.
Deposit date:2000-06-26
Release date:2000-11-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Active site modulation in the N-acetylneuraminate lyase sub-family as revealed by the structure of the inhibitor-complexed Haemophilus influenzae enzyme.
J.Mol.Biol., 303, 2000
1F7B
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CRYSTAL STRUCTURE ANALYSIS OF N-ACETYLNEURAMINATE LYASE FROM HAEMOPHILUS INFLUENZAE: CRYSTAL FORM II IN COMPLEX WITH 4-OXO-SIALIC ACID
Descriptor:N-ACETYL-NEURAMINATE LYASE, 4,4,6,7,8,9-HEXAHYDROXY-5-METHYLCARBOXAMIDONONANOIC ACID, CHLORIDE ION, ...
Authors:Barbosa, J.A.R.G., Smith, B.J., DeGori, R., Lawrence, M.C.
Deposit date:2000-06-26
Release date:2000-11-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Active site modulation in the N-acetylneuraminate lyase sub-family as revealed by the structure of the inhibitor-complexed Haemophilus influenzae enzyme.
J.Mol.Biol., 303, 2000
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