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2SNM
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BU of 2snm by Molmil
IN A STAPHYLOCOCCAL NUCLEASE MUTANT THE SIDE-CHAIN of A LYSINE REPLACING VALINE 66 IS FULLY BURIED IN THE HYDROPHOBIC CORE
Descriptor: CALCIUM ION, STAPHYLOCOCCAL NUCLEASE, THYMIDINE-3',5'-DIPHOSPHATE
Authors:Stites, W.E, Gittis, A.G, Lattman, E.E, Shortle, D.
Deposit date:1991-04-03
Release date:1993-01-15
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:In a staphylococcal nuclease mutant the side-chain of a lysine replacing valine 66 is fully buried in the hydrophobic core.
J.Mol.Biol., 221, 1991
2ENB
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BU of 2enb by Molmil
CRYSTAL STRUCTURES OF THE BINARY CA2+ AND PDTP COMPLEXES AND THE TERNARY COMPLEX OF THE ASP 21->GLU MUTANT OF STAPHYLOCOCCAL NUCLEASE. IMPLICATIONS FOR CATALYSIS AND LIGAND BINDING
Descriptor: STAPHYLOCOCCAL NUCLEASE, THYMIDINE-3',5'-DIPHOSPHATE
Authors:Libson, A, Gittis, A, Lattman, E.E.
Deposit date:1994-03-23
Release date:1994-05-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal structures of the binary Ca2+ and pdTp complexes and the ternary complex of the Asp21-->Glu mutant of staphylococcal nuclease. Implications for catalysis and ligand binding.
Biochemistry, 33, 1994
1PRQ
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BU of 1prq by Molmil
ACANTHAMOEBA CASTELLANII PROFILIN IA
Descriptor: PROFILIN IA
Authors:Fedorov, A.A, Pollard, T.D, Way, M, Lattman, E.E, Almo, S.C.
Deposit date:1997-08-18
Release date:1997-12-24
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal packing induces a conformational change in profilin-I from Acanthamoeba castellanii.
J.Struct.Biol., 123, 1998
2OEO
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BU of 2oeo by Molmil
Cryogenic crystal structure of Staphylococcal Nuclease variant truncated Delta+PHS I92D
Descriptor: CALCIUM ION, Staphylococcal thermonuclease, THYMIDINE-3',5'-DIPHOSPHATE
Authors:Reynald, R.L, Lattman, E.E, Gittis, A.G.
Deposit date:2006-12-30
Release date:2008-03-25
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Buried Charges and Water in the Protein Interior: Reality or Fiction?
To be Published
2PRF
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BU of 2prf by Molmil
THREE DIMENSIONAL SOLUTION STRUCTURE OF ACANTHAMOEBA PROFILIN I
Descriptor: PROFILIN IA
Authors:Archer, S.J, Vinson, V.K, Pollard, T.D, Lattman, E.E, Torchia, D.A.
Deposit date:1994-01-12
Release date:1994-05-31
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Three-dimensional solution structure of Acanthamoeba profilin-I.
J.Cell Biol., 122, 1993
1STB
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BU of 1stb by Molmil
ACCOMMODATION OF INSERTION MUTATIONS ON THE SURFACE AND IN THE INTERIOR OF STAPHYLOCOCCAL NUCLEASE
Descriptor: CALCIUM ION, STAPHYLOCOCCAL NUCLEASE, THYMIDINE-3',5'-DIPHOSPHATE
Authors:Quirk, S, Gittis, A, Keefe, L.J, Lattman, E.E.
Deposit date:1994-01-17
Release date:1994-07-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Accommodation of insertion mutations on the surface and in the interior of staphylococcal nuclease.
Protein Sci., 3, 1994
1STA
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BU of 1sta by Molmil
ACCOMMODATION OF INSERTION MUTATIONS ON THE SURFACE AND IN THE INTERIOR OF STAPHYLOCOCCAL NUCLEASE
Descriptor: CALCIUM ION, STAPHYLOCOCCAL NUCLEASE, THYMIDINE-3',5'-DIPHOSPHATE
Authors:Keefe, L.J, Quirk, S, Gittis, A, Lattman, E.E.
