1WZ9
| The 2.1 A structure of a tumour suppressing serpin | Descriptor: | Maspin precursor, SULFATE ION | Authors: | Law, R.H, Irving, J.A, Buckle, A.M, Ruzyla, K, Buzza, M, Bashtannyk-Puhalovich, T.A, Beddoe, T.C, Kim, N, Worrall, D.M, Bottomley, S.P, Bird, P.I, Rossjohn, J, Whisstock, J.C. | Deposit date: | 2005-03-03 | Release date: | 2005-03-15 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The high resolution crystal structure of the human tumor suppressor maspin reveals a novel conformational switch in the G-helix. J.Biol.Chem., 280, 2005
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3NSJ
| The X-ray crystal structure of lymphocyte perforin | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ... | Authors: | Law, R.H, Whisstock, J.C, Caradoc-Davies, T.T. | Deposit date: | 2010-07-01 | Release date: | 2010-11-03 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | The structural basis for membrane binding and pore formation by lymphocyte perforin. Nature, 468, 2010
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1XU8
| The 2.8 A structure of a tumour suppressing serpin | Descriptor: | Maspin, SULFATE ION | Authors: | Irving, J.A, Law, R.H, Ruzyla, K, Bashtannyk-Puhalovich, T.A, Kim, N, Worrall, D.M, Rossjohn, J, Whisstock, J.C. | Deposit date: | 2004-10-25 | Release date: | 2005-03-15 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | The high resolution crystal structure of the human tumor suppressor maspin reveals a novel conformational switch in the G-helix. J.Biol.Chem., 280, 2005
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2GPZ
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1YXA
| Serpina3n, a murine orthologue of human antichymotrypsin | Descriptor: | serine (or cysteine) proteinase inhibitor, clade A, member 3N | Authors: | Horvath, A.J, Irving, J.A, Law, R.H, Rossjohn, J, Bottomley, S.P, Quinsey, N.S, Pike, R.N, Coughlin, P.B, Whisstock, J.C. | Deposit date: | 2005-02-20 | Release date: | 2005-09-06 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The murine orthologue of human antichymotrypsin: a structural paradigm for clade A3 serpins. J.Biol.Chem., 280, 2005
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2VH4
| Structure of a loop C-sheet serpin polymer | Descriptor: | TENGPIN | Authors: | Zhang, Q, Law, R.H.P, Bottomley, S.P, Whisstock, J.C, Buckle, A.M. | Deposit date: | 2007-11-19 | Release date: | 2008-01-08 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | A Structural Basis for Loop C-Sheet Polymerization in Serpins. J.Mol.Biol., 376, 2008
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3JZ4
| Crystal structure of E. coli NADP dependent enzyme | Descriptor: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Succinate-semialdehyde dehydrogenase [NADP+] | Authors: | Langendorf, C.G, Key, T.L.G, Fenalti, G, Kan, W.T, Buckle, A.M, Caradoc-Davies, T, Tuck, K.L, Law, R.H.P, Whisstock, J.C. | Deposit date: | 2009-09-22 | Release date: | 2010-03-16 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The X-ray crystal structure of Escherichia coli succinic semialdehyde dehydrogenase; structural insights into NADP+/enzyme interactions. Plos One, 5, 2010
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3W56
| Structure of a C2 domain | Descriptor: | C2 domain protein | Authors: | Traore, D.A.K, Whisstock, J.C. | Deposit date: | 2013-01-24 | Release date: | 2013-10-23 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Defining the interaction of perforin with calcium and the phospholipid membrane. Biochem.J., 456, 2013
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3W57
| Structure of a C2 domain | Descriptor: | C2 domain protein, CALCIUM ION | Authors: | Traore, D.A.K, Whisstock, J.C. | Deposit date: | 2013-01-24 | Release date: | 2013-10-23 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.662 Å) | Cite: | Defining the interaction of perforin with calcium and the phospholipid membrane. Biochem.J., 456, 2013
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4ES8
| Crystal Structure of the adhesin domain of Epf from Streptococcus pyogenes in P212121 | Descriptor: | ACETATE ION, Epf, GLYCEROL, ... | Authors: | Linke, C, Siemens, N, Kreikemeyer, B, Baker, E.N. | Deposit date: | 2012-04-23 | Release date: | 2012-09-19 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | The Extracellular Protein Factor Epf from Streptococcus pyogenes Is a Cell Surface Adhesin That Binds to Cells through an N-terminal Domain Containing a Carbohydrate-binding Module. J.Biol.Chem., 287, 2012
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4OEJ
| Structure of membrane binding protein pleurotolysin B from Pleurotus ostreatus | Descriptor: | ACETATE ION, CHLORIDE ION, GLYCEROL, ... | Authors: | Dunstone, M.A, Caradoc-Davies, T.T, Whisstock, J.C, Law, R.H.P. | Deposit date: | 2014-01-13 | Release date: | 2015-02-18 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Conformational Changes during Pore Formation by the Perforin-Related Protein Pleurotolysin. Plos Biol., 13, 2015
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4OEB
| Structure of membrane binding protein pleurotolysin A from Pleurotus ostreatus | Descriptor: | Pleurotolysin A, SULFATE ION | Authors: | Dunstone, M.A, Caradoc-Davies, T.T, Whisstock, J.C, Law, R.H.P. | Deposit date: | 2014-01-12 | Release date: | 2015-02-18 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Conformational Changes during Pore Formation by the Perforin-Related Protein Pleurotolysin. Plos Biol., 13, 2015