Deposit date:1994-01-17
Release date:1994-06-22
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Accommodation of insertion mutations on the surface and in the interior of staphylococcal nuclease.
Protein Sci., 3, 1994
1ZJG
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BU of 1zjg by Molmil
13mer-co
Descriptor: 5'-D(*AP*TP*GP*GP*GP*GP*CP*GP*GP*GP*GP*CP*T)-3', 5'-D(*TP*AP*GP*CP*CP*CP*CP*GP*CP*CP*CP*CP*A)-3', COBALT HEXAMMINE(III), ...
Authors:Dohm, J.A, Hsu, M.H, Hwu, J.R, Huang, R.C, Moudrianakis, E.N, Lattman, E.E, Gittis, A.G.
Deposit date:2005-04-28
Release date:2005-05-10
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3 Å)
Cite:Influence of Ions, Hydration, and the Transcriptional Inhibitor P4N on the Conformations of the Sp1 Binding Site.
J.Mol.Biol., 349, 2005
1ZJF
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BU of 1zjf by Molmil
12mer-spd-P4N
Descriptor: 5'-D(*AP*GP*GP*GP*GP*CP*GP*GP*GP*GP*CP*T)-3', 5'-D(*TP*AP*GP*CP*CP*CP*CP*GP*CP*CP*CP*C)-3'
Authors:Dohm, J.A, Hsu, M.H, Hwu, J.R, Huang, R.C, Moudrianakis, E.N, Lattman, E.E, Gittis, A.G.
Deposit date:2005-04-28
Release date:2005-05-10
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Influence of Ions, Hydration, and the Transcriptional Inhibitor P4N on the Conformations of the Sp1 Binding Site.
J.Mol.Biol., 349, 2005
1ZJE
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BU of 1zje by Molmil
12mer-spd
Descriptor: 5'-D(*AP*GP*GP*GP*GP*CP*GP*GP*GP*GP*CP*T)-3', 5'-D(*TP*AP*GP*CP*CP*CP*CP*GP*CP*CP*CP*C)-3'
Authors:Dohm, J.A, Hsu, M.H, Hwu, J.R, Huang, R.C, Moudrianakis, E.N, Lattman, E.E, Gittis, A.G.
Deposit date:2005-04-28
Release date:2005-05-10
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Influence of Ions, Hydration, and the Transcriptional Inhibitor P4N on the Conformations of the Sp1 Binding Site.
J.Mol.Biol., 349, 2005
2ACG
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BU of 2acg by Molmil
ACANTHAMOEBA CASTELLANII PROFILIN II
Descriptor: PROFILIN II
Authors:Fedorov, A.A, Magnus, K.A, Graupe, M.H, Lattman, E.E, Pollard, T.D, Almo, S.C.
Deposit date:1994-08-30
Release date:1994-11-01
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:X-ray structures of isoforms of the actin-binding protein profilin that differ in their affinity for phosphatidylinositol phosphates.
Proc.Natl.Acad.Sci.USA, 91, 1994
1HC8
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BU of 1hc8 by Molmil
CRYSTAL STRUCTURE OF A CONSERVED RIBOSOMAL PROTEIN-RNA COMPLEX
Descriptor: 58 NUCLEOTIDE RIBOSOMAL 23S RNA DOMAIN, MAGNESIUM ION, OSMIUM ION, ...
Authors:Conn, G.L, Draper, D.E, Lattman, E.E, Gittis, A.G.
Deposit date:2001-04-27
Release date:2002-05-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A Compact RNA Tertiary Structure Contains a Buried Backbone-K+ Complex
J.Mol.Biol., 318, 2002
1SNM
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BU of 1snm by Molmil
ACTIVE SITE MUTANT GLU-43 (RIGHT ARROW) ASP IN STAPHYLOCOCCAL NUCLEASE DISPLAYS NONLOCAL STRUCTURAL CHANGES
Descriptor: CALCIUM ION, THERMONUCLEASE PRECURSOR, THYMIDINE-3',5'-DIPHOSPHATE
Authors:Loll, P.J, Lattman, E.E.
Deposit date:1990-02-15
Release date:1991-07-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Active site mutant Glu-43 --> Asp in staphylococcal nuclease displays nonlocal structural changes.
Biochemistry, 29, 1990
1STY
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BU of 1sty by Molmil
THE ALPHA ANEURISM: A STRUCTURAL MOTIF REVEALED IN AN INSERTION MUTANT OF STAPHYLOCOCCAL NUCLEASE
Descriptor: CALCIUM ION, STAPHYLOCOCCAL NUCLEASE, THYMIDINE-3',5'-DIPHOSPHATE
Authors:Keefe, L.J, Lattman, E.E.
Deposit date:1993-02-18
Release date:1993-04-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:The alpha aneurism: a structural motif revealed in an insertion mutant of staphylococcal nuclease.
Proc.Natl.Acad.Sci.USA, 90, 1993
1QA6
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BU of 1qa6 by Molmil
CRYSTAL STRUCTURE OF A CONSERVED RIBOSOMAL PROTEIN-RNA COMPLEX
Descriptor: 58 NUCLEOTIDE RIBOSOMAL RNA DOMAIN, MAGNESIUM ION, OSMIUM ION, ...
Authors:Conn, G.L, Draper, D.E, Lattman, E.E, Gittis, A.G.
Deposit date:1999-04-15
Release date:1999-05-25
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of a conserved ribosomal protein-RNA complex.
Science, 284, 1999
1REI
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BU of 1rei by Molmil
THE MOLECULAR STRUCTURE OF A DIMER COMPOSED OF THE VARIABLE PORTIONS OF THE BENCE-JONES PROTEIN REI REFINED AT 2.0 ANGSTROMS RESOLUTION
Descriptor: BENCE-JONES PROTEIN REI (LIGHT CHAIN)
Authors:Epp, O, Lattman, E.E, Colman, P, Fehlhammer, H, Bode, W, Schiffer, M, Huber, R, Palm, W.
Deposit date:1976-03-17
Release date:1976-05-19
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:The molecular structure of a dimer composed of the variable portions of the Bence-Jones protein REI refined at 2.0-A resolution.
Biochemistry, 14, 1975
1GEN
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BU of 1gen by Molmil
C-TERMINAL DOMAIN OF GELATINASE A
Descriptor: CALCIUM ION, CHLORIDE ION, GELATINASE A, ...
Authors:Libson, A.M, Gittis, A.G, Collier, I.E, Marmer, B.L, Goldberg, G.G, Lattman, E.E.
Deposit date:1995-07-19
Release date:1996-08-17
Last modified:2018-03-21
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystal structure of the haemopexin-like C-terminal domain of gelatinase A.
Nat.Struct.Biol., 2, 1995
1SNC
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BU of 1snc by Molmil
THE CRYSTAL STRUCTURE OF THE TERNARY COMPLEX OF STAPHYLOCOCCAL NUCLEASE, CA2+, AND THE INHIBITOR PD*TP, REFINED AT 1.65 ANGSTROMS
Descriptor: CALCIUM ION, THERMONUCLEASE PRECURSOR, THYMIDINE-3',5'-DIPHOSPHATE
Authors:Loll, P.J, Lattman, E.E.
Deposit date:1989-07-21
Release date:1990-10-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:The crystal structure of the ternary complex of staphylococcal nuclease, Ca2+, and the inhibitor pdTp, refined at 1.65 A.
Proteins, 5, 1989
1SND
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BU of 1snd by Molmil
STAPHYLOCOCCAL NUCLEASE DIMER CONTAINING A DELETION OF RESIDUES 114-119 COMPLEXED WITH CALCIUM CHLORIDE AND THE COMPETITIVE INHIBITOR DEOXYTHYMIDINE-3',5'-DIPHOSPHATE
Descriptor: STAPHYLOCOCCAL NUCLEASE DIMER
Authors:Green, S.M, Gittis, A.G, Meeker, A.K, Lattman, E.E.