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4P48
| The structure of a chicken anti-cardiac Troponin I scFv | Descriptor: | Antibody scFv 180 | Authors: | Conroy, P.J, Law, R.H.P, Gillgunn, S, Hearty, S, Caradoc-Davies, T.T, Llyod, G, O'Kennedy, R.J, Whisstock, J.C. | Deposit date: | 2014-03-12 | Release date: | 2014-04-23 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Reconciling the structural attributes of avian antibodies. J.Biol.Chem., 289, 2014
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4P49
| The structure of a chicken anti-prostate specific antigen scFv | Descriptor: | ACETATE ION, Antibody scFv B8, SULFATE ION | Authors: | Conroy, P.J, Law, R.H.P, Gilgunn, S, Hearty, S, Llyod, G, Caradoc-Davies, T.T, O'Kennedy, R.J, Whisstock, J.C. | Deposit date: | 2014-03-12 | Release date: | 2014-04-23 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Reconciling the structural attributes of avian antibodies. J.Biol.Chem., 289, 2014
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2OKK
| The X-ray crystal structure of the 65kDa isoform of Glutamic Acid Decarboxylase (GAD65) | Descriptor: | GAMMA-AMINO-BUTANOIC ACID, GLYCEROL, Glutamate decarboxylase 2 | Authors: | Buckle, A.M, Fenalti, G, Law, R.H.P, Whisstock, J.C. | Deposit date: | 2007-01-17 | Release date: | 2007-03-27 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | GABA production by glutamic acid decarboxylase is regulated by a dynamic catalytic loop. Nat.Struct.Mol.Biol., 14, 2007
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2QP2
| Structure of a MACPF/perforin-like protein | Descriptor: | CALCIUM ION, Unknown protein | Authors: | Rosado, C.J, Buckle, A.M, Law, R.H.P, Butcher, R.E, Kan, W.T, Bird, C.H, Ung, K, Browne, K.A, Baran, K, Bashtannyk-Puhalovich, T.A, Faux, N.G, Wong, W, Porter, C.J, Pike, R.N, Ellisdon, A.M, Pearce, M.C, Bottomley, S.P, Emsley, J, Smith, A.I, Rossjohn, J, Hartland, E.L, Voskoboinik, I, Trapani, J.A, Bird, P.I, Dunstone, M.A, Whisstock, J.C. | Deposit date: | 2007-07-22 | Release date: | 2007-09-04 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A common fold mediates vertebrate defense and bacterial attack Science, 317, 2007
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4ES9
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4F88
| X-ray Crystal Structure of PlyC | Descriptor: | PlyCA, PlyCB | Authors: | McGowan, S, Buckle, A.M, Fischetti, V.A, Nelson, D.C, Whisstock, J.C. | Deposit date: | 2012-05-17 | Release date: | 2012-07-25 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | X-ray crystal structure of the streptococcal specific phage lysin PlyC. Proc.Natl.Acad.Sci.USA, 109, 2012
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4F87
| X-ray Crystal Structure of PlyCB | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, PlyCB | Authors: | McGowan, S, Buckle, A.M, Fischetti, V.A, Nelson, D.C, Whisstock, J.C. | Deposit date: | 2012-05-17 | Release date: | 2012-07-25 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | X-ray crystal structure of the streptococcal specific phage lysin PlyC. Proc.Natl.Acad.Sci.USA, 109, 2012
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4Y1S
| Structural basis for Ca2+-mediated interaction of the perforin C2 domain with lipid membranes | Descriptor: | CALCIUM ION, Perforin-1 | Authors: | Conroy, P.J, Yagi, H, Whisstock, J.C, Norton, R.S. | Deposit date: | 2015-02-09 | Release date: | 2015-09-02 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.611 Å) | Cite: | Structural Basis for Ca2+-mediated Interaction of the Perforin C2 Domain with Lipid Membranes. J.Biol.Chem., 290, 2015
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4Y1T
| Structural basis for Ca2+-mediated interaction of the perforin C2 domain with lipid membranes | Descriptor: | CALCIUM ION, Perforin-1 | Authors: | Conroy, P.J, Yagi, H, Whisstock, J.C, Norton, R.S. | Deposit date: | 2015-02-09 | Release date: | 2015-09-02 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.666 Å) | Cite: | Structural Basis for Ca2+-mediated Interaction of the Perforin C2 Domain with Lipid Membranes. J.Biol.Chem., 290, 2015
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3H7O
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3H7T
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4P0O
| Cleaved Serpin 42Da | Descriptor: | Serine protease inhibitor 4, isoform B | Authors: | Ellisdon, A.M, Whisstock, J.C. | Deposit date: | 2014-02-21 | Release date: | 2014-05-07 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | High resolution structure of cleaved Serpin 42 Da from Drosophila melanogaster. Bmc Struct.Biol., 14, 2014
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4P0F
| Cleaved Serpin 42Da (C 2 2 21) | Descriptor: | Serine protease inhibitor 4, isoform B | Authors: | Ellisdon, A.M, Whisstock, J.C. | Deposit date: | 2014-02-21 | Release date: | 2014-05-07 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | High resolution structure of cleaved Serpin 42 Da from Drosophila melanogaster. Bmc Struct.Biol., 14, 2014
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