Deposit date:1996-08-23
Release date:1997-04-21
Last modified:2022-12-21
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:One-step evolution of a dimer from a monomeric protein.
Nat.Struct.Biol., 2, 1995
1STH
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BU of 1sth by Molmil
TWO DISTINCTLY DIFFERENT METAL BINDING MODES ARE SEEN IN X-RAY CRYSTAL STRUCTURES OF STAPHYLOCOCCAL NUCLEASE-COBALT(II)-NUCLEOTIDE COMPLEXES
Descriptor: COBALT (II) ION, STAPHYLOCOCCAL NUCLEASE, THYMIDINE-3',5'-DIPHOSPHATE
Authors:Loll, P.J, Quirk, S, Lattman, E.E.
Deposit date:1994-10-27
Release date:1995-02-27
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:X-ray crystal structures of staphylococcal nuclease complexed with the competitive inhibitor cobalt(II) and nucleotide.
Biochemistry, 34, 1995
1STG
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BU of 1stg by Molmil
TWO DISTINCTLY DIFFERENT METAL BINDING MODES ARE SEEN IN X-RAY CRYSTAL STRUCTURES OF STAPHYLOCOCCAL NUCLEASE-COBALT(II)-NUCLEOTIDE COMPLEXES
Descriptor: COBALT (II) ION, STAPHYLOCOCCAL NUCLEASE, THYMIDINE-3',5'-DIPHOSPHATE
Authors:Loll, P.J, Quirk, S, Lattman, E.E.
Deposit date:1994-10-27
Release date:1995-01-26
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:X-ray crystal structures of staphylococcal nuclease complexed with the competitive inhibitor cobalt(II) and nucleotide.
Biochemistry, 34, 1995
1TR5
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BU of 1tr5 by Molmil
Room temperature structure of Staphylococcal nuclease variant truncated Delta+PHS I92E
Descriptor: CALCIUM ION, THYMIDINE-3',5'-DIPHOSPHATE, Thermonuclease
Authors:Nguyen, D.M, Leila Reynald, R, Gittis, A.G, Lattman, E.E.
Deposit date:2004-06-20
Release date:2004-07-06
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:X-ray and thermodynamic studies of staphylococcal nuclease variants I92E and I92K: insights into polarity of the protein interior
J.Mol.Biol., 341, 2004
1TT2
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BU of 1tt2 by Molmil
Cryogenic crystal structure of Staphylococcal nuclease variant truncated Delta+PHS I92K
Descriptor: CALCIUM ION, DIMETHYL SULFOXIDE, GLYCEROL, ...
Authors:Nguyen, D.M, Reynald, R.L, Gittis, A.G, Lattman, E.E.
Deposit date:2004-06-21
Release date:2004-07-06
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:X-ray and thermodynamic studies of staphylococcal nuclease variants I92E and I92K: insights into polarity of the protein interior
J.Mol.Biol., 341, 2004
1TQO
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BU of 1tqo by Molmil
Cryogenic Crystal Structure of Staphylococcal Nuclease Variant truncated Delta+PHS I92E
Descriptor: Thermonuclease
Authors:Nguyen, D.M, Reynald, R.L, Gittis, A.G, Lattman, E.E.
Deposit date:2004-06-17
Release date:2004-07-06
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:X-ray and thermodynamic studies of staphylococcal nuclease variants I92E and I92K: insights into polarity of the protein interior
J.Mol.Biol., 341, 2004
1ACF
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BU of 1acf by Molmil
ACANTHAMOEBA CASTELLANII PROFILIN IB
Descriptor: PROFILIN I
Authors:Fedorov, A.A, Magnus, K.A, Graupe, M.H, Lattman, E.E, Pollard, T.D, Almo, S.C.
Deposit date:1994-07-29
Release date:1994-08-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:X-ray structures of isoforms of the actin-binding protein profilin that differ in their affinity for phosphatidylinositol phosphates.
Proc.Natl.Acad.Sci.USA, 91, 1994

 

